Intravenously Administered Human Umbilical Cord-Derived Mesenchymal Stem Cell (HucMSC) Improves Cardiac Performance following Infarction via Immune Modulation by Xiaoting Liang, Jing Liu, Mimi Li, Fang Lin, Rulin Zhuang, Qingshu Meng, Xiaoxue Ma, Yuanfeng Xin, Xin Gong, Zhiying He, Wei Han, Xiaohui Zhou, Zhongmin Liu

“…We hypothesized that intravenous (iv) administration of human umbilical cord-derived MSC (HucMSC) exerts systemic and local anti-inflammation effects, leading to improved heart function after MI. …”
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HSV-1 miR-H6 Inhibits HSV-1 Replication and IL-6 Expression in Human Corneal Epithelial Cells In Vitro by Fang Duan, Jingyu Liao, Qiang Huang, Yuhong Nie, Kaili Wu

“…Taken together, the data suggests that miR-H6 targeting of ICP4 inhibits HSV-1 productive infection and decreases interleukin 6 production in HCE, and this may provide an approach to prevent HSV-1 lytic infection and inhibit corneal inflammation.…”
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Interactions between and Shared Molecular Mechanisms of Diabetic Peripheral Neuropathy and Obstructive Sleep Apnea in Type 2 Diabetes Patients by Hong Shen, Junrong Zhao, Ying Liu, Guangdong Sun

“…Numerous molecular mechanisms have been documented that underlie diabetic peripheral neuropathy and OSA, including oxidative stress, inflammation, endothelin-1, vascular endothelial growth factor (VEGF), accumulation of advanced glycation end products, protein kinase C (PKC) signaling, poly ADP ribose polymerase (PARP), nitrosative stress, plasminogen activator inhibitor-1, and vitamin D deficiency. …”
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Epigenetic Markers of Renal Function in African Americans by Samantha M. Bomotti, Jennifer A. Smith, Alicia L. Zagel, Jacquelyn Y. Taylor, Stephen T. Turner, Sharon L. R. Kardia

“…The majority of methylation markers most significantly associated with eGFR (24 out of the top 30) appeared to function, at least in part, through pathways related to aging, inflammation, or cholesterol. However, six epigenetic markers were still able to significantly predict eGFR after adjustment for other risk factors. …”
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Why Does Pnemococcus Kill? by Yves Bergeron, Michel G Bergeron

“…This paper reviews the major bacterial virulence factors and pathogenesis steps that characterize fatal pneumococcal pneumonia, with a focus on the inflammation that was observed from the initial infection to death in an experimental murine pneumonia model. …”
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Serum amyloid A protein as a predictor of severity in coronavirus disease 2019-infected Egyptian patients by Dalia A.E.M.A.E.R. Negm, Wafaa M.A.E.-W. Elzefzafy, Sabah E.A. El Raheem, Nessren M.B. El Deen

“…Serum amyloid A (SAA) is an acute-phase protein secreted during the acute phase of inflammation and can be used to predict the severity of COVID-19 disease. …”
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The efficacy of an allosteric modulator of the alpha 7 nicotinic acetylcholine receptor in a murine model of stroke by Katherine Hernandez, Nathan Jones, Sterling B. Ortega

“…However, these agents present challenges such as a limited therapeutic window, incomplete reperfusion rates, risk of transformation, reperfusion-induced inflammation, and a lack of promoting neuroprotection. …”
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Inhibitory Effect of (2S)-Pinocembrin From Goniothalamus macrophyllus on the Prostaglandin E2 Production in Macrophage Cell Lines by Hilwan Yuda Teruna, Kamal Rullah, Rudi Hendra, Rahayu Utami, Deri Islami, Siti Munirah Mohd Faudzi, Mohd Fadhlizil Fasihi Mohd Aluwi, Kok Wai Lam

“…This plant has been used traditionally as an herbal medicine to alleviate inflammation. (2S)-PCB was isolated from the stem bark of G. macrophyllus by defatting with n-hexane followed by maceration with methanol. …”
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Sarcoidosis and Non-small Cell Lung Cancer: Expression of miR-145, miR-301, and miR-449 by Negin Khosravi, Abdolreza Mohamadnia, Changiz Ahmadi Zadeh, Naghmeh Bahram, Saeid Ghorbian

“…Background: In the field, sarcoidosis is a condition characterized by inflammation, with an unknown origin often impacting the lungs and chest lymph nodes. …”
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Kounis Syndrome Secondary to Medicine-Induced Hypersensitivity by Parackrama Karunathilake, Udaya Ralapanawa, Thilak Jayalath, Shamali Abeyagunawardena

“…Kounis syndrome is mediated by mast cells that interact with macrophages and T-lymphocytes, causing degranulation and inflammation with cytokine release. It is a life-threatening condition that has many trigger factors and is most commonly caused by medicines. …”
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Unusual Localization of an Emergent Bacterium, Raoultella ornithinolytica by Michele Cavaliere, Guido Bartoletti, Pasquale Capriglione, Antonella Miriam Di Lullo, Gaetano Motta, Maurizio Iengo, Elena Cantone

“…After ten days of treatment with oral ciprofloxacin and topic levofloxacin, there was the complete resolution of pain and inflammation. Raoultella ornithinolytica must be taken into consideration as an emergent cause of human infection, also in case of external otitis. …”
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Influence of immune cells and inflammatory factors on Alzheimer’s disease axis: evidence from mediation Mendelian randomization study by Linzhu, Jianxin Zhang, Wenhui Fan, Chen Su, Zhi Jin

“…While the exact etiology of AD remains unclear, immune inflammation is known to play a significant role in the disease. …”
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Konjac-mulberry leaf compound powder alleviates OVA-induced allergic rhinitis in BALB/c mice by Yiyun Zhang, Jinxing Wang, Qi Zhang, Liling Deng, Siyao Miao, Geng Zhong

“…It is found to be good for anti-inflammation. However, its precise anti-allergic rhinitis effect and mechanism remain unknown. …”
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Determination of the levels of some selected metals in ocimum lamiifolium in Wolaita Zone, Southern Ethiopia by Eyob Yishak, Teferi Tademe Dadebo

“…Ex Benth (Damakese, in Amharic) is one of the well celebrated and most widely used home remedy for the treatment of a disease locally known as “Mitch” which is characterized by headache, fever, inflammation, joint pain, sweat, loss of appetite, etc. …”
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Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis by Xiaofan Sun, Yue Li, Juan Du, Fangshu Liu, Caiping Wu, Weihao Xiao, Guopan Yu, Xiaowei Chen, Robert Peter Gale, Hui Zeng

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MARCHF8-mediated ubiquitination via TGFBI regulates NF-κB dependent inflammatory responses and ECM degradation in intervertebral disc degeneration. by Xingpeng Zhang, Guang Li, Fang Tan, Tao Yu, Chengping Xu, Kai Li, Feng Zhang, Meiyan Zhang, Jian Wang

“…<h4>Conclusion</h4>TGFBI, modulated by MARCHF8, significantly influences IDD progression by affecting NP cell apoptosis, ECM degradation, and inflammation through the NF-κB signaling pathway.…”
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Graves’ Ophthalmopathy: VISA versus EUGOGO Classification, Assessment, and Management by Jesús Barrio-Barrio, Alfonso L. Sabater, Elvira Bonet-Farriol, Álvaro Velázquez-Villoria, Juan C. Galofré

“…The VISA (vision, inflammation, strabismus, and appearance), and the European Group of Graves’ Orbitopathy (EUGOGO) classifications are the two widely used grading systems conceived to assess the activity and severity of GO and guide the therapeutic decision making. …”
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Utility of Tetrahydrobiopterin Pathway in the Assessment of Diabetic Foot Ulcer: Significant and Complex Interrelations by Marwan Al-Nimer, Rawa Ratha, Taha Mahwi

“…Tetrahydrobiopterin biomarkers are predictors of DFUs and the significant correlation of neopterin with red distribution width and erythrocyte sedimentation rate indicating the role of neopterin in the vascular and inflammation concerns of noninfected DFUs.…”
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Cytokine-armed pyroptosis induces antitumor immunity against diverse types of tumors by Sara Orehek, Taja Železnik Ramuta, Duško Lainšček, Špela Malenšek, Martin Šala, Mojca Benčina, Roman Jerala, Iva Hafner-Bratkovič

“…Additionally, we show that the intratumoral introduction of armed pyroptosis provides protection against distant tumors and proves effective across various tumor types without inducing systemic inflammation. Deconstructed inflammasomes thus serve as a powerful, tunable, and tumor-agnostic strategy to enhance antitumor response, even against the most resilient types of tumors.…”
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Circular RNA circ-CARD8 regulates alveolar macrophage pyroptosis through the miR-580-3p/CARD8 pathway in acute lung injury. by Sida Chen, Ling Wen, Yumei Wu, Shan Xiao, Yuting Lai, Jintao Ou, Yan Shen

“…Pyroptosis is linked to the development of acute lung injury (ALI), and circular RNAs (circRNAs) play a role in ALI-related inflammation. However, the mechanisms by which circRNAs contribute to macrophage pyroptosis in ALI remain unclear. …”
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