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7241
Impact of parathyroidectomy on inflammatory and cardiovascular risk parameters in primary hyperparathyroidism: a retrospective analysis
Published 2025-02-01“…Multivariable regression analysis demonstrated that postoperative PTH levels were significantly associated with calcium (B = 39.82, Beta = 0.321, p = 0.0469), NLR (B = 110.02, Beta = 0.428, p = 0.0384), baseline comorbidity scores (B = -30.54, Beta = -0.287, p = 0.0361), and preoperative inflammation levels (B = 25.69, Beta = 0.311, p = 0.0386). …”
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7242
Distinct subcellular localization of tau and alpha-synuclein in lewy body disease
Published 2025-01-01“…Immunofluorescence for major-histocompatibility complex class 2 (MHCII) and ionized calcium binding adaptor molecule 1 (Iba1) also was performed because inflammation is an additional pathological hallmark of LBDs, and they were a positive control for two markers known to colocalize. …”
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7243
An analysis of heavy silicone oil treatment for inferior proliferative vitreoretinopathy
Published 2025-01-01“…Complications were classified into major categories relating to intraocular pressure, inflammation, lens, and oil emulsification/migration. …”
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7244
Interaction of norsecurinine-type monomeric and dimeric alkaloids with α-tubulin: a molecular docking study
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7245
Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barrier in AP...
Published 2025-02-01“…These changes were reversed by MA and probiotics.ConclusionMA can significantly reduce intestinal inflammation and alleviate destruction of the intestinal mucosal barrier in APP/PS1 mice. …”
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7246
Biochemistry of the Thrombin-Like TLBpic and Its Purification from Bothrops pictus “Jergon de la Costa” (Reptilia: Viperidae)
Published 2019-01-01“…The venom of snakes is composed of a heterogeneous mixture of simple and complex substances, with inflammation and hyperalgesia being the first symptom caused by the action of Bothrops venom, generating processes such as leukocyte infiltration, hemorrhage, and the intravascular formation of thrombi. …”
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7247
Modulatory Effect of 1,25-Dihydroxyvitamin D3 on IL1β-Induced RANKL, OPG, TNFα, and IL-6 Expression in Human Rheumatoid Synoviocyte MH7A
Published 2013-01-01“…In summary, although it has a biological function to induce RANKL expression, 1,25(OH)2D3 could upregulate OPG/RANKL ratio and mediate anti-inflammatory action in an inflammatory milieu of synoviocyte, contributing to the inhibition of inflammation-induced osteoclastogenesis in RA.…”
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7248
Correlation between MDA Level and Chitotriosidase-1 Activity in Seminal Fluid of Iraqi Infertile Males
Published 2024-12-01“…The notable chitinase in humans plays a significant role in the body's immunological response and is linked to inflammation, infection, tissue damage, and remodeling processes. …”
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7249
Molecular mechanisms and therapeutic strategies of Naegleria fowleri Carter (1970): a review of the fatal brain-eating amoeba
Published 2024-05-01“…In the brain, the amoeba causes extensive tissue necrosis, haemorrhage, and inflammation, leading to severe neurological symptoms and death within days. …”
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7250
Unveiling molecular insights: in silico exploration of TLR4 antagonist for management of dry eye syndrome
Published 2024-05-01“…It is identified by the excessive buildup of reactive oxygen species, leading to substantial corneal epithelial cell demise and ocular surface inflammation attributed to TLR4. In this study, we aimed to identify potential compounds to treat of dry eye syndrome by exploring in silico methods.Methods In this research, molecular docking and dynamics simulation tests were used to examine the effects of selected compounds on TLR4 receptor. …”
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7251
M2 Macrophages as a Potential Target for Antiatherosclerosis Treatment
Published 2019-01-01“…Atherosclerosis is a chronic progressive inflammation course, which could induce life-threatening diseases such as stroke and myocardial infarction. …”
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7252
Eosinophilic Asthma Secondary to Adjuvant Anti-PD-1 Immune Checkpoint Inhibitor Treatment in a Melanoma Patient
Published 2022-01-01“…FeNO was raised at 129 indicating inflammation of his airways, and peak flow was 422 l/min. …”
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7253
COVID-19 encephalopathy with severe neurological symptoms: a clinical case presentation with literature review
Published 2023-10-01“…However, the most likely etiology of encephalopathy is multifactorial: systemic disease response, inflammation, coagulopathy, direct viral neuroinvasion, endoartheritis, and possibly post-infectious autoimmune mechanisms. …”
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7254
Deciphering of differences in gut microbiota and plasma metabolites profile between non-obese and obese Golden Retrievers dogs
Published 2025-01-01“…IntroductionGolden Retrievers have a high risk of obesity, which is prevalent in dogs and is associated with inflammation and cancer, impairing the health and life expectancy of companion animals. …”
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7255
Type 2 Cytokine–Dependent Skin Barrier Regulation in Personalized 2-Dimensional and 3-Dimensional Skin Models of Atopic Dermatitis: A Pilot Study
Published 2025-01-01“…Taken together, our pilot study suggests that hair follicle–derived KCs from patients with AD represent a useful model system to study AD-related inflammation in a personalized in vitro model.…”
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7256
Modulation of Cognition: The Role of Gnidia glauca on Spatial Learning and Memory Retention in High-Fat Diet-Induced Obese Rats
Published 2019-01-01“…The positive influences on cognitive functions might be attributed to the extracts’ phytochemicals that have been suggested to confer protection against obesity-induced oxidative damage, reduction of central inflammation, and increased neurogenesis. The therapeutic effects observed suggest that Gnidia glauca might be an alternative to current medications for the symptomatic complications of obesity, such as learning and memory loss. …”
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7257
Serum PCSK9 Correlates with PTX3 and Apolipoproteins B, A1, and C3 Concentrations in Patients with Type 2 Diabetes
Published 2021-01-01“…Our results indicate that circulating PCSK9 is significantly associated with inflammation marker PTX3 as well as atherogenic lipids and apolipoproteins C3, B100, and B48, which might be of value in understanding interactions between development of atherosclerosis and inflammatory state in DM2 patients.…”
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7258
Lasers in Esthetic Dentistry: Soft Tissue Photobiomodulation, Hard Tissue Decontamination, and Ceramics Conditioning
Published 2014-01-01“…Low power lasers act at cellular level leading to pain reduction, modulation of inflammation, and improvement of tissue healing. High power lasers act by increasing temperature and have the potential to promote microbial reduction and ablation of hard and soft tissues. …”
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7259
Pathogenetic Substantiation of the Therapeutic Impact on Microbiota in Irritable Bowel Syndrome
Published 2019-09-01“…The development of a lowactivity inflammation in IBS can partly be explained by the increased interaction of flagellin with the corresponding receptor, as well as the influx of excess bacteria from the small intestine. …”
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7260
Non-alcoholic fatty liver disease: comparative assessment of diagnostic and treatment approaches in the Russian Federation and People’s Republic of China
Published 2018-08-01“…Results of clinical efficacy estimation of the new drug Bicyclol in the Russian market, that it was developed in the People’s Republic of China demonstrate reduction of severity of inflammation, steatosis, fibrosis and decrease of NAFLD activity scores.…”
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