Bioactivity-guided isolation and molecular modeling of the anti-inflammatory constituents from the leaves of Duranta erecta Linn. by Marina Sobhy, Farid N. Kirollos, Sameh F. AbouZid, Nasser S. M. Ismail, Riham A. El-Shiekh, Essam Abdel-Sattar

“…Overall, the data reported in this study add to our understanding of the pharmacological properties of the examined plant and Duranterectoside A (1) and pave the way for future research and investigation in inflammation and drug discovery.…”
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Ligands of CD6: roles in the pathogenesis and treatment of cancer by Mikel Gurrea-Rubio, Feng Lin, Max S. Wicha, Yang Mao-Draayer, David A. Fox

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Sustained remission in large-Vessel vasculitis: Do they ever burn out? by Sakir Ahmed, Padmanabha Shenoy, Debashish Danda, Ramnath Misra

“…Various imaging techniques exhibit vessel wall inflammation in clinically quiescent disease. Relapse rate seems to correlate with the rate of steroid reduction. …”
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Antilipoxygenase and Anti-Inflammatory Activities of Streblus asper Leaf Extract on Xylene-Induced Ear Edema in Mice by Kanathip Singsai, Pimchanok Charoongchit, Waritsara Chaikaew, Nirut Boonma, Pitsinee Fhanjaksai, Karitta Chaisatan

“…However, further studies are required to evaluate these effects and the additional potential of the plant that might be beneficial for the development of pharmaceutical products that prevent and treat inflammation.…”
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Vedolizumab for inflammatory bowel diseasesI by Igor L. Khalif, M. V. Shapina

“…The vedolizumab is anti-α4β7-integrin humanized class IgG1 antibodies which suppresses migration of leukocytes in intestinal tissue, interfering thereby with development of pathologic inflammation. GEMINI-1 study of ulcerative colitis has demonstrated efficacy of the drug in remission induction (clinical response rate of 47,1% of patients, clinical remission of 16,9% and endoscopic remission of 40,9% at the 6th week) and in remission maintenance (percent of patients in clinical remission at 52nd week at drug injection every 4 weeks - 44,8%). …”
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Evaluation of T memory cells in knee osteoarthritis patients by Rehab S. Mohamed, Alaa M. Hashim, Abdelhafeez M. Moshrif, Ali Sobhy

“…CD4+ T cells may serve a role in inducing inflammation in the early stages of OA, as well as being instrumental in causing inflammatory damage to the articular cartilage in the latter stages.…”
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Immune Vulnerability of Infants to Tuberculosis by Koen Vanden Driessche, Alexander Persson, Ben J. Marais, Pamela J. Fink, Kevin B. Urdahl

“…Modalities aimed at reducing inflammation, which may be beneficial for adjunctive therapy of some forms of TB in older children and adults, may be of no benefit or even harmful in infants who manifest much less inflammatory disease.…”
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STAPHYLOCOCCAL INFECTION IN DOGS (DIAGNOSIS, TREATMENT AND PREVENTION) by V. B. Rudenko, P. A. Rudenko, S. G. Semushina, I. A. Pakhomova

“…Therefore, it is rather difficult to apply tools of specific protection and prophylaxis. Skin and mucosa inflammation is the most common pathological condition observed in dogs. …”
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Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21. by Suresh Pallikkuth, Luca Micci, Zachary S Ende, Robin I Iriele, Barbara Cervasi, Benton Lawson, Colleen S McGary, Kenneth A Rogers, James G Else, Guido Silvestri, Kirk Easley, Jacob D Estes, Francois Villinger, Savita Pahwa, Mirko Paiardini

“…Remarkably, increased levels of Th17 cells were associated with reduced levels of intestinal T cell proliferation, microbial translocation and systemic activation/inflammation in the chronic infection. In conclusion, IL-21-treatment in SIV-infected RMs improved mucosal immune function through enhanced preservation of Th17 cells. …”
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The neuroscience in breast cancer: Current insights and clinical opportunities by Jia-feng Wang, Meng-chuan Wang, Lei-lei Jiang, Neng-ming Lin

“…Interaction between the nervous system and breast cancer can influence tumor initiation, growth, invasion, metastasis, reverse resistance to drugs, promote inflammation in tumors, and impair the immune system's ability to combat cancer. …”
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Exposure to Common Food Additive Carrageenan Alone Leads to Fasting Hyperglycemia and in Combination with High Fat Diet Exacerbates Glucose Intolerance and Hyperlipidemia without E... by Sumit Bhattacharyya, Leo Feferman, Terry Unterman, Joanne K. Tobacman

“…Effects on fasting blood glucose, glucose tolerance, lipid parameters, weight, glycogen stores, and inflammation were compared. Results. Exposure to carrageenan led to glucose intolerance by six days and produced elevated fasting blood glucose by 23 weeks. …”
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TLR-8, TNF-α, and ESR-1α Gene Polymorphism Susceptibility in Onset of Arthritis by Maryam Mukhtar, Nadeem Sheikh, Andleeb Batool, Tayyaba Saleem, Muhammad Babar Khawar, Mavra Irfan, Saira Kainat Suqaina

“…Arthritis is a genetic disorder characterized by bones and joint degradation assisted by severe pain and inflammation. It is evident by the studies that 0 candidate genes variations play vital role in its development and progression. …”
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Impact of Vitamin D on Skin Aging, and Age-Related Dermatological Conditions by Sankalya S. Ambagaspitiya, Gayan A. Appuhamillage, Sunil J. Wimalawansa

“…Vitamin D, in turn, protects the skin from oxidative stress, inflammation, and DNA damage, thereby delaying both chronological and photo-aging. …”
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The Role of Cyclooxygenase in Multiplication and Reactivation of HSV-1 in Vestibular Ganglion Neurons by Yuehong Liu, Shufeng Li, Zhengmin Wang

“…Reactivation of latent herpes simplex type 1 (HSV-1) and nerve inflammation have been shown to be involved in vertigo-related vestibular pathogenesis. …”
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Respiratory diseases in young cattle by T. S. Ermilova, M. A. Samburova, O. V. Kasharnaya, E. A. O. Salimzade

“…It is a respiratory pathology characterized by inflammation of both the bronchi and lungs. As a rule, such disease types are most common in industrial animal husbandry, they are widespread and cause significant economic damage to the dairy and beef cattle breeding industries. …”
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The Regulation between CD4+CXCR5+ Follicular Helper T (Tfh) Cells and CD19+CD24hiCD38hi Regulatory B (Breg) Cells in Gastric Cancer by Ying Zhang, Jun Wu, Haibo Zhang, Chen Wu

“…T follicular helper (Tfh) cells and regulatory B (Breg) cells are reported to play essential roles in humoral immunity, especially in inflammation, autoimmune diseases, and cancer. Hence, we sought to investigate the involvement of CXCR5+CD4+ Tfh cells and CD19+CD24hiCD38hi Breg cells in gastric cancer. …”
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Nicotinamide mononucleotide boosts the development of bovine oocyte by enhancing mitochondrial function and reducing chromosome lagging by Shu Hashimoto, Udayanga Gamage, Yuki Inoue, Hisataka Iwata, Yoshiharu Morimoto

“…Abstract Nicotinamide adenine dinucleotide (NAD(H)) and its metabolites function as crucial regulators of physiological processes, allowing cells to adapt to environmental changes such as nutritional deficiencies, genotoxic factors, disruptions in circadian rhythms, infections, inflammation, and exogenous substances. Here, we investigated whether elevated NAD(H) levels in oocytes enhance their quality and improve developmental competence following in vitro fertilization (IVF). …”
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Unraveling the microbial mysteries: gut microbiota’s role in ulcerative colitis by Keyu Ren, Chunming Yong, Yanchun Jin, Shanwei Rong, Kuijin Xue, Bin Cao, Hongyun Wei

“…Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by persistent inflammation of the colon. Recent research has highlighted the significant role of gut microbiota in the pathogenesis and treatment of UC. …”
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Chronic-Alcohol-Abuse-Induced Oxidative Stress in the Development of Acute Respiratory Distress Syndrome by Yan Liang, Samantha M. Yeligar, Lou Ann S. Brown

“…Chronic alcohol ingestion increases the risk of developing acute respiratory distress syndrome (ARDS), a severe form of acute lung injury, characterized by alveolar epithelial and endothelial barrier disruption and intense inflammation. Alcohol abuse is also associated with a higher incidence of sepsis or pneumonia resulting in a higher rate of admittance to intensive care, longer inpatient stays, higher healthcare costs, and a 2–4 times greater mortality rate. …”
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Astaxanthin as a potential therapeutic agent for knee osteoarthritis: A review of mechanisms and clinical evidence by Sidra Sabir, AHM Mahmudur Rahman, Abdul Haseeb Bhutta

“…Results: The review identified several key mechanisms by which astaxanthin exerts its therapeutic effects, including reducing oxidative stress, attenuating inflammation, and preserving cartilage integrity. Clinical studies also provided promising evidence of its efficacy in alleviating symptoms and improving joint function in patients with KOA. …”
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