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5881
Nutritional and Pharmacological Effects on Oxidative Stress in Soft Tissue and Bone Remodeling
Published 2018-01-01“…We provide a review of the current literature of how oxidative damage and inflammation are linked to bone damage, Charcot neuroarthropathy, delayed wound healing, diabetic complications, and delayed flap consolidation. …”
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5882
Targeting the B-Cell Pathway in Lupus Nephritis: Current Evidence and Future Perspectives
Published 2013-01-01“…Several hypotheses are currently experimentally tested to further elucidate the direct induction of inflammation through interaction of the pathological autoantibodies with intrinsic glomerular components and the triggering of a complement-driven autoinflammatory cascade. …”
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5883
Helicobacter pylori-Induced Chronic Gastritis and Assessing Risks for Gastric Cancer
Published 2013-01-01“…Chronic gastritis is an inflammation of the gastric mucosa and has multiple etiologies. …”
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5884
Potential therapeutic effect of thymoquinone on cisplatin-induced hepatotoxicity in rats
Published 2024-03-01“…<p> <b>Results: </b>CIS application increased liver enzyme levels, histopathological changes, inflammation, oxidative stress and apoptosis in liver tissue and caused a decrease in OTULIN level. …”
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5885
ANCA-Associated Vasculitides and Hematologic Malignancies: Lessons from the Past and Future Perspectives
Published 2019-01-01“…Furthermore, the pathogenesis of ANCA-associated vasculitis has been reviewed with particular emphasis on the role of proteinase 3 (PR3) in fuelling granulomatosis with polyangiitis (GPA) inflammation. PR3 is a bactericidal protein expressed by neutrophilic granules and on their plasma membrane. …”
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5886
GSK-3𝜷: A Bifunctional Role in Cell Death Pathways
Published 2012-01-01“…Secondary to the role of GSK-3β in various diseases including Alzheimer’s disease, inflammation, diabetes, and cancer, small molecule inhibitors of GSK-3β are gaining significant attention. …”
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5887
Potential Role of the Inflammasome-Derived Inflammatory Cytokines in Pulmonary Fibrosis
Published 2011-01-01“…However, recent progress in inflammasome research has greatly contributed to our understanding of its role in inflammation and fibrosis development. The inflammasome is a multiprotein complex that is an important component of both the innate and adaptive immune systems. …”
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5888
The Role of the Immune System in Huntington’s Disease
Published 2013-01-01“…Further understanding the influence of inflammation in HD using mouse models may open various avenues for promising therapeutic approaches aiming at slowing disease progression or forestalling onset of disease.…”
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5889
Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options
Published 2014-09-01“…In the last years more and more data appear on changes in qualitative and quantitative spectrum of intestinal microflora in combination to low degree inflammation of colonic mucosa at IBS that allowed to reconsider standard concepts on pathogenesis of this functional disorder. …”
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5890
Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders?
Published 2012-01-01“…., lipopolysaccharide) resulting in inflammation and (2) bacterial metabolites of dietary compounds (e.g., SCFA from fiber), which have biological activities that regulate host functions. …”
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5891
Sterile osteomyelitis: a cardinal sign of autoinflammation
Published 2024-12-01“…Autoinflammatory bone disorders (ABDs) are characterized by sterile bone inflammation stemming from dysregulated innate immune responses. …”
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5892
Janus kinase inhibitors and biologics for treatment of livedoid vasculopathy: a systematic review
Published 2025-12-01“…Purpose: Livedoid vasculopathy (LV) is a chronic microvascular thrombosis disorder with an unclear pathogenesis, potentially involving hypercoagulability and inflammation. This systematic review aims to evaluate the efficacy and safety of Janus kinase (JAK) inhibitors and biologics in the treatment of LV.Materials and methods: A comprehensive search was conducted in PubMed, EMBASE, and the Cochrane Library on June 10, 2024, to identify relevant studies evaluating the use of JAK inhibitors and biologics in LV treatment.Results: A total of 15 articles were included in the review. …”
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5893
Hsp70 and Its Molecular Role in Nervous System Diseases
Published 2011-01-01“…Hsp70 functions as a chaperone and protects neurons from protein aggregation and toxicity (Parkinson disease, Alzheimer disease, polyglutamine diseases, and amyotrophic lateral sclerosis), protects cells from apoptosis (Parkinson disease), is a stress marker (temporal lobe epilepsy), protects cells from inflammation (cerebral ischemic injury), has an adjuvant role in antigen presentation and is involved in the immune response in autoimmune disease (multiple sclerosis). …”
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5894
Lupus Enteritis as an Initial Presentation of Systemic Lupus Erythematosus
Published 2014-01-01“…Lupus enteritis is a distinct subset of SLE, defined as either vasculitis or inflammation of the small bowel, with supportive image and/or biopsy findings. …”
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5895
Chronic active lesions in multiple sclerosis: classification, terminology, and clinical significance
Published 2024-12-01“…In multiple sclerosis (MS), increasing disability is considered to occur due to persistent, chronic inflammation trapped within the central nervous system (CNS). …”
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5896
Retropharyngeal Calcific Tendinitis Mimicking a Retropharyngeal Phlegmon
Published 2013-01-01“…It was first described by Hartley in 1964 as an inflammation of the longus colli muscle secondary to calcium crystals deposition on its insertion. …”
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5897
Primary Pneumatosis Intestinalis of Small Bowel: A Case of a Rare Disease
Published 2014-01-01“…The present report describes the case of an 86-year-old man with symptomatic primary PI of small bowel treated with surgical approach after periodic episodes of cysts rupture and superimposed inflammation revealed on the basis of a clinical suspicion thanks to abdominal computed tomography. …”
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5898
Comparative Evaluation of Salivary Ferritin Levels as a Predictor Inflammatory Biomarker Before and After Non Surgical Periodontal Therapy- An Interventional Study
Published 2024-12-01“…Background: Ferritin plays a crucial role in the host immune response, with elevated serum ferritin levels established in various chronic inflammation-related diseases, including periodontitis. …”
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5899
The influence of occupational heat stress on serum inflammatory cytokines among traditional bakery workers in Iran.
Published 2024-01-01“…As a result of years of working in high-temperature conditions, inflammation can lead to subsequent diseases in workers. …”
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5900
An Update on the Potential of Mesenchymal Stem Cell Therapy for Cutaneous Diseases
Published 2021-01-01“…Numerous clinical and preclinical studies have demonstrated the potential application of MSCs in the treatment of tissue inflammation and immune diseases, including inflammatory skin diseases. …”
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