Regulatory Role of GSK-3β on NF-κB, Nitric Oxide, and TNF-α in Group A Streptococcal Infection by Yu-Tzu Chang, Chia-Ling Chen, Chiou-Feng Lin, Shiou-Ling Lu, Miao-Huei Cheng, Chih-Feng Kuo, Yee-Shin Lin

“…Glycogen synthase kinase-3β (GSK-3β) is known to regulate inflammatory response in infectious diseases. However, the regulation of GSK-3β in GAS infection is still unknown. …”
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Effect of Toll-Like Receptor 4 on Synovial Injury of Temporomandibular Joint in Rats Caused by Occlusal Interference by Jingjing Kong, Yingying Yang, Shuzhen Sun, Jianli Xie, Xuefen Lin, Ping Ji

“…In the current study, we investigated whether or not TLR4 participates in the inflammatory responses and the expression of IL-1β in synovial membrane of rats induced by occlusal interference. …”
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IFN Regulatory Factor 1 Mediates Macrophage Pyroptosis Induced by Oxidized Low-Density Lipoprotein in Patients with Acute Coronary Syndrome by Min Guo, Rui Yan, Hongmei Yao, Liqin Duan, Meng Sun, Zheng Xue, Yongping Jia

“…Further experiments revealed that pyroptosis and the downstream inflammatory response in AS induced by IRF-1 is a process that is dependent on reactive oxygen species (ROS) generation. …”
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Schisandrin B Attenuates Airway Inflammation by Regulating the NF-κB/Nrf2 Signaling Pathway in Mouse Models of Asthma by Yaqin Chen, Yu Kong, Qili Wang, Jian Chen, Hua Chen, Huihui Xie, Lan Li

“…Moreover, schisandrin B administration suppressed inflammatory responses, reduced the level of IgE, and attenuated pathological injury. …”
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Untargeted metabolomic and proteomic analysis implicates SIRT2 as a novel therapeutic target for diabetic nephropathy by Ruijing Zhang, Runze Chang, Heng Wang, Jinshan Chen, Chuanlong Lu, Keyi Fan, Yuhang Zhang, Lizheng Li, Sheng Yan, Honglin Dong

“…KEGG enrichment analysis showed that HIF-1 signaling pathway and renal cell carcinoma pathway were co-enriched pathways in energy metabolism and inflammatory response. VEGFA plays a vital role in these two signaling pathways. …”
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Biosynthetic pathway for leukotrienes is stimulated by lipopolysaccharide and cytokines in pig endometrial stromal cells by Barbara Jana, Aneta Andronowska, Jarosław Całka, Aleksandra Mówińska

“…Abstract An inflammatory response is related to different inflammatory mediators generated by immune and endometrial cells. …”
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Gene Expression Profiling in Dermatitis Herpetiformis Skin Lesions by M. Dolcino, E. Cozzani, S. Riva, A. Parodi, E. Tinazzi, C. Lunardi, A. Puccetti

“…In addition, gene modulation provides evidence for a local inflammatory response (IL8, PTGFR, FSTL1, IFI16, BDKRD2, and NAMPT) with concomitant leukocyte recruitment (CCL5, ENPP2), endothelial cell activation, and neutrophil extravasation (SELL, SELE). …”
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Dihydrotanshinone I Alleviates Crystalline Silica-Induced Pulmonary Inflammation by Regulation of the Th Immune Response and Inhibition of STAT1/STAT3 by Yiting Zhang, Chao Li, Siyi Li, Yiping Lu, Sitong Du, Xinning Zeng, Xi Chen, Jie Chen

“…Occupational exposure to crystalline silica (CS) results in a persistent pulmonary inflammatory response that eventually leads to abnormal tissue repair, disability, and death. …”
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Isthmin 1 is Expressed by Progenitor-Like Cells in the Lung: Phenotypical Analysis of Isthmin 1+ Hematopoietic Stem-Like Cells in Homeostasis and during Infection by Guadalupe Rivera-Torruco, Carolina A. Martínez-Mendiola, Tania Angeles-Floriano, Gustavo Alberto Jaimes-Ortega, José Luis Maravillas-Montero, Rodolfo García-Contreras, Yolanda González, Esmeralda Juárez, Porfirio Nava, Vianney Ortiz-Navarrete, Oscar Medina-Contreras, Paula Licona-Limón, Ricardo Valle-Rios

“…The process by which blood cells are generated has been widely studied in homeostasis and during pathogen-triggered inflammatory response. Recently, murine lungs have been shown to be a significant source of hematopoietic progenitors in a process known as extramedullary hematopoiesis. …”
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Cytokines and Metabolic Patterns in Pediatric Patients with Critical Illness by George Briassoulis, Shekhar Venkataraman, Ann Thompson

“…The aim of this prospective study was to determine whether the metabolic response to stress is related to the inflammatory interleukin-6 (IL-6), 10 (IL-10), and other stress mediators' responses and to assess their relationships with different feeding patterns, nutritional markers, the severity of illness as assessed by the Multiple Organ System Failure (MOSF), the Pediatric Risk of Mortality Score (PRISM), systemic inflammatory response syndrome (SIRS), and mortality in critically ill children. …”
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Prediction of Poor Outcome Using the Urea to Albumin Ratio in Thoracic Empyema by Evgeni Dimitrov, Daniel Valchev, Georgi Minkov, Emil Enchev, Yovcho Yovtchev

“…We analyzed area under receiver operating characteristics (AUROC) curves of UAR, systemic inflammatory response syndrome (SIRS) and quick-sequential organ failure assessment (qSOFA), and compared their prognostic performance. …”
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Interleukin-18 Increases TLR4 and Mannose Receptor Expression and Modulates Cytokine Production in Human Monocytes by Luciane Alarcão Dias-Melicio, Reginaldo Keller Fernandes, Daniela Ramos Rodrigues, Marjorie Assis Golim, Angela Maria Victoriano Campos Soares

“…Taken together, these results show an important role of IL-18 on the early phase of inflammatory response by promoting the expression of some pattern recognition receptors (PRRs) that are important during the microbe recognition phase and by inducing some important cytokines such as TNF-α and IL-10.…”
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A Novel Platelet Activating Factor Receptor Antagonist Reduces Cell Infiltration and Expression of Inflammatory Mediators in Mice Exposed to Desiccating Conditions after PRK by Salomon Esquenazi, Jiucheng He, Na Li, Nicolas G. Bazan, Isi Esquenazi, Haydee E. P. Bazan

“…To study the contribution of a novel PAF receptor antagonist LAU-0901 in the modulation of the increased inflammatory response in mice exposed to dessicating conditions (DE) after PRK. …”
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Novel Role of Endogenous Catalase in Macrophage Polarization in Adipose Tissue by Ye Seul Park, Md Jamal Uddin, Lingjuan Piao, Inah Hwang, Jung Hwa Lee, Hunjoo Ha

“…Similarly, pharmacological inhibition of catalase activity using 3-aminotriazole induced the same phenotypic switch and inflammatory response in RAW264.7 macrophages. Finally, the same phenotypic switch and inflammatory responses were observed in primary bone marrow-derived macrophages from CKO mice. …”
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Gambaran Pemeriksaan Kadar SGOT, SGPT, Ureum dan Kreatinin Pasien Covid-19 dengan dan tanpa Komorbid by Rachmi Fadillah, Ellyza Nasrul, Tuty Prihandani

“…Coronavirus disease (COVID-19) causes damage through mechanisms: cytotoxic to the bile duct, liver and renal tubular epithelial cells; severe inflammatory response due to excessive pro-inflammatory cytokines (cytokine storm); tissue anoxia; and drug-induced liver and kidney damage. …”
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Exendin-4 Protects against Hyperglycemia-Induced Cardiomyocyte Pyroptosis via the AMPK-TXNIP Pathway by Hong Wei, Rui Bu, Qinghui Yang, Jing Jia, Tao Li, Qiuping Wang, Yanjun Chen

“…Accumulated evidence implicated pyroptosis as a vital contributor to the hyperglycemia-induced cardiac inflammatory response. Exendin-4, a GLP analog, promotes survival of cardiomyocytes in cardiovascular diseases, including diabetic cardiomyopathy. …”
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Research progress of femoral head necrosis in HIV-infected patients by Youhan Yang, Futao Ke, Zhengqi Pan, Liaobin Chen

“…Potential contributing factors have been identified, including systemic immune response, inflammatory response, local microenvironmental changes in the femoral head, and the unique anatomical structure of the femoral head, among others. …”
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The Effects of Neuroinflammation Induced by Typhoid Vaccine on Resting and Task‐Based Electroencephalography by Julia R Plank, Joseph CC Chen, Frederick Sundram, Nicholas Hoeh, Suresh Muthukumaraswamy, Joanne C Lin

“…The absence of significant alterations may be due to an insufficient inflammatory response. Further studies are needed to assess the feasibility of EEG as a technique for detection of neuroinflammation.…”
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Astaxanthin Inhibits Interleukin-6 Expression in Cerulein/Resistin-Stimulated Pancreatic Acinar Cells by Min Seung Kwak, Joo Weon Lim, Hyeyoung Kim

“…Obese patients with acute pancreatitis have a higher systemic inflammatory response rate. Levels of serum resistin, an adipocytokine secreted by fat tissues, increase with obesity. …”
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Administration of FTY720 during Tourniquet-Induced Limb Ischemia Reperfusion Injury Attenuates Systemic Inflammation by Anthony D. Foster, Diego Vicente, Jonathan J. Sexton, Luke Johnston, Nick Clark, Crystal Leonhardt, Eric A. Elster, Thomas A. Davis, Matthew J. Bradley

“…FTY720 treatment markedly decreased the number of peripheral blood T cells (p<0.05) resulting in a decreased systemic inflammatory response and lower serum creatinine levels and had a modest but significant effect in decreasing the transcription of injury-associated target genes in multiple end organs. …”
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