A mutation in LXRα uncovers a role for cholesterol sensing in limiting metabolic dysfunction-associated steatohepatitis by Alexis T. Clark, Lillian Russo-Savage, Luke A. Ashton, Niki Haghshenas, Nicolas A. Amselle, Ira G. Schulman

“…When fed a high fat, high cholesterol diet LXRα mutant mice rapidly develop pathologies associated with Metabolic Dysfunction-Associated Steatohepatitis (MASH) including ballooning hepatocytes, liver inflammation, and fibrosis. Strikingly LXRα mutant mice have decreased liver triglycerides but increased liver cholesterol. …”
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Combined treatment of an infected paraurethral cyst by A. A. Kostin, L. V. Shaplygin, N. G. Kulchenkо, A. Mansur

“…Persistent microflora contributes to the aggravation of symptoms, up to the formation of an abscess. With inflammation of the paraurethral cyst, there is still no clear treatment algorithm. …”
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Qualitative and Quantitative Evaluation of Chemical Constituents from Shuanghuanglian Injection Using Nuclear Magnetic Resonance Spectroscopy by Ziyan Wang, Zuoyuan Wang, Miaomiao Jiang, Jing Yang, Qingfen Meng, Jianli Guan, Maoling Xu, Xin Chai

“…Guided by the approach of network pharmacology, the potential activities were briefly predicted for seven primary metabolites except for formic acid, such as anti-inflammation, antioxidation, and cardiovascular protection. …”
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Whipple’s Disease-Associated Pulmonary Hypertension with Positive Vasodilator Response Despite Severe Hemodynamic Derangements by Salah Najm, Joud Hajjar, Robert P Nelson, Ramana S Moorthy, Karen M Wolf, Tim Lahm

“…Furthermore, the case highlights the phenomenon of PH in the setting of inflammation, suggesting that adequate control of the inflammatory response can be accompanied by a marked improvement in hemodynamics in certain types of PH.…”
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The effect of regular exercise and vitamin C on hs-cTnT TNF-α levels in obese boys students by Mohammadbagher Forghani Ozrudı, Javad Alızade, Aliakbar Raıespour

“…Therefore the use of non-pharmacological methods, exercise, vitamin C and combination of the above interventions may lead to a reduction of inflammation in obese boy’s students.…”
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Relationship between Fractional Exhaled Nitric Oxide and Forced Oscillometric Technique in the Assessment of Asthma by Amjed H. Abbas, Ahmed Hussein Jasim, Kareem Nasir Hussien Alesawi, Samir Sawadi Hammoud

“…Background: Fractional exhaled nitric oxide (FeNO) and forced oscillometric technique (FOT) represent noninvasive and sensitive tools for measuring airway inflammation and resistance, respectively, but the studies that use FeNO and FOT to assess patients with asthma until now are few. …”
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Rethinking risk prediction: The role of albumin and other parameters in implant-associated complications after hip or knee arthroplasty. by Petr Domecky, Anna Rejman Patkova, Lenka Zaloudkova, Tomas Kucera, Pavel Sponer, Josef Maly

“…<h4>Background</h4>Total hip (THA) or knee (TKA) arthroplasty is still a traumatic and challenging operation that induces inflammation, with a particularly high risk of acute-phase reaction. …”
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Bile Reflux Gastritis: Insights into Pathogenesis, Relevant Factors, Carcinomatous Risk, Diagnosis, and Management by Xiaolan Shi, Zijiao Chen, Yi Yang, Su Yan

“…Bile reflux gastritis (BRG), a kind of gastrointestinal disorder in clinical practice, is characterized by regurgitation and inflammation. However, lack of guidelines leads to simple cognition and even ignorance of this disease for clinicians. …”
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Knockdown of decorin in human bone marrow mesenchymal stem cells suppresses proteoglycan layer formation and establishes a pro-inflammatory environment on titanium oxide surfaces by Hisanobu Kamio, Kazuto Okabe, Masaki Honda, Kensuke Kuroda, Shuhei Tsuchiya

“…These results suggest that endogenous DCN plays a crucial role in PG layer formation and that the PG layer alters inflammation around Ti materials. Graphical Abstract…”
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Management of Exercise-Induced Bronchoconstriction by Mark D Inman

“…Evidence suggests that exercise and the ensuing bronchoconstriction do not contribute to a worsening of asthmatic inflammation. Asthmatics should not be discouraged from exercising, and, with adequate management, most patients should be able to exercise regularly with only minor symptoms. …”
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Analysis of Total Flavonoid and Antioxidant Activity of Black Turmeric (Curcuma caesia) using ABTS (2,2-azinobis-3-Ethylbenzothiazoline-6-Sulfonic Acid) Method by Molesy Fransina Tanesib, Kholif Sholehah Indra Kurniasih, Arde Toga Nugraha

“…Experts believe that black turmeric could have some amazing health benefits, such as protecting against oxidative stress and reducing inflammation. Black turmeric was extracted using the maceration method with a methanol solvent. …”
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Investigation of Functional Activity of Cells in Granulomatous Inflammatory Lesions from Mice with Latent Tuberculous Infection in the New Ex Vivo Model by Elena Ufimtseva

“…Detected modulation in dynamics of production of pro-inflammatory cytokines, growth factors, and leukocyte surface markers by granuloma cells has indicated continued processes of activation and deactivation of granuloma inflammation cells during the latent tuberculous infection progress in mice.…”
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Exploring novel pharmacological trends: Natural compounds in dry eye disease management by Rák Tibor, Csutak Adrienne

“…Dry eye disease (DED) is an ocular condition characterized by altered tear film homeostasis, resulting in symptoms like tear film instability, hyperosmolarity, inflammation, and neurosensory abnormalities. It affects visual acuity and quality of life and is influenced by age, gender, and environmental factors. …”
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Promoting Articular Cartilage Regeneration through Microenvironmental Regulation by Kai Liu, Bingjun Zhang, Xiaoling Zhang

“…These approaches only relieve pain and reduce inflammation; however, they have significant side effects and high costs. …”
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Novel CT Features of an Abdominal Gossypiboma in a Female Dog by Mylene Auger, Shelly Olin, Federica Morandi

“…Surgical recovery was uneventful and a follow-up CT after 3 months was consistent with resolving granulomatous inflammation and fibrosis. Clinical Relevance. The presence of multiple peripherally enhancing tracts extending from the abdominal mass through the hypaxial musculature is a CT feature which has not yet been described in the veterinary literature. …”
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Microbial boundaries in peri-implantitis: a review of pathogen-related advances by Ehab Qasim Talib, Ghada Ibrahim Taha, Dhuha Mahmood Ali, Sahar Hashim Al-Hindawi, Fadia Abd Almuhsin Al-Khayat, Israa Amer Hasan

“…Similar to periodontal disease, this kind of pathological condition is characterized by inflammation of the tissues surrounding dental implants or fillings. …”
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Overview of Platelet Physiology: Its Hemostatic and Nonhemostatic Role in Disease Pathogenesis by Kakali Ghoshal, Maitree Bhattacharyya

“…Platelets are also involved in the fundamental biological process of chronic inflammation associated with disease pathology. Platelet indices like mean platelets volume (MPV), platelets distributed width (PDW), and platelet crit (PCT) are useful as cheap noninvasive biomarkers for assessing the diseased states. …”
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Sarcoid-Like Mediastinal Lymphadenopathy in Gynecologic Malignancy by Bilal H. Lashari, Megumi Asai, Gissele Randleman, Martha Sack, Rajeshkumar Patel

“…We performed a search of our institutional database for all EBUS-TBNA biopsies conducted within the past five years that revealed granulomatous inflammation. All adult female patients with a history of gynecologic malignancy were included. …”
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Case Report: Atypical post-COVID Cogan's syndrome [version 2; peer review: 2 approved] by Sayhi Sameh, Chaima Zitouni, Mayssa Bouzidi, Wafa Sleimi, Sameh Mezri

“…Background Cogan’s syndrome is a rare autoimmune disorder characterized by ocular inflammation, vestibulocochlear dysfunction, and systemic vasculitis. …”
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The Role of Limbal Epithelial Stem Cells in Regulating Corneal (Lymph)angiogenic Privilege and the Micromilieu of the Limbal Niche following UV Exposure by M. Notara, A. Lentzsch, M. Coroneo, C. Cursiefen

“…Defects in limbal epithelial stem cells are linked to corneal neovascularisation, including lymphangiogenesis, chronic inflammation, conjunctivalisation, epithelial abnormalities including the presence of goblet cells, breaks in Bowman’s membrane, persistent epithelial defects and ulceration, ocular surface squamous neoplasia, lipid keratopathy, pain, discomfort, and compromised vision. …”
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