Role of transforming growth factor-β1 in down-regulating TNF production by alveolar macrophages during asbestos-induced pulmonary fibrosis by Irma Lemaire, Sophie Ouellet

“…Activation of alveolar macrophages (AM) for tumour necrosis factor production is suppressed initially during the inflammatory response to fibrogenic dusts. We investigated the mechanisms involved in TNF suppression, notably the role of other AM-derived mediators including prostaglandin E2 (PGE2), transforming growth factor-β1 (TGF-β1), and interleukin 6 (IL-6). …”
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Inflammatory Mediators and Angiogenic Factors in Choroidal Neovascularization: Pathogenetic Interactions and Therapeutic Implications by Claudio Campa, Ciro Costagliola, Carlo Incorvaia, Carl Sheridan, Francesco Semeraro, Katia De Nadai, Adolfo Sebastiani, Francesco Parmeggiani

“…However, many other molecules, distinctive of the inflammatory response, act as neovascular activators in CNV. …”
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A Simple Method for Establishing Adherent Ex Vivo Explant Cultures from Human Eye Pathologies for Use in Subsequent Calcium Imaging and Inflammatory Studies by Sofija Andjelic, Xhevat Lumi, Zoltán Veréb, Natasha Josifovska, Andrea Facskó, Marko Hawlina, Goran Petrovski

“…Furthermore, an ex vivo study model was established for measuring the inflammatory response in fvERMs and aLC-LECs upon TNFα treatment.…”
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The Role of Inflammation in the Pathogenesis of Preeclampsia by Michał Michalczyk, Aleksander Celewicz, Marta Celewicz, Paula Woźniakowska-Gondek, Rafał Rzepka

“…Some significant factors responsible for PE development include oxidative stress, abnormal concentration and activity in mononuclear phagocytic system, altered levels of angiogenic and antiangiogenic factors, and impaired inflammatory response triggered by inflammasomes. Detailed understanding of pathophysiology of inflammatory process in PE can largely contribute to new, targeted anti-inflammatory therapies that may improve perinatal outcomes in PE patients.…”
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Comparative Effects of Umbilical Cord- and Menstrual Blood-Derived MSCs in Repairing Acute Lung Injury by Haitao Ren, Qiang Zhang, Jinfu Wang, Ruolang Pan

“…Our results showed that both UCMSC and MBMSC transplantation inhibited the inflammatory response and promoted lung tissue repair. UCMSC treatment resulted in reduced damage and inflammation in the lung tissue and enhanced protection of lung function. …”
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Paediatric Inflammatory Bowel Disease: A Mechanistic Approach to Investigate Exclusive Enteral Nutrition Treatment by Lily Nahidi, Andrew S. Day, Daniel A. Lemberg, Steven T. Leach

“…Although several pharmacological approaches are used to modulate the inflammatory response in IBD, few lead to histological healing and most have side effects. …”
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Cytokine Response to Acute Endurance Exercise: Regular Treadmill Versus Lower Body Positive Pressure Treadmill by Muhammed Salih Kırışka, Nilsel Okudan, Muaz Belviranlı

“…CONCLUSIONS: Acute endurance exercise may not be sufficient to induce a significant systemic inflammatory response in physically active men.…”
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Hyperexcitability in Spinal WDR Neurons following Experimental Disc Herniation Is Associated with Upregulation of Fractalkine and Its Receptor in Nucleus Pulposus and the Dorsal Ro... by Daniel Pitz Jacobsen, Aurora Moen, Fred Haugen, Johannes Gjerstad

“…Lumbar radicular pain following intervertebral disc herniation may be associated with a local inflammatory response induced by nucleus pulposus (NP) cells. …”
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Pediatric Nasal Lobular Capillary Hemangioma by Jordan M. Virbalas, John P. Bent, Sanjay R. Parikh

“…We review the histopathology of and current epidemiological data pertaining to LCH which suggests that the development of these lesions may involve a hyperactive inflammatory response influenced by endocrine factors. We report two new cases of pediatric lobular capillary hemangioma (LCH) of the nasal cavity and review current theories regarding the etiology, diagnosis, and treatment of nasal LCH. …”
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Cannabis sativa extracts inhibit LDL oxidation and the formation of foam cells in vitro, acting as potential multi-step inhibitors of atherosclerosis development. by Bruno Musetti, Alejandra Kun, David Menchaca, Alejandra Rodríguez-Haralambides, Javier Varela, Leonor Thomson, Edward M Bahnson

“…The capacity of the extracts to prevent the oxidation of LDL, the formation of foam cells and the activation of an inflammatory response by J774 cells, were monitored by UV-Vis spectrometry, confocal-microscopy and western blot. …”
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PANoptosis in intestinal epithelium: its significance in inflammatory bowel disease and a potential novel therapeutic target for natural products by Chuanxiang Zhao, Shan Lin

“…Consequently, excessive IEC death advances intestinal permeability and as a consequence thereof the translocation of bacteria into the lamina propria, subsequently triggering an inflammatory response, which underpins the clinical disease trajectory of inflammatory bowel disease (IBD). …”
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M2-like macrophage-derived exosomes inhibit osteoclastogenesis via releasing miR-1227-5p by Shan Chen, Jian Liu, Lilei Zhu

“…Macrophages play a pivotal role in regulating inflammatory response in periodontitis, a condition characterized by excessive osteoclast differentiation. …”
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Psoas abscess secondary to atypical appendicitis in pregnancy. A case report by Viviana de la Caridad Sáez Cantero, Mario Joel Arroyo Díaz, Leonel Hernández Torres, María Teresa Medel Agüero

“…The psoas abscess is a rare infectious disease that is difficult to diagnose, characterized by a purulent collection at the level of this muscle, which causes a systemic inflammatory response syndrome. The infection can be primary by hematogenous dissemination, or secondary, from a nearby infectious focus. …”
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The Correlation between Chronic Periodontitis and Oral Cancer by Maximilian Krüger, Torsten Hansen, Adrian Kasaj, Maximilian Moergel

“…Furthermore, the inflammatory response has the potential to activate carcinogenesis. …”
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Issues occult hepatitis B virus infection by I. A. Morozov, L. Yu. Ilchenko, N. I. Gromova, I. G. Fyedorov, I. V. Gordeychuk, A. K. Knyazhentseva, E. V. Zverkova, M. I. Mikhaylov

“…HBV and HCV coinfection was accompanied by more severe (in comparison to monoinfection) immune inflammatory response. In 80% of cases presence of TT-like mini virus (TTMV) in blood lymphoid elements was revealed, in two patients this virus was detected in hepatocyte nucleus that proves its hepatotropic properties.Conclusions. …”
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Asthma in Sickle Cell Disease by Manisha Newaskar, Karen A. Hardy, Claudia R. Morris

“…It is known that SCD is associated with a proinflammatory state and an enhanced inflammatory response is seen during vaso-occlusive events (VOE). …”
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Proteomic Analysis of Exudates from Chronic Ulcer of Diabetic Foot Treated with Scorpion Antimicrobial Peptide by Zhixiang Tan, Zhiguo Yu, Xiaobo Xu, Lanxia Meng, Mosheng Yu, Rui Tao, Yingliang Wu, Zhanyong Zhu

“…Inhibited biological functions such as cell death, inflammatory response, immune diseases, and bacterial growth were also involved. …”
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Oleuropein Improves Cognitive Dysfunction and Neuroinflammation in Diabetic Rats through the PI3K/Akt/mTOR Pathway by Jianru Shang, Shan Che, Mingjie Zhu

“…It also could improve oxidative stress and inflammatory response and activate the PI3K/Akt/mTOR signaling pathway in hippocampus tissues. …”
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Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft by Andreas O. Parashis, Charalampos J. Kalaitzakis, Dimitris N. Tatakis, Konstantinos Tosios

“…Histological and immunohistochemical analysis from 9 sites (4 patients) indicated normal mucosa with complete incorporation of the matrix and absence of inflammatory response. The XCM + FDBA combination resulted in minimal complications and desirable soft and hard tissue therapeutic outcomes, suggesting the feasibility of this approach for ARP.…”
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Picolinic Acid in Patients with Chronic Hepatitis C Infection: A Preliminary Report by Jolanta Zuwała-Jagiello, Monika Pazgan-Simon, Krzysztof Simon, Maria Warwas

“…We documented that significant elevation in serum PA levels is associated with diabetes prevalence and increased inflammatory response reflected in hsCRP levels in CHC patients.…”
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