Faecalibacterium prausnitzii: A Next-Generation Probiotic in Gut Disease Improvement by Xiaoya He, Shuyang Zhao, Yan Li

“…It is reported that intervention with higher richness of F. prausnitzii through dietary modulation, fecal microbiota transplantation, or culture strategy can protect the mice or the subjects from inflammatory diseases. Therefore, F. prausnitzii may have potential ability to reduce microbial translocation and inflammation, preventing occurrences of gastrointestinal comorbidities especially in COVID-19 patients.…”
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The Perspective of Therapeutic Antibody Marketing in Iran: Trend and Estimation by 2025 by Monireh Golpour, Pouya Vatanpour, Mina Amini, Majid Saeedi, Nasim Hafezi, Alireza Rafiei

“…Monoclonal antibodies with high efficiency and specificity are one of the best strategies to diagnose and treat a variety of diseases such as cancer, autoimmunity, and inflammatory diseases. The market for monoclonal therapeutic antibodies (MTAs) has grown dramatically in the past decade. …”
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Blockade of PLD2 Ameliorates Intestinal Mucosal Inflammation of Inflammatory Bowel Disease by Guangxi Zhou, Lin Yu, Wenjing Yang, Wei Wu, Leilei Fang, Zhanju Liu

“…Phospholipase D2 (PLD2) is reported to be involved in the pathogenesis of several inflammatory diseases. However, the exact role of PLD2 in IBD is obscure. …”
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Negative Effects of SIGIRR on TRAF6 Ubiquitination in Acute Lung Injury In Vitro by Feng Tian, Qiang Lu, Jie Lei, Yunfeng Ni, Nianlin Xie, Daixing Zhong, Guang Yang, Shaokui Si, Tao Jiang

“…The current study reveals the molecular mechanisms of the negative regulatory roles of SIGIRR on the innate immune response related to the LPS/TLR-4 signaling pathway and provides evidence for strategies to clinically treat inflammatory diseases.…”
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Modern potential of preparation of intestine to endoscopy in pediatric practice by S. I. Erdes, N. M. Leonevskaya, M. M. Lokhmatov, M. A. Ratnikova, T. N. Budkina

“…Exclusion criteria were: incomplete/complete ileus, megacolon (congenital/acquired), acute inflammatory diseases and disorder of large intestine integrity, renal/ heart failure. …”
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Baicalin and Baicalein Inhibit Src Tyrosine Kinase and Production of IL-6 by Dubravko Jelić, Agnieszka D. Lower-Nedza, Adelheid H. Brantner, Biljana Blažeković, Baolin Bian, Jian Yang, Karmen Brajša, Sanda Vladimir-Knežević

“…Flavonoids play an important role in the treatment of various diseases, as they are able to inhibit reactive oxygen species, which cause damage to cells and tissues which may lead to increased risk of inflammatory diseases. Baicalin and baicalein, two flavonoids found in the roots of Scutellaria baicalensis, in the leaves of Thymus vulgaris and Oroxylum indicum, were tested for their anti-inflammatory activity as well as for their cytotoxicity. …”
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Trachoma and Ocular Chlamydial Infection in the Era of Genomics by Tamsyn Derrick, Chrissy h. Roberts, Anna R. Last, Sarah E. Burr, Martin J. Holland

“…Each of these factors or processes contributes to pathogenic outcomes in other inflammatory diseases and we outline their potential role in trachoma.…”
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Effect of cyclosporin A on inflammatory cytokine production by U937 monocyte-like cells by Juan E. Losa Garcia, María Rosa Martín de Cabo, Fernando Mateos Rodríguez, Jesús Pérez Losada, Antonio Jiménez López, José Luis Pérez Arellano

“…Cyclosporin A (CsA) is an immunosuppresor drug that has been used in the treatment of several types of inflammatory diseases. In some of them the inhibition of T-lymphocyte activation does not suitably account for the observed beneficial effect, suggesting that CsA could act on other types of cells. …”
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Alternative treatment methods for bovine mastitis: prospects and limitations (review) by V. D. Zubareva, O. V. Sokolova, M. V. Bytov, A. S. Krivonogova, S. V. Volskaya

“…Antibacterial drugs remain first line agents for therapy of the mammary gland inflammatory diseases in animals. Taking into account the risks associated with antibiotic therapy, such as decreased drug effectiveness due to occurrence of bacterial resistant strains, food safety issues, environmental impact and restrictions on the use of antibacterial drugs in veterinary medicine, an increasing number of scientific studies are addressing new therapeutic agents that can serve as an alternative to conventional therapy. …”
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Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation by Giuseppe Vassalli, Giuseppina Milano, Tiziano Moccetti

“…Small-molecule p38 MAPK inhibitors have been tested clinically in patients with chronic inflammatory diseases, but not in transplanted patients, so far. …”
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The Effect of Periodontitis on Expression of Interleukin-21: A Systematic Review by Archana Mootha, Sankari Malaiappan, N. D. Jayakumar, Sheeja S. Varghese, Julie Toby Thomas

“…Inflammation and tissue breakdown are led by an array of inflammatory destructive mediators associated with initiation and progression of inflammatory diseases like periodontitis. Current evidence shows that these inflammatory mediators have a definitive role in the pathogenesis of various systemic diseases with an inflammatory component. …”
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The spectrum of giant cell arteritis and polymyalgia rheumatica: a longitudinal prospective study to assess for subclinical giant cell arteritis in new onset polymyalgia rheumatica by Yasser El Miedany, Maha El Gaafary, Mathias Toth, Sami Bahlas, Waleed Hassan, Safaa Mahran, Mohammed Hassan Abu-Zaid, Ali El Miedany, Walaa Elwakil

“…The strong relationship between PMR and GCA raises the question of whether it is a “co-occurrence of different diseases” or a “common spectrum of inflammatory diseases.” The objectives of the current study were to assess the applicability of using ultrasound (US) and clinical data as a monitoring tool to identify PMR patients with subclinical GCA and determine possible predictors of GCA among PMR patients. …”
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Hyaluronan Synthase 3 Null Mice Exhibit Decreased Intestinal Inflammation and Tissue Damage in the DSS-Induced Colitis Model by Sean P. Kessler, Dana R. Obery, Carol de la Motte

“…Hyaluronan (HA) overproduction is a hallmark of multiple inflammatory diseases, including inflammatory bowel disease (IBD). …”
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Free radicals and their impact on health and antioxidant defenses: a review by Nisansala Chandimali, Seon Gyeong Bak, Eun Hyun Park, Hyung-Jin Lim, Yeong-Seon Won, Eun-Kyung Kim, Sang-Ik Park, Seung Jae Lee

“…Chronic conditions such as cancer, cardiovascular diseases, neurodegenerative disorders, and inflammatory diseases have been strongly associated with the harmful effects of free radicals. …”
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TNF-α Autocrine Feedback Loops in Human Monocytes: The Pro- and Anti-Inflammatory Roles of the TNF-α Receptors Support the Concept of Selective TNFR1 Blockade In Vivo by Jennie M. Gane, Robert A. Stockley, Elizabeth Sapey

“…Selective TNFR1 blockade in inflammatory diseases is emerging as a clinical strategy. …”
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Interplay between Extracellular Matrix and Neutrophils in Diseases by Yanyan Zhu, Yumeng Huang, Qian Ji, Shengqiao Fu, Jia Gu, Ningzheng Tai, Xu Wang

“…A better comprehension of immune cell-matrix reciprocal dependence has exciting implications for the development of new therapeutic options for neutrophil-associated infectious and inflammatory diseases.…”
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Evaluation of Faecal Microbiota Following Probiotics in Infants of Mothers with Gestational Diabetes Mellitus Trial: Protocol for Double-Blind Placebo-Controlled Randomized Trial by Gayatri Athalye-Jape, Chandra Prakash Rath, Harshad Panchal, Archita Mishra, Dorothy Graham, Sanjay Patole

“…The current evidence indicates that GDM, especially in conjunction with maternal overweight, can alter the composition of infants’ gut microbiota, potentially increasing the risk of inflammatory diseases, metabolic disorders, and neurodevelopmental issues later in life. …”
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The relationship of growth differentiation factor 15 with some biochemical parameters in cardiovascular disease patients in Babylon City by Hiba Resheed Behayaa, Zinah Abbass Ali, Seenaa Badr Mohammed, Suhayr A. Alqaysi

“…Growth differentiation factor 15 (GDF15) is about cachexia, CVD, and a lot of inflammatory diseases. GDF15 is very low in most tissues, except the placenta (in healthy conditions), which expresses GDF15 in high levels. …”
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Interleukin-22 Might Act as a Double-Edged Sword in Type 2 Diabetes and Coronary Artery Disease by Fangchen Gong, Jin Wu, Ping Zhou, Mengyao Zhang, Jingning Liu, Ying Liu, Xiang Lu, Zhengxia Liu

“…Our results suggest that IL-22 functions as a double-edged sword in T2DM and CAD and that IL-22 may be used in the treatment of chronic inflammatory diseases such as T2DM and CAD.…”
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Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2 in Diabetic OVE Mice by Shirong Zheng, Susan Coventry, Lu Cai, David W. Powell, Venkatakrishna R. Jala, Bodduluri Haribabu, Paul N. Epstein

“…ACKR2 is known to regulate diverse inflammatory diseases but its role in DN has not been tested. …”
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