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6381
Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case
Published 2011-01-01“…The rarity of this affection, the need of a differential diagnosis with fat-containing tumors, and the possibility of parenchymal inflammation associated with RSL, potentially responsive to steroids, are also discussed.…”
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6382
Fluoride-induced testicular and ovarian toxicity: evidence from animal studies
Published 2025-01-01“…In both males and females, F exerts its adverse effects by triggering apoptosis, autophagy, inflammation, mitochondrial dysfunction, reduction in ATP synthesis, and modulation of important genes involved in steroidogenesis. …”
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6383
Higher serum Metrnl levels are associated with increased vascular calcification in hemodialysis patients
Published 2025-12-01“…Background Meteorin-like (Metrnl) is a newly identified secreted protein that plays important roles in metabolic and inflammation-related diseases. Our study aimed to evaluate serum Metrnl levels and establish their relationship with vascular calcification (VC) in hemodialysis (HD) patients.Methods In total, 313 HD patients and 41 healthy individuals, as controls, were included. …”
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6384
DPSCs Protect Architectural Integrity and Alleviate Intervertebral Disc Degeneration by Regulating Nucleus Pulposus Immune Status
Published 2022-01-01“…RNA sequencing and in vitro experiments demonstrated that DPSCs supernatant could downregulate NP cells’ inflammation-related NF-κB and JAK-STAT pathways, reduce IL-6 production, increase collagen II expression, and mitigate apoptosis. …”
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6385
Nanoparticles in Hormonal Regulation of the Female Reproductive System
Published 2025-01-01“…However, the accumulation of NPs in reproductive organs raises concerns about their potential toxicity, particularly in terms of oxidative stress, inflammation, and DNA damage. This review underscores the need for further research to fully understand the long-term effects of NPs on female reproductive health and to establish safe exposure limits. …”
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6386
Euodiae Fructus: a review of botany, application, processing, phytochemistry, quality control, pharmacology, and toxicology
Published 2025-01-01“…So far, more than 300 metabolites have been extracted and identified from EF, exhibiting various pharmacological effects, such as cardiovascular protection, gastrointestinal protection, neuroprotection, anti-inflammation, analgesia, anti-tumor, glucose and lipid metabolism regulation, etc. …”
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6387
Features of the nasal microbiota in patients with allergic rhinitis: A review
Published 2024-10-01“…The absence of microbiota can increase the response of the immune system and reduce the number of cells that contribute to the regulation of inflammation. This review presents an analysis of the composition of the normal microflora of otolaryngological organs and its effect on the occurrence of allergic rhinitis.…”
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6388
Etoricoxib–NLC Mitigates Radiation-Induced Ovarian Damage in Rats: Insights into Pro-Inflammatory Cytokines, Antioxidant Activity, and Hormonal Responses
Published 2024-12-01“…These therapeutic effects were achieved through the modulation of oxidative stress, inflammation, augmentation of antioxidant defenses (including <i>Nrf2</i> activation), support for cell survival pathways (via PI3K/Akt signaling), regulation of MAPK, mitigation of fibrosis (<i>TGF-β</i>), and preservation of ovarian reserve (as evidenced by AMH, FSH/LH, and estrogen levels). …”
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6389
Treatment of Extensive Plaque Psoriasis and Psoriatic Arthropathy using Methotrexate in a Patient with High Serum Alkaline Phosphatase
Published 2019-03-01“…Background: Psoriasis is an autoimmune inflammatory, chronic, and relapsing disease of the skin, which can also present with severe joint inflammation and deformity. There are many treatment options, but the severe forms of psoriasis are treated successfully with cytotoxic and biologic therapies. …”
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6390
Use of Hemadsorption in a Case of Pediatric Toxic Shock Syndrome
Published 2017-01-01“…A 5-year-old girl with Down’s syndrome presented with an inflamed area surrounding an insect bite, signs of systemic inflammation, and multiple organ failure. As previous attempts of immune modulation therapy were unsuccessful, renal replacement therapy was supplemented by the cytokine absorber CytoSorb. …”
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6391
Synthesis and Anti-Inflammatory Activity of New Alkyl-Substituted Phthalimide 1H-1,2,3-Triazole Derivatives
Published 2012-01-01“…The anti-inflammatory activity was determined by injecting carrageenan through the plantar tissue of the right hind paw of Swiss white mice to produce inflammation. All the compounds 3a–c and 5a–c exhibited an important anti-inflammatory activity; the best activity was found for the compounds 3b and 5c, which showed to be able to decrease by 69% and 56.2% carrageenan-induced edema in mice. …”
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6392
A Para-Canalicular Abscess Resembling an Inflamed Chalazion
Published 2013-01-01“…Purulence exited from the punctum lacrimale due to inflammation of the inferior canaliculus (canaliculitis). …”
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6393
Mothers’ experiences as legal guardian of children's phlebitis during hospitalization in Indonesia: A phenomenological study
Published 2025-01-01“…Background: Peripheral intravenous catheter (PIVC) insertion is a common procedure performed by nurses for hospitalized children, but phlebitis—an inflammation of the vein—is a frequent complication. …”
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6394
Recent advances in mesenchymal stem cell therapy for multiple sclerosis: clinical applications and challenges
Published 2025-02-01“…Multiple sclerosis (MS), a chronic autoimmune disorder of the central nervous system (CNS), is characterized by inflammation, demyelination, and neurodegeneration, leading to diverse clinical manifestations such as fatigue, sensory impairment, and cognitive dysfunction. …”
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6395
Bronchoalveolar Activation of Coagulation and Inhibition of Fibrinolysis during Ventilator-Associated Lung Injury
Published 2012-01-01“…Bronchoalveolar coagulopathy is a characteristic feature of pulmonary inflammation. We compared bronchoalveolar and systemic levels of coagulation in patients who did and patients who did not develop ventilator-associated lung injury (VALI). …”
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6396
Interaction of Cu(II) and Ni(II) with Ypk9 Protein Fragment via NMR Studies
Published 2014-01-01“…Here, we tested PK9-H with Cu(II) and Ni(II) ions, the former because it is an essential element ubiquitous in the human body, so its trafficking should be strictly regulated and one cannot exclude that Ypk9 may play a role in it, and the latter because, besides being a toxic element for many organisms and involved in different pathologies and inflammation states, it seems that the protein confers protection against it. …”
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6397
Predictive value of neutrophil-to-lymphocyte ratio for long-term adverse outcomes in cirrhosis patients post-transjugular intrahepatic portosystemic shunt
Published 2025-01-01“…This suggests that NLR is a valuable prognostic marker for long-term progression in these patients, highlighting the role of systemic inflammation.…”
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6398
Pharmacological targeting cGAS/STING/NF-κB axis by tryptanthrin induces microglia polarization toward M2 phenotype and promotes functional recovery in a mouse model of spinal cord...
Published 2025-11-01“…In this study, we found that tryptanthrin inhibited microglia-derived inflammation by promoting polarization to the M2 phenotype in vitro. …”
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6399
Exploring the microbiome-gut-testis axis in testicular germ cell tumors
Published 2025-01-01“…Dysbiosis in the gut or testicular microbiomes may contribute to altered immune responses, inflammation, and hormonal imbalances, potentially playing a role in the pathogenesis of TGCTs. …”
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6400
Resolution of depression: Antidepressant actions of resolvins
Published 2025-02-01“…These mediators reportedly play a pivotal role in the resolution of acute inflammation. In this review, we reveal that intracranial infusions of RvD1, RvD2, RvE1, RvE2, and RvE3 produce antidepressant-like effects in various rodent models of depression. …”
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