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301
Histone demethylases in autophagy and inflammation
Published 2025-01-01“…By analyzing each KDM in epigenetic modification, this review provides a reliable theoretical basis for clinical decision marking regarding autophagy abnormalities and inflammatory diseases.…”
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302
Anti-Inflammatory Effect of Columbianetin on Lipopolysaccharide-Stimulated Human Peripheral Blood Mononuclear Cells
Published 2018-01-01“…Columbianetin (CBT) is derived from the root of the Chinese herb Radix Angelicae Pubescentis for treating inflammatory diseases. Although the anti-inflammatory effect of CBT has been reported, its anti-inflammatory mechanism was poorly studied. …”
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303
miR663 Prevents Epo Inhibition Caused by TNF-Alpha in Normoxia and Hypoxia
Published 2021-01-01“…Objective. In chronic inflammatory diseases, proinflammatory cytokines such as TNF-α are present in high amounts in the circulation and are associated with anemia in most cases. …”
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304
Purine-Metabolizing Ectoenzymes Control IL-8 Production in Human Colon HT-29 Cells
Published 2014-01-01“…Interleukin-8 (IL-8) plays key roles in both chronic inflammatory diseases and tumor modulation. We previously observed that IL-8 secretion and function can be modulated by nucleotide (P2) receptors. …”
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305
Erbin Regulates Tissue Factors Through Ras/Raf Pathway in Coagulation Disorders in Sepsis
Published 2025-02-01“…It has been reported that ERBB2 Interacting Protein (Erbin) is involved in the development of various inflammatory diseases, and macrophages are involved in the regulation of coagulation disorders in sepsis. …”
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306
Theranostic nanoemulsions suppress macrophage-mediated acute inflammation in rats
Published 2025-02-01“…Abstract In inflammatory diseases or following an injury, dysregulated inflammation is a common driver of pain and tissue damage. …”
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307
Chloroquine and Rapamycin Augment Interleukin-37 Expression via the LC3, ERK, and AP-1 Axis in the Presence of Lipopolysaccharides
Published 2020-01-01“…IL-37 is a cytokine that plays critical protective roles in many metabolic inflammatory diseases, and its therapeutic potential has been confirmed by exogenous IL-37 administration. …”
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308
Reduction of IL-17A Might Suppress the Th1 Response and Promote the Th2 Response by Boosting the Function of Treg Cells during Silica-Induced Inflammatory Response In Vitro
Published 2014-01-01“…IL-17A, the typical Th17 cytokine, is reported in some inflammatory diseases. However, the role of IL-17A in silica-induced inflammatory response is still not clear. …”
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309
Alpha-1 Antitrypsin as a Regulatory Protease Inhibitor Modulating Inflammation and Shaping the Tumor Microenvironment in Cancer
Published 2025-01-01“…This review seeks to bridge the gap in the understanding of AAT between inflammatory diseases and cancer, and to foster deeper investigations into its translational potential in cancer immunotherapy in the future.…”
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310
Neolithic introgression of IL23R-related protection against chronic inflammatory bowel diseases in modern EuropeansResearch in context
Published 2025-03-01“…The adaptively evolved function of the variant likely contributes to the high efficacy and low side-effects of modern IL-23 neutralisation therapies for chronic inflammatory diseases. Funding: German Research Foundation (EXC 2167 390884018 and EXC 2150 390870439).…”
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311
Omentin-1, a Protective Adipokine for Irritable Bowel Syndrome
Published 2025-02-01“…Adipokines have been reported to be critical immunoregulators in many clinical conditions, including gastrointestinal (GI) inflammatory diseases. Our study aimed to investigate associations of omentin-1 (a newly discovered adipokine) with IBS.Methods: In the current study, serum levels of omentin-1 were measured in 209 patients with IBS (including three subtypes) and 188 healthy controls by enzyme-linked immunosorbent assay (ELISA). …”
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312
Th9 Cells in Peripheral Blood Increased in Patients with Immune-Related Pancytopenia
Published 2020-01-01“…Th9 cells are associated with a variety of inflammatory diseases, but the role of Th9 cells in IRP remains unclear. …”
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313
The role of natural exosomes from SHED-MSC in immunoregulation of M0/M1 polarized macrophage cells
Published 2025-02-01“…IntroductionExosomes (EXOs) as a targeted cell-free therapy could offer a new therapeutic strategy for immune-mediated inflammatory diseases, due to their stability and ease of storage and handling. …”
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314
MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology
Published 2025-02-01“…Regulation makes it a potential target for treating diseases, especially cardiovascular diseases, neurodegenerative diseases, inflammatory diseases, metabolic diseases, and tumors.…”
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315
Exosomes Play an Important Role in the Progression of Plasma Cell Mastitis via the PI3K-Akt-mTOR Signaling Pathway
Published 2019-01-01“…Plasma cell mastitis (PCM) is one of the most frequently encountered inflammatory diseases of the nonlactating breast. However, its pathogenesis has remained unknown. …”
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316
Wnt signaling as a translational target in rheumatoid and psoriatic arthritis
Published 2025-02-01“…Abstract Background Rheumatoid arthritis (RA) and Psoriatic arthritis (PsA) are chronic inflammatory diseases mainly affecting joints. RA primarily targets the synovial joints and is characterized by cartilage and bone erosion, whereas PsA is associated with skin and nail psoriasis and is characterized by erosive bone damage with an exuberant bone formation and soft tissue involvement. …”
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317
Decreased Soluble Receptor of Advanced Glycation End Product Levels Correlated with Inflammation in Silicosis
Published 2020-01-01“…Increasing evidences indicate that soluble receptor for advanced glycation end products (sRAGE) is involved in inflammatory diseases. However, no data on the possible relationship between sRAGE and inflammation of silicosis are available. …”
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318
Unveiling the Potency of Gardenia Extract Against <i>H. pylori</i>: Insights from In Vitro and In Vivo Studies
Published 2025-01-01“…Background and aim: <i>Gardenia jasminoides</i> (<i>G. jasminoides</i>) could treat various inflammatory diseases. This study aimed to investigate the effects of <i>G. jasminoides</i> fruit extract on gastric inflammation and protective mechanisms in <i>Helicobacter pylori</i> (<i>H. pylori</i>)-induced gastritis. …”
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319
Identification and Functional Analysis of PANoptosis‐Associated Genes in the Progression From Sepsis to ARDS
Published 2025-01-01“…PANoptosis, a newly discovered form of programmed cell death involving multiple cell death pathways, plays a critical role in inflammatory diseases. This study aims to elucidate the PANoptosis‐related genes (PRGs) and their involvement in the progression of sepsis to ARDS. …”
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320
Vaccine Prophylaxis of Pneumococcal Infections in Children under Conditions of Severe Flood in the Amur River Basin
Published 2019-01-01“…To study the circulation of serovariants of pneumococcus in inflammatory diseases of the respiratory tract and nasopharyngeal carrier, bacteriological and molecular genetic methods (RT-PCR in the mode of multiprime detection) were used. …”
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