Supramolecular prodrug inspiried by the Rhizoma Coptidis-Fructus Mume herbal pair alleviated inflammatory diseases by inhibiting pyroptosis by Wenhui Qian, Bei Zhang, Ming Gao, Yuting Wang, Jiachen Shen, Dongbing Liang, Chao Wang, Wei Wei, Xing Pan, Qiuying Yan, Dongdong Sun, Dong Zhu, Haibo Cheng

“…Huanglian-Wumei decoction (HLWMD) is a classic prescription used for treating inflammatory diseases, but the necessity of their combination and the exact underlying anti-inflammatory mechanism have not yet been elucidated. …”
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Integrating machine learning and structure-based approaches for repurposing potent tyrosine protein kinase Src inhibitors to treat inflammatory disorders by Muhammad Waleed Iqbal, Muhammad Shahab, Zakir ullah, Guojun Zheng, Irfan Anjum, Gamal A. Shazly, Atrsaw Asrat Mengistie, Xinxiao Sun, Qipeng Yuan

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Risk factors for Clostridioides difficile infection among patients diagnosed with inflammatory intestinal and rheumatological diseases in the biologic era by Helena Martínez-Lozano, Paula Saralegui-Gonzalez, Elena Reigadas, Pablo Ramón Fueyo-Peláez, Aurea García-García, José Miranda-Bautista, Luis Alcalá, Juan Carlos Nieto, María Elena Lobato-Matilla, Ignacio Marín-Jiménez, Patricia Muñoz, Luis Menchén

Subjects: “…Immune-mediated inflammatory diseases…”
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Mendelian randomization analysis does not support a causal influence between lipoprotein(A) and immune-mediated inflammatory diseases by Yun Ti, Dan Xu, Xiaoning Qin, Yang Hu, Yuru Xu, Qingzhao Zhao, Peili Bu, Jingyuan Li

Subjects: “…Immune-mediated inflammatory diseases…”
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Utility of pattern-based approach to skin biopsies in pediatric non-infectious inflammatory diseases: a review of 140 cases by Neha Singh, Suravi Mohanty, Rajalakshmi Tirumalae

“…Objective To evaluate the histopathologic spectrum of skin biopsies in pediatric noninfectious inflammatory diseases pediatric inflammatory diseases and its correlation with clinical findings. …”
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Efferocytosis and inflammation: a bibliometric and systematic analysis by Xin Cao, Xin Cao, Fen Li, Fen Li, Xi Xie, Xi Xie, Guanghui Ling, Guanghui Ling, Xiaoyu Tang, Xiaoyu Tang, Wenfang He, Jing Tian, Jing Tian, Yan Ge, Yan Ge

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Remarkable Role of Indoleamine 2,3-Dioxygenase and Tryptophan Metabolites in Infectious Diseases: Potential Role in Macrophage-Mediated Inflammatory Diseases by Yuki Murakami, Masato Hoshi, Yukio Imamura, Yuko Arioka, Yasuko Yamamoto, Kuniaki Saito

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An adenoviral vector encoding an inflammation-inducible antagonist, HMGB1 Box A, as a novel therapeutic approach to inflammatory diseases by Kari Ann Shirey, John Joseph, Lynda Coughlan, Haye Nijhuis, Alan W. Varley, Jorge C. G. Blanco, Stefanie N. Vogel

“…We anticipate that this strategy will apply to the treatment of multiple diseases in which HMGB1-mediated signaling is a central driver of inflammation.IMPORTANCEMany inflammatory diseases are mediated by the action of a host-derived protein, HMGB1, on Toll-like receptor 4 (TLR4) to elicit an inflammatory response. …”
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The Causal Relationship between Immune-Mediated Inflammatory Diseases and Aortic Aneurysm: A Bidirectional Two-Sample Mendelian Randomization Study by Sijia Sun, Jie Li, Mengxian Sun, Jie He, Songtao Tan, Ge Wang, Yuan Zheng, Xiaoping Fan

“…Observational studies have frequently linked aortic aneurysm (AA) to immune-mediated inflammatory diseases (IMIDs) as a cardiovascular complication. …”
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Neutrophil Lymphocyte Ratio, Platelet Lymphocyte Ratio and Mean Platelet Volume; which one is More Predictive in the Diagnosis of Pelvic Inflammatory Disease? by Kerem Doğa Seçkin, Mehmet Fatih Karslı, Burak Yücel, Burak Özköse, Doğukan Yıldırım, Berna Aslan Çetin, Halil Aslan

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Genetic Selection Pressure on TLR9 Gene Increases Individual Susceptibility to Systemic Inflammatory Disease: A Case Study of Kano State Population by Yusuf Jibril Habib, Mohammed Sani Jaafaru

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A Rare Case of Small Bowel Obstruction in a Patient with Endosalpingiosis, Fitz-Hugh-Curtis Syndrome, and Chlamydia trachomatis Pelvic Inflammatory Disease by Zhi Kiat Sia, Jodie Trautman, Takako Eva Yabe, James Wykes

“…The underlying cause of her small bowel obstruction could be due to pelvic inflammatory disease, Fitz-Hugh-Curtis syndrome, or endosalpingiosis. …”
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Recent advances in adipose-derived mesenchymal stem cell-derived exosomes for regulating macrophage polarization by Zhewei Dong, Yingli Fu, Zhongming Cai, Hao Dai, Yucang He

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A nested case-control study evaluating the relationship between adverse childhood experiences and immune-mediated inflammatory disease in the Canadian Longitudinal Study on Aging by Charles N Bernstein, Ruth Ann Marrie, Julia O'Mahony

“…Objective Adverse childhood experiences (ACE) have inconsistently been implicated as risk factors for immune-mediated inflammatory diseases (IMID). We evaluated whether the association of ACE with disease differs between IMID and other chronic diseases.Design Nested retrospective case-control study.Setting We used data from the Canadian Longitudinal Study on Aging (CLSA), which recruited participants aged 45–85 years between 2010 and 2015.Participants We included 12 627 CLSA participants: 2 102 who reported diagnoses of IMID (258 multiple sclerosis (MS), 1 692 rheumatoid arthritis (RA) and 160 inflammatory bowel disease (IBD)), 5 519 with diabetes, 170 with epilepsy, 3 889 with asthma and 1 125 with no chronic diseases. …”
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PATIENTS' CHRONOTYPE INFLUENCE IN TREATMENT EFFICIENCY OF PLACENTA CRYERXTRACT CHANGES IN MAXILLOFACIAL PHLEGMONS by K. Lokes, M. Pérez Sayáns, V. Lychman, D. Steblovskyi, I. Boiko, D. Avetikov

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The relationship between involutional ectropion and inflammatory disorders of the eyelids and ocular surface: insights from a large-scale national study by Ahmad Mansour, Tomer Kerman, Nir Amitai, Eran Zunz, Soltan Khalaila, Itai Hazan, Erez Tsumi

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Real-World Evidence of Clinical Outcomes of the Use of the Adalimumab Biosimilar SB5 in Rheumatic and Gastrointestinal Immune-Mediated Inflammatory Diseases: 12-Month Data from the PERFUSE Study by Bruno Fautrel, Yoram Bouhnik, Carine Salliot, Franck Carbonnel, Mathurin Fumery, Christophe Bernardeau, Yves Maugars, Mathurin Flamant, Fabienne Coury, Ben Braithwaite, Salima Hateb, Janet Addison, the PERFUSE investigators

“…Methods PERFUSE is a 12-month, observational, multi-centre cohort study of patients with rheumatic or gastrointestinal immune-mediated inflammatory diseases (IMIDs) who initiated routine SB5 treatment between October 2018 and October 2020, either as their first ADL (naïve) or transitioning from another ADL (switched). …”
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Obesity and Chronic Inflammation: Implications for Rheumatoid Arthritis, Spondyloarthritis, and Ulcerative Colitis by Ada Corrado, Ilaria Guadagni, Giovanna Picarelli, Angela Variola

Subjects: “…immune‐mediated inflammatory diseases (IMIDs)…”
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Can the Risk Factors Predicting Surgical Treatment be Determined in Patients with Tubo-Ovarian Abscess? by Tayfun Vural, Burak Bayraktar, Suna Yildirim Karaca, Emir Gurbuz, Mehmet Ozeren, Cuneyt Eftal Taner

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IL-1 and its role in rat carrageenan pleurisy by R. Goodman, L. R. Mantegna, C. L. McAIlister, E. Bruin, R. L. Dowling, H. George, W. Feeser, B. Freimark, M. Lischwe, S. Pick, R. R. Harris, J. S. Kerr

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