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7201
Patient‐Reported Fatigue Associated with Joint Histopathology in Rheumatoid Arthritis
Published 2025-01-01“…SLH was affected by synovial lymphocytic inflammation. In multivariable models, female sex, DAS28‐ESR, and SLH were all associated with higher fatigue. …”
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7202
A narrative review about cognitive impairment in Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD): Another matter to face through a holistic approach
Published 2025-02-01“…Indeed, cognitive decline in MASLD translates in low concentration and processing speed, reduced memory, sleepiness but also anxiety and depression. Chronic systemic inflammation, hyperammonemia, genetic background and intestinal dysbiosis possibly contribute to the cognitive decline in MASLD patients. …”
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7203
Role of acute respiratory diseases in pathogenesis of distal limb infections in cattle
Published 2021-08-01“…Low molecular weight circulating immune complexes settle in various organs and tissues of the body, lead to inflammation and damage the normal tissue structure. …”
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7204
<i>Aspergillus oryzae</i> Fermented <i>Plumula Nelumbinis</i> Against Atopic Dermatitis Through AKT/mTOR and Jun Pathways
Published 2024-12-01“…Moreover, FPN can also alleviate SDS-induced inflammation in zebrafish. It is also found that the anti-inflammatory activity of <i>Plumula Nelumbinis</i> was enhanced by <i>Aspergillus oryzae</i> fermentation, and the oil phase of the fermentation product showed better activity, which may be due to microbial fermentation changing the structure of the original alkaloids. …”
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7205
Associations between White Blood Cell Count and the Development of Incidental Nonalcoholic Fatty Liver Disease
Published 2016-01-01“…Chronic low-grade inflammation is thought to be associated with the pathogenesis of nonalcoholic fatty liver disease (NAFLD). …”
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7206
From gut to liver: Exploring the crosstalk between gut-liver axis and oxidative stress in metabolic dysfunction-associated steatotic liver disease
Published 2025-01-01“…Our analysis reveals several key findings: (1) Bile acid dysregulation can trigger oxidative stress through enhanced ROS production in hepatocytes and Kupffer cells, leading to mitochondrial dysfunction and lipid peroxidation; (2) Gut microbiota dysbiosis disrupts intestinal barrier function, allowing increased translocation of endotoxins like LPS, which activate inflammatory pathways through TLR4 signaling and promote oxidative stress via NADPH oxidase activation; (3) The redox-sensitive transcription factors NF-κB and Nrf2 serve as crucial mediators in the gut-liver axis, with NF-κB regulating inflammatory responses and Nrf2 orchestrating antioxidant defenses; (4) Oxidative stress-induced damage to intestinal barrier function creates a destructive feedback loop, further exacerbating liver inflammation and disease progression. These findings highlight the complex interrelationship between gut-liver axis dysfunction and oxidative stress in MASLD pathogenesis, suggesting potential therapeutic targets for disease management.…”
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7207
Impaired Growth during Childhood in Patients with Primary Ciliary Dyskinesia
Published 2013-01-01“…Primary ciliary dyskinesia (PCD) leads to recurrent/chronic respiratory infections, resulting in chronic inflammation and potentially in chronic pulmonary disease with bronchiectasis. …”
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7208
Platelet-rich fibrin and silver nano-particles loaded chitosan treatment for post- laminectomy epidural scar adhesions: in vivo rats study model
Published 2025-02-01“…Results Data revealed that epidural scar adhesion, scaring, arachnoid involvement, dural thickness, as well as inflammation and TGFβ-1and IL-6 coding genes expression were significantly reduced in PRF group, Chi/Ag-NPs group, and combined group compared to the laminectomy group. …”
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7209
Current advances on the phytochemistry, pharmacology, quality control and applications of Anoectochilus roxburghii
Published 2025-01-01“…Pharmacological studies further demonstrated its activities, containing anti-inflammation, anti-oxidation, and antihyperlipidemia effects. …”
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7210
Difference in the Vitreal Protein Profiles of Patients with Proliferative Diabetic Retinopathy with and without Intravitreal Conbercept Injection
Published 2018-01-01“…In addition to decreasing the intravitreal vascular endothelial growth factor level, IVC may alter the vitreal protein profile in patients with PDR, with the differentially regulated proteins involved in the immune response, platelet degranulation, complement activation, and inflammation.…”
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7211
Salivary microbiota dysbiosis and elevated polyamine levels contribute to the severity of periodontal disease
Published 2025-01-01“…The bacteriome in the oral cavity plays a pivotal role in promoting the health and well-being of human beings. Gingivitis, an inflammation of the gingival tissue, arises due to plaque accumulation on the teeth, often leads to periodontitis. …”
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7212
Unraveling ankylosing spondylitis: Exploring the genetic and immunological factors and latest treatment innovations
Published 2025-01-01“…Over 100 genes related to AS were identified in genome-wide association studies, many connected to IL-23-driven inflammation and antigen processing. AS is regulated by various immunological cells, and changes in bone structure are caused by the interaction of immune cells with bone cells. …”
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7213
Long-Term Surgical Outcomes of Glaucoma Drainage Implants in Eyes with Preoperative Intraocular Pressure Less than 19 mmHg
Published 2024-01-01“…Postop complications (23.9%) included GDI exposure (7.5%), inflammation (4.5%), shallow anterior chamber (4.5%), and strabismus (1.5%). …”
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7214
Is oxidative stress - antioxidants imbalance the physiopathogenic core in pediatric obesity?
Published 2024-08-01“…In addition to these, and in the light of the recent COVID-19 pandemic, the role played by oxidative stress in the induction, maintenance and potentiation of chronic inflammation among overweight children and adolescents becomes a topic of interest again. …”
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7215
Silica Nanoparticles Loaded With Selenium Quantum Dots Reduce Myocardial Ischemia-Reperfusion Injury by Alleviating Ferroptosis and Mitochondrial Dysfunction
Published 2025-02-01“…These effects collectively resulted in reduced myocardial loss, inflammation, and fibrosis following IR injury. Compared to PSN alone, Se@PSN showed superior therapeutic efficacy against IR injury.Conclusion: Se@PSN exhibit great potential in reducing ferroptosis and protecting mitochondrial function, making them a promising therapeutic approach for the treatment of myocardial IR injury. …”
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7216
Efficacy of oral irrigators compared to other interdental aids for managing peri-implant diseases: a systematic review
Published 2025-01-01“…Conclusion Oral irrigators along with toothbrushing were found to be more effective in removing microbial plaque around implants and controlling peri-implant inflammation compared to mechanical brushing alone. The reduction in BOP was better with the use of oral irrigation compared to floss and interdental brush.…”
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7217
Overweight, Obesity, and Neighborhood Characteristics among Postpartum Latinas
Published 2013-01-01“…Madres para la Salud (Mothers for Health) is a 12-month prospective, randomized controlled trial exploring a social support intervention with moderate-intensity physical activity to effect changes in body fat, systemic and fat tissue inflammation, and depression symptoms in sedentary postpartum Latinas. …”
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7218
Oxidative stress in diabetes mellitus and its complications: From pathophysiology to therapeutic strategies
Published 2025-01-01“…Oxidative stress plays a significant role in the onset of diabetes and its associated complications by impairing insulin production, increasing insulin resistance, maintaining hyperglycemic memory, and inducing systemic inflammation. A more profound comprehension of the molecular processes that link oxidative stress to diabetes is crucial to new preventive and therapeutic strategies. …”
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7219
Limosilactobacillus mucosae FZJTZ26M3 prevents NAFLD in mice through modulation of lipid metabolism and gut microbiota dysbiosis
Published 2024-05-01“…Furthermore, the results of 16S rRNA gene sequencing revealed a drop in the relative abundance of Ruminococcaceae, which is linked to inflammation, but the relative abundance of a potential probiotic Akkermansia significantly increased after L. mucosae FZJTZ26M3 intervention. …”
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7220
Impaired mobility drives disability in psoriatic arthritis – An observational study from Karnataka Psoriatic Arthritis Cohort (KPsAC)
Published 2023-01-01“…Nearly half of the cohort had mild-to-moderate disability suggesting a high burden of inflammation. Higher joint activity scores are strongly associated with disability.…”
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