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6761
Role of Erythromycin-Regulated Histone Deacetylase-2 in Benign Tracheal Stenosis
Published 2020-01-01“…Erythromycin inhibited inflammation and excessive proliferation of granulation tissue after tracheobronchial mucosal injury by up-regulating the expression of HDAC2, it promoted wound healing and alleviated tracheobronchial stenosis. …”
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6762
Review on dietary supplements as an effective improvement of Alzheimer’s disease: focus on structures and mechanisms
Published 2024-07-01“…Especially with the widespread use of DSs, DSs containing polyphenols, alkaloids, terpenes, polysaccharides and other bioactive components can prevent AD by reducing Aβ deposition, inhibiting tau protein hyperphosphorylation, reconstructing synaptic dysfunction, weakening cholinesterase activity, regulating mitochondrial oxidative stress, neuronal inflammation and apoptosis. This review summarizes the anti-AD effects of the main DSs and their bioactive constituents, as well as the potential molecular mechanisms covers from 2017 to 2023. …”
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6763
Investigating the mechanistic role of oxidative stress in brain–gut axis disruption in rat model
Published 2024-11-01“…These findings suggest that endotoxin disrupts the gut’s antioxidant system and triggers inflammation, which could potentially lead to gut dysfunction. …”
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6764
Cataract Surgery with or without Intraocular Lens Implantation in Pediatric Uveitis: A Systematic Review with Meta-Analyses
Published 2021-01-01“…Outcome measures were preoperative and postoperative best-corrected visual acuity (BCVA), inflammation control, and rates of postoperative complications. …”
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6765
Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue
Published 2022-12-01“…At the same time, the C-Reactive Proteins are used to see the presence of inflammation due to infections such as Dengue Virus infection. …”
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6766
THE BENEFICIAL EFFECTS OF OLIVE TREE (OLEA EUROPAEA L.) IN THE NUTRITIONAL, PHARMACEUTICAL AND INDUSTRIAL APPLICATION: A REVIEW
Published 2024-12-01“…The potential of O. europaea plant extract showed antidiabetic, anticancer, asthma, cholesterol, uric acid, diarrhea, inflammation, blood pressure, antiheart and antiarthritis treatment. …”
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6767
Effects of interleukin-12/23 inhibitors and interleukin-17 inhibitors on myocardial functions in patients with severe psoriasis
Published 2024-12-01“…Background and Design: Systemic inflammation, which is involved in the pathogenesis of psoriasis, has been associated with the development of systemic diseases such as metabolic syndrome and cardiovascular disease. …”
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6768
The exercise-induced inflammatory response in inflammatory bowel disease: A systematic review and meta-analysis.
Published 2022-01-01“…<h4>Conclusion</h4>Heterogeneity among the identified literature may have led to exercise interventions being ineffective in reducing inflammation. Although the limited number of eligible studies may reduce the reliability of results, it emphasises the need for additional research in this domain. …”
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6769
A Novel Immune-Related Three-Gene Signature and Immune Infiltration Insights in Psoriasis and Chronic Kidney Disease
Published 2025-01-01“…Through further functional analysis, these genes were found to be primarily involved in the activation of inflammation and innate immune responses. Subsequently, six hub genes were determined using five topological algorithms. …”
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6770
A New Hope for the Patients of Non‐Alcoholic Steatohepatitis: FDA Gives Green Signal for Resmetirom Use
Published 2025-01-01“…ABSTRACT Background and Aims Non‐Alcoholic Steatohepatitis (NASH), a severe form of Non‐Alcoholic Fatty Liver Disease (NAFLD), is characterized by inflammation and fibrosis in the liver, often progressing to cirrhosis and hepatocellular carcinoma. …”
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6771
Effect of opercular deformity on morphological and transcriptomic profiling of gills in golden pompano (Trachinotus ovatus)
Published 2025-03-01“…KEGG pathway enrichment analysis of the DEGs indicated notable enrichment in pathways related to immune response and inflammation, including Staphylococcus aureus infection, leukocyte transendothelial migration, tight junction, and cell adhesion molecules pathways. …”
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6772
Computer modeling of the peculiarities in the interaction of IL-1 with its receptors in schizophrenia
Published 2024-05-01“…One of the primary theories regarding the development of schizophrenia revolves around genetics, indicating the involvement of hereditary factors in various processes, including inflammation. Research has demonstrated that inflammatory reactions occurring in microglia can impact the progression of the disease. …”
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6773
Toxicity and antioxidant assessment of ethanol leaf extract of Hibiscus surattensis in Wistar rats: hepatotoxicity evaluation
Published 2025-02-01“… Hibiscus surattensis is a medicinal plant with a vast beneficial use in the management and cure of a variety of diseases, ranging from urethritis to inflammation and vertigo among others. Notwithstanding the population's increasing use of it, particularly in rural regions, there is still lack of adequate investigation into its toxicity profile. …”
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6774
Genistein Implications in Radiotherapy: Kill Two Birds with One Stone
Published 2025-01-01“…Genistein protects normal cells by its potent antioxidant effect that reduces oxidative stress and mitigates radiation-induced apoptosis and inflammation. Conversely, genistein increases the radiosensitivity of tumor cells through specific mechanisms such as the inhibition of DNA repair, the arrest of the cell cycle in the G<sub>2</sub>/M phase, the generation of reactive oxygen species (ROS), and the modulation of apoptosis. …”
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6775
Association between dietary inflammatory index and osteoporosis in the US population: evidence from NHANES 2003–2010
Published 2025-01-01“…LASSO regression identified key dietary factors, which were used to build a nomogram with an AUC of 83.6%, indicating strong predictive accuracy.ConclusionA higher DII is strongly linked to increased osteoporosis risk, underscoring the importance of reducing dietary inflammation to help prevent osteoporosis.…”
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6776
Deciphering the significance of neutrophil to lymphocyte and monocyte to lymphocyte ratios in tuberculosis: A case-control study from southern India [version 2; peer review: 2 appr...
Published 2025-01-01“…Neutrophils, monocytes, and lymphocytes are crucial in the pathogenesis of granulomatous inflammation and immune reactions. We investigated the usefulness of the haematological parameters and their ratios, like the Neutrophil to Lymphocyte ratio (NLR) and Monocyte to Lymphocyte ratio (MLR), for diagnosing tuberculosis. …”
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6777
Genetics of Inflammatory Bowel Disease: Current Understanding and Future Directions
Published 2024-12-01“…These genetic variants, integral to IBD's etiology of IBD, have functional significance because they perturb immune regulation, compromise epithelial barrier integrity, and disrupt mucosal homeostasis, collectively contributing to intestinal inflammation through diverse mechanisms. Early detection of IBD is paramount for arresting disease progression and underscoring the importance of prognostic testing and genetic screening, especially in cases with familial predispositions or very early onset IBD. …”
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6778
Hijacking of the nervous system in cancer: mechanism and therapeutic targets
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6779
Therapeutic potential of targeting the IRF2/POSTN/Notch1 axis in nucleus pulposus cells for intervertebral disc degeneration
Published 2025-01-01“…Abstract Background Intervertebral disc degeneration (IDD) is a leading cause of low back pain, often linked to inflammation and pyroptosis in nucleus pulposus (NP) cells. …”
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6780
Queimadas e saúde da criança: rumo a um país inabitável?
Published 2024-12-01“…Among the pollutants produced by the fires, the fine inhalable particulate matter stands out, as it penetrates deeply into the lungs, causing inflammation and increasing the incidence of respiratory diseases, such as asthma exacerbations, bronchitis, and other chronic respiratory conditions. …”
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