Type 2 Diabetes, PUFAs, and Vitamin D: Their Relation to Inflammation by Ana L. Guadarrama-López, Roxana Valdés-Ramos, Beatríz E. Martínez-Carrillo

“…On the other hand, there is evidence about the beneficial effect of polyunsaturated fatty acids (PUFA) n-3 and n-6 in patients with chronic inflammatory diseases including diabetes. Furthermore, high vitamin D plasmatic concentrations have been associated with the best performance of pancreatic β cells and the improving of this disease. …”
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Vascular cytoprotection, autoimmune disease, and premature atherosclerosis by Justin C Mason

“…Endothelial injury and apoptosis leads to endothelial dysfunction, which is closely associated with increased generation of reactive oxygen species, reduced endothelial nitric oxide (NO) synthase, increased consumption, and impaired synthesis of NO. Systemic inflammatory diseases including rheumatoid arthritis and systemic lupus erythematosus are associated with endothelial dysfunction, increased aortic stiffness, and accelerated atherogenesis. …”
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Pharmacological Inactivation of Src Family Kinases Inhibits LPS-Induced TNF-α Production in PBMC of Patients with Behçet’s Disease by Sevgi Irtegun, Gulsum Pektanc, Zeynep M. Akkurt, Mehtap Bozkurt, Fatih M. Turkcu, Sevgi Kalkanli-Tas

“…Behçet’s disease (BD) is a multisystemic chronic inflammatory disease characterized by relapsing oral and genital ulcers, uveitis, and skin lesions. …”
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Celiac Disease and Dermatologic Manifestations: Many Skin Clue to Unfold Gluten-Sensitive Enteropathy by Marzia Caproni, Veronica Bonciolini, Antonietta D'Errico, Emiliano Antiga, Paolo Fabbri

“…Among these there are both autoimmune, allergic, and inflammatory diseases, but also a more heterogeneous group called miscellaneous. …”
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LPA Promotes T Cell Recruitment through Synthesis of CXCL13 by Weili Hui, Chenqi Zhao, Sylvain G. Bourgoin

“…Lysophosphatidic acid (LPA) is a bioactive phospholipid playing an important role in various inflammatory diseases by inducing expression and secretion of many inflammatory cytokines/chemokines. …”
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Ferroptosis and pyroptosis are connected through autophagy: a new perspective of overcoming drug resistance by Peng Zhao, Shuangshuang Yin, Yuling Qiu, Changgang Sun, Haiyang Yu

“…Therefore, it also plays an important role in the progression of some chronic inflammatory diseases. This review discusses the relationship between autophagy, ferroptosis and pyroptosis, and attempts to uncover the reasons behind the evasion of tumor cell death and the nature of drug resistance.…”
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Influence of Helicobacter pylori Infection on Metabolic Syndrome in Old Chinese People by Wen Yang, Cunfu Xuan

“…H. pylori infection is one of the most common chronic infectious inflammatory diseases worldwide and is also a risk factor for atherosclerosis. …”
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Panoptosis – new frontier in research in head neck cancer by Shrikant B. Mali

“…It has been linked to the development of multiple systemic diseases in the human body, including infectious diseases, cancer, neurodegenerative diseases, and inflammatory diseases. The innate immune system provides the first line of defense against cellular perturbations, and inflammatory programmed cell death is elicited in response to microbial infections or alterations in cellular homeostasis. …”
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Anti-inflammatory actions of acupuncture by Freek J. Zijlstra, Ineke van den Berg-de Lange, Frank J. P. M. Huygen, Jan Klein

“…The attributive effect of acupuncture has been investigated in inflammatory diseases, including asthma, rhinitis, inflammatory bowel disease, rheumatoid arthritis, epicondylitis, complex regional pain syndrome type 1 and vasculitis. …”
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Medicinal Potential of Pine Trees: A Brief Review Focusing on Three Species by Qinsong Li, Qiyu Li, Anping Wang, Wenxuan Quan

“…The wide range of pharmacological activities of these bioactive components is helpful for the treatment of cardiovascular diseases, inflammatory diseases, tumors, and other diseases. These findings can help promote research on the medicinal potential of Pinus and its organs to realize the efficient utilization of byproducts of pine resources.…”
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TNF Tolerance in Monocytes and Macrophages: Characteristics and Molecular Mechanisms by René Huber, Rolf Bikker, Bastian Welz, Martin Christmann, Korbinian Brand

“…Otherwise, tolerance may also be a trigger of immune paralysis thus contributing to severe inflammatory diseases such as sepsis. An improved understanding of TNF tolerance will presumably facilitate the implementation of diagnostic or therapeutic approaches to more precisely assess and treat inflammation-related diseases.…”
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A synthetic chronogenetic gene circuit for programmed circadian drug delivery by Lara Pferdehirt, Anna R. Damato, Kristin L. Lenz, Maria F. Gonzalez-Aponte, Daniel Palmer, Qing-Jun Meng, Erik D. Herzog, Farshid Guilak

“…Rheumatoid arthritis and other inflammatory diseases are characterized by diurnal changes in cytokines, leading to inflammatory flares, with peak disease activity in the early morning. …”
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Mitochondria-Targeted Biomaterials-Regulating Macrophage Polarization Opens New Perspectives for Disease Treatment by Tian Z, Wang X, Chen S, Guo Z, Di J, Xiang C

“…The balance between pro-inflammatory and anti-inflammatory macrophages plays a pivotal role in the progression of inflammatory diseases. Mitochondria, often referred to as the “power plants” of the cell, are essential organelles responsible for critical functions such as energy metabolism, material synthesis, and signal transduction. …”
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New Onset of Dermatomyositis/Polymyositis during Anti-TNF-α Therapies: A Systematic Literature Review by Alexandra Maria Giovanna Brunasso, Werner Aberer, Cesare Massone

“…The emergence of DM/PM and antisynthetase syndrome seem to be associated with the use of anti-TNF-α agents, especially in patients with chronic inflammatory diseases (mainly RA) with positive autoantibodies before therapy initiation. …”
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Effects of shading and water availability on Kalanchoe pinnata (Lam.) Pers. (Crassulaceae) metabolite profile via a LC-MS-based untargeted metabolomics approach by Guilherme Perez Pinheiro, Álex Aparecido Rosini Silva, Andréia de Melo Porcari, Alexandra Christine Helena Frankland Sawaya

“…Pers. is a medicinal plant frequently used in folk medicine for treatment of inflammatory diseases and others. Several classes of bioactive compounds have been reported in extracts of this species, including flavonoids, which may increase/decrease in intensity according to environmental factors; therefore, we investigated the effects of shading and water availability treatments on the metabolic profile of extracts of K. pinnata analyzed via UHPLC-QTOF-MS. …”
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Pro-Inflammatory Cytokine-Mediated Anemia: Regarding Molecular Mechanisms of Erythropoiesis by F. Morceau, M. Dicato, M. Diederich

“…Anemia of cancer and chronic inflammatory diseases is a frequent complication affecting quality of life. …”
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A potential therapeutic approach for ulcerative colitis: targeted regulation of mitochondrial dynamics and mitophagy through phytochemicals by Jianping Zhou, Yuting Xi, Ting Wu, Xiaoyu Zeng, Jun Yuan, Lei Peng, Hao Fu, Ce Zhou

“…They can generate reactive oxygen species (ROS) which is a major contributor to inflammatory diseases such as ulcerative colitis (UC). In this review, we discuss the key effects of mitochondrial dynamics and mitophagy on the pathogenesis of UC, with a particular focus on the cellular energy metabolism, oxidative stress, apoptosis, and immunoinflammatory activities. …”
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Physiologically-based pharmacokinetic modeling of enantioselective hydroxychloroquine kinetics and impact of genetic polymorphisms by Gabriella de Souza Gomes Ribeiro, Leandro Francisco Pippa, Fernanda de Lima Moreira, Natália Valadares de Moraes

“…Abstract Hydroxychloroquine (HCQ) is a chiral drug used to treat malaria and inflammatory diseases, available as a racemic mixture of R-and S-HCQ. …”
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Analysis of restoration in atrophic scar by intradermal autologous dermal tissue: a pilot study by Sudhir Singh, Adarsh L. Singh, Deepika Singh

“…Objective To assess the efficacy of autologous dermal tissue transplantation in correcting atrophic scars due to trauma, acne vulgaris, varicella infection, and other inflammatory diseases and to evaluate any side effects associated with the procedure. …”
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Adipokines as Drug Targets in Diabetes and Underlying Disturbances by Vinícius Andrade-Oliveira, Niels O.S. Câmara, Pedro M. Moraes-Vieira

“…Several adipokines contribute to the self-styled “low-grade inflammatory state” of obese and insulin-resistant subjects, inducing the accumulation of metabolic anomalies within these individuals, including autoimmune and inflammatory diseases. Thus, adipokines are an interesting drug target to treat autoimmune diseases, obesity, insulin resistance, and adipose tissue inflammation. …”
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