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441
Role of Helicobacter pylori in the Pathogenesis of Gastric Carcinoma and Progression of Lymphoid Nodules to Lymphoma
Published 1999-01-01“…The potential mechanisms of gastric carcinogenesis include transformation of the gastric mucosa by metabolic products of H pylori, transformation of the host cell by incorporation of H pylori DNA and genotoxic effects of the inflammatory response to the organism. A model for gastric carcinogenesis is proposed in which H pylori causes cell proliferation, and the risk of DNA damage is increased, leading to inadequate repair and malignant transformation. …”
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442
Extreme Procalcitonin Elevation without Proven Bacterial Infection Related to Amphetamine Abuse
Published 2014-01-01“…Systemic inflammatory response with rhabdomyolysis and consequent multiorgan failure is a known sequela of psychotropic drug abuse. …”
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443
TNIP1 in Autoimmune Diseases: Regulation of Toll-like Receptor Signaling
Published 2018-01-01“…TNIP1 dysfunction or deficiency may predispose healthy cells to the inflammatory response to otherwise innocuous TLR ligand exposure. …”
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444
Cytokines and Myelination in the Central Nervous System
Published 2008-01-01“…Many cytokines are virtually undetectable in the uninflamed central nervous system (CNS), so that their rapid induction and sustained elevation in immune and glial cells contributes to dysregulation of the inflammatory response and neural cell homeostasis. This results in aberrant neural cell development, cytotoxicity, and loss of the primary myelin-producing cells of the CNS, the oligodendrocytes. …”
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445
NF-κB Inhibitory Activity of the Di-Hydroxy Derivative of Piperlongumine (PL-18)
Published 2025-01-01“…We found that piperlongumine (PL)-18, a di-hydroxy derivative of PL from long pepper, inhibits the nuclear factor kappa B (NF-kB), a master transcription factor of numerous components of the inflammatory response. NF-kB was inhibited by PL-18 in two human cell-lines, L428 and A549, by preventing the nuclear translocation of p65 NF-kB. …”
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446
Submucosal esophageal abscess evolved from a peritonsillar abscess diagnosed using esophagogastroduodenoscopy and endoscopic ultrasonography: A case report
Published 2025-12-01“…Her abscess spontaneously drained, and blood tests showed improved inflammatory response, indicated by the white blood cell count and C-reactive protein concentration. …”
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447
Modulation of local immunity by the vaginal microbiome is associated with triggering spontaneous preterm birth
Published 2024-11-01“…Microbial functional analysis identified 31 distinct functional pathways, six of which were downregulated in the preterm birth and excessive inflammatory response group. Significant differences in vaginal microbial diversity and composition were observed among pregnant women with different immune subtypes. …”
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448
Warm and humid environment induces gut microbiota dysbiosis and bacterial translocation leading to inflammatory state and promotes proliferation and biofilm formation of certain ba...
Published 2025-01-01“…In the model group, fungal translocation was observed, potentially triggering an inflammatory response. Intraperitoneal injections of various bacterial strains in mice reproduced the sticky stool characteristics. …”
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449
Effect of Hemoadsorption for Cytokine Removal in Pneumococcal and Meningococcal Sepsis
Published 2018-01-01“…Both conditions are characterized by an impressive inflammatory response, resulting rapidly in cerebral edema, infarction, hydrocephalus, and septic shock with multiple organ failure. …”
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450
The spatiotemporal and paradoxical roles of NRF2 in renal toxicity and kidney diseases
Published 2025-02-01“…These changes are directly or indirectly connected to altered antioxidant defense, damage repair, inflammatory response, regulated cell death and fibrogenesis, culminating ultimately in either protective or deleterious outcomes. …”
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451
Selected Mechanisms of Action of Bacteriophages in Bacterial Infections in Animals
Published 2025-01-01“…They can therefore have a profound impact on the course of bacterial infections by stimulating and at the same time inhibiting the systemic pro-inflammatory response. This review article presents a characterization of the processes by which bacteriophages affect selected immune mechanisms in selected animal species. …”
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452
Delirium Accompanied by Cholinergic Deficiency and Organ Failure in a 73-Year-Old Critically Ill Patient: Physostigmine as a Therapeutic Option
Published 2015-01-01“…., heart and kidneys) and the inflammatory response too. This perception might explain that delirium is not an individual symptom, but rather a part of a symptom complex with various disorders of the whole organism. …”
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453
Evaluation of the biocompatibility of various self-adhesive resin cements on subcutaneous connective tissue: An in vivo study
Published 2023-08-01“…High Q Bond and Zirconite exhibited satisfactory biocompatibility; however, Panavia demonstrated a moderate inflammatory response at 90 days.…”
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454
Type 2 Diabetes, PUFAs, and Vitamin D: Their Relation to Inflammation
Published 2014-01-01“…In conclusion, certain fatty acids in the adequate proportion as well as 25-hydroxivitamin D can modulate the inflammatory response in diabetic people, modifying the evolution of this disease.…”
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455
Therapeutic Applicability of Anti-Inflammatory and Proresolving Polyunsaturated Fatty Acid-Derived Lipid Mediators
Published 2010-01-01“…The enzymatic oxygenation of polyunsaturated fatty acids by lipoxygenases and cyclo-oxygenases is a resourceful mode of formation of specific autacoids that regulate the extent and pace of the inflammatory response. Arachidonate-derived eicosanoids, such as lipoxin A4, prostaglandin (PG)D2, PGF2α, PGE2, and PGD2-derived cyclopentenones exert specific roles in counter-regulating inflammation and turning on resolution. …”
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456
Mast Cell Activation Syndrome in COVID-19 and Female Reproductive Function: Theoretical Background vs. Accumulating Clinical Evidence
Published 2022-01-01“…The multisystem inflammatory response in COVID-19 shows many analogies with mast cell activation syndrome (MCAS), and MCAS may be an important component in the course of COVID-19. …”
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457
The Pathophysiological Relationship Between Migraine and SARS-CoV-2 Infection: A Comprehensive Literature Review
Published 2022-12-01“…COVID-19 causes an increase in nod-like receptor protein 3, which causes the production of IL-1β and again induces an inflammatory response. This review article looks at the mechanisms of migraine and COVID-19, and tries to link a common pathophysiological pathway between the two. …”
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458
Identification of hub genes and pathogenesis in Kawasaki disease based on bioinformatics analysis
Published 2024-04-01“…Conclusions: These 13 key genes may mediate the occurrence and development of KD through various processes such as immune regulation, inflammatory response, glucose metabolism, autophagy, and apoptosis, which provide valuable references for the diagnosis and treatment of KD.…”
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459
Recent Advances in Pathogenesis and Anticoagulation Treatment of Sepsis-Induced Coagulopathy
Published 2025-01-01“…Although immunothrombosis is necessary for infection control, excessive thrombus formation can trigger a systemic thrombo-inflammatory response. Immunothrombosis plays a core role in sepsis-induced coagulopathy, and research has revealed a complex interplay between inflammation and coagulation. …”
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460
Calotropis procera Latex-Induced Inflammatory Hyperalgesia—Effect of Antiinflammatory Drugs
Published 2005-01-01“…In the present study we have evaluated the antiedematous and analgesic activity of antiinflammatory drugs against inflammatory response induced by dried latex (DL) of C procera in rat paw edema model. …”
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