The inflammatory markers combined with CA125 may predict postoperative survival in endometrial cancer by Hongxing Lin, Wenhui Zhong, Liying Zhong, Chengwen Que, Xiaosong Lin

“…Differences in each index at different EC stages and the correlation between the index and EC stage were analysed, and the influence of the index on EC prognosis was evaluated.Results Platelet distribution width (PDW) levels were significantly lower in patients with advanced EC than in those with early EC, whereas the systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), and CA125 levels were significantly higher in patients with advanced EC (all P < 0.05). …”
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Association of Baseline Neutrophil-to-Lymphocyte Ratio with Clinicopathological Characteristics of Papillary Thyroid Carcinoma by Dimitrios K. Manatakis, Sofia Tseleni-Balafouta, Dimitrios Balalis, Vasiliki N. Soulou, Dimitrios P. Korkolis, George H. Sakorafas, Georgios Plataniotis, Emmanouil Gontikakis

“…Conclusions. As an index of inflammation, NLR is inexpensive, readily available, and easy to extract from routine blood tests. …”
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Small Bowel Endoscopy Diagnostic Yield and Reasons of Obscure GI Bleeding in Chinese Patients by Ya-Fei He, Ning-Bo Hao, Wu-Chen Yang, Li Yang, Zhong-Li Liao, Chao-Qiang Fan, Jin Yu, Jian-Ying Bai, Shi-Ming Yang, Hong Guo

“…A lesion that was believed to be the source of the bleeding (ulceration, mass lesion, vascular lesion, visible blood, inflammation, or others) was considered to be a positive finding. …”
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Aqueous Extract of Leaves and Flowers of Acmella caulirhiza Reduces the Proliferation of Cancer Cells by Underexpressing Some Genes and Activating Caspase-3 by Huiny Miriane Tienoue Fotso, Mary-Ann Mbong Angie, Françoise Raïssa Ntentie, Inelle Makamwe, Ferdinand Lanvin Edoun Ebouel, Emmerencia Kenjing Ndansack, Enyong Julius Oben

“…Results also showed that AE-Ac downregulated the expression of inflammation (IL-1b p=0.017 and IL-6 p=0.028), growth factors (PDGF p=0.039, IGF p=0.034, E2F1p=0.038, and E2F2p=0.016), and antiapoptotic protein genes (Bcl-2 p=0.028 and Bcl-6 p=0.039). …”
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Markedly Increased High-Mobility Group Box 1 Protein in a Patient with Small-for-Size Syndrome by Darren G. Craig, Patricia Lee, E. Anne Pryde, Ernest Hidalgo, Peter C. Hayes, Stephen J. Wigmore, Stuart J. Forbes, Kenneth J. Simpson

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Increased Frequency of CD4+ CD25+ FoxP3+ T Regulatory Cells in Pulmonary Tuberculosis Patients Undergoing Specific Treatment and Its Relationship with Their Immune-Endocrine Profil... by Ariana Díaz, Natalia Santucci, Bettina Bongiovanni, Luciano D’Attilio, Claudia Massoni, Susana Lioi, Stella Radcliffe, Griselda Dídoli, Oscar Bottasso, María Luisa Bay

“…Lowered levels of proinflammatory cytokines together with an increased frequency of Tregs of patients undergoing specific treatment might reflect a downmodulatory effect of these cells on the accompanying inflammation.…”
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Dissecting the Molecular Mechanism of Wang-Bi Capsule in the Treatment of Experimental Rheumatoid Arthritis Based on Synovial Tissue Proteomic Analysis by Haiyang Shu, Yingjie Shi, Li Li, Ning Zhao, Cheng Lu, Aiping Lu, Xiaojuan He

“…Furthermore, the proteomic analysis of synovial tissue showed that WB could regulate several signaling pathways associated with inflammation or cell migration, such as “IL-1 signaling,” “IL-8 signaling,” and “CXCR4 signaling.” …”
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Efficacy of Inhaled Steroid Over Systemic Steroid in Stabilizing Acute Asthma in Emergency Room by B.V. Siva Vara Prasad Rao, Santhosh K B, Anil Sankol S M

“…Glucocorticoids are good anti-inflammatory agents, effective at treating asthma and decreasing inflammation of the airways. Although systemic use of steroids is commonly being used, inhaled steroids could be also beneficial in acute asthma. …”
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Next-generation sequencing and immuno-informatics for designing a multi-epitope vaccine against HSV-1-induced uveitis by He Cao, Zhi Cao, Yue Han, Jing Shan

“…BackgroundUveitis, characterized by intraocular inflammation, poses significant clinical challenges, often leading to vision impairment or blindness. …”
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Investigating the Effect of 8 Weeks of Endurance Training on the Levels of Inflammatory Markers (IL-6/TNF-α) and Some Metabolic Parameters in Male Rats with Nonalcoholic Fatty Live... by Vahid Kazemizadeh, Amirabbas Monazzami, Fakhredin Saba, Andrew J McAinch

“…Introduction: This study aimed to analyze the effects of endurance training (Aerobic) on the levels of inflammatory markers (IL-6/TNF-α) and some metabolic parameters in male rats with non-alcoholic fatty liver disease to investigate the feasibility of using exercise training to reduce inflammation. Material and Methods: A total of 44 Wistar rats were randomly assigned into two groups: (I) standard diet group of 22 rats and (II) high-fat diet group with 22 rats supplemented with free access to fructose water. …”
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Involvement of Toll -like receptor 9 signaling in neutrophil extracellular traps-induced epithelial-to-mesenchymal transition in myositis-associated interstitial lung disease by Feng Yingyue, Zhuo Cui, Su Qiyan, Cui Xi, Guo Jin, Zhu Jiarui, Zhang Sigong

“…Moreover, NETs upregulated genes associated with inflammation and fibrosis. Notably, TLR9 gene expression was significantly elevated, and the use of a TLR9 inhibitor alleviated EMT. …”
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Ultrasonographic evaluation of joint involvement in rheumatoid arthritis: Comparison with conventional radiography and correlation with disease activity parameters by Renu Saigal, Laxmikant Goyal, Hariram Maharia, Meenakshi Sharma, Abhishek Agrawal

“…Conclusions: US detected CFS which an indicator of ongoing inflammation in RA patients with clinical remission (DAS28 <2.6). …”
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The Immunosuppressant Fingolimod (FTY720) for the Treatment of Mechanical Force-Induced Abnormal Scars by Masayo Aoki, Akatsuki Kondo, Noriko Matsunaga, Azusa Honda, Yuri Okubo, Kazuaki Takabe, Rei Ogawa

“…Abnormal scars such as hypertrophic scars (HSs) and keloids are excessively growing scars that exhibit chronic inflammation and capillary vasculogenesis. The lipid mediator sphingosine-1-phosphate (S1P) is important in inflammatory cell recruitment and angiogenesis. …”
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EXamining the feasibility of exerCisE to manage symptoms of Lupus (EXCEL): a protocol for a randomised controlled pilot study by John Reynolds, Katie Hesketh, Matthew Cocks, Megan Quickfall, Alex J Wadley, Scott Green, Jet Veldhuijzen Van Zanten

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Immunopathological Changes of Streptococcus pneumoniae Causing Respiratory Infection in Lambs by Abbas A Hamzah, Zainab I Ibrahim

“…Histopathologically, severe erosion and necrosis in the trachea and bronchus epithelium, along with inflammation in adjacent mucosa and submucosa, accompanied by focal inflammatory infiltration and emphysema in the lung by day 6 post-exposure, were observed. …”
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Role of antimicrobial photodynamic therapy for the management of peri‑implant diseases among habitual nicotinic product users: A systematic review by Abdulrahman M. AlMubarak

“…Conclusion: In the short term, a single session of aPDT as an adjunct to MD effectively reduces peri‑implant soft-tissue inflammation among NP users with peri‑implant diseases. …”
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Vitamin B12 and diabetic neuropathies by V.A. Serhiyenko, M.-Y. Markevych, V.B. Sehin, A.A. Serhiyenko

“…Most studies have identified the contribution of low-grade chronic inflammation (LGCI) and oxidative stress (OS) to the development of DN. …”
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Beneficial Effects of Ursodeoxycholic Acid on Metabolic Parameters and Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blind, Placebo-Controlled Cli... by Biljana Lakić, Ranko Škrbić, Snežana Uletilović, Nebojša Mandić-Kovačević, Milkica Grabež, Mirna Popović Šarić, Miloš P. Stojiljković, Ivan Soldatović, Zorica Janjetović, Anastasija Stokanović, Nataša Stojaković, Momir Mikov

“…Oxidative stress and inflammation are closely related pathophysiological processes, both occurring in type 2 diabetes mellitus (T2DM). …”
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Plasma Chemerin Levels Are Increased in ST Elevation Myocardial Infarction Patients with High Thrombus Burden by Ahmet Hakan Ateş, Uğur Arslan, Aytekin Aksakal, Ahmet Yanık, Metin Özdemir, Selim Kul

“…Results from our study have demonstrated for the first time that chemerin levels were higher in STEMI patients with greater thrombus burden and higher level of inflammation.…”
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A patient-based iPSC-derived hepatocyte model of alcohol-associated cirrhosis reveals bioenergetic insights into disease pathogenesis by Bani Mukhopadhyay, Cheryl Marietta, Pei-Hong Shen, Abdul Oiseni, Faridoddin Mirshahi, Maria Mazzu, Colin Hodgkinson, Eli Winkler, Qiaoping Yuan, Daniel Miranda, George Kunos, Arun J. Sanyal, David Goldman

“…While differences in metabolism, inflammation, signaling, microbiome signatures and genetic variations have been tied to the pathogenesis of AC, the key underlying mechanisms for this interindividual variability, remain to be fully elucidated. …”
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