Actin-Binding Proteins as Potential Biomarkers for Chronic Inflammation-Induced Cancer Diagnosis and Therapy by Yu-Gui Zhang, Jiang-Tao Niu, Hong-Wei Wu, Xin-Lei Si, Shu-Juan Zhang, Dong-Hui Li, Tian-Tian Bian, Yue-Feng Li, Xing-Ke Yan

“…This article discusses the relationship between chronic inflammation and the above-mentioned cancers, emphatically introduces relevant research on the abnormal expression of ABPs in chronic inflammatory diseases, and reviews research on the expression of different ABPs in the above-mentioned cancers. …”
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Atrioventricular Conduction Delay in the Second Trimester Measured by Fetal Magnetocardiography by Annette Wacker-Gussmann, Henrike Paulsen, Krunoslav Stingl, Johanna Braendle, Rangmar Goelz, Joerg Henes

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Fatty Acid Contents and Stability of Oyster Nut Oil (Telfairia pedata) Compared to Flaxseed and Sunflower Oil by Emmanuel Mwakasege, Anna Treydte, Otmar Hoeglinger, Neema Kassim, Edna Makule

“…Linoleic acid (LA) (omega-6) and alpha-linolenic acid (ALA) (omega-3) are essential polyunsaturated fatty acids required for the maintenance of good health; however, LA derivatives such as arachidonic acid (AA) are associated with the onset of inflammatory diseases, and both are prone to oxidation and deterioration. …”
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hUC-MSCs Attenuate Acute Graft-Versus-Host Disease through Chi3l1 Repression of Th17 Differentiation by Weijiang Liu, Fulin Yuan, Haitao Bai, Yuanlin Liu, Xue Li, Yang Wang, Yi Zhang

“…Mesenchymal stem cells (MSCs) have already demonstrated definitive evidence of their clinical benefits in acute graft-versus-host disease (aGvHD) and other inflammatory diseases. However, the comprehensive mechanism of MSCs’ immunomodulation properties has not been elucidated. …”
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Mouse Mesenchymal Progenitor Cells Expressing Adipogenic and Osteogenic Transcription Factors Suppress the Macrophage Inflammatory Response by Natalie Fernandez, Heather Renna, Lauren McHugh, Katie Mazolkova, William Crugnola, Jodi F. Evans

“…These data will be useful for the isolation, purification, and modification of mesenchymal progenitors to be used in the treatment of inflammatory diseases.…”
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Natural Killer T (NKT) Cells and Periodontitis: Potential Regulatory Role of NKT10 Cells by Samanta Melgar-Rodríguez, Emilio A. Cafferata, Nicolás I. Díaz, Miguel A. Peña, Luis González-Osuna, Carolina Rojas, Alfredo Sierra-Cristancho, Angélica M. Cárdenas, Jaime Díaz-Zúñiga, Rolando Vernal

“…Although the tissue-specific functions of NKT cells have not been fully elucidated, their activity has been associated with the pathogenesis of different inflammatory diseases with immunopathogenic similarities to periodontitis, including osteolytic pathologies such as rheumatoid arthritis and osteoporosis. …”
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Serum Calprotectin Level as an Inflammatory Marker in Newly Diagnosed Hypertensive Patients by Nergiz Bayrakci, Gülsüm Ozkan, Sonat Pinar Kara, Ahsen Yilmaz, Savas Guzel

“…Calprotectin is an inflammatory marker that rises in parallel with disease activity in conditions such as systemic inflammatory diseases, infection, and atherosclerosis. The purpose of this study was to evaluate inflammation through serum calprotectin levels in newly diagnosed primary hypertension patients. …”
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Selenoprotein S Attenuates Tumor Necrosis Factor-α-Induced Dysfunction in Endothelial Cells by Siyuan Cui, Lili Men, Yu Li, Yingshuo Zhong, Shanshan Yu, Fang Li, Jianling Du

“…These findings suggest that SelS protects endothelial cells against TNF-α-induced dysfunction by inhibiting the activation of p38 MAPK and NF-κB pathways and implicates it as a possible modulator of vascular inflammatory diseases.…”
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Caffeoylquinic Acid Derivatives Extract of Erigeron multiradiatus Alleviated Acute Myocardial Ischemia Reperfusion Injury in Rats through Inhibiting NF-KappaB and JNK Activations by Zhifeng Zhang, Yuan Liu, Xuecong Ren, Hua Zhou, Kaishun Wang, Hao Zhang, Pei Luo

“…Benth. has been used in Tibet folk medicine to treat various inflammatory diseases. The aim of this study was to investigate antimyocardial ischemia and reperfusion (I/R) injury effect of caffeoylquinic acids derivatives of E. multiradiatus (AE) in vivo and to explain underling mechanism. …”
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The relationship between histamine receptor type 4 gene polymorphism (rs11662595) and response to H1 antihistamine drugs in patients with chronic idiopathic urticaria by Ebrahim Mohammadi, Fakhredin Karimpour, Ramin Lotfi, Fatemeh Zamani, Abbas Aghaei, Rasoul Nasiri Kalmarzi

“…Materials and Methods 130 patients with confirmed chronic idiophatic urticaria (CIU) and no other infectious or inflammatory diseases were selected for this study. With the consent of the patients, 5 ml of peripheral blood was taken from each patient for DNA extraction (in a CBC tube) and IgE measurement (in a hemolysis tube without anticoagulant). …”
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The Long Noncoding RNA Gm9866/Nuclear Factor-κB Axis Promotes Macrophage Polarization by Xiaomin Liao, Xianxian Ruan, Xiubing Chen, Biaolin Zheng, Xianbin Wu, Zhejun Deng, Zhe Yang, Feng Wang, Shanyu Qin, Haixing Jiang

“…Thus, long noncoding RNA Gm9866 may serve as a potential diagnostic and therapeutic target for polarization-related diseases such as infectious diseases, inflammatory diseases, liver fibrosis, and tumors.…”
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Glycyrrhizin attenuates renal inflammation in a mouse Con A-hepatitis model via the IL-25/M2 axis by Lingyun Li, Yuanyue Zhang, Zhongyan Wang, Xiangyu Chen, Min Fang

“…Glycyrrhizin (GL) has immunoregulatory effects on various inflammatory diseases including hepatitis and nephritis. …”
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Cyanidin-3-O-Glucoside Modulates the In Vitro Inflammatory Crosstalk between Intestinal Epithelial and Endothelial Cells by Daniela Ferrari, Francesco Cimino, Deborah Fratantonio, Maria Sofia Molonia, Romina Bashllari, Rossana Busà, Antonella Saija, Antonio Speciale

“…Thus, anthocyanins could contribute to the management of chronic gut inflammatory diseases.…”
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Thrombin Induces COX-2 and PGE2 Expression via PAR1/PKCalpha/MAPK-Dependent NF-kappaB Activation in Human Tracheal Smooth Muscle Cells by Chien-Chung Yang, Li-Der Hsiao, Ya-Fang Shih, Chih-Kai Hsu, Chia-Yu Hu, Chuen-Mao Yang

“…COX-2 induction by thrombin has been shown to play a vital role in various inflammatory diseases. However, in human tracheal smooth muscle cells (HTSMCs), how thrombin enhanced the levels of COX-2/PGE2 is not completely characterized. …”
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Intra-uterine Growth Restriction Downregulates the Hepatic Toll Like Receptor-4 Expression and Function by Ozlem Equils, Sapna Singh, Semra Karaburun, Daning Lu, Manikkavasagar Thamotharan, Sherin U. Devaskar

“…We propose that IUGR dysregulates TLR4 expression and function in the offspring, which may help explain the increased risk of Gram-negative sepsis and inflammatory diseases in this population.…”
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IL-21 Receptor Expression in Human Tendinopathy by Abigail L. Campbell, Nicola C. Smith, James H. Reilly, Shauna C. Kerr, William J. Leach, Umberto G. Fazzi, Brian P. Rooney, George A. C. Murrell, Neal L. Millar

“…The IL-21/IL-21R axis is a proinflammatory cytokine complex that has been associated with chronic inflammatory diseases including rheumatoid arthritis and inflammatory bowel disease. …”
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Epigenome-wide association study of perceived discrimination in the Multi-Ethnic Study of Atherosclerosis (MESA) by Wei Zhao, Lisha Lin, Kristen M. Kelly, Lauren A. Opsasnick, Belinda L. Needham, Yongmei Liu, Srijan Sen, Jennifer A. Smith

“…Identified CpGs and/or nearby genes have been implicated in cellular development pathways, transcription factor binding, cancer and multiple autoimmune and/or inflammatory diseases. Of the identified CpGs (7 individual CpGs and 11 within DMRs), two CpGs and one CpG within a DMR were associated with expression of cis genes NDUFS5, AK1RIN1, NCF4 and ADSSL1. …”
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Pharmacological Inhibition of Caspase-1 Ameliorates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation in Mice by Jung-Yeon Kim, Jae-Hyung Park, Kiryeong Kim, Jungmin Jo, Jaechan Leem, Kwan-Kyu Park

“…Caspase-1 is a proinflammatory caspase responsible for the proteolytic conversion of the precursor forms of interleukin-1β to its active form and plays an important role in the pathogenesis of various inflammatory diseases. It was reported that genetic deficiency of caspase-1 prevented cisplatin-induced nephrotoxicity. …”
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Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential by Masayo Aoki, Hiroaki Aoki, Rajesh Ramanathan, Nitai C. Hait, Kazuaki Takabe

“…We also discuss the role of S1P-S1PR1 axis in inflammatory diseases and wound healing.…”
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Circulating CD3+HLA-DR+ Extracellular Vesicles as a Marker for Th1/Tc1-Type Immune Responses by Ryutaro Oba, Motomichi Isomura, Akira Igarashi, Kinya Nagata

“…To evaluate the clinical usefulness of these EVs, we measured the serum levels in patients with inflammatory diseases, including Epstein-Barr virus (EBV, n=13) infection, atopic dermatitis (AD, n=10), rheumatoid arthritis (RA, n=20), and osteoarthritis (OA, n=20) and compared the levels with those of healthy adults (n=20). …”
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