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6421
Pentraxin 3: a novel biomarker in pediatric central nervous system infections
Published 2025-01-01“…Pentraxin 3 (PTX3) is an acute-phase mediator that increases in body fluids and plasma throughout inflammation. Our study was designed to assess the diagnostic and prognostic value of cerebrospinal fluid (CSF) PTX3 levels in pediatric patients with different central nervous system (CNS) infections. …”
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6422
A Cross-Sectional Study to Evaluate the Prevalence and Severity of Gingivitis among High School Students in Erbil City-Iraq.
Published 2024-03-01“… Background and objective: There is an increase in the gingival inflammation without an associated increase in plaque level during puberty. …”
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6423
Gingivitis Effectiveness of Emulgel Containing 2% Resveratrol in Orthodontic Patients: An 8-Week Randomized Clinical Trial
Published 2021-01-01“…The Emulgel containing 2% resveratrol is effective in improving gingival health in orthodontic patients and can lower gingival inflammation over 8 weeks. This trial is registered with the Iranian registry of clinical trials (https://irct.ir/) IRCT20130812014333N91.…”
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6424
Research Status and Trends in Periodontal Ligament Stem Cells: A Bibliometric Analysis over the Past Two Decades
Published 2024-01-01“…Research topics mainly included mechanism of periodontal diseases, tissue engineering and regeneration, biological characteristics of PDLSCs, and comparison with other stem cells. Infectious inflammation and mechanical stimulation were important pathological conditions and research topics. …”
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6425
Current Insight of Peptide-Based Hydrogels for Chronic Wound Healing Applications: A Concise Review
Published 2025-01-01“…Typically, they do not progress through the usual phases of healing, which include hemostasis, inflammation, proliferation, and remodeling, within the expected timeframe. …”
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6426
Continuous Positive Linear Association between the Monocyte to High-Density Lipoprotein Cholesterol Ratio and Hypertension: A Cross-Sectional Study
Published 2022-01-01“…Hypertension poses a major threat to human health, and inflammation is associated with hypertension. The monocyte to high-density lipoprotein cholesterol ratio (MHR) represents a new inflammatory indicator. …”
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6427
Lipid-Induced Mechanisms of Metabolic Syndrome
Published 2020-01-01“…On the one hand, the lack of n-3 polyunsaturated fatty acids (PUFAs) in the body leads to impaired molecular mechanisms of glucose transport, the formation of unresolved inflammation. On the other hand, excessive formation of free fatty acids (FFAs) underlies the development of oxidative stress and mitochondrial dysfunction in MetS. …”
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6428
Neutrophil-to-lymphocyte ratio: association with microcirculatory changes detected by nailfold capillaroscopy in scleroderma patients and its relation to disease severity
Published 2025-01-01“…Conclusion High N/L ratio as a marker of inflammation was found to reflect severity of systemic sclerosis and is associated with larger capillary diameter and lower capillary number in nailfold capillaroscopy. …”
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6429
Unleashing the potential of extracellular vesicles for ulcerative colitis and Crohn's disease therapy
Published 2025-03-01“…Current therapies focus on reducing inflammation but often prove inadequate, leading to a substantial need for novel approaches. …”
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6430
Transcriptomics-based investigation of resistance differences to swine fever between large white pigs and min pigs
Published 2025-03-01“…Furthermore, genes involved in inflammation and antiviral responses, including IL16, IL27, USP18, and DHX58, were upregulated in post-vaccination Min pigs compared to post-vaccination Large White pigs. …”
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6431
Combining machine learning and single-cell sequencing to identify key immune genes in sepsis
Published 2025-01-01“…Gene Set Enrichment Analysis (GSEA) revealed that the key genes involved multiple immune response and inflammation-related signaling pathways. Subsequently, diagnostic models were constructed using four machine learning algorithms (Logistic regression, AdaBoost, KNN, and XGBoost) based on the identified key genes. …”
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6432
Effects of Endurance Training and Chlorogenic Acid on Oxidative and Nitrosative Stress Markers in Prediabetic Male Mice
Published 2025-01-01“…Background: Many studies have investigated the effects of exercise and chlorogenic acid in controlling and improving diabetes and reducing inflammation. This study aimed to investigate the effects of endurance exercise and chlorogenic acid on oxidative and nitrosative stress indicators in skeletal muscle tissue of male C57BL/6 mice. …”
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6433
In silico data mining of large-scale databases for the virtual screening of human interleukin-2 inhibitors
Published 2021-03-01“…Uncontrolled activated T cells play a key role in the pathophysiology by stimulating inflammation and autoimmune diseases like arthritis, psoriasis and Crohn’s disease. …”
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6434
Functional morphology of digestive organs of newborn calves and pathogenesis of escherichiosis
Published 2023-09-01“…Structural changes in digestive organs had an alterative nature at the initial disease stage, whereas in case of clinically pronounced disease signs there were manifestations of catarrhal-necrotic inflammation with multiple hemorrhages n the gastrointestinal tract and parenchymal organs. …”
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6435
Effectiveness of ethanol extract of Morinda citrifolia L. as an anti-inflammatory: A preclinical study
Published 2024-12-01“…Ethanol extract of noni fruit demonstrates significant anti-inflammatory effects, particularly at higher doses, but is less effective than triamcinolone in resolving tissue inflammation.…”
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6436
Mechanistic modelling of allergen-induced airways disease in early life
Published 2025-01-01“…In this study, we developed an in silico model describing the pulmonary immune response to a common allergen, house dust mite, to investigate its downstream impact on the pathophysiology of asthma, including airway eosinophilic inflammation, remodelling, and lung function. We hypothesised that altered epithelial function following allergen exposure determines the onset of airway remodelling and abnormal lung function, which are irreversible with current asthma therapies. …”
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6437
Dual-mode-driven nanomotors targeting inflammatory macrophages for the MRI and synergistic treatment of atherosclerosis
Published 2025-01-01“…The asymmetric deposition of Pt on Gd-MCNs catalyzed H2O2 at the inflammatory site to produce O2, which could promote the self-motion of the nanomotor and ease inflammation microenvironment of AS plaque. Near-infrared (NIR) laser irradiation promoted the photothermal conversion of Gd-MCNs to generate the thermal propulsion of nanomotor and photothermal ablation of inflammatory macrophages. …”
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6438
Analysis of selected factors influencing mortality of patients with COVID-19 treated in a community hospital in a rural region of Poland
Published 2025-02-01“…Conclusion: Fever and high laboratory values of inflammation, in particular coexisting sepsis, worsened the prognosis in patients with COVID-19. …”
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6439
Artificial intelligence in CT diagnosis: Current status and future prospects for ear diseases
Published 2024-12-01“…The advancements have made CT become the preferred method for diagnosing various ear conditions, including congenital malformations, trauma, inflammation, and neoplasm. Artificial intelligence (AI) has brought significant breakthroughs in the CT diagnosis. …”
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6440
Intestinal Schwannoma: A Clinicopathological, Immunohistochemical, and Prognostic Study of 9 Cases
Published 2019-01-01“…Two patients underwent endoscopic biopsy, and the pathological results revealed inflammation and necrosis. One patient had increased neuron-specific enolase (NSE) levels. …”
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