Modelling the Transmission Dynamics of Meningitis among High and Low-Risk People in Ghana with Cost-Effectiveness Analysis by Nicholas Kwasi-Do Ohene Opoku, Reindorf Nartey Borkor, Andrews Frimpong Adu, Hannah Nyarkoah Nyarko, Albert Doughan, Edwin Moses Appiah, Biigba Yakubu, Isabel Mensah, Samson Pandam Salifu

“…Meningitis is an inflammation of the meninges, which covers the brain and spinal cord. …”
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Metabolic reprogramming of naïve regulatory T cells by IL-7 and IL-15 promotes their persistence and performance upon adoptive transfer by Jessica Filoni, Arianna Ferrari, Tatiana Jofra, Anna Rita Putignano, Lorenzo Da Dalt, Susanna Cesarano, Carla Di Dedda, Fabrizia Bonacina, Federica Marchesi, Danilo Norata, Chiara Bonini, Lorenzo Piemonti, Paolo Monti

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Association of high complement and low immunoglobulins with the clinical symptoms of patients with fibromyalgia by Satoshi Izuno, Masako Hosoi, Kozo Anno, Takahiro A. Kato, Nobuyuki Sudo, Kazufumi Yoshihara

“…Abstract Background Fibromyalgia (FM) is a disease characterized by chronic widespread pain concomitant with various symptoms such as fatigue and anxiety. Although chronic inflammation has been implicated in the immunological abnormalities of FM, there are few human studies on complement and immunoglobulins. …”
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The Protective Effect of Beraprost Sodium on Diabetic Cardiomyopathy through the Inhibition of the p38 MAPK Signaling Pathway in High-Fat-Induced SD Rats by Jie Li, Li Peng, Hong Du, Yangtian Wang, Bin Lu, Yixin Xu, Xiaozhen Ye, Jiaqing Shao

“…After 8 weeks, we explored the role of the p38 MAPK signaling pathway in inflammation, oxidative stress, cardiac morphology, and myocardial apoptosis. …”
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A Case of Lymphocytic Myocarditis with Eosinophilic Degranulation Successfully Treated with Steroid Therapy by Tomoko Inoue, Fusako Sera, Shunsuke Nishimura, Kei Nakamoto, Yasumasa Tsukamoto, Isamu Mizote, Tomohito Ohtani, Shungo Hikoso, Yoshihiko Ikeda, Yumiko Hori, Hatsue Ishibashi-Ueda, Eiichi Morii, Tetsuo Minamino, Yasushi Sakata

“…In eosinophilic myocarditis, eosinophil degranulation has been recognized as an important finding associated with progression of inflammation and myocardial damage. However, no attention has been paid to the presence and clinical implications of eosinophil degranulation in lymphocytic myocarditis. …”
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Short-Chain Fatty Acids Promote Immunotherapy by Modulating Immune Regulatory Property in B Cells by Cai-Jie Zhou, Bai-Ling Xie, Hai-Yang Han, Yin Wang, Yong-Hua Wang, Jing-Yi Hong, Yi-Xia Wei, Zhi-Gang Liu, Yan Feng, Gui Yang, Ping-Chang Yang

“…The dysfunction of regulatory B cells (Breg) may result in immune inflammation such as allergic rhinitis (AR); the underlying mechanism is not fully understood yet. …”
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Revealing study and breeding implications for production traits and tail characteristics in Simmental cattle by GWAS by Jie Wang, Na Shen, Kaisen Zhao, Jiayu Liao, Genglong Jiang, Jianghai Xiao, Xianbo Jia, Wenqiang Sun, Songjia Lai

“…Interestingly, candidate genes IL1RAP, AQP9, ITPR2, and PKD2 were also associated with metabolic inflammation in cattle tails. These genetic markers offer valuable insights into the traits of Simmental cattle, facilitating the development of molecular breeding strategies to enhance production value and provide references for breeding programs.…”
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Ultrasound B-Scan for Posterior Segment and Extraocular Evaluation in Ocular Cysticercosis by Bhatt VD, Bhatt KD, Bhatt DC, Dabir S, Sheth JU, Berendschot TTJM, Erckens RJ, Webers CAB

“…Intra-vitreous cysticercosis (n=9) exhibited thin-walled cysts with minimal inflammation, progressing to thickened cyst walls in the late stages. …”
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Patient‐Reported Fatigue Associated with Joint Histopathology in Rheumatoid Arthritis by Diyu Pearce‐Fisher, Melanie H. Smith, Bella Y. Mehta, Edoardo Spolaore, Edward DiCarlo, Dongmei Sun, Susan M. Goodman

“…SLH was affected by synovial lymphocytic inflammation. In multivariable models, female sex, DAS28‐ESR, and SLH were all associated with higher fatigue. …”
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A narrative review about cognitive impairment in Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD): Another matter to face through a holistic approach by Marica Meroni, Miriam Longo, Erika Paolini, Paola Dongiovanni

“…Indeed, cognitive decline in MASLD translates in low concentration and processing speed, reduced memory, sleepiness but also anxiety and depression. Chronic systemic inflammation, hyperammonemia, genetic background and intestinal dysbiosis possibly contribute to the cognitive decline in MASLD patients. …”
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Role of acute respiratory diseases in pathogenesis of distal limb infections in cattle by A. D. Alekseev, O. G. Petrova, M. I. Barashkin, I. M. Milshtein, V. D. Moskvin

“…Low molecular weight circulating immune complexes settle in various organs and tissues of the body, lead to inflammation and damage the normal tissue structure. …”
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<i>Aspergillus oryzae</i> Fermented <i>Plumula Nelumbinis</i> Against Atopic Dermatitis Through AKT/mTOR and Jun Pathways by Fengfeng Chen, Jing Liu, Xinwei Yu, Honglei Jia, Cheng Yang, Bingtian Zhao

“…Moreover, FPN can also alleviate SDS-induced inflammation in zebrafish. It is also found that the anti-inflammatory activity of <i>Plumula Nelumbinis</i> was enhanced by <i>Aspergillus oryzae</i> fermentation, and the oil phase of the fermentation product showed better activity, which may be due to microbial fermentation changing the structure of the original alkaloids. …”
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Associations between White Blood Cell Count and the Development of Incidental Nonalcoholic Fatty Liver Disease by Goh Eun Chung, Jeong Yoon Yim, Donghee Kim, Min-Sun Kwak, Jong In Yang, Su Jin Chung, Sun Young Yang, Joo Sung Kim

“…Chronic low-grade inflammation is thought to be associated with the pathogenesis of nonalcoholic fatty liver disease (NAFLD). …”
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From gut to liver: Exploring the crosstalk between gut-liver axis and oxidative stress in metabolic dysfunction-associated steatotic liver disease by Mi Zhou, Jianyu Lv, Xinli Chen, Yujie Shi, Guanqun Chao, Shuo Zhang

“…Our analysis reveals several key findings: (1) Bile acid dysregulation can trigger oxidative stress through enhanced ROS production in hepatocytes and Kupffer cells, leading to mitochondrial dysfunction and lipid peroxidation; (2) Gut microbiota dysbiosis disrupts intestinal barrier function, allowing increased translocation of endotoxins like LPS, which activate inflammatory pathways through TLR4 signaling and promote oxidative stress via NADPH oxidase activation; (3) The redox-sensitive transcription factors NF-κB and Nrf2 serve as crucial mediators in the gut-liver axis, with NF-κB regulating inflammatory responses and Nrf2 orchestrating antioxidant defenses; (4) Oxidative stress-induced damage to intestinal barrier function creates a destructive feedback loop, further exacerbating liver inflammation and disease progression. These findings highlight the complex interrelationship between gut-liver axis dysfunction and oxidative stress in MASLD pathogenesis, suggesting potential therapeutic targets for disease management.…”
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Impaired Growth during Childhood in Patients with Primary Ciliary Dyskinesia by Tamara Svobodová, Jana Djakow, Daniela Zemková, Adam Cipra, Petr Pohunek, Jan Lebl

“…Primary ciliary dyskinesia (PCD) leads to recurrent/chronic respiratory infections, resulting in chronic inflammation and potentially in chronic pulmonary disease with bronchiectasis. …”
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Platelet-rich fibrin and silver nano-particles loaded chitosan treatment for post- laminectomy epidural scar adhesions: in vivo rats study model by Samah Fouad, Awad Rizk, Esam Mosbah, Mostafa M. Nabeeh, Walaa Awadin, Ayman S. Elmezayyen, Ekramy Elmorsy, Adel Zaghloul

“…Results Data revealed that epidural scar adhesion, scaring, arachnoid involvement, dural thickness, as well as inflammation and TGFβ-1and IL-6 coding genes expression were significantly reduced in PRF group, Chi/Ag-NPs group, and combined group compared to the laminectomy group. …”
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Difference in the Vitreal Protein Profiles of Patients with Proliferative Diabetic Retinopathy with and without Intravitreal Conbercept Injection by Chen Zou, Minjie Zhao, Jingjing Yu, Dandan Zhu, Yunzhi Wang, Xinping She, Yanan Hu, Zhi Zheng

“…In addition to decreasing the intravitreal vascular endothelial growth factor level, IVC may alter the vitreal protein profile in patients with PDR, with the differentially regulated proteins involved in the immune response, platelet degranulation, complement activation, and inflammation.…”
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Long-Term Surgical Outcomes of Glaucoma Drainage Implants in Eyes with Preoperative Intraocular Pressure Less than 19 mmHg by Shahin Hallaj, Jae-Chiang Wong, Lauren E. Hock, Natasha Nayak Kolomeyer, Aakriti G. Shukla, Michael J. Pro, Marlene R. Moster, Jonathan S. Myers, Reza Razeghinejad, Daniel Lee

“…Postop complications (23.9%) included GDI exposure (7.5%), inflammation (4.5%), shallow anterior chamber (4.5%), and strabismus (1.5%). …”
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Silica Nanoparticles Loaded With Selenium Quantum Dots Reduce Myocardial Ischemia-Reperfusion Injury by Alleviating Ferroptosis and Mitochondrial Dysfunction by Li T, Yang B, Liu X, Shi D, Wang Z, Chen Y, Shen C

“…These effects collectively resulted in reduced myocardial loss, inflammation, and fibrosis following IR injury. Compared to PSN alone, Se@PSN showed superior therapeutic efficacy against IR injury.Conclusion: Se@PSN exhibit great potential in reducing ferroptosis and protecting mitochondrial function, making them a promising therapeutic approach for the treatment of myocardial IR injury. …”
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Efficacy of oral irrigators compared to other interdental aids for managing peri-implant diseases: a systematic review by Gargi Gandi, Bhoomika Sai Laxmi Masanam, Ananya Sudhakaran Nair, Nidhi Semani, Aditi Chopra, Venkitachalam Ramanarayan

“…Conclusion Oral irrigators along with toothbrushing were found to be more effective in removing microbial plaque around implants and controlling peri-implant inflammation compared to mechanical brushing alone. The reduction in BOP was better with the use of oral irrigation compared to floss and interdental brush.…”
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