Danger Signals Activating the Immune Response after Trauma by Stefanie Hirsiger, Hans-Peter Simmen, Clément M. L. Werner, Guido A. Wanner, Daniel Rittirsch

“…Sterile injury can cause a systemic inflammatory response syndrome (SIRS) that resembles the host response during sepsis. …”
Get full text

Using nonlinear model predictive control to find optimal therapeutic strategies to modulate inflammation by Judy Day, Jonathan Rubin, Gilles Clermont

“…Modulation of the inflammatory response has become a key focal point in the treatment of critically ill patients. …”
Get full text

The Rise of Pluripotent Stem Cell-Derived Glia Models of Neuroinflammation by Srishti Kala, Andrew G. Strutz, Moriah E. Katt

“…Neuroinflammation is a blanket term that describes the body’s complex inflammatory response in the central nervous system (CNS). …”
Get full text

Changes in Intestinal Microbiota Are Associated with Islet Function in a Mouse Model of Dietary Vitamin A Deficiency by Yunting Zhou, Junming Zhou, Yumin Zhang, Jun Tang, Bo Sun, Wei Xu, Xiaohang Wang, Yang Chen, Zilin Sun

“…The intestinal morphology, intestinal permeability, and inflammatory response activation signaling pathway were assessed using histological staining, western blots, quantitative-PCR, and enzyme-linked immunosorbent assays. …”
Get full text

Dried Human Amniotic Membrane Does Not Alleviate Inflammation and Fibrosis in Experimental Strabismus Surgery by Bo Young Chun, Hong Kyun Kim, Jae Pil Shin

“…The purpose of this study was to evaluate the efficacy of dried human amniotic membrane (AM) in reducing the postoperative inflammatory response and scarring after strabismus surgery. …”
Get full text

DAMPs Synergize with Cytokines or Fibronectin Fragment on Inducing Chondrolysis but Lose Effect When Acting Alone by Lei Ding, Joseph A. Buckwalter, James A. Martin

“…MTDs or HMGB1 could only stimulate inflammatory response in chondrocytes with the presence of cytokines or Fn-f.…”
Get full text

Role of Lysosomes in Silica-Induced Inflammasome Activation and Inflammation in Absence of MARCO by Rupa Biswas, Raymond F. Hamilton, Andrij Holian

“…Previously, it was shown that mice null for MARCO have a greater inflammatory response to silica, but the mechanism was not described. …”
Get full text

Nuclear Alarmin Cytokines in Inflammation by Lili Jiang, Yijia Shao, Yao Tian, Changsheng Ouyang, Xiaohua Wang

“…Pathogen-associated molecular patterns (PAMPs) are some nonspecific and highly conserved molecular structures of exogenous specific microbial pathogens, whose products can be recognized by pattern recognition receptor (PRR) on innate immune cells and induce an inflammatory response. Under physiological stress, activated or damaged cells might release some endogenous proteins that can also bind to PRR and cause a harmful aseptic inflammatory response. …”
Get full text

Nanoporosity of Alumina Surfaces Induces Different Patterns of Activation in Adhering Monocytes/Macrophages by Natalia Ferraz, Jaan Hong, Matteo Santin, Marjam Karlsson Ott

“…The data of this paper implies that nanotopography could be exploited for controlling the inflammatory response to implants.…”
Get full text

Dexmedetomidine Mitigates Microglial Activation Associated with Postoperative Cognitive Dysfunction by Modulating the MicroRNA-103a-3p/VAMP1 Axis by Zhichao Wu, Han Wang, Zuan Shi, Yalan Li

“…We found that lipopolysaccharide (LPS) induced substantial inflammatory responses in primary and BV2 microglial cells. …”
Get full text

The Consequences of Chorioamnionitis: Preterm Birth and Effects on Development by Robert Galinsky, Graeme R. Polglase, Stuart B. Hooper, M. Jane Black, Timothy J. M. Moss

“…Chorioamnionitis is often associated with a fetal inflammatory response. The fetal inflammatory response syndrome (FIRS) is defined by increased systemic inflammatory cytokine concentrations, funisitis, and fetal vasculitis. …”
Get full text

Marine Diterpenoids as Potential Anti-Inflammatory Agents by Yisett González, Daniel Torres-Mendoza, Gillian E. Jones, Patricia L. Fernandez

“…The inflammatory response is a highly regulated process, and its dysregulation can lead to the establishment of chronic inflammation and, in some cases, to death. …”
Get full text

Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Attenuates Aldosterone-Infused Renal Injury by Honglei Guo, Hongmei Li, Lilu Ling, Yong Gu, Wei Ding

“…The effect of TUDCA on the Aldo-infused inflammatory response and renal injury was investigated using periodic acid-Schiff staining, real-time PCR, Western blot, and ELISA. …”
Get full text

Visfatin Amplifies Cardiac Inflammation and Aggravates Cardiac Injury via the NF-κB p65 Signaling Pathway in LPS-Treated Mice by Yewen Hu, Nan Wu, Weiping Du, Shuangshuang Wang, Jian Wang, Chaoxia Zhang, Xiaomin Chen, Caijie Shen

“…This study showed that visfatin amplifies the cardiac inflammatory response and aggravates cardiac injury through the p65 signaling pathway. …”
Get full text

Acute inflammatory profile of patients submitted to pulmonary resection by Andrea Pelicia Roso de Souza, Raquel Palhares, Letícia Baltieri, Ricardo Kalaf Mussi, Edson Antunes, Glaucia Coelho de Mello

“…ABSTRACT Purpose: To establish a profile of the inflammatory response in the preoperative and postoperative period of pulmonary resection of patients without postoperative complications, in order to trace the inflammatory profile of lung resection surgery. …”
Get full text

Prenatal exposure to bisphenol A causes reproductive damage in F1 male rabbits due to inflammation and oxidative stress by Qianhui Zhao, Jialu Pan, Yongzhan Bao, Xiao Wang, Wanyu Shi

“…The results indicated that BPA exposure triggered an inflammatory response and oxidative stress, consequently impacting the reproductive system of weaned rabbits and altering reproductive hormone levels. …”
Get full text

The Roles of FOXO1 in Periodontal Homeostasis and Disease by Liang Ren, Jing Yang, Jun Wang, Xuedong Zhou, Chengcheng Liu

“…Dysbiotic immune-inflammatory response and bone remodeling are characteristics of periodontitis. …”
Get full text

The Macrophage Inflammatory Proteins MIP1α (CCL3) and MIP2α (CXCL2) in Implant-Associated Osteomyelitis: Linking Inflammation to Bone Degradation by Ulrike Dapunt, Susanne Maurer, Thomas Giese, Matthias Martin Gaida, Gertrud Maria Hänsch

“…Bacterial biofilms elicit a progressive local inflammatory response, resulting in tissue damage and bone degradation. …”
Get full text

Efek Suplementasi Selenium terhadap Marker Darah Pasca Cedera Kontusio by Mariel Daba, Hanna Goenawan, Vita Murniati Tarawan, Aziis Mardanarian Rosdianto, Ronny Lesmana

“…In certain circumstances, such as injury, selenium supplementation is required to regulate the inflammatory response. Contusion injury increases the inflammatory response to a muscle or tissue that begins with vasodilation, increases blood flow, increases vascular permeability, and leads to edema formation at the site of injury. …”
Get full text

Fungal-Host Interaction: Curcumin Modulates Proteolytic Enzyme Activity of Candida albicans and Inflammatory Host Response In Vitro by Emily Chen, Bruna Benso, Dalia Seleem, Luiz Eduardo Nunes Ferreira, Silvana Pasetto, Vanessa Pardi, Ramiro Mendonça Murata

“…Furthermore, gene expressions of host inflammatory response, IL-1β and IL-1α, were significantly downregulated after exposure to curcumin. …”
Get full text