PYR-41 and Thalidomide Impair Dendritic Cell Cross-Presentation by Inhibiting Myddosome Formation and Attenuating the Endosomal Recruitments of p97 and Sec61 via NF-κB Inactivation... by Xiang You, Dan Dan Xu, Di Zhang, Jie Chen, Feng Guang Gao

“…PYR-41 and thalidomide have therapeutic effects on inflammation-associated diseases with side effects such as tumorigenesis. …”
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A Case of Acute Disseminated Encephalomyelitis in a Middle-Aged Adult by Nicole Mahdi, Peter A. Abdelmalik, Mark Curtis, Barak Bar

“…He underwent a brain biopsy showing widespread white matter inflammation secondary to demyelination. At discharge, his neurological exam had significantly improved with continued steroid treatment and four months later, he was able to perform his ADLs. …”
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Anti-SARS-CoV-2 Biotherapeutics and Chemotherapeutics: An Insight into Product Specifications and Marketing Dynamics by Vijay Kotra, Dinakar Mallem, Anil Kumar Kanuri, Mahesh Reddy Burra, Shaik Nyamathullah, Looi Shu Ying, Khairul Anwar Husain, Ravi Varala, Madhadevi Sudhakar, Khang Wen Goh, Toong Hai Sam, Long Chiau Ming

“…These drugs have been repurposed for use in COVID-19 due to their antiviral properties and ability to reduce inflammation. The COVID-19 death cases have significantly reduced because of tested efficacy of advanced biotherapeutics and chemotherapeutics. …”
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T2-Weighted Cardiac Magnetic Resonance Imaging of Edema in Myocardial Diseases by Yasuo Amano, Masaki Tachi, Hitomi Tani, Kyoichi Mizuno, Yasuhiro Kobayashi, Shinichiro Kumita

“…T2-weighted MRI of edema identifies myocardial edema associated with ischemia, inflammation, vasculitis, or intervention in the myocardium and provides information complementary to delayed-enhancement MRI.…”
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HIV RNA Suppression and Immune Restoration: Can We Do Better? by Marilia Rita Pinzone, Michelino Di Rosa, Bruno Cacopardo, Giuseppe Nunnari

“…., low levels of plasma HIV RNA) has been related with higher levels of chronic inflammation and all-cause mortality. The sources of residual viremia are not yet completely known, even though the most important one is represented by latently infected cells. …”
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Multicentric Castleman’s Disease in a Child Revealed by Chronic Diarrhea by Sarra Benmiloud, Sana Chaouki, Samir Atmani, Moustapha Hida

“…It presents with fever, systemic symptoms, generalized lymphadenopathy, and laboratory markers of inflammation. Its treatment is not standardized and its prognosis is poor. …”
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Role of extracellular vesicles in the pathogenesis of mosquito-borne flaviviruses that impact public health by Pedro Pablo Martínez-Rojas, Verónica Monroy-Martínez, Blanca H. Ruiz-Ordaz

“…This review focuses on the roles of extracellular vesicles in the pathogenesis of mosquito-borne flavivirus diseases: how they contribute to viral cycle completion, cell-to-cell transmission, and cellular responses such as inflammation, immune suppression, and evasion, as well as their potential use as biomarkers or therapeutics (antiviral or vaccines). …”
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Recombinant Human Brain Natriuretic Peptide Attenuates Myocardial Ischemia-Reperfusion Injury by Inhibiting CD4+ T Cell Proliferation via PI3K/AKT/mTOR Pathway Activation by Kun-Peng Li, Hai-Yan Zhang, Xiao-Dong Xu, Ming-Yang, Tie-Jun Li, Shu-Tian Song

“…Inflammation plays a major role in the development of myocardial ischemia-reperfusion (IR) injury. …”
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Clinical, cytologic, bacteriologic and radiographic analysis of respiratory diseases in dogs by Mehmet Maden, Fatih M. Birdane, Fahrettin Atkan, Hasan H, Hadimli

“…The importance of bronchoalveolar lavage (BAL) (Kid and culture were analysed and it is considered to be important to detect the ethiologic factor and overall rate of inflammation. In addition to this, radiography were also evaluated if there was any contribution to the diagnosis. …”
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Role of T Regulatory Cells and Myeloid-Derived Suppressor Cells in COVID-19 by Alhasan Alsalman, Mohammad A. Al-Mterin, Eyad Elkord

“…On the other side, during late stages, Tregs reduce inflammation-induced organ damage. Therefore, inhibition of Tregs in early stages and their expansion in late stages have potentials to improve clinical outcomes. …”
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Cystic Form of Duodenal Dystrophy (Clinical Case) by D. E. Okonskaya, Kh. H. Ayvazyan, Yu. A. Stepanova, A. V. Zhao, E. A. Sokolova

“…The report is devoted to the description of a case of successful treatment of a cystic form of duodenal dystrophy — a chronic inflammation of the pancreatic tissue, ectopic in the wall of the duodenum. …”
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RHINITIS: A SHORT REVIEW by Felix Daniel Lucaci, Sorin Marian Mârza, Radu Lăcătuș, Robert Cristian Purdoiu

“…Rhinitis, defined as inflammation of the nasal mucosa, is a prevalent and multifactorial condition affecting companion animals, particularly dogs and cats. …”
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Navigating the complex role of senescence in liver disease by Qiuting Li, Lin Wang, Yuanyuan Ji

“…The objective of this review is to offer a contemporary overview of the pathophysiological events involving hepatic senescent cells and to elucidate their role in the onset and progression of liver diseases, particularly through mechanisms like telomere shortening, genomic and mitochondrial DNA damage, and inflammation. Additionally, this review discusses the emerging senolytic therapies aimed at targeting senescent cells to delay or mitigate liver disease progression. …”
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Hubungan Nilai Laju Endap Darah (LED) dengan Kadar C-Reactive Protein (C-RP) pada Pasien Positif Covid-19 by Yumna Tahani Tsamarah, I Gusti Ayu Nyoman Danuyanti, Siti Zaetun

“…Some indicators of inflammation markers include Erythrocyte Sedimentation Rate (ESR) and C-Reactive Protein (CRP). …”
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The systemic evolutionary theory of the origin of cancer (SETOC): an update by Antonio Mazzocca, Giovanni Ferraro, Giovanni Misciagna

“…The SETOC proposes that malignant transformation occurs when cells undergo a continuous adaptation process in response to long-term injuries, leading to tissue remodeling, chronic inflammation, fibrosis, and ultimately cancer. This process involves a maladaptive response, wherein the 'endosymbiotic contract’ between the nuclear-cytoplasmic system (derived from the primordial archaeal cell) and the mitochondrial system (derived from the primordial α-proteobacterium) gradually breaks down. …”
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Key Role of Phosphorylation in Small Heat Shock Protein Regulation via Oligomeric Disaggregation and Functional Activation by Zachary B. Sluzala, Angelina Hamati, Patrice E. Fort

“…This disaggregation mechanism is crucial for protecting cells from stress-induced damage, including apoptosis, inflammation, and other forms of cellular dysfunction. …”
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Esophageal Plasmacytoma Diagnosed in a Patient Presenting with Cardiac Symptoms: A Novel Case by Cheryl Rimmer, Anup Hazra, Vito M. Gulli, Richard Siderits, Mark Castaldi, Zafar Zamir

“…Histopathological examination revealed marked acute and chronic inflammation, granulation tissue, and overlying necroinflammatory exudate. …”
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An Unusual Cause of Abdominal Pain: Three Lead Pellets within the Appendix Vermiformis by Orhan Veli Ozkan, Vecdi Muderris, Fatih Altintoprak, Orhan Yagmurkaya, Omer Yalkin, Fehmi Celebi

“…Pathologically, three lead pellets were embedded in the appendix, which showed signs of intramucosal inflammation. Foreign bodies causing appendicitis are rare. …”
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Curcumin delivery nanoparticles based on Maillard reaction of Haematococcus pluvialis protein/galactose for alleviating acute alcoholic liver damage by Xinyi Liu, Yukun Song, Shasha Cheng, Mingqian Tan

“…In addition, the HPPGAL-CUR delivery system possessed liver targeting property due to the existence of GAL, which could effectively alleviate the alcohol-induced liver damage and the inflammation indexes by inhibiting the oxidative stress. …”
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Deciphering the Immune Subtypes and Signature Genes: A Novel Approach Towards Diagnosing and Prognosticating Severe Asthma Through Interpretable Machine Learning by Yue Hu, Yating Lin, Bo Peng, Chunyan Xiang, Wei Tang

“…Characterized by chronic inflammation of the bronchial passages, its symptoms include cough, wheezing, dyspnea, and chest tightness. …”
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