-
6021
<i>Pneumocystis</i> Pneumonia Severity Is Associated with Taxonomic Shifts in the Respiratory Microbiota
Published 2025-01-01“…Recent evidence suggests that the microbiota of the respiratory tract may play a role in stimulating or repressing pulmonary inflammation, as well as the progression of both bacterial and viral pneumonia. …”
Get full text
Article -
6022
The functional insight into the genetics of cardiovascular disease: results from the post-GWAS study
Published 2022-03-01“…A significant impact on binding sites of thirteen TFs including those involved in blood cells formation, hematopoiesis, macrophage function, inflammation, and vasoconstriction was found in K562 cells. 21 rSNP gene targets and 5 partners predicted by PPI were enriched for spliceosome and endocytosis KEGG pathways, endosome sorting complex and mRNA splicing REACTOME pathways. …”
Get full text
Article -
6023
Correlation of serum C - reactive protein with clinical parameters in diabetic patients having chronic periodontitis before and after treatment
Published 2020-06-01“… Background and Objectives: Chronic periodontitis is an infectious disease characterized by inflammation within the supporting tissues of the teeth, progressive attachment loss, and bone loss. …”
Get full text
Article -
6024
A Rare Case of Colonic Sarcoidosis Presenting as a Mass
Published 2020-01-01“…Pathology of the colon and peritoneal biopsy was significant for the presence of noncaseating granulomas and confluent granulomatous inflammation. The patient was diagnosed with colonic sarcoidosis, and treatment with corticosteroids was initiated. …”
Get full text
Article -
6025
Light-chain proximal tubulopathy: a retrospective study from a single Chinese nephrology referral center
Published 2024-12-01“…Proximal tubulopathy with cytoplasmic inclusions accounted for the majority (53%), followed by tubulopathy associated with interstitial inflammation reaction (26%), proximal tubulopathy without cytoplasmic inclusions (16%), and proximal tubulopathy with lysosomal indigestion/constipation (5%). …”
Get full text
Article -
6026
Comprehensive Analysis of Transcriptome Sequencing Data in the Lung Tissues of COPD Subjects
Published 2015-01-01“…Chronic obstructive pulmonary disease (COPD) is a complex disease characterized by airflow limitation. Although airway inflammation and oxidative stress are known to be important in the pathogenesis of COPD, the mechanism underlying airflow obstruction is not fully understood. …”
Get full text
Article -
6027
Role of interleukin-4 receptor α polymorphism in patients with asthma and its correlation with asthma severity
Published 2025-01-01“… Asthma is a heterogeneous disease characterized by chronic airway inflammation. It is defined by the history of respiratory symptoms such as wheeze, shortness of breath, chest tightness, and cough that vary over time and intensity, together with variable expiratory airflow limitation. …”
Get full text
Article -
6028
The pro-inflammatory cytokine Tumor Necrosis Factor alpha (TNF-α) in Diabetic Nephropathy
Published 2024-07-01“…There is now proof that inflammation and activated innate immunity play important roles in the etiology of problems with diabetes. …”
Get full text
Article -
6029
Suppression of Migration and Invasion by 4-Carbomethoxyl-10-Epigyrosanoldie E from the Cultured Soft Coral Sinularia sandensis through the MAPKs Pathway on Oral Cancer Cells
Published 2024-01-01“…The compound 4-carbomethoxyl-10-epigyrosanoldie E, derived from the Sinularia sandensis soft coral species grown in cultures, exhibits properties that counteract inflammation. Moreover, it has been observed to trigger both apoptosis and autophagy within cancerous cells. …”
Get full text
Article -
6030
Systematic Study of the Immune Components after Ischemic Stroke Using CyTOF Techniques
Published 2020-01-01“…Our data showed (1) dynamic changes in the immune cell numbers in the ischemic brain and peripheral organs. (2) The expression levels of cell surface markers indicate the inflammation response status after stroke. Interestingly, CD62L, a key adhesion molecule, regulates the migration of leukocytes from blood vessels into secondary lymphoid tissues and peripheral tissues. (3) A strong leukocyte network across the brain and peripheral immune organs was identified using the R program at day 1 after ischemia, suggesting that the peripheral immune cells dramatically migrated into the ischemic areas after stroke. …”
Get full text
Article -
6031
Plasma brain-related biomarkers and potential therapeutic targets in pediatric ECMO
Published 2025-01-01“…Its potential life-saving benefits are tempered by the significant risk for acute brain injury (ABI), from both primary pathophysiologic factors and ECMO-related complications through central nervous system cellular injury, blood-brain barrier dysfunction (BBB), systemic inflammation and neuroinflammation, and coagulopathy. …”
Get full text
Article -
6032
Identification of Bacterial Lipopolysaccharide-Associated Genes and Molecular Subtypes in Autism Spectrum Disorder
Published 2025-01-01“…We delineated two distinct molecular subtypes (Cluster 1 and Cluster 2), with GSVA indicating that Cluster 2 showed upregulation of immune- and inflammation-related pathways. This cluster exhibited increased levels of antimicrobial agents, chemokines, cytokines, and TNF family cytokines, alongside activation of bacterial lipoprotein-related pathways. …”
Get full text
Article -
6033
An Unusual Case of Systemic Inflammatory Myofibroblastic Tumor with Successful Treatment with ALK-Inhibitor
Published 2014-01-01“…A biopsy of the liver showed portal tract expansion by a spindle cell proliferation rich in inflammation. Tumor cells showed immunoreactivity for smooth muscle actin and anaplastic lymphoma kinase 1 (ALK1). …”
Get full text
Article -
6034
Combination of Fractional Exhaled Nitric Oxide (FeNO) Level and Asthma Control Test (ACT) in Detecting GINA-Defined Asthma Control in Treated Asthmatic Patients in Vietnam
Published 2020-01-01“…FeNO has been used as a marker for Th2-mediated airway inflammation in asthma. There is evidence which recommends the use of this biomarker in asthma management. …”
Get full text
Article -
6035
Effect of weight loss on the course of non-alcoholic fatty liver disease: results of 6-month follow-up
Published 2015-03-01“…Weight loss for at least 5% was gained in 44,1% of patients with NAFLD in association to obesityand in 56,6% of those with NAFLD in combination to MS, that was accompanied by significant reduction of lipid atherogenic fraction levels (cholesterol, low density lipoproteins), decrease of insulin resistance index, CRP and TNF-α inflammation markers, and decrease of leptin concentration in MS group. …”
Get full text
Article -
6036
Cathepsin C Is Involved in Macrophage M1 Polarization via p38/MAPK Pathway in Sudden Cardiac Death
Published 2021-01-01“…This included a total of 265 differential proteins which were involved in SCD-related processes, such as inflammation, muscle system process regulation, metal ion transport, and lysosomal pathway. …”
Get full text
Article -
6037
Estimation of D-dimer, C-reactive protein and ferritin in Covid-19 survivors in a North Indian Hospital, Lucknow, India.
Published 2024-08-01“…COVID-19 survivors who are critically ill featured hyper inflammation and the associated biomarkers may be useful for risk stratification. …”
Get full text
Article -
6038
Lactiplantibacillus plantarum 22 A-3 ameliorates leaky gut in mice through its anti-inflammatory effects
Published 2025-01-01“…Abstract There are limited studies on the improvement of leaky gut with minor inflammation associated with various diseases. To explore the therapeutic potential of Lactiplantibacillus plantarum 22 A-3, a member of the Lactobacillus species, in addressing a leaky gut. …”
Get full text
Article -
6039
Selected Abstracts of the 8th World Summit on Pediatrics; Madrid (Spain); October 3-6, 2024
Published 2025-01-01“…FROM ADVERSE CHILDHOOD EXPERIENCES TO INFLAMMATION: EXPLORING ITS ASSOCIATION IN MEXICAN CHILDREN • A.J. del Rio, I. …”
Get full text
Article -
6040
Association between neutrophil-albumin ratio and ultrasound-defined metabolic dysfunction-associated fatty liver disease in U.S. adults: evidence from NHANES 2017–2018
Published 2025-01-01“…Abstract Background Metabolic dysfunction-associated fatty liver disease (MAFLD) is increasingly prevalent, and systemic inflammation markers may play a role in its pathogenesis. …”
Get full text
Article