Clinical, histopathological and parasitological follow-up of dogs naturally infected by Leishmania infantum before and after miltefosine treatment and associated therapies. by Amábilli de Souza Rosar, Carolina Leite Martins, Álvaro Menin, Carolina Reck, Edmundo Carlos Grisard, Glauber Wagner, Mário Steindel, Patricia Hermes Stoco, Patricia Flavia Quaresma

“…Skin biopsies were obtained from the abdomen to assess inflammatory responses and to quantify parasite loads using qPCR. …”
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Annexin A5 knockdown inhibits cardiomyocyte apoptosis and alleviates cardiac hypertrophy via activating the PI3K/AKT/Bcl-2 signaling pathway by Lina Zhao, Hongjuan Cao, Yao Yuan, Chunyan Liao, Dan Huang, Xiaoyi Li, Yueyao Zhao, Quanfeng Huang, Sha Li, Bei Zhang

“…The expression of ANXA5 protein and mRNA was overexpressed, and knockdown of ANXA5 can effectively attenuate cardiomyocyte apoptosis and inflammatory response, ameliorate myocardial hypertrophy and cardiac dysfunction in ALD-induced hypertrophic cardiomyocytes and in SHR hypertrophic hearts. …”
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Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children by Abdulaziz Alolayan, Abdullah S. Aldamegh, Azzah Alkhayrat

“…Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist used to suppress the exaggerated inflammatory response in such conditions, and it is potentially lifesaving in a cytokine storm. …”
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From micro to macro, nanotechnology demystifies acute pancreatitis: a new generation of treatment options emerges by Wei Du, Xinyue Wang, Yuyan Zhou, Wencheng Wu, Haojie Huang, Zhendong Jin

“…Abstract Acute pancreatitis (AP) is a disease characterized by an acute inflammatory response in the pancreas. This is caused by the abnormal activation of pancreatic enzymes by a variety of etiologic factors, which results in a localized inflammatory response. …”
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Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis by M. Isabel García-Laorden, Ingrid Stroo, Sanne Terpstra, Sandrine Florquin, Jan Paul Medema, Cornelis van´t Veer, Alex F. de Vos, Tom van der Poll

“…These results suggest that gzms influence bacterial growth and the host inflammatory response during abdominal sepsis caused by E. coli.…”
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Proinflammatory Responses of Heme in Alveolar Macrophages: Repercussion in Lung Hemorrhagic Episodes by Rafael L. Simões, Maria Augusta Arruda, Cláudio Canetti, Carlos H. Serezani, Iolanda M. Fierro, Christina Barja-Fidalgo

“…Taken together, the data support a dual role for heme in the inflammatory response associated with lung hemorrhage, acting as a proinflammatory molecule that can either act as both an adjuvant of the innate immunity and as an amplifier of the inflammatory response, leading tissue injury. …”
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lncRNA IGHCγ1 Acts as a ceRNA to Regulate Macrophage Inflammation via the miR-6891-3p/TLR4 Axis in Osteoarthritis by Pengjun Zhang, Jianmei Sun, Caihong Liang, Bingjie Gu, Yang Xu, Hongying Lu, Bo Cao, Hao Xu

“…This study strongly supports that lncRNA IGHCγ1 regulates inflammatory response via regulating the miR-6891-3p/TLR4/NF-κB axis in macrophages.…”
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Role of Cholinergic Anti-Inflammatory Pathway in Protecting Sepsis-Induced Acute Lung Injury through Regulation of the Conventional Dendritic Cells by Ruiting Li, Xuemei Hu, Huibin Chen, Yue Zhao, Xuehui Gao, Yin Yuan, Huiling Guo, Haiyan Huang, Xiaojing Zou, Hong Qi, Hong Liu, You Shang

“…It was hypothesized that cholinergic anti-inflammatory pathway may inhibit the inflammatory response of ALI by regulating maturation, phenotype, and quantity of DCs and conventional DCs. …”
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Physalis Calyx seu Fructus relieves chicken intestinal damage to heat via improving the antioxidant ability by Bin Yin, Changning Juan, Rongling Zhang, Shifa Yang, Haiting Wang, Yueyue Liu, Shikai Song, Zunxiang Yan, Yunpeng Yi, Zengcheng Zhao, Zhongli Huang, Shuqian Lin

“…Heat-stress-induced oxidative and inflammatory responses were important factors contributing to chicken intestinal damage. …”
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Explore Alteration of Lung and Gut Microbiota in a Murine Model of OVA-Induced Asthma Treated by CpG Oligodeoxynucleotides by Wang Q, Ji J, Xiao S, Wang J, Yan X, Fang L

“…High-throughput sequencing technology targeting 16S rRNA was employed to analyze the composition, diversity, and correlation of microbiome in the lung, colon and small intestine of control, model and CpG-ODN administration groups.Results: (1) Histopathologically, both lung and intestinal tissue in asthmatic mice exhibited significant structural damage and inflammatory response, whereas the structure of both lung and intestinal tissue approached normal levels, accompanied by a notable improvement in the inflammatory response after CpG-ODN treatment. (2) In the specific microbiota composition analysis, bacterial dysbiosis observed in the asthmatic mice, accompanied by enrichment of Proteobacteria found to cause lung and intestinal epithelial damage and inflammatory reaction. …”
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The effect of cacao bean extracts on the prevention of periodontal tissue breakdown in diabetic rats with orthodontic tooth movements by Nuzulul Hikmah, Mohamad Hidayat, Nur Permatasari, Aulanni'am Aulanni'am, Achmad Rudijanto

“…Cacao bean extracts (CBE) are known to reduce the inflammatory response and increase synthesis and angiogenesis in periodontitis. …”
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Neonatal Sepsis and Inflammatory Mediators by Juliana Reis Machado, Danilo Figueiredo Soave, Marcos Vinícius da Silva, Liliana Borges de Menezes, Renata Margarida Etchebehere, Maria Luiza Gonçalves dos Reis Monteiro, Marlene Antônia dos Reis, Rosana Rosa Miranda Corrêa, Mara Rúbia Nunes Celes

“…Sepsis is the result of an infection associated with a systemic inflammatory response with production and release of a wide range of inflammatory mediators. …”
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Cytokines in Thyroid-Associated Ophthalmopathy by Pengbo Zhang, Huang Zhu

“…The pathogenesis of TAO has not been fully elucidated, and the mainstream view is that coantigens shared by the thyroid and orbit trigger remodeling of extraocular muscles and orbital connective tissues through an inflammatory response. In recent years, cytokines and the immune responses they mediate have been crucial in disease progression, and currently, common evidence has shown that drugs targeting cytokines, such as tocilizumab, infliximab, and adalimumab, may be novel targets for therapy. …”
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Inflammation as a Driver of Clonal Evolution in Myeloproliferative Neoplasm by Angela G. Fleischman

“…The impact of chronic inflammation, a characteristic feature of MPN, likely goes far beyond its role as a driver of constitutional symptoms. An inflammatory response to the neoplastic clone may be responsible for some pathologic aspects of MPN. …”
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Cromolyn sodium reduces LPS-induced pulmonary fibrosis by inhibiting the EMT process enhanced by MC-derived IL-13 by Cheng Tan, Hang Zhou, Qiangfei Xiong, Xian Xian, Qiyuan Liu, Zexin Zhang, Jingjing Xu, Hao Yao

“…Abstract Background Sepsis is a systemic inflammatory response caused by infection. When this inflammatory response spreads to the lungs, it can lead to acute lung injury (ALI) or more severe acute respiratory distress syndrome (ARDS). …”
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Alcohol promotes CPT1A-induced lipid metabolism disorder to sentinel-regulate acute pancreatitis by Zenghui Li, Xinghui Li, Hui Jiang, Jingdong Li, Bin Xiao, Yong Chen, Shunhai Jian, Mei Zeng, Xiaoming Zhang

“…Etomoxir injection reduced the inflammatory response in the AAP rat model. Conclusion Alcohol upregulates CPT1A protein expression in pancreatic tissue, resulting in abnormal lipid metabolism. …”
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Aspergillus fumigatus is responsible for inflammation in a murine model of chronic obstructive pulmonary disease exacerbation by Alexandra Bouyssi, Alexis Trecourt, Tanguy Déméautis, Florence Persat, Olivier Glehen, Martine Wallon, Gilles Devouassoux, Abderrazzak Bentaher, Jean Menotti

“…Conclusions There was a stronger inflammatory response after cigarette smoke exposure with A. fumigatus compared to cigarette smoke alone. …”
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Changes in Peripheral Blood Neutrophils, Lymphocytes and IL-10 in Children with Kawasaki Disease from Different Age Groups Undergoing Intravenous Immunoglobulin: A Retrospective St... by Chun Zhang, Xuan Zhang, Jia Shen, Xiaotong Lu, Jian Zhang, Sun Chen

“…However, the patients’ inflammatory response during usage remains unclear. In the present study, the association between inflammatory response and lymphocyte count in children with KD from different ages was evaluated before and after IVIG. …”
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Halofuginone prevents inflammation and proliferation of high-altitude pulmonary hypertension by inhibiting the TGF-β1/Smad signaling pathway by Jiangtao Wang, Lina Guan, Jian Yu, Bohua Ma, Huihua Shen, Guozhu Xing, Yawei Xu, Qiufang Li, Juan Liu, Qin Xu, Wenhui Shi, Jia He, Yixuan Huang, Dongfeng Yin, Wu Li, Rui Wang

“…Abstract The inflammatory response of lung tissue and abnormal proliferation of pulmonary artery smooth muscle cells are involved in the pathogenesis of high-altitude pulmonary hypertension (HAPH). …”
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The Microbiota Determines Susceptibility to Experimental Autoimmune Uveoretinitis by Jarmila Heissigerova, Petra Seidler Stangova, Aneta Klimova, Petra Svozilkova, Tomas Hrncir, Renata Stepankova, Miloslav Kverka, Helena Tlaskalova-Hogenova, John V. Forrester

“…Here, we evaluated how its absence or reduction modifies the inflammatory response in the murine model of experimental autoimmune uveoretinitis (EAU). …”
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