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6661
Bifidobacterium breve BB05 alleviates depressive symptoms in mice via the AKT/mTOR pathway
Published 2025-01-01“…BB05 treatment also reduced pathological ileal damage, alleviated inflammation, and lowered serum levels of pro-inflammatory cytokines IL-6 and TNF-α. …”
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6662
Long-term outcomes of corneal transplantation: a review of 8,378 patients
Published 2025-01-01“…., glaucoma surgeries, IOL implantation) significantly increase re-transplantation risk, likely due to additional ocular stress and inflammation. Conclusion The study highlights the importance of patient age, surgeon experience, and the choice of surgical technique in the success rates of corneal transplants. …”
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6663
Pathogenic and therapeutic role of bile acids at reflux-gastritis
Published 2015-03-01“…Reflux-gastritis is chemical type gastritis, morphologically manifested by foveolar hyperplasia, edema, proliferation of smooth-muscle fibres of lamina propria, insignificant chronic inflammation. There is evidences of relation of intestinal metaplasia to duodenogastric reflux (DGR). …”
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6664
Evaluating the effect of virgin coconut oil pulling on viral load, bacterial load and inflammatory mediator levels in chronic periodontitis – A clinical study
Published 2025-01-01“…Background and objective: Periodontitis and dental caries are among the most prevalent oral diseases, with chronic periodontitis being a multifactorial, infectious condition that leads to inflammation in the supporting structures of the teeth, progressive attachment loss, and bone resorption. …”
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6665
The Impact of Surgical Trauma, BMI and Analgesics Intake on Postoperative Pain after Periapical Surgery in the Anterior Maxillary Region
Published 2024-01-01“…Study design: The study included 30 healthy, non-smoker adults of both genders, with an indication for periapical surgery on a single tooth in the upper anterior region, no history of prior surgery, no allergies to lidocaine with adrenaline or ibuprofen, no acute inflammation or pain, and a PAI of 3, 4, or 5. A single surgical team treated all patients by following the same surgical protocol. …”
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6666
Expression of Duodenal Iron Transporter Proteins in Diabetic Patients with and without Iron Deficiency Anemia
Published 2018-01-01“…In patients with T2DM and IDA, duodenal iron transport protein expression might be dependent on body iron stores rather than by chronic inflammation or diabetes per se.…”
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6667
Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice
Published 2016-01-01“…Obesity and metabolic syndrome and associated adiposity are a systemic condition characterized by increased mitochondrial dysfunction, inflammation, and inhibition of antioxidant genes, HO-1, and EETs levels. …”
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6668
Negative Pressure Smart Patch to Sense and Heal the Wound
Published 2025-01-01“…Compared with NPWT, NPSP projects a promising approach to removing bacteria, reducing local inflammation, and accelerating healing in a short period of time.…”
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6669
Atomized Neutrophil Membrane-coated MOF Nanoparticles for Direct Delivery of Dexamethasone for Severe Pneumonia
Published 2025-01-01“…In a mouse model of lipopolysaccharide (LPS)-induced pneumonia, UiO66-Dex@NMP significantly reduced lung inflammation compared to both the control model and Dex administered via inhalation. …”
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6670
Dysregulated tryptophan metabolism contributes to metabolic syndrome in Chinese community-dwelling older adults
Published 2025-01-01“…Dysregulation of tryptophan (TRP) metabolism, particularly alterations in the kynurenine (KYN) and serotonin pathways, has been linked to the onset of chronic inflammation, oxidative stress, and insulin resistance, key contributors to the development of MetS. …”
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6671
Systemic Candida parapsilosis Infection Model in Immunosuppressed ICR Mice and Assessing the Antifungal Efficiency of Fluconazole
Published 2015-01-01“…Postmortem and histopathological examinations presented fugal-specific lesions in multiorgans, especially in kidneys, characterized by inflammation, numerous microabscesses, and fungal infiltration. …”
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6672
Dupilumab for treatment of primary cutaneous amyloidosis in adults: two case reports and literature review
Published 2025-02-01“…Dupilumab, a human monoclonal antibody targeting for interleukin (IL)-4/13 receptor α chain, is widely applied in type 2 inflammation diseases treatment. This article reported two cases of refractory LA successfully treated with dupilumab and reviewed publications reporting dupilumab treatment for PCA.…”
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6673
The gut microbiota‐derived metabolite indole‐3‐propionic acid enhances leptin sensitivity by targeting STAT3 against diet‐induced obesity
Published 2024-12-01“…IPA or Clostridium sporogenes supplement effectively controls weight gain, improves glucose metabolism, and reduces inflammation in DIO mice. IPA fails to achieve such effects in ob/ob mice, while exogenous leptin administration restores the therapeutic effect of IPA. …”
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6674
Fecal Microbiota Transplantation from Methionine-Restricted Diet Mouse Donors Improves Alzheimer’s Learning and Memory Abilities Through Short-Chain Fatty Acids
Published 2025-01-01“…The results showed that MR reversed the reduction in SCFAs induced by AD, and further activated the free fatty acid receptors, FFAR2 and FFAR3, as well as the transport protein MCT1, thereby signaling to the brain to mitigate inflammation and enhance the learning and memory capabilities. …”
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6675
Gut microbiome in non-alcoholic fatty liver disease
Published 2025-01-01“…The release of lipopolysaccharides (LPS) from intestines to portal vein which are transported to the liver, may trigger hepatic inflammation, steatosis and even fibrosis. Moreover, the gut microbiome induces the conversion of primary bile acids (BAs) to secondary BAs, which activates intestinal receptors, such as FXR and TGR5. …”
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6676
Genomic Introgression Between Critically Endangered and Stable Species of Darwin's Tree Finches on the Galapagos Islands
Published 2025-01-01“…Alleles were annotated to genes associated with inflammation, immunity, brain function and development. …”
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6677
Binucleated Neuron as a Potential Histologic Marker of Neuroregeneration in Rat Sciatic Nerve Injury Model
Published 2024-12-01“…It is known that binucleated neurons (BNs) are present in normal rat populations, increase following the transplantation of bone marrow-derived cells into the cerebellum, and disappear with inflammation. We propose a new potential histologic marker as a probable alternative to conventional axonal histomorphometric analysis for DRG in the Sprague Dawley rat sciatic nerve injury model. …”
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6678
Role of Janus Kinase inhibitors in the management of pulmonary involvement due to Long COVID-19 disease: A case control study
Published 2023-07-01“…CONCLUSION: JAKi can be used as immunomodulatory drugs in hypoxic OSC cases having evidence of ongoing inflammation.…”
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6679
Incidence and prognosis associated with troponin elevation after cardiac surgery: a prospective cohort study
Published 2022-08-01“…However, numerous confounding elements, such as inflammation, liver and renal function biomarkers, have been associated with troponin variations. …”
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6680
Inflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles
Published 2025-01-01“…Our findings illuminate the personalized nature of corona formation under a dynamic inflammatory condition and its impact on NP-mediated immune activation profiles and inflammation, suggesting that disease progression-related alterations in plasma composition can manifest in the corona to cause unintended toxicity and altered therapeutic efficacy.…”
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