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7521
Identification of blood transcriptome modules associated with suicidal ideation in patients with major depressive disorder
Published 2025-01-01“…Our findings highlight that gene expression regulation, immune response, and inflammation may be linked to SI in patients with MDD, while pathways associated with innate immunity, energy metabolism, mitochondrial function, and neurodegeneration appear to be more broadly related to MDD.…”
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7522
Effect of N-Feruloylserotonin and Methotrexate on Severity of Experimental Arthritis and on Messenger RNA Expression of Key Proinflammatory Markers in Liver
Published 2016-01-01“…Administration of either N-f-5HT or MTX caused reduction of inflammation measured as the level of CRP in plasma and the activity of LOX in the liver. mRNA transcription of TNF-α and iNOS in the liver was significantly attenuated in both MTX and N-f-5HT treated groups of arthritic rats. …”
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7523
The relationship between serum vitamin C levels and high-sensitivity C-reactive protein in children
Published 2024-12-01“…Abstract The relationship between vitamin C nutritional status and inflammation has garnered increasing attention, but studies in younger populations are limited. …”
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7524
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7525
Hyaluronic acid-curcumin nanoparticles for preventing the progression of experimental autoimmune uveitis through the Keap1/Nrf2/HO-1 signaling pathway
Published 2025-02-01“…Excessive autoimmune inflammation and oxidative stress are major drivers that contribute to the initiation and progression of uveitis. …”
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7526
Th2 Regulation of Viral Myocarditis in Mice: Different Roles for TLR3 versus TRIF in Progression to Chronic Disease
Published 2012-01-01“…Viral infections are able to induce autoimmune inflammation in the heart. Here, we investigated the role of virus-activated Toll-like receptor (TLR)3 and its adaptor TRIF on the development of autoimmune coxsackievirus B3 (CVB3) myocarditis in mice. …”
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7527
Linking evidence for targeted blood biomarkers in post-stroke cognitive impairment and dementia
Published 2025-01-01“…In this framework, blood biomarkers are divided into broad pathologic categories including inflammation, neurodegeneration, neuroaxonal injury, and vascular injury. …”
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7528
Establishment of the fingerprint of ganoderma lucidum spore powder and study on the anti-inflammatory activity of ganoderma lucidum spore oil
Published 2025-01-01“…[Conclusion] Ganoderma lucidum spore oil is used to reduce the inflammation of the body by inhibiting the release of inflammatory factors to achieve the protective effect on immune cells. …”
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7529
Hybrid Nanocomposite Mini-Tablet to Be Applied into the Post-Extraction Socket: Matching the Potentialities of Resveratrol-Loaded Lipid Nanoparticles and Hydroxyapatite to Promote...
Published 2025-01-01“…<b>Background/Objectives</b>: Following tooth extraction, resveratrol (RSV) can support healing by reducing inflammation and microbial risks, though its poor solubility limits its effectiveness. …”
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7530
The extract of the immature fruit of Poncirus trifoliata induces apoptosis in colorectal cancer cells via mitochondrial autophagy
Published 2020-09-01“…The immature fruits of Poncirus trifoliate are used as a medicine for the treatment of gastrointestinal disorders, inflammation, and allergies in East Asia. However, their effect on colon cancer cells remains unclear. …”
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7531
Electrocardiographic Frontal QRS-T Angle Is Independently Associated with the Presence of Celiac Disease and Disease Duration
Published 2025-01-01“…<b>Conclusions:</b> In this study, we demonstrated that chronic inflammation secondary to CD may have negative effects on cardiac repolarization and that this effect is closely related to disease duration.…”
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7532
Comparative Analysis of miRNA Expression Profiles of Yak Milk-Derived Exosomes at Different Altitudes
Published 2025-01-01“…These miRNAs were found to be implicated in pathways associated with mammary gland inflammation, virus infection regulation, and heat stress response. …”
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7533
Macular edema after retinal vein occlusions. Macular morphometry and chorioretinal hemodynamics
Published 2021-09-01“…The major cause of vision loss in RVOs is macular edema which results from subclinical inflammation characterized by leukostasis and enhanced expression of adhesion molecules and production of cytokines increasing retinal capillary permeability. …”
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7534
The Utility of Synovial Fluid Interleukin-10 in Diagnosing Chronic Periprosthetic Joint Infection: A Prospective Cohort Study
Published 2025-01-01“…Synovial fluid interleukin-10 (SF IL-10), an anti-inflammatory cytokine produced by leukocytes, plays a pivotal role in inflammation and infection regulation. However, limited research has explored the diagnostic potential of SF IL-10 in chronic PJI patients.Objective: The study aimed to investigate the relationship between SF IL-10 and incidence of chronic PIJ, and to evaluate its diagnostic reliability.Design and Methods: We analyzed data from 137 patients who underwent revision surgery for aseptic loosening or chronic PJI between 2017 and 2019 in our hospital. …”
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7535
Butterfly Pea and Roselle Combination Extracts Reduce V-CAM, ICAM, and IL-6 Levels in High Fat Atherogenic Diet Rats
Published 2024-12-01“…BACKGROUND: Atherosclerosis, driven by inflammation and oxidative stress, increases the risk of coronary heart disease (CHD). …”
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7536
Treatment of Miller I Mandibular Gingival Recessions Using PRF vs. Connective Graft
Published 2021-01-01“…GR, KT, VSTT, extraoral inflammation (EI), and patient discomfort (PaD) were assessed at 45 days. …”
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7537
Superoxide dismutase promotes gastric tumorigenesis mediated by Helicobacter pylori and enhances resistance to 5-fluorouracil in gastric cancer
Published 2025-02-01“…We explored the molecular mechanisms of links between H. pylori, inflammation, and SOD2 in GC. We found that SOD2 was upregulated in GC. …”
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7538
Chitosan oligosaccharide alleviates DON-induced liver injury via suppressing ferroptosis in mice
Published 2025-01-01“…In summary, this research showed that COS mitigated DON-induced liver injury in mice by alleviating DON-induced oxidative stress, inflammation, apoptosis, and ferroptosis via modulating the Nrf2/HO-1/NF-κB and GPX4 signaling pathways. …”
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7539
The combined effects of cardiometabolic index and high-sensitivity C-reactive protein on the risk of new onset stroke in a Chinese national prospective longitudinal cohort study
Published 2025-01-01“…Since obesity, lipid metabolism, and inflammation may collectively facilitate the occurrence of stroke, we hypothesize that a combination of elevated levels of the CMI and high-sensitivity C-reactive protein (hs-CRP) increases the risk of future stroke among middle-aged and older Chinese adults. …”
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7540
Comparison of the Effects of Mesenchymal Stem Cells with Their Extracellular Vesicles on the Treatment of Kidney Damage Induced by Chronic Renal Artery Stenosis
Published 2020-01-01“…In this study, we compared the effects of adipose-derived MSCs (ASCs) with those of the MVs and EXs released by ASCs on tissue inflammation and renal function in 2 K-1C rats. Results. …”
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