Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes by Xiu Zhang, Shengbang Wang, Wei Wang, Liumei Song, Shuo Feng, Jingping Wang, Tong Kang, Peiwen Yang, Ning Wang, Pengju Yang, Ruimin Bai, Yongping Shao, Yan Zheng

“…Extracellular cold-inducible RNA-binding protein (eCIRP) has been shown to play a role in various acute and chronic inflammatory diseases. C23, a short peptide derived from CIRP, competitively binds CIRP receptors and reduces damage in inflammatory diseases. …”
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Omega-3 long chain fatty acids and their metabolites in pregnancy outcomes for the modulation of maternal inflammatory- associated causes of preterm delivery, chorioamnionitis and... by Jose Miguel Rizo, Theresa Steeb, Johanna Eiblwieser, Pedro Antonio Regidor

“…In this way, acute and chronic inflammatory diseases associated with serious obstetrical complications can be modulated, which might contribute to an improved pregnancy outcome.…”
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Endometriosis Associated with Periodontal Disease: Two Case Reports by Shahad Mohammed Halawani, Salah Nasser Alokaili, Alhassan Mohammed Ajeebi, Pradeep Koppolu

“…Both are defined by chronic inflammatory diseases linked to a compromised immune response. …”
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Colon Lipoma Causing Colo-Colic Intussusception in an Adult: A Case Report from Tanzania by Jamil Suleiman, Mujaheed Suleman, Alex Mremi, Adnan Sadiq, Abbas Mohamedali, Dennis Machaku, Jay Lodhia

“…Causes of intussusception in adults are commonly due to tumors and inflammatory diseases. Intussusception in adults accounts for less than 5% of intestinal obstruction. …”
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Implication of IL-17 in Bone Loss and Structural Damage in Inflammatory Rheumatic Diseases by Benoit Le Goff, Béatrice Bouvard, Thierry Lequerre, Eric Lespessailles, Hubert Marotte, Yves-Marie Pers, Bernard Cortet

“…Proinflammatory cytokines play an important role in the systemic and focal bone loss associated with chronic inflammatory diseases. Targeting these cytokines with biologics and small molecules has led to a major improvement of the bone health of patients with inflammatory arthritis. …”
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4-Methoxycarbonyl Curcumin: A Unique Inhibitor of Both Inflammatory Mediators and Periodontal Inflammation by Ying Gu, Hsi-Ming Lee, Nicole Napolitano, McKenzie Clemens, Yazhou Zhang, Timo Sorsa, Yu Zhang, Francis Johnson, Lorne M. Golub

“…Chronic inflammatory diseases such as periodontitis have been associated with increased risk for various medical conditions including diabetes and cardiovascular disease. …”
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Large soluble CD18 complexes with exclusive ICAM-1-binding properties are shed during immune cell migration in inflammation by Alexey Ferapontov, Anders Mellemkjær, Helen M. McGettrick, Thomas Vorup-Jensen, Tue W. Kragstrup, Kristian Juul-Madsen

“…Surprisingly, this regulation is tied to sCD18 complex size, opening new opportunities for therapeutic intervention in serious inflammatory diseases such as arthritis.…”
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The Role of Hyaluronan in Innate Defense Responses of the Intestine by Carol A. de la Motte, Sean P. Kessler

“…Here we discuss what is known about hyaluronan distribution during homeostasis and inflammatory diseases of the gut and discuss ways in which this glycosaminoglycan can participate in regulating innate host defense mechanisms. …”
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New Insights into Artesunate as a Pleiotropic Regulator of Innate and Adaptive Immune Cells by Lixian Lin, Zengqi Tang, Zhenrui Shi, Qing Guo, Hui Xiong

“…Although it shows promising application in many diseases, such as inflammatory diseases, hypersensitivity, autoimmune diseases, and cancers, little is known about underlying molecular. …”
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The Influence of Nutrients on Inflammatory Bowel Diseases by Sara Jarmakiewicz-Czaja, Dominika Piątek, Rafał Filip

“…Inflammatory bowel diseases is a group of inflammatory diseases. The pathogenesis of diseases is multifactorial, which may include a Western-type diet. …”
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Research progress in the role of β-arrestin 1 in the regulation of inflammatory response by YI Wenjing, FAN Yixuan, QIU Jiatai, FU Xiaoyan, LIU Meifang

“…Based on this, this article reviews the relevant research on ARRB1 and the inflammatory response in recent years, focusing on the regulatory role of ARRB1 in signaling pathway transduction and immune cell development and differentiation function, as well as its mechanism of action in regulating the progression of inflammatory diseases, in order to provide new insights for the clinical precision treatment of inflammatory diseases and the screening of drug effect targets.…”
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In vitro evaluation of the immunomodulatory and antibacterial activities of calcitriol (1,25-dihydroxy-vitamin D3) as a potential application for aerobic vaginitis treatment - prel... by Anna Tomusiak-Plebanek, Grażyna Więcek, Edyta Golińska, Magdalena Strus

“…Such properties could be very useful in the treatment of inflammatory diseases. However, conclusions regarding the potential use of calcitriol in the treatment of AV require further confirmation in in vivo studies as well as in well-designed clinical trials.…”
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Ribosomal proteins mediate non-canonical regulation of gut inflammatory signature by crop contaminant deoxynivalenol by Juil Kim, BoGyoung Song, Ki-Hyung Kim, Yuseok Moon

“…DON exposure disrupts ribosomal function, inducing stress responses linked to various inflammatory diseases, including inflammatory bowel disease (IBD). …”
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Suppression of matrix metalloproteinase-9 production from neutrophils by a macrolide antibiotic, roxithromycin, in vitro by Ken-Ichi Kanai, Kazuhito Asano, Tadashi Hisamitsu, Harumi Suzaki

“…BACKGROUND: Macrolide antibiotics such as erythromycin and roxithromycin (RXM) have an anti-inflammatory effect that may account for their clinical benefit in the treatment of chronic airway inflammatory diseases. However, the precise mechanism of this anti-inflammatory effect is not well understood.…”
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Systems immunology integrates the complex endotypes of recessive dystrophic epidermolysis bullosa by Nell Hirt, Enzo Manchon, Qian Chen, Clara Delaroque, Aurelien Corneau, Patrice Hemon, Safaa Saker-Delye, Pauline Bataille, Jean-David Bouaziz, Emmanuelle Bourrat, Alain Hovnanian, Helene Le Buanec, Fawzi Aoudjit, Hicham El Costa, Nabila Jabrane-Ferrat, Reem Al-Daccak

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Injectable double network hydrogel with adjustable stiffness for modulation of macrophage polarization by Jinxin Wu, Bing Han, Shili Ai, Aijing Wang, Yilin Song, Moran Jin, Xiaozhong Qu, Xiaoyan Wang

“…Additionally, the critical role of integrins in mediating mechanical transduction may provide new therapeutic targets for treating certain stiffness-related inflammatory diseases.…”
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The added value of coupling anti-dsDNA and anti-chromatin antibodies in follow-up monitoring of systemic lupus erythematosus patients by Caroline Carlé, Françoise Fortenfant, Chloé Bost, Julie Belliere, Stanislas Faguer, Dominique Chauveau, Antoine Huart, David Ribes, Laurent Alric, Gregory Pugnet, Laurent Sailler, Yves Renaudineau

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The Role of Poly(ADP-ribose) Polymerase-1 in Rheumatoid Arthritis by Samuel García, Carmen Conde

“…In addition to the role of PARP-1 in DNA repair, multiple studies have also demonstrated its involvement in several inflammatory diseases, such as septic shock, asthma, atherosclerosis, and stroke, as well as in cancer. …”
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Influence of a macrolide antibiotic, roxithromycin, on mast cell growth and activation in vitro by Toshikazu Shimane, Kazuhito Asano, Mayumi Suzuki, Tadashi Hisamitsu, Harumi Suzaki

“…Background: Long-term administration of macrolide antibiotics is recognized to be able to favorably modify the clinical condition of inflammatory diseases, such as diffuse panbronchiolitis and cystic fibrosis. …”
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Advances in engineered T cell immunotherapy for autoimmune and other non-oncological diseases by Qiaolin Huang, Xiaojian Zhu, Yicheng Zhang

“…In this review, we highlight recent advances in the engineering of T cells in non-oncology areas, including autoimmune and inflammatory diseases, infections, fibrosis, hemophilia, and aging. …”
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