Karakteristik Klinis Glaukoma Uveitis di Pusat Mata Nasional Rumah Sakit Cicendo Bandung Tahun 2021-2022 by Refandi Dwi Andrianto, Elsa Gustianty, Raden Maula Rifada

“…Uveitic glaucoma is a complication of uveitis that can occur due to severe intraocular inflammation. Objective: To determined the clinical characteristics of uveitic glaucoma based on clinical features and management at the Cicendo Hospital National Eye Center from 2021 until 2022. …”
Get full text

Perforated Gallbladder into the Abdominal Wall by M. Puglisi, M. Peter, B. Egger

“…Anatomical pathology analysis found chronic inflammation and excluded malignancy. The postoperative follow-up was uneventful. …”
Get full text

Characteristics of primary biliary cirrhosis in British Columbia's First Nations population by Laura Arbour, Rosemarie Rupps, Leigh Field, Paul Ross, Anders Erikson, Harvey Henderson, Warren Hill, Eric M Yoshida

“…Primary biliary cirrhosis (PBC) is a rare, autoimmune liver disorder characterized by progressive destruction of intrahepatic bile ducts, that results in portal inflammation, scarring, cirrhosis and, eventually, liver failure. …”
Get full text

Treatment of the Induration of the Soft Tissue of the Lower Eyelids After Accidental Oil Injections by Vladimir Safronov, MD, PhD

“…The author presents a case of a 51-year-old woman, injected with unknown oil solution into the lower eyelid skin by the local dermatologist. Inflammation and induration of the skin of the lower periorbital region have occurred after these injections. …”
Get full text

Mitophagy in ischemic heart disease: molecular mechanisms and clinical management by Shujuan Xu, Zihan Wang, Fan Guo, Yehao Zhang, Han Peng, Huiyu Zhang, Zixin Liu, Ce Cao, Gaojie Xin, Yuan Yuan Chen, Jianhua Fu

“…We conclude that mitophagy affects ischemic heart disease by promoting cardiomyocyte hypertrophy and fibrosis, the progression of oxidative stress, the development of inflammation, and cardiomyocyte death, and that the specific mechanisms of mitophagy are worthy of further investigation.…”
Get full text

Medication-Related Osteonecrosis of the Jaw: New Insights into Molecular Mechanisms and Cellular Therapeutic Approaches by Thomas Lombard, Virginie Neirinckx, Bernard Rogister, Yves Gilon, Sabine Wislet

“…In parallel to pharmacological treatments, MSC grafts appeared to be beneficial in the treatment of MRONJ, in multiple aspects: (1) recruitment and stimulation of local or regional endogenous cells to differentiate into osteoblasts and thus bone formation, (2) beneficial impact on bone remodeling, and (3) immune-modulatory properties that decrease inflammation. In this context, the second objective of this manuscript would be to summarize the molecular regulatory events controlling osteogenic differentiation, bone remodeling, and osteoimmunology and potential beneficial effects of MSC related to those aspects, in order to apprehend MRONJ and to develop new therapeutic approaches.…”
Get full text

Traffic Control of Bacteria-Derived Molecules: A New System of Host-Bacterial Crosstalk by Hiroaki Konishi, Mikihiro Fujiya, Yutaka Kohgo

“…Conversely, commensal bacteria and probiotics, which symbiotically confer health benefits on the host organisms, can lodge in the host intestinal tract without inducing intestinal inflammation. Recent advances in investigations concerning host-microbial interactions have shown that some effector molecules secreted from beneficial bacteria activate cell survival pathways, such as those mediated by p38 MAPK and Akt, and bring health benefits to mammalian hosts. …”
Get full text

Iron metabolism in rheumatic diseases by Aliakbar Givian, Amin Azizan, Ahmadreza Jamshidi, Mahdi Mahmoudi, Elham Farhadi

“…Altered iron homeostasis can contribute to disease progression through ROS production, fibrosis, inflammation, abnormal bone homeostasis, NETosis and cell senescence. …”
Get full text

Evaluation and molecular modelling of bis-Schiff base derivatives as potential leads for management of diabetes mellitus by Daoud Safa, Thiab Samar, Jazzazi Taghreed M. A., Al-Shboul Tareq M. A., Ullah Saeed

“…Toward this end, six bis-biphenyl-salicylaldehyde Schiff base derivatives have been evaluated for their α-glucosidase inhibition, antiglycation and anti-inflammation potentials. Four compounds (compounds 2–5) showed an excellent α-glucosidase inhibitory effect superior to that produced by acarbose. …”
Get full text

From Homeostasis to Neuroinflammation: Insights into Cellular and Molecular Interactions and Network Dynamics by Ludmila Müller, Svetlana Di Benedetto, Viktor Müller

“…We examine how neuroimmune interactions, mediated through these cellular actors and signaling pathways, create complex networks that regulate CNS functionality and respond to injury or inflammation. To further elucidate these dynamics, we provide insights using a multilayer network (MLN) approach, highlighting the interconnected nature of neuroimmune interactions under both inflammatory and homeostatic conditions. …”
Get full text

Severe Presentation of Nontypeable Haemophilus influenzae (NTHi) Infection in a Previously Healthy Toddler by Eiman Al Boloushi, Abdulla Al Amri, Ghassan Ghatasheh, Huda Al Dhanhani

“…Cellulitis is the inflammation of the skin and subcutaneous tissue. It is usually caused by Gram-positive organisms such as Staphylococcus and Streptococcus pyogenes infection. …”
Get full text

Prevalence of Plaque Induced Gingivitis Among Dental Students in College of Dentistry, Hawler Medical University. by Zainab Salim Mahmood, Qehraman Ismayil Ahmed, Ahmed Luqman Saifullah

“… Background and objective: Gingival inflammation in response to bacterial plaque accumulation is considered the key risk factor for the onset of periodontitis. …”
Get full text

Metabolic Syndrome, Chronic Kidney, and Cardiovascular Diseases: Role of Adipokines by Manfredi Tesauro, Maria Paola Canale, Giuseppe Rodia, Nicola Di Daniele, Davide Lauro, Angelo Scuteri, Carmine Cardillo

“…Obesity and MetS affect renal physiology and metabolism through mechanisms which include altered levels of adipokines such as leptin and adiponectin, oxidative stress, and inflammation. Secretory products of adipose tissue also deeply and negatively influence endothelial function. …”
Get full text

Impact of Fixed Orthodontic Appliances on Blood Count and High-Sensitivity C-Reactive Protein Levels by Jiwanasha Manish Agrawal, Vidyesh Nadkerny, Anurag Tiwari, Mahesh Ghadage, Avantika Jadhav, Chetan Sharma, Dipooja Patil

“…However, their impact on systemic inflammation and hematological parameters remains under-explored. …”
Get full text

The impact of environmental factors on the immunopathogenesis of osteoporosis: A systematic review by Prabowo Nurhasan Agung, Soetrisno, Nurwati Ida, Ardyanto Tonang Dwi, Poncorini Eti, Nurudhin Arief, Dirgahayu Paramasari

“…The review's findings indicate that exposure to environmental pollutants triggers systemic inflammation and oxidative stress, contributing to an imbalance between bone formation and resorption. …”
Get full text

Diabetic Muscle Infarction: A Rare Complication of Long-Standing and Poorly Controlled Diabetes Mellitus by Shridhar N. Iyer, Almond J. Drake, R. Lee West, Robert J. Tanenberg

“…A muscle biopsy demonstrated coagulation necrosis in skeletal muscle and inflammation and infarction in the walls of small blood vessels. …”
Get full text

Oral Verruciform Xanthoma within Lichen Planus: A Case Report and Literature Review by Vasileios I. Theofilou, Alexandra Sklavounou, Prokopios P. Argyris, Evanthia Chrysomali

“…The occurrence of the lesion in patients with immune-mediated mucocutaneous diseases may suggest a role of localized epithelial cell damage and chronic inflammation in its pathogenesis. Case Report. A case of verruciform xanthoma on the tongue of a 56-year-old female with oral lichen planus is reported. …”
Get full text

Efficacy of melatonin treatment in a cystic fibrosis mouse model of airway infection by Kristen R. Schaefer, Sara Rogers, Zachary Faber, Thomas J. Kelley

“…Mice treated in drinking water for 1 week had improved bacterial clearance but no improvement in inflammation. Wild type (WT) control mice showed no response to melatonin treatment suggesting melatonin is eliciting a CF-specific response in this model. …”
Get full text

Assessment of Some Heavy Metals and Trace Elements in a Sample of Patients with Viral Hepatitis in Baghdad by Najlaa Fattah-Allah Rasheed, Hind Salman Jassim, Ahmad Saadi Hassan

“…Impairment of liver functions disrupts trace element metabolism, causing oxidative stress, which subsequently leads to liver inflammation and fibrosis. This study aims to evaluate zinc (Zn), copper (Cu), iron (Fe), cadmium (Cd), and lead (Pb) levels in chronic viral hepatitis (HBV or HCV) patients in Baghdad. …”
Get full text

Follistatin like-1 aggravates silica-induced mouse lung injury by Yinshan Fang, Si Zhang, Xiaohe Li, Fangxin Jiang, Qiao Ye, Wen Ning

“…The induced Fstl1 regulated inflammation response via activation of nod-like receptor family, pyrin domain containing 3v (NLRP3) inflammasome-mediated IL-1β production from macrophages. …”
Get full text