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6461
Culture and Use of Mesenchymal Stromal Cells in Phase I and II Clinical Trials
Published 2010-01-01“…Through the release of cytokines, growth factors and biologically active molecules, MSCs exert important paracrine effects during tissue repair and inflammation. Moreover, MSCs have immunosuppressive properties related to non-HLA restricted immunosuppressive capacities. …”
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6462
Diagnostic Value of the 13C Methacetin Breath Test in Various Stages of Chronic Liver Disease
Published 2011-01-01“…Forty-seven patients had liver cirrhosis (Child Pugh A = 11, Child Pugh B = 15, and Child Pugh C = 21), 21 had fibrosis, and 9 had chronic inflammation. The sensitivity and positive predictive value for liver fibrosis, cirrhosis (all stages), Child-Pugh A, Child-Pugh B, and Child-Pugh C were 65% and 56%, 89% and 89%, 67% and 42%, 40% and 40%, and 50% and 77%, respectively. …”
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6463
CORRELATIONS OF GIVING DESINFECTION (ALCOHOL SWAB) WHEN GIVING INTRAVEIN INJECTION WITH PHLEBITIS
Published 2020-05-01“…Introduction: Phlebitis is inflammation of the veins caused by chemical irritations of additives and drugs that are given intravenously. …”
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6464
Prevalence of Metabolic Syndrome in Patients with Psoriasis
Published 2012-01-01“…It is thought that chronic inflammation results in metabolic diseases and proinflammatory cytokines give rise to the development of atherogenesis, peripheral insulin resistance, hypertension, and type 2 diabetes. …”
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6465
Role of Probiotics in the Management of Patients with Ulcerative Colitis and Pouchitis
Published 2024-12-01“…While IPAA improves patient outcomes, it can be associated with pouchitis, a common and debilitating complication characterized by inflammation of the pouch. The development of pouchitis is closely linked to dysbiosis—an imbalance in the gut microbiota. …”
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6466
The role of glucagon-like peptide-1 receptor (GLP-1R) agonists in enhancing endothelial function: a potential avenue for improving heart failure with preserved ejection fraction (H...
Published 2025-02-01“…GLP-1R agonists, including semaglutide and liraglutide, have demonstrated significant cardioprotective effects, such as improving vascular endothelial function, reducing inflammation, and preventing atherosclerosis. Clinical trials, such as the STEP-HFpEF trial, have shown positive results in reducing symptoms and physical restrictions in HFpEF patients. …”
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6467
The Neutrophil to Lymphocyte Ratio and Other Full Blood Count Indices in Retinal Diseases: A Systematic Review of the Literature
Published 2025-01-01“…<i>Background and Objectives:</i> The neutrophil to lymphocyte ratio (NLR) and other full blood count indices have been used as a marker of inflammation in a variety of diseases. The aim of the current review is to summarize the existing knowledge on the use of these indices in retinal diseases. …”
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6468
In Vitro and In Vivo Wound Healing Activity of Astragalus floccosus Boiss. (Fabaceae)
Published 2022-01-01“…Histopathological results indicated that congestion, edema, inflammation, necrosis, and angiogenesis decreased during the examination and fibroblast proliferation fibrosis epithelization was increased especially in the RFF group in comparison to the silver sulfadiazine and free groups. …”
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6469
Relationship of Biochemical and Sonographic Markers with Disease Severity in Rosacea Patients Without Cardiovascular Disease
Published 2025-01-01“…Although the pathogenesis of both atherosclerosis and rosacea demonstrate notable similarities, particularly in the central role of inflammation, significant gaps in understanding these connections remain. …”
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6470
Effect of Antioxidants on the Gut Microbiome Profile and Brain Functions: A Review of Randomized Controlled Trial Studies
Published 2025-01-01“…Antioxidants, including vitamins C, B2, and D, along with polyphenols such as xanthohumol, fermented papaya, peanuts, and berry extracts, demonstrate the potential to support cognitive function and promote gut health through mechanisms that modulate microbiome diversity and reduce inflammation. However, observed changes in microbiome diversity were modest and inconsistent across the studies. …”
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6471
The Potential Role of Korean Mistletoe Extract as an Anti-Inflammatory Supplementation
Published 2021-01-01“…Interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and C-reactive protein (CRP) were used as markers for inflammation. After supplementation, IL-6 and TNF-α levels were significantly lowered in the KME group than in the CON group at baseline, immediately after exercise, and following 30 minutes of recovery. …”
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6472
Diet and medical foods in Parkinson’s disease
Published 2019-06-01“…Gut microbial dysbiosis and altered microbial metabolites found in PD may lead to chronic low-grade inflammation in gut and brain. Interventions targeting gut microbiota, such as the supplementation of probiotics, may provide novel approaches to PD in regard to both symptomatic treatment and disease modification. …”
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6473
The Role of Genetic and Immune Factors for the Pathogenesis of Primary Sclerosing Cholangitis in Childhood
Published 2016-01-01“…Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease characterized by chronic inflammation of the biliary tree resulting in liver fibrosis. …”
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6474
Haptoglobin Genotype and Risk Markers of Cardiovascular Disease in Patients with Chronic Kidney Disease
Published 2013-01-01“…Sudden cardiac death and atherosclerosis have a major impact on cardiovascular mortality in chronic kidney disease (CKD). Inflammation with elevated high-sensitive C-reactive protein (hs-CRP) is involved in both sudden cardiac death and atherosclerosis, and decreased heart rate variability (HRV) is a predictor of both sudden cardiac death and atherosclerosis. …”
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6475
Isolation, Culture, and Characterization of Primary Kidney Fibroblasts from Human Patients with Chronic Antibody-mediated Kidney Transplant Rejection
Published 2024-12-01“…Background: Inflammation and fibrosis are the primary occurrences of chronic antibody-mediated rejection (CABMR) in kidney transplant patients. …”
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6476
Endothelial STAT3 Modulates Protective Mechanisms in a Mouse Ischemia-Reperfusion Model of Acute Kidney Injury
Published 2017-01-01“…STAT3 is a transcriptional regulator that plays an important role in coordinating inflammation and immunity. In addition, there is a growing appreciation of the role STAT3 signaling plays in response to organ injury following diverse insults. …”
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6477
Etiology and epizootology of bovine mastitis (analytical review)
Published 2024-03-01“…The disease causes significant economic losses to dairy industry both in the Russian Federation and globally. Mastitis is an inflammation of the mammary gland that develops in response to the effects of various factors of the external and internal environment, which are classified as mechanical, physical, biological, etc. …”
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6478
Respiratory Epithelium Lined Cyst of the Maxilla: Differential Diagnosis
Published 2017-01-01“…It could also be an unusual radicular cyst in which the stratified squamous epithelium was destroyed by inflammation and replaced by a respiratory epithelium of the maxillary sinus.…”
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6479
Effect of Premna pubescens Ethanol Extract on Erythrocyte Count and Kidney Histology in Rattus norvegicus L
Published 2025-01-01“…Histological analysis of the kidneys revealed clearer glomeruli and tubules, with reduced signs of inflammation and bleeding compared to the SRBC-treated group. …”
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6480
Potential Role of Peptidylarginine Deiminase Enzymes and Protein Citrullination in Cancer Pathogenesis
Published 2012-01-01“…Here, we will discuss the potential role of PADs in tumor progression and tumor-associated inflammation. In the context of cancer, increasing clinical evidence suggests that PAD4 (and possibly PAD2) has important roles in tumor progression. …”
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