Construction of a circRNA-miRNA-mRNA Regulatory Network for Coronary Artery Disease by Bioinformatics Analysis by Zebo Zhang, Haiyan Qian, Li Wang, Zhenbo Tao, Keai Cheng, Kaiyue Wang, Yanqing Xie, Lina Zhang

“…Functional enrichment analysis showed that DEmRNAs were significantly involved in inflammation-related pathways and ubiquitin-protein ligase binding. …”
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Unveiling the molecular and cellular links between obstructive sleep apnea-hypopnea syndrome and vascular aging by Wei Liu, Le Zhang, Wenhui Liao, Huiguo Liu, Wukaiyang Liang, Jinhua Yan, Yi Huang, Tao Jiang, Qian Wang, Cuntai Zhang, Peifang Wei

“…This review examines the molecular and cellular features common to both OSAHS and VA, highlighting decreased melatonin secretion, impaired autophagy, increased apoptosis, increased inflammation and pyroptosis, increased oxidative stress, accelerated telomere shortening, accelerated stem cell depletion, metabolic disorders, imbalanced protein homeostasis, epigenetic alterations, and dysregulated neurohormonal signaling. …”
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It’s Like Doing Simultaneous Mind Puzzles: Exploring How Care is Understood and Experienced by Nursing Assistants Working in Sweden with Older Persons by Lilienthal A, Farias L, Boström AM, Patomella AH, Asaba E

“…Anneliese Lilienthal,1 Lisette Farias,1 Anne-Marie Boström,2– 4 Ann-Helen Patomella,1,5 Eric Asaba1,3,6 1Department of Neurobiology, Care Science and Society (NVS), Division of Occupational Therapy, Karolinska Institutet, Stockholm, Sweden; 2Department of Neurobiology, Care Science and Society (NVS), Division for Nursing, Karolinska Institutet, Stockholm, Sweden; 3Unit for Research, Education, Development and Innovation, Stockholms Sjukhem Foundation, Stockholm, Sweden; 4Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden; 5Academic Primary Health Care Centre (APC), Stockholm Region, Sweden; 6Department of Health and Rehabilitation, University of Gothenburg, Gothenburg, SwedenCorrespondence: Anneliese Lilienthal, Department of Neurobiology, Care Sciences, and Society, Division of Occupational Therapy, Karolinska Institutet, Huddinge, 141 83, Sweden, Email Anneliese.Lilienthal@ki.seBackground: The care of older persons is facing several challenges, especially as care tasks are becoming increasingly rationalized with less opportunity for relational engagement between nurse assistants and older persons. …”
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Gut Microbiota, Microinflammation, Metabolic Profile, and Zonulin Concentration in Obese and Normal Weight Subjects by Agnieszka Żak-Gołąb, Piotr Kocełak, Małgorzata Aptekorz, Maria Zientara, Łukasz Juszczyk, Gayane Martirosian, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz

“…The aim of the study is the assessment of plasma zonulin, haptoglobin and proinflammatory cytokines (TNF-α and IL-6) levels in relation to composition of gut microbiota in obese and normal weight subjects. Circulating inflammation markers, such as TNF-α, sTNFR1, sTNFR2, IL-6, zonulin, and haptoglobin levels were measured and semiquantitative analysis of gut microbiota composition was carried out in 50 obese and 30 normal weight subjects without concomitant diseases. …”
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Dietary index for gut microbiota and its protective role against kidney stones: evidence of diabetes as a mediator from NHANES cross-sectional data by Lei Wang, Junjun Wu, Ziwen Jiang, Chao Wang, Fuxiang Lin, Yuxiang Zhong, Pengpeng Zhao, Wei Wei, Jianhua Huang, Zhanping Xu

“…Mechanistically, DI-GM may reduce KS risk through gut microbial modulation of oxalate metabolism, urinary citrate excretion, and systemic inflammation.Conclusion and recommendationsHigher DI-GM scores are associated with reduced KS prevalence, partially mediated by diabetes. …”
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Severe Obesity in Women Can Lead to Worse Memory Function and Iron Dyshomeostasis Compared to Lower Grade Obesity by Jessica M. V. Pino, Vitória F. Silva, Marcos Mônico-Neto, Danielle C. Seva, Melissa Y. Kato, July N. Alves, Gabriela C. Pereira, Hanna Karen M. Antunes, Thales D. Galvao, Lia R. A. Bitterncourt, Sergio Tufik, Lysien I. Zambrano, Ana R. Dâmaso, Lila M. Oyama, David Thivel, Raquel M. S. Campos, Kil S. Lee

“…Insulin resistance, the abundance of advanced glycated end-products, and inflammation are some of the mechanisms associated with the lower cognitive performance observed in obesity. …”
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Evaluation of Retinal Structure and Optic Nerve Function Changes in Multiple Sclerosis: Longitudinal Study with 1-Year Follow-Up by Riwanti Estiasari, Adisresti Diwyacitta, Muhammad Sidik, Ni Nengah Rida Ariarini, Freddy Sitorus, Saraf Shafa Marwadhani, Kartika Maharani, Darma Imran, Reza Aditya Arpandy, David Pangeran, Manfaluthy Hakim

“…Multiple sclerosis (MS) is an autoimmune disease characterized by inflammation and demyelination of the central nervous system which often involves the optic nerve even though only 20% of the patients experience optic neuritis (ON). …”
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Copper Does Not Induce Tenogenic Differentiation but Promotes Migration and Increases Lysyl Oxidase Activity in Adipose-Derived Mesenchymal Stromal Cells by Marta Milewska, Anna Burdzińska, Katarzyna Zielniok, Katarzyna Siennicka, Sławomir Struzik, Piotr Zielenkiewicz, Leszek Pączek

“…Copper sulfate supplementation can have a beneficial effect on tendon regeneration not by inducing tenogenic differentiation, but by improving the recruitment of MSCs to the site of injury, where they can secrete growth factors, cytokines and chemokines, and prevent the effects of oxidative stress at the site of inflammation, as well as improve the stabilization of collagen fibers, thereby accelerating the process of tendon healing.…”
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L-shaped association of dietary inflammatory index (DII) and chronic diarrhea: results from NHANES 2005–2010 by Qing Zhao, Yue Xu, Xiangrui Li, Xiaotian Chen

“…Abstract Background Since diet is a known modulator of inflammation, the Dietary Inflammatory Index (DII), which quantifies the inflammatory potential of an individual’s diet, becomes a significant parameter to consider. …”
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Senegalin-2: A Novel Hexadecapeptide from <i>Kassina senegalensis</i> with Antibacterial and Muscle Relaxant Activities, and Its Derivative Senegalin-2BK as a Bradykinin Antagonist by Yueyang Lu, Yanguo Zhu, Chengbang Ma, Lei Wang, Mei Zhou, Tianbao Chen, Xiaonan Ma, Xu Zhang, Zhimin Fan

“…As a synthetically derived bradykinin antagonist and myotropic peptide with antibacterial properties, Senegalin-2BK shows promise in effective therapies for relieving pain, inflammation, and addressing muscular disorders such as urinary retention, constipation, and infections.…”
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Segmental analysis of human hair reveals intra-annual variation in 25(OH)D3 concentrations in modern and archaeological individuals by Kate Britton, Orsolya Czére, Eléa Gutierrez, Linda M. Reynard, Eamon Laird, Gary Duncan, Baukje de Roos

“…Abstract Vitamin D is essential for healthy skeletal growth and is increasingly recognised for its role in chronic disease development, inflammation and immunity. 25-hydroxyvitamin D3 (25(OH)D3) concentrations are an indicator of vitamin D status and are normally analysed in plasma or serum samples in clinical settings, while archaeological studies rely on the identification of skeletal markers of vitamin D deficiency, such as rickets. …”
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Nursing management of incontinence associated dermatitis complicated with fungal infection in a critically ill patient (1例危重症患者失禁性皮炎合并真菌感染的护理体会)... by ZHANG Ning (张宁), ZHANG Chunyan (张春艳), YUE Yuzi (岳玉姿), LIU Huan (刘欢), TANG Ling (唐玲), HAN Jianping (韩建萍), SUN Lei (孙磊), LI Ying (李影), ZHOU Jie (周洁)

“…The Traditional Chinese Medicine collapse stains method was used to relieve the pain and inflammation, and accelerate the wound healing. (本文总结 1 例危重症患者失禁性皮炎合并真菌感染的临床治疗及护理措施。…”
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Pancreatic resection with perioperative drug repurposing of propranolol and etodolac: trial protocol of the phase-II randomised placebo controlled PROSPER trial by Phillip Knebel, Thilo Hackert, Markus W Büchler, Ilse Rooman, Markus K Diener, Felix J Hüttner, André L Mihaljevic, Oliver Strobel, Gauthier Bouche, Johannes Hüsing

“…Therefore, a drug repurposing of betablockers and cyclooxygenase inhibitors seems reasonable to attenuate tumour-associated inflammation by inhibiting psychological, surgical and inflammatory stress responses. …”
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Signs and symptoms of vulvovaginal atrophy (VVA) in clinical practice – the possible involvement of thyroid autoimmunity in genitourinary syndrome of menopause (GSM) by Laura Cucinella, Federica Barbagallo, Mariacristina Erroi, Chiara Procaccianti, Ellis Martini, Lara Tiranini, Giorgia E. Parrotta, Greta Monne, Giulia M. Colombo, Aldo Calogero, Rossella E. Nappi

“…Women with thyroid ADs reported significantly higher scores for dryness, burning/itching, irritation/inflammation, and dyspareunia compared to those without it. …”
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Photo-curing hyaluronic acid-Janus antibacterial packs as O2 generator precisely modulate the infectious microenvironment for antibiotic-free periodontal therapy by Runxiu Wei, Gaojie Li, Yuying Huang, Linjing Mi, Jiamin Wu, Huan Huang, Na Yin, Yuling Chen, Qiang Yang, Wenjun Zhang, Bingzhi Sun, Ran Sun, Ling Guo, Min Feng

“…Notably, animal experiments confirmed that H-Janus antibacterial packs markedly improved the clinical scores in rats with periodontitis by inhibiting bacterial growth, alleviating inflammation, and fostering the regeneration of periodontal tissues. …”
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MiR-155-Mediated Deregulation of GPER1 Plays an Important Role in the Gender Differences Related to Inflammatory Bowel Disease by Xiaojuan Shao, Jintao Li, Fumin Xu, Dongfeng Chen, Kaijun Liu

“…Furthermore, the male miR-155−/− mice showed increased inflammation compared to the female miR-155−/− mice in the above aspects. …”
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Efficacy of Curcumin on Treating Cancer Anorexia-Cachexia Syndrome in Locally or Advanced Head and Neck Cancer: A Double-Blind, Placebo-Controlled Randomised Phase IIa Trial (CurCh... by Tawasapon Thambamroong, Kasan Seetalarom, Siriwimon Saichaemchan, Yanisa Pumsutas, Naiyarat Prasongsook

“…CAS causes increased energy expenditure by increasing systemic inflammation and decreasing energy consumption due to anorexia. …”
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A rare intersection: squamous cell carcinoma of the tonsil and the anti-TIF1 syndrome masquerade by Manush Sondhi, Megan Lear, Saleha Dar, Madiha Tariq

“…Mechanisms connecting TIF1 dermatomyositis and cancer involve gene expression dysregulation and chronic inflammation. Anti-TIF1 antibodies are key biomarkers, with IgG2 isotype levels highly predictive of cancer risk. …”
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Alginate-based encapsulation of porcine placenta extract: Preparation, enteric sustained release, biological activities, and stability by Anukul Taweechaipaisankul, Nutthanit Thumrongsiri, Walailuk Chonniyom, Paweena Dana, Prattana Tanyapanyachon, Monthira Rattanatayarom, Wannapa Chinchoosak, Nattika Saengkrit

“…Moreover, the anti-inflammation effect was monitored via the reduction in the levels of cytokines, including IL-6, IL-8, and TNF-α. …”
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T-Cell Subpopulations and Differentiation Bias in Diabetic and Non-Diabetic Patients with Chronic Kidney Disease by Ana Cecilia Granda Alacote, Gabriela Goyoneche Linares, María Gracia Castañeda Torrico, Daysi Zulema Diaz-Obregón, Michael Bryant Castro Núñez, Alexis Germán Murillo Carrasco, Cesar Liendo Liendo, Katherine Susan Rufasto Goche, Víctor Arrunátegui Correa, Joel de León Delgado

“…Background: Chronic kidney disease (CKD) patients often experience dysregulated inflammation, particularly when compounded by comorbidities such as type 2 diabetes (T2D). …”
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