Exploring the Molecular Modalities in the Pathogenesis of Diabetic Kidney Disease with a Focus on the Potential Therapeutic Implications by Lyubomir Gaydarski, Kristina Petrova, Ivan Angushev, Stancho Stanchev, Alexandar Iliev, Nikola Stamenov, Vidin Kirkov, Boycho Landzhov

“…The NO/NOS system, integral to vascular and renal homeostasis, also exhibits altered activity in DKD, with reduced bioavailability linked to oxidative stress and inflammation. This review underscores the intricate interplay between these pathways in DKD, revealing both challenges and opportunities in their therapeutic targeting. …”
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Serum Prohepcidin Levels Are Lower in Patients with Atrophic Gastritis by Hyung-Keun Kim, Eun-Chul Jang, Ju-Ok Yeom, Sun-Young Kim, Hyunjung Cho, Sung Soo Kim, Hiun-Suk Chae, Young-Seok Cho

“…Hepcidin, an iron regulatory hormone, is increased in response to inflammation and some infections. We investigated the relationships among serum prohepcidin, iron status, Helicobacter pylori infection status, and the presence of gastric mucosal atrophy. …”
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Misdiagnosis of Leprosy with Severe Reversal Reaction as Psoriatic Arthritis: A Case Report and Literature Review by Gunawan H, Hidayah RMN, Ruchiatan K, Pangastuti M, Usman HA, Amalia F

“…Meanwhile, leprosy reactions are immunologically mediated episodes of acute or subacute inflammation that occur during the chronic course of the disease. …”
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Effect of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Biomarkers of Kidney Injury and Vascular Calcification in Diabetic Kidney Disease: A Randomized Controlled Trial by Thananda Trakarnvanich, Bancha Satirapoj, Swangjit Suraamornkul, Thanit Chirananthavat, Anoma Sanpatchayapong, Torpong Claimon

“…Dipeptidyl peptidase-4 (DPP-4) inhibitors improve glycemic control and have pleiotropic effects on kidney injury, albuminuria, and vascular inflammation, especially in animal models. We evaluated the effects of a potent DPP4 inhibitor (gemigliptin) on these processes among patients with diabetic kidney disease (DKD). …”
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The Role of Prolactin as a Disease Activity Indicator in Some Rheumatic Diseases by Mohamed Ismail Abdelkarem, HM Fayed, Wael Abd El-Mohsen Abady, Eman Abulhagag Mohammed Mahmoud

“…Background: Autoimmune rheumatic diseases, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and scleroderma, predominantly affect women and are characterized by systemic inflammation, leading to organ failure. Prolactin (PRL), a hormone produced by the pituitary gland and lymphocytes, significantly affects immune regulation and is implicated in the pathophysiology of these diseases. …”
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Evaluating Avacopan in the Treatment of ANCA-Associated Vasculitis: Design, Development and Positioning of Therapy by van Leeuwen JR, Quartuccio L, Draibe JB, Gunnarson I, Sprangers B, Teng YKO

“…Avacopan is an inhibitor of the C5a-receptor, which plays an important role in chemotaxis and the amplification loop of inflammation in AAV. In the most recent, international guidelines avacopan is recommended as steroid-sparing agents for the management of AAV. …”
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Significance of Preoperative Systemic Immune Score for Stage I Gastric Cancer Patients by Jun Lu, Long-long Cao, Ping Li, Jian-wei Xie, Jia-bin Wang, Jian-xian Lin, Qi-yue Chen, Mi Lin, Ru-hong Tu, Chang-ming Huang, Chao-hui Zheng

“…Univariate and multivariate survival analyses were conducted. Systemic inflammation factors were used to develop a scoring system for predicting AC benefits. …”
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Loss of protein C vs protein S results in discrepant thrombotic phenotypes by Chia-Jui Ku, Xinge Yu, Queena Y. Zhao, Steven J. Grzegorski, Jeffrey G. Daniel, Allison C. Ferguson, Jordan A. Shavit

“…Aside from coagulation, PC has been shown to have PS-independent roles in inflammation. proc mutants displayed altered inflammatory markers and defects in neutrophil migration independent of pros1. …”
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Reperfusion injury or cytokine storm? Utilizing plasmapheresis in severe trauma-induced multiorgan failure: a case report by Gun Woo Kim, Suyeong Hwang, Kyoung Hoon Lim, Sung Hoon Cho

“…Both reperfusion injury and cytokine storm can cause systemic inflammation and multiorgan failure. These two conditions may exhibit similar clinical features, necessitating supportive care primarily to prevent organ dysfunction. …”
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Use of D-Squame^® as a Minimally Invasive Technique to Evaluate Skin Immune Response Biomarkers in Canine Atopic Dermatitis by Marion Mosca, Nadège Milhau, Mélanie Legain, Adrien Idée, Xavier Langon, Didier Pin

“…Evaluation of skin inflammation biomarkers in canine atopic dermatitis (AD) currently requires skin biopsies. …”
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Polyphenol components in black chokeberry (Aronia melanocarpa) as clinically proven diseases control factors—an overview by Ningxuan Gao, Chi Shu, Yuehua Wang, Jinlong Tian, Yuxi Lang, Chenyu Jin, Xingyue Cui, Hanqian Jiang, Shi’an Liu, Zhiying Li, Wei Chen, Hao Xu, Bin Li

“…These studies showed that black chokeberry have good prevention and adjuvant therapy effects on hyperlipidemia,hypertension, diabetes and inflammation. Because there are different functional components in black chokeberry, its prevention and treatment of the same disease can come from multiple pathways, which provides a more reliable effectiveness for the disease control of different populations.…”
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Inhibition of Endoplasmic Reticulum Stress by 4-Phenyl Butyric Acid Presents Therapeutic Effects on Periodontitis: Experimental Studies In Vitro and in Rats by Yang Feng, Rong Zhang, Yi-rong Wang, Fei Chen, Qiang Luo, Chuan Cai, Yang Jiao, Peng Xue

“…The results showed that periodontitis-related inflammation gave rise to the upregulated expression levels of ER stress representative genes including GRP78, PERK, ATF4, and CHOP. …”
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MicroRNAs obtained from cervical swabs in predicting preterm birth by Rosalia Purbandari, Suheni Ninik Hariyati

“…Based on enrichment analysis, various miRNAs were found to be involved in several biomolecular signaling pathways leading to preterm birth, such as inflammation, chemokine and cytokine signaling pathway, and toll-like receptor signaling. …”
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Efficacy of transbronchial biopsy and frequency of pneumothorax in lung transplant recipients: single center experience by Ertan Sarıbaş, Ayse Nigar Halis, Sevinç Çıtak, Gonca Gecmen, Ahmet Murat Kazan, Musatafa Vayvada, Murat Ersin Cardak, Ahmet Erdal Taşçı

“…The proficiency of TBB pathology was found to be 90.7% (n = 263) for acute rejection (AR), 46.5% (n = 135) for airway inflammation, 50% (n = 145) for chronic lung allograft dysfunction (CLAD) with bronchiolitis obliterans (BO), and 89.6% (n = 260) for chronic vascular rejection. …”
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Probiotic biofilm modified scaffolds for facilitating osteomyelitis treatment through sustained release of bacteriophage and regulated macrophage polarization by Junwei Su, Yifan Wu, Zheng Wang, Dong Zhang, Xianquan Yang, Yong Zhao, Aixi Yu

“…In a rat model of infectious cranial defects, the scaffold not only effectively eliminated S. aureus and alleviated associated inflammation but also mediated macrophage-mediated immunoregulation, thus resulting in effective osteogenesis. …”
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Mesenchymal Stem Cells Enhance Pulmonary Antimicrobial Immunity and Prevent Following Bacterial Infection by Wenchao Li, Weiwei Chen, Saisai Huang, Xiaojun Tang, Genhong Yao, Lingyun Sun

“…However, MSC-treated mice exhibited accelerated bacterial clearance and moderate inflammation and tissue damage. Conclusion. Our study reported that unlike traditional immunosuppressants, modulation of MSCs on the recipient’s immune response is more elegant. …”
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Relative expression of IL-10 and TNF-α mRNA of kidney and spleen tissues of rat with and without mammary tumor after exposed to alternating current electric field by Nafisa Khoirun Widiasri, Anysah Nur Fauziyah, Firman Alamsyah, Rarastoeti Pratiwi

“…In the kidney and spleen, IL-10 and TNF-α play roles in the response to inflammation. Objective: This research aimed to evaluate the safety of electric field exposure to vital organs, by assessing the expression of IL-10 and TNF-α mRNA in the kidney and spleen of rats, both with and without breast tumors. …”
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Degradation of black tea theaflavin through C-ring cleavage by gut microbiota by Shuwei Zhang, Christina Ohland, Christian Jobin, Shengmin Sang

“…Theaflavin (TF) is one of the major color compounds in black tea and has demonstrated anti-inflammation, antioxidant, and anticancer effects properties. …”
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The Development of Methods of BLOTCHIP^®-MS for Peptidome: Small Samples in Tuberous Sclerosis by Kunio Yui, George Imataka, Kotaro Yuge, Hitomi Sasaki, Tadashi Shiohama, Kyoichi Asada, Hidehisa Tachiki

“…Our study on peptide analysis in Protosera Inc (Osaka, Japan) revealed that three peptides that were related to inflammation in two patients with tuberous sclerosis, who showed a 30% decrease in ASD symptoms following everolimus treatment. …”
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TMEM101 expression and its impact on immune cell infiltration and prognosis in hepatocellular carcinoma by Lingyun Kuang, Yilin Pang, Quangang Fang

“…Abstract Hepatocellular carcinoma (HCC) is a cancer caused by inflammation, which affects the immune response and treatment outcomes. …”
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