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6481
In Vivo Antiplasmodial Activity and Toxicological Analyses of the Ethanolic Leaf and Twig Extract of Faurea speciosa Welw. (Proteaceae)
Published 2021-01-01“…A 55.50% reduction of edema in the anti-inflammatory test indicated moderate success in reducing inflammation. The total antioxidant capacity of the extract was determined to be 65.4 mg AAE/g of extract, while in the DPPH radical scavenging assay, the IC50 value was found to be 499.4 μg/mL. …”
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6482
Maternal Circulating Concentrations of Tumor Necrosis Factor-Alpha, Leptin, and Adiponectin in Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis
Published 2014-01-01“…Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications. Inflammation may play a role in the pathogenesis of GDM. …”
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6483
The injectable hydrogel loading cannabidiol to regulate macrophage polarization in vitro for the treatment of chronic enteritis
Published 2024-10-01“…Conclusion: The vitro experiments have confirmed that the CBD-loaded hydrogel system has good biosafety, and can alleviate inflammation by regulating the polarization direction of macrophages, and then inhibiting the secretion of pro-inflammatory factors, laying a strong foundation for the treatment of chronic enteritis.…”
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6484
Coinfection of Hepatitis B and C Viruses and Risk of Hepatocellular Carcinoma: Systematic Review and Meta-analysis
Published 2024-12-01“…Introduction: Hepatitis B and C are viral infections causing chronic liver inflammation and, when left untreated, lead to cirrhosis and a risk for hepatocellular carcinoma, the most common type of primary liver cancer with high mortality. …”
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6485
Effect of Hesperidin as an Adjunct to Scaling and Root Planing on Clinical Parameters and Serum C-Reactive Protein Level in Chronic Periodontitis: A Randomized, Triple-Blind, Place...
Published 2024-12-01“…Serum C-reactive protein (CRP) levels were measured at baseline and 3 weeks to assess systemic inflammation. Results: Of the 84 patients, 80 completed the study, with 60 males and 20 females. …”
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6486
DPPH Scavenging Activity, Reducing Power, and Metal Chelating Capacity of Compound 1-(2,5-dihydroxyphenyl)-3-pyridine-2-yl-propenone
Published 2023-12-01“…The excessive free radicals in the body could stimulate oxidative stress which has been implicated in several diseases such as cancer, inflammation, aging, and cardiovascular diseases. The presence of antioxidants can diminish the reactivity of free radicals. …”
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6487
Zone V Extensor Tendon Repair with a Palmaris Longus Tendon Autograft and Human Umbilical Membrane
Published 2020-01-01“…., Alachua, FL) to separate adjacent tissue and reduce inflammation. Even without access to formal physical therapy, our patient had excellent functional outcomes at his final follow-up visit. …”
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6488
A single-cell 3D dynamic volume control system for chondrocytes
Published 2024-10-01“…In articular cartilage, zone-specific cellular morphology is a typical characteristic of cartilage tissue, which is related with chondrocyte function, inflammation and osteoarthritis (OA). Chondrocyte hypertrophic phenotype is a criticle physiological process which indicates a hallmark of chondrocyte terminal differentiation and bone formation. …”
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6489
Protective effects of Euphorbia heterophylla against testicular degeneration in streptozotocin-induced diabetic rats in relation to phytochemical profile.
Published 2025-01-01“…The protective effect of EH-EtOH against testicular degeneration in the rat model of DM was evaluated by measuring improvements in blood glucose levels, body weight, testicular inflammation, oxidative damage, testicular microcirculation impairment, and apoptosis of testicular cells induced by STZ. …”
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6490
Effectiveness of mahkota dewa leaves extract as a biofilm inhibitor of propionibacterium acnes growth
Published 2023-06-01“…Acne vulgaris is a chronic inflammation of the pilosebaceous unit with various clinical manifestations caused by bacterial colonization of Propionibacterium acnes. …”
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6491
Gut Microbiota Secondary Metabolites: Key Roles in GI Tract Cancers and Infectious Diseases
Published 2025-01-01“…In gastrointestinal (GI) cancers such as colorectal, liver, and gastric cancer, microbial metabolites can drive tumorigenesis by promoting inflammation, DNA damage, and immune evasion. Conversely, these same metabolites hold therapeutic promise, potentially enhancing responses to chemotherapy and immunotherapy and even directly suppressing tumor growth. …”
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6492
Possible Potentiation by Certain Antioxidants of the Anti-Inflammatory Effects of Diclofenac in Rats
Published 2014-01-01“…Rats were treated daily with antioxidants, that is, a-lipoic acid (50 mg/kg), selenium (2.5 mg/kg), vitamin C (1 g/kg), vitamin E (300 mg/kg), or zinc (25 mg/kg) on seven successive days and then received a single treatment with diclofenac or saline before carrageenan was injected to induce paw inflammation. The results indicated that these combinations did not significantly affect the percentage inhibition of paw edema caused by diclofenac alone; however, some combination treatments ameliorated signs of concomitant oxidative stress (such as alterations in plasma malondialdehyde (MDA) levels, hemolysate reduced glutathione levels, and erythrocytic superoxide dismutase enzyme activities) imparted by diclofenac alone. …”
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6493
Case Report: Potential benefits of a single functional neurology intervention in athletic rehabilitation and recovery: a case study
Published 2025-01-01“…We found how a single session of functional neurology improved load tolerance, enabling her to lift weights at pre-injury levels after just a single session of functional neurology and reduced pain perception from 80 to 0 and fatigue perception from 90 to 20 on a 100-point scale while thermographic data showed up to a 15% decrease in body temperature indicating reduced inflammation and improved muscle recovery. Then, we found how a single functional neurology intervention produced an improve in sports performance, pain and fatigue perceptions, and peripheral vascular response in an inter-national female weightlifting athlete with an initial incapacity to tolerate weight. …”
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6494
Effect of Alkaloids from Nelumbinis Plumula against Insulin Resistance of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Mice
Published 2016-01-01“…The present results supported the view that the pathogenesis of NAFLD was complex with inflammation, together with increasing serum glucose and IR. …”
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6495
The predictive effects of adiponectin and irisin hormones on diagnosis and clinical involvement of Sarcoidosis
Published 2024-12-01“…Adipokines and myokines secreted from adipose and muscle tissue play a role in the pathogenesis or protection against many inflammatory and autoimmune diseases in which inflammation and immunity form the basis. In our study, we aimed to investigate the role of the irisin and adiponectin in sarcoidosis. …”
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6496
Neuroinflammation and Oxidative Stress in Diabetic Neuropathy: Futuristic Strategies Based on These Targets
Published 2014-01-01“…The cross talk between oxidative stress and inflammation is due to the activation of NF-κB and AP-1 and inhibition of Nrf2, peroxynitrite mediate endothelial dysfunction, altered NO levels, and macrophage migration. …”
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6497
Multiple Roles of SIRT2 in Regulating Physiological and Pathological Signal Transduction
Published 2022-01-01“…Therefore, SIRT2 can be involved in metabolic disorder-related inflammation and oxidative stress, thereby triggering the occurrence of metabolic disorder-related diseases, such as neurodegenerative diseases, tumours, diabetes, and cardiovascular diseases. …”
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6498
Diet-Induced Adipocyte Browning
Published 2021-11-01“…In addition, it contributes to the lowering of adipose tissue and systemic inflammation, which are promoted in obese states. Thus, the role of adipocyte browning should be emphasized in the context of a dramatically increasing population of obese individuals. …”
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6499
Biologics in ocular inflammatory diseases – Experience from a tertiary referral eye care center in South India
Published 2025-02-01“…Conclusion: In this study, we have analyzed the results of biologics in different anatomic types of ocular inflammation and etiologies. The success rate of biologics was low in parsplanitis, idiopathic uveitis, and Blau-associated uveitis and higher in other etiologies.…”
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6500
Antioxidants from microalgae and their potential impact on human well-being
Published 2024-05-01“…Moreover, it delves into compelling in vitro and in vivo studies showcasing microalgae-derived antioxidants’ protective effects against oxidative damage, inflammation, cardiovascular diseases, and neurodegenerative disorders. …”
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