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6641
Effect of prednisolone acetate eye drops on blood glucose profile in Indian population
Published 2025-01-01“…Background: One of the common indications of topical steroids is to control postoperative inflammation. This study aims to evaluate changes in blood glucose concentrations in diabetic and nondiabetic patients treated with a postoperative regimen of 1% topical prednisolone acetate after cataract surgery. …”
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6642
Murine Type III interferons are functionally redundant and correlate with bacterial burden during influenza/bacterial super-infection.
Published 2021-01-01“…Further, the IFNλ response to influenza, as opposed to changes in cellular inflammation or viral load, significantly correlates with susceptibility to bacterial super-infection. …”
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6643
Tumor microbiome: roles in tumor initiation, progression, and therapy
Published 2025-02-01“…Moreover, we outline the general mechanisms by which specific microbes induce tumor initiation, including the activation of carcinogenic pathways, deoxyribonucleic acid (DNA) damage, epigenetic modifications, and chronic inflammation. We further propose the tumor microbiome may evade immunity and promote angiogenesis to support tumor progression, while uncovering specific microbial influences on each step of the metastatic cascade, such as invasion, circulation, and seeding in secondary sites. …”
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6644
Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases
Published 2017-01-01“…ROCK is involved in angiogenesis and hyperpermeability and also in the pathogenesis of various pathologies such as inflammation and fibrosis. It has been expected that ROCK inhibitors will become new molecular target drugs for vitreoretinal diseases. …”
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6645
Protection of Corneal Limbus from Riboflavin Prevents Epithelial Stem Cell Loss after Collagen Cross-Linking
Published 2018-01-01“…Protection of limbus from riboflavin during CXL was effective in preserving LESCs. However, inflammation was increased in the cornea treated with riboflavin using a ring.…”
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6646
Genetics of aging and longevity
Published 2016-09-01“…These trends include heterochromatin recovery, retrotransposition suppression, aneuploidy elimination; restoring the acidity of lysosomes; telomere elongation; suppression of chronic inflammation; elimination of protein cross-links; elimination of senescent cells; recovery of NAD+ levels; inhibition of mTOR, S6K, TGF-β, AT1; controlled activation of the ”longevity program” genes FOXO, AMPK, PGC1α, NRF2.…”
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6647
Penetration of linezolid and tedizolid in cerebrospinal fluid of mouse and impact of blood–brain barrier disruption
Published 2025-01-01“…This penetration is hindered by different barriers, including the blood–brain barrier, which is the most impermeable. However, inflammation may lead to structural alterations of these barriers, modifying their permeability. …”
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6648
Sonographic assessment of hand and wrist tendons abnormalities
Published 2024-12-01“…Abstract Background Tendons of the hand and wrist are the seat of different types of pathologies that might be attributed to degenerative changes, inflammation, or even rupture. All of which can significantly impair hand functions and hence, the quality of life. …”
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6649
Multidimensional library for the improved identification of per- and polyfluoroalkyl substances (PFAS)
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6650
An atypical presentation of autoimmune hepatitis with delayed menarche in a Nigerian adolescent: a case report
Published 2025-01-01“…Abstract Background Autoimmune hepatitis is a chronic liver disease marked by immune-mediated inflammation, necrosis, and the potential to progress to cirrhosis if not treated. …”
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6651
Clinical and Epidemiological Study on Tubercular Uveitis in a Tertiary Eye Care Centre in Italy
Published 2020-01-01“…Conclusion. Intraocular inflammation can be the first manifestation of tuberculosis. …”
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6652
Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice
Published 2020-01-01“…Aberrant key enzyme activities in glucometabolic pathways, AR, PK, and PDK/PDH, were also restored; indexes of oxidative stress and inflammation, NAD+/NADH ratio, and AGEs in the kidneys were mostly significantly preserved after pyruvate treatments. …”
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6653
Axial Spondyloarthritis in Black Americans: An Observational Study From Five Centers in Shelby County, Tennessee
Published 2025-01-01“…The study identified that Black Americans have more odds of having advanced sacroiliitis on x‐rays, more hip involvement, and higher markers of inflammation. It also showed that, regardless of race or ethnicity, there is a significant diagnostic delay.…”
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6654
Protective effects of small RNAs encapsulated in Artemisia Capillaris-derived exosomes against non-alcoholic fatty liver disease
Published 2025-01-01“…Additionally, the expression levels of proteins and RNAs associated with lipogenesis and inflammation were analyzed.ResultsThe NAFLD mouse model exhibited notable liver damage, including lipid deposition and inflammatory responses. …”
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6655
The Effects of Pitavastatin on Nuclear Factor-Kappa B and ICAM-1 in Human Saphenous Vein Graft Endothelial Culture
Published 2019-01-01“…Low-dose (0.1 μM/L) and high-dose (1μM/L) pitavastatin calcium were administered as a frontline therapy in human saphenous endothelial cell culture, followed by induction of inflammation by TNF-α and determination of mRNA level alterations of ICAM-1 and NF-κB genes of endothelial cells using the qRT-PCR method. …”
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6656
miR-197 Participates in Lipopolysaccharide-Induced Cardiomyocyte Injury by Modulating SIRT1
Published 2022-01-01“…Sepsis is a systemic inflammation and is capable of inducing myocarditis, which is a major leading cause of death in patients. …”
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6657
The Role of Controlled Breathing in Pain Management
Published 2025-02-01“…This review examines the mechanisms underlying these effects, highlighting the role of the vagus nerve in regulating relaxation and reducing inflammation. Empirical studies demonstrate that DSB positively influences chronic pain conditions, including menstrual pain and visceral pain, by modulating pain perception and emotional regulation. …”
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6658
Age distribution and types of breast lesions among Afghan women diagnosed by fine needle aspiration cytology (FNAC) at a tertiary care centre in Afghanistan: a descriptive cross-se...
Published 2020-09-01“…Inflammatory conditions were diagnosed in 9.7% of cases, granulomatous inflammation in 9.1%, lesions only suspicious for malignancy in 5.5%, lipoma in 2.8% and miscellaneous benign lesions in 11.1%. …”
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6659
SALIVARY FUNCTION AND BIOMARKER PROFILES IN RELATION TO ORAL HEALTH IN PATIENTS WITH PRE-DIALYSIS CHRONIC KIDNEY DISEASE
Published 2024-12-01“…Dental health was poor, reflected by a high DMFT score, fair oral hygiene, and moderate to severe gingival inflammation in 43.1% (n=22). Moderate or severe periodontal disease was observed in 45.1% (19.6% moderate, 25.5% severe), while median CAL and PD indicated moderate periodontal health. …”
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6660
Activation of the Peroxisome Proliferator-Activated Receptors (PPAR-α/γ) and the Fatty Acid Metabolizing Enzyme Protein CPT1A by Camel Milk Treatment Counteracts the High-Fat Diet-...
Published 2021-01-01“…CM dampened the steatosis, inflammation, and ballooning degeneration of the hepatocytes. …”
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