IL-17 and IL-22 in Cerebrospinal Fluid and Plasma Are Elevated in Guillain-Barré Syndrome by Shujuan Li, Ming Yu, Haifeng Li, Hongliang Zhang, Yanfang Jiang

“…We hypothesized that interleukin (IL)-17 and IL-22 are elevated in GBS and participate in the autoimmune inflammatory response of GBS. We used sandwich enzyme-linked immunosorbent assay (ELISA) to measure the IL-17 and IL-22 levels in the CSF, and plasma from 22 GBS patients at the acute phase and 18 healthy controls (HC). …”
Get full text

Hepatoprotective effect anti-inflammatory and antioxidant Ganoderma lucidum ethanol extract on rats exposed to Plumbum acetate by Hernayanti, Laksana Agung, Saryono, Jehloh Latifah

“…Pb exposure also induces a hepatic inflammatory response characterized by an increase in TNFα. …”
Get full text

Heparin Interaction with the Primed Polymorphonuclear Leukocyte CD11b Induces Apoptosis and Prevents Cell Activation by Meital Cohen-Mazor, Rafi Mazor, Batya Kristal, Erik B. Kistler, Inbal Ziv, Judith Chezar, Shifra Sela

“…To test our hypothesis, we designed both in vitro and ex vivo studies to elucidate the mechanism by which heparin modulates PMNL functions and therefore the inflammatory response. We specifically tested the hypothesis that priming of PMNLs renders them more susceptible to heparin. …”
Get full text

Salmonella enteridis Septic Arthritis: A Report of Two Cases by Esat Uygur, Krishna Reddy, Feyza Ünlü Özkan, Salih Söylemez, Özlem Aydin, Serkan Şenol

“…Clinicians should be cautious that the white blood cell count in synovial fluid can be under 50.000/mm3 in immune compromised individuals with septic arthritis. The inflammatory response can be deficient, or the microorganism may be atypical. …”
Get full text

The systemic immune state of super-shedder mice is characterized by a unique neutrophil-dependent blunting of TH1 responses. by Smita Gopinath, Andrew Hotson, Jennifer Johns, Garry Nolan, Denise Monack

“…Compared to moderate shedders, super-shedder mice had an active inflammatory response in both the gastrointestinal tract and the spleen but a dampened T(H)1 response specific to the secondary lymphoid organs. …”
Get full text

A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer by David G. Watt, Campbell S. Roxburgh, Mark White, Juen Zhik Chan, Paul G. Horgan, Donald C. McMillan

“…Introduction. The systemic inflammatory response (SIR) plays a key role in determining nutritional status and survival of patients with cancer. …”
Get full text

The potential of melatonin in sepsis-associated acute kidney injury: Mitochondrial protection and cGAS-STING signaling pathway by Yuchun Cao, Xiaofang He, Zeyuan Liu, Liying Miao, Bin Zhu

“…We propose the protective effects of Mel on mitochondria are closely related to the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling pathway in the immune-inflammatory response. We intraperitoneally injected H151 and Mel into SA-AKI mouse models to interfere the cGAS-STING signaling pathway. …”
Get full text

The Anti-Inflammatory Effect of Callicarpa nudiflora Extract on H. Pylori-Infected GES-1 Cells through the Inhibition of ROS/NLRP3/Caspase-1/IL-1β Signaling Axis by Lili Li, Bo Bao, Xingxing Chai, Xiaoyu Chen, Xiaohua Su, Shixiu Feng, Xiaohui Zhu

“…To sum up, CN is highly protective against H. pylori-induced cell damage and apoptosis; CN can depress NLRP3 inflammasome activation and ROS production via the ROS/NLRP3/caspase-1/IL-1β signaling axis to suppress H. pylori-triggered inflammatory response and pyroptosis.…”
Get full text

Arsenic Induces Continuous Inflammation and Regulates Th1/Th2/Th17/Treg Balance in Liver and Kidney In Vivo by Xiaoxu Duan, Guowei Xu, Jinlong Li, Nan Yan, Xin Li, Xuping Liu, Bing Li

“…In conclusion, the results of the study suggested that arsenic induces continuous immune-inflammatory responses in the liver and kidney.…”
Get full text

Intraocular inflammation after intravitreal injection of aflibercept 8 mg for treatment-refractory neovascular age-related macular degeneration: a case report by Nozomu Hashiya, Ichiro Maruko, Yuri Miyaguchi, Ruka Maruko, Taiji Hasegawa, Tomohiro Iida

“…Conclusions This case demonstrated a potential dose-dependent inflammatory response following aflibercept 8 mg, which did not occur with aflibercept 2 mg in patients with a history of intraocular inflammation.…”
Get full text

Pancreatopleural fistula as a complication of necrotizing pancreatitis (clinical case) by V.I. Desyateryk, O.V. Kotov, S.P. Mikhno, Ye.O. Okhotnik, M.P. Krasnov

“…Acute pancreatitis is a disease that is accompanied by systemic inflammatory response syndrome and polysystemic dysfunction. …”
Get full text

Prognosis of Severe Covid-19 patients after treatment with Therapeutic Plasma Exchange (TPE) by Maliha Khalid, Faheem Feroze, Saad Bin Qamar, Naseem Abbas, Saeed Farooq, Aisha Siddiqui

“…Literature study showed  that  in severe  Covid-19  patients, a hyper-inflammatory response  to  initial  infection could accelerate  to  severe  hyper-cytokinaemia that  could  lead to  an  underlying endothelial  dysfunction and multiple organ dysfunction. …”
Get full text

Cellular aspects of immunity involved in the development of atherosclerosis by Khalil Khalaf, Khalil Khalaf, Khalil Khalaf, Marc Chamieh, Natalia Welc, Chandpreet Singh, Joanne Lynn Kaouk, Aiden Kaouk, Andrzej Mackiewicz, Andrzej Mackiewicz, Mariusz Kaczmarek, Mariusz Kaczmarek, Bartlomiej Perek

“…The hardening of arterial vessels characterizes atherosclerosis due to the accumulation of lipids in the arterial walls, eliciting an inflammatory response. The development of atherosclerosis occurs in various stages and is facilitated by many clinical factors, such as hypertension, hyperlipidemia, and inflammatory status. …”
Get full text

Anti-Inflammatory Effect of By-Products from Haliotis discus hannai in RAW 264.7 Cells by Ho-Seok Rho, Hyang Kim, Jung-Ae Kim, Fatih Karadeniz, Byul-Nim Ahn, Ki-Ho Nam, Youngwan Seo, Chang-Suk Kong

“…Also, AM was shown to increase expression of anti-inflammatory response mediator HO-1. Presence of AM also scavenged the free radicals in vitro. …”
Get full text

Combined detection of monocyte distribution width and procalcitonin for diagnosing and prognosing neonatal sepsis by Jiaping Wang, Ming Hu, Na Wang, Tingting Huang, Huiyi Wu, Hua Li

“…Methods This retrospective study, conducted from January 2022 to December 2023.A retrospective analysis of 39 neonatal sepsis and 30 non-infectious systemic inflammatory response syndrome (SIRS) cases was conducted. …”
Get full text

Effectiveness of ethanol extract of Morinda citrifolia L. as an anti-inflammatory: A preclinical study by Mega Hayati, Ali Napiah Nasution, Ermi Girsang, Adek Amansyah, Fioni

“…The inflammatory response is triggered by infections or tissue damage, often requiring effective anti-inflammatory treatments. …”
Get full text

Galectin-10 Is Released in the Nasal Lavage Fluid of Patients with Aspirin-Sensitive Respiratory Disease by Ma. Cristina Negrete-Garcia, Carla Yoneli Jiménez-Torres, Noe Alvarado-Vásquez, A. Rosalía Montes-Vizuet, J. R. Velázquez-Rodriguez, M. Carmen Jimenez-Martinez, Luis Manuel Teran-Juárez

“…Our results suggest a probable role of galectin-10 in the inflammatory response observed in ASRD patients; however, confirmatory studies are needed.…”
Get full text

Do the Th17 Cells Play a Role in the Pathogenesis of Leptospirosis? by Kanchana Bandara, Chinthika Gunasekara, Manjula Weerasekera, Chamil Marasinghe, Nilantha Ranasinghe, Neluka Fernando

“…The aim of this study was to determine the level of five different pro- and anti-inflammatory cytokines to study the inflammatory response of leptospirosis. Materials and methods. …”
Get full text

A systematic review and meta-analysis of the association between galectin-3 levels and clinical outcomes in COVID-19 patients by Kacper DZIEDZIC, Kavita BATRA, Michal PRUC, Monika TOMASZEWSKA, Krzysztof KUREK, Murat YILDIRIM, Mahmood BAHRAMIZADEH, Francesco CHIRICO, Nicola Luigi BRAGAZZI, Hicham KHABBACHE, Aldo SITIBONDO, Lukasz SZARPAK, Gabriella NUCERA

“…Introduction: Galectin-3 is a β-galactoside-binding lectin with several roles in the immune- inflammatory response. The aim of this systematic review and meta-analysis was to explain the prognostic value of Galectin-3 on COVID-19 severity and mortality from the existing literature. …”
Get full text

Langerhans Cells, T Cells, and B Cells in Oral Lichen Planus and Oral Leukoplakia by Amal Dafar, Angelica Siarov, Yasaman Mostaghimi, Jairo Robledo-Sierra, Shahin De Lara, Daniel Giglio, Göran Kjeller, Paulo Henrique Braz-Silva, Jenny Öhman, Bengt Hasséus

“…Although the number of B cells in LPL is low, their role in the inflammatory response cannot be ruled out.…”
Get full text