Nerve Blockage Attenuates Postoperative Inflammation in Hippocampus of Young Rat Model with Surgical Trauma by Yi He, Zhi Li, Yun-Xia Zuo

“…The potential inhibitory effect of nerve blockage with local anesthetics on peripheral inflammatory response has been reported. We hypothesize that nerve blockage may be effective in reducing postoperative inflammation and cognitive decline. …”
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The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment by Yi-Cheng Chang, Siow-Wey Hee, Meng-Lun Hsieh, Yung-Ming Jeng, Lee-Ming Chuang

“…Specifically, excessive nutrients trigger endoplasmic reticulum stress and increase the production of mitochondrial reactive oxygen species, leading to activation of stress signaling pathway, inflammatory response, lipogenesis, and pancreatic beta-cell death. …”
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Helicobacter pylori and T Helper Cells: Mechanisms of Immune Escape and Tolerance by Tiziana Larussa, Isabella Leone, Evelina Suraci, Maria Imeneo, Francesco Luzza

“…H. pylori-driven interactions with the host immune system underlie the persistence of the infection in humans, since the bacterium is able to interfere with the activity of innate and adaptive immune cells, reducing the inflammatory response in its favour. Gastritis due to H. pylori results from a complex interaction between several T cell subsets. …”
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Immunobiotics Beneficially Modulate TLR4 Signaling Triggered by Lipopolysaccharide and Reduce Hepatic Steatosis In Vitro by Paulraj Kanmani, AbuZar Ansari, Julio Villena, Hojun Kim

“…These results demonstrated that immunobiotics exhibit potent immunoregulatory activity and may be used as effective therapeutic agents to alleviate inflammatory response.…”
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Blood Flukes and Arterial Damage: A Review of Aneurysm Cases in Patients with Schistosomiasis by Valeria Silvestri, Vivian Mushi, Mwanahawa Idavas Mshana, Witness M. Bonaventura, Nyanda C. Justine, Deodatus Sabas, Billy Ngasala

“…Schistosomiasis, caused by trematode worms of the genus Schistosoma, has organ-specific morbidity due to host’s inflammatory response to the oviposition of parasite eggs in vessels and organs. …”
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LPA Promotes T Cell Recruitment through Synthesis of CXCL13 by Weili Hui, Chenqi Zhao, Sylvain G. Bourgoin

“…Our data highlight that LPA-mediated CXCL13 secretion plays a role in T cell recruitment and participates in regulation of the inflammatory response.…”
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RNA Viruses: ROS-Mediated Cell Death by Mohammad Latif Reshi, Yi-Che Su, Jiann-Ruey Hong

“…Oxidative stress via RNA virus infections can contribute to several aspects of viral disease pathogenesis including apoptosis, loss of immune function, viral replication, inflammatory response, and loss of body weight. We focus on how ROS production is correlated with host cell death. …”
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Mechanisms of Bone Resorption in Periodontitis by Stefan A. Hienz, Sweta Paliwal, Saso Ivanovski

“…Bone destruction is mediated by the host immune and inflammatory response to the microbial challenge. However, the mechanisms by which the local immune response against periodontopathic bacteria disturbs the homeostatic balance of bone formation and resorption in favour of bone loss remain to be established. …”
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Role of PPARs in Trypanosoma cruzi Infection: Implications for Chagas Disease Therapy by Eugenia Hovsepian, Federico Penas, Gerardo A. Mirkin, Nora B. Goren

“…T. cruzi infection causes an intense inflammatory response in diverse tissues by triggering local expression of inflammatory mediators, which results in the upregulation of the levels of cytokines and chemokines, and important cardiac alterations in the host, being one of the most characteristic damages of Chagas disease. …”
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Differential Role of Adipose Tissues in Obesity and Related Metabolic and Vascular Complications by Almudena Gómez-Hernández, Nuria Beneit, Sabela Díaz-Castroverde, Óscar Escribano

“…Weight gain in obesity generates excess of fat, usually visceral fat, and activates the inflammatory response in the adipocytes and then in other tissues such as liver. …”
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Microangiopathic Hemolytic Anemia: A Rare Complication of Acute Pancreatitis by Syedda Ayesha, Masood Muhammad Karim, Maria Ali, Abdul Hadi Shahid, Salman Naseem Adil

“…Though uncommon, MAHA can occur as a complication of acute pancreatitis because of the associated inflammatory response. Patients with MAHA secondary to pancreatitis show favorable outcomes when treated with plasma exchange. …”
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Sirtuin 1 and Aging Theory for Chronic Obstructive Pulmonary Disease by V. Conti, G. Corbi, V. Manzo, G. Pelaia, A. Filippelli, A. Vatrella

“…Processes including oxidant/antioxidant, protease/antiprotease, and proliferative/antiproliferative balance and control of inflammatory response become dysfunctional during aging as well as in COPD. …”
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No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients by Leszek Tylicki, Bogdan Biedunkiewicz, Dominik Rachon, Tomasz Nieweglowski, Lukasz Hak, Andrzej Chamienia, Alicja Debska-Slizien, Ewa Aleksandrowicz, Jolanta Mysliwska, Boleslaw Rutkowski

“…BACKGROUND: Ozone as a strong oxidant may induce an inflammatory response.…”
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Whipple’s Disease-Associated Pulmonary Hypertension with Positive Vasodilator Response Despite Severe Hemodynamic Derangements by Salah Najm, Joud Hajjar, Robert P Nelson, Ramana S Moorthy, Karen M Wolf, Tim Lahm

“…Furthermore, the case highlights the phenomenon of PH in the setting of inflammation, suggesting that adequate control of the inflammatory response can be accompanied by a marked improvement in hemodynamics in certain types of PH.…”
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Treatment with the CCR5 antagonist OB-002 reduces lung pathology, but does not prevent disease in a Syrian hamster model of SARS-CoV-2 infection. by Bryce M Warner, Robert Vendramelli, Amrit S Boese, Jonathan Audet, Nikesh Tailor, Courtney Meilleur, Nathan Glowach, Marnie Willman, Thang Truong, Estella Moffat, Kevin Tierney, Beata Kosak, Irfan Dhanidina, Jarret Engstrom, Bozena Korczak, Ian McGowan, Carissa Embury-Hyatt, Darwyn Kobasa

“…Immunomodulatory drugs have shown success in dampening the deleterious inflammatory response seen in severe COVID-19 patients, but there remains an urgent need for development of additional therapeutic options for COVID-19 treatment. …”
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Serum IL-18 Is Increased at Early Postburn Period in Moderately Burned Patients by Y. Kenan Coban, Murat Aral

“…A severe systemic inflammatory response is usually seen after burn injury. …”
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The Effects of Dipeptidyl Peptidase-4 Inhibitors on Cardiovascular Disease Risks in Type 2 Diabetes Mellitus by Pegah Yousefzadeh, Xiangbing Wang

“…These agents may have the potential to lower blood pressure, improve lipid profile and endothelial dysfunction, decrease the macrophage-mediated inflammatory response, and prevent myocardial injury. Conclusion. …”
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Interleukin-6 “Trans-Signaling” and Ischemic Vascular Disease: The Important Role of Soluble gp130 by Mario Luca Morieri, Angelina Passaro, Giovanni Zuliani

“…Interleukine-6 (IL-6) is a multifunctional cytokine involved both in the beneficial acute inflammatory response and in the detrimental chronic low-grade systemic inflammation. …”
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Inhibition of Immune Complex-Induced Inflammation by A small Molecular Weight Selectin Antagonist by X. Nair, G. Todderud, L. Davern, D. Lee, A. Aruffo, K. M. Tramposch

“…The rat dermal reverse passive Arthus reaction was used to assess the effect of sulphatide on a neutrophil dependent inflammatory response. Sulphatide dosedependently blocked both the vascular permeability increase and cell infiltration after intraperitoneal administration. …”
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COSMC-Regulated O-Glycosylation: A Bioinformatics-Driven Biomarker Identification for Stratifying Glioblastoma Stem Cell Subtypes by Sara Sadat Aghamiri, Rada Amin

“…High Cosmc expression also enriched immune-related pathways, including inflammatory response and antigen presentation, and was associated with presence of myeloid cells, T cells, and NK cells. …”
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