-
5881
Investigating Metabolic Phenotypes for Sarcoidosis Diagnosis and Exploring Immunometabolic Profiles to Unravel Disease Mechanisms
Published 2024-12-01“…<b>Conclusions:</b> we explored immunometabolic phenotypes by comparing patients with sarcoidosis with patients with COVID-19 and healthy controls, revealing potential metabolic pathways associated with acute and chronic inflammation across the stages of sarcoidosis.…”
Get full text
Article -
5882
Impact of Endurance Exercise Training on Biomarkers of Aortic Endothelial Damage in Diabetic Rats
Published 2024-01-01“…The aim is to elucidate the impact of different exercises (interval and continuous training) and metformin on biochemical parameters, aortic injury, oxidative stress, and inflammation to provide insights into potential therapeutic interventions for diabetes-associated vascular complications. …”
Get full text
Article -
5883
Chronic C-Type Natriuretic Peptide Infusion Attenuates Angiotensin II-Induced Myocardial Superoxide Production and Cardiac Remodeling
Published 2012-01-01“…Myocardial oxidative stress and inflammation are key mechanisms in cardiovascular remodeling. …”
Get full text
Article -
5884
Phenolic-Rich Baccaurea angulata Modulates Inflammatory Biomarkers of Atherosclerosis
Published 2018-01-01“…Atherosclerosis is the most common cause of CVD. Inflammation has been progressively acknowledged as a vital and central player in the pathophysiology of atherosclerosis. …”
Get full text
Article -
5885
Biocompatibility of new cement based capping material prepared from eggshell and biopolymer (chitosan).
Published 2022-07-01“…Results: The histological preparation in control group at 7 days time period demonstrated simple inflammatory reaction represented by slight looseness of the collagen fibers with increase the extracellular spaces between the fibers indicating mild edematous inflammation. For the Experimental group, MTA and Biodentine group there was great similarity in the tissue reaction when comparedwith control group. …”
Get full text
Article -
5886
CircTRRAP Knockdown Has Cardioprotective Function in Cardiomyocytes via the Signal Regulation of miR-370-3p/PAWR Axis
Published 2022-01-01“…Downregulation of circTRRAP promoted cell growth but inhibited apoptosis, inflammation, and oxidative stress in hypoxic cells. …”
Get full text
Article -
5887
Mesenchymal Stem Cell-Based Therapy of Inflammatory Lung Diseases: Current Understanding and Future Perspectives
Published 2019-01-01“…Accordingly, new therapeutic agents that will attenuate ongoing inflammation and, at the same time, promote regeneration of injured alveolar epithelial cells are urgently needed. …”
Get full text
Article -
5888
The Role of Neuroglia in the Development and Progression of Schizophrenia
Published 2024-12-01“…In the present paper, we review the interactions of brain microglia, astrocytes and oligodendroglia with aspects such as transmitter dysregulation, neuro-inflammation, oxidative stress, synaptic function, the gut microbiome, myelination and the blood–brain barrier that appear to affect the cause, development and treatment of schizophrenia. …”
Get full text
Article -
5889
Exploring the mechanism of Schisandra rubriflora in the treatment of polycystic ovary syndrome based on network pharmacology and molecular docking
Published 2025-01-01“…Schisandrin could attenuate lipopolysaccharide-induced inflammation, oxidative stress, and apoptosis of KGN cells and rat ovarian granulosa cells, as well as inhibit hub target expression and TNF pathway activation. …”
Get full text
Article -
5890
Diagnostic Algorithm for Joint Pain in Patients with Inflammatory Bowel Disorders
Published 2022-01-01“…IBD-associated arthritis was diagnosed in 41 (42.3%) cases, osteoarthritis — in 38 (39.2%) IBD patients with joint pain, arthralgia with no objective inflammation, impaired joint function or lesions in X-ray and/or ultrasound — in 13 (13.4%) patients.Conclusion. …”
Get full text
Article -
5891
Endometrial Regenerative Cell-Derived Conditioned Medium Alleviates Experimental Colitis
Published 2022-01-01“…Endometrial regenerative cells (ERCs) have been shown to exert immunosuppressive effects in different models of inflammation, and stem cell-derived conditioned media (CM) have advantages over cell therapy in terms of easy access and direct action. …”
Get full text
Article -
5892
MicroRNA155 in non-small cell lung cancer: a potential therapeutic target
Published 2025-02-01“…MicroRNAs (miRNAs), a large family of non-coding RNAs, play crucial roles in regulating several key biological processes, including cell proliferation, differentiation, inflammation, and apoptosis. Among these, microRNA155(miR-155) is one of the most conserved and versatile miRNAs, predominantly overexpressed in various diseases, including malignant tumors. …”
Get full text
Article -
5893
Mesenchymal Stromal Cell Therapy in Ischemia/Reperfusion Injury
Published 2015-01-01“…Furthermore, the reperfusion of ischemic tissues induces both local and systemic inflammation. In the particular field of SOT, IRI is an unavoidable event, which conditions both short- and long-term outcomes of graft function and survival. …”
Get full text
Article -
5894
Gut microbiota-derived metabolites and chronic inflammatory diseases
Published 2025-01-01“…Dysbiosis disrupts the production and function of these metabolites, thereby contributing to immune dysregulation, chronic inflammation, and disease progression. This review examines the role of gut microbiota-derived metabolites in chronic inflammatory diseases, with a focus on their immunomodulatory and metabolic effects. …”
Get full text
Article -
5895
Etiopathogenic theories of nervous system diseases in Vilnius in the early 19th century: “insanity and epilepsy exacerbate when the moonlight shines”
Published 2023-10-01“…“Inflammatory agents” were reported to cause traumatic tetanus as inflammation spread upwards from the nerve endings, tendons, and ligaments to the brain. …”
Get full text
Article -
5896
Heart Rate Variability: A Psychophysiological Factor Related to Both Regular Physical Activity and Eudaimonic Well‐Being Among Young Adults
Published 2025-01-01“…ABSTRACT Introduction Eudaimonic well‐being (EWB), which refers to optimal human functioning, is associated with psychophysiological outcomes, such as reduced inflammation and a lower risk of depression. Although physical activity (PA) and mindfulness have been shown to be predictive factors for EWB, potential mediators of the relationships of PA or mindfulness with EWB have yet to be identified. …”
Get full text
Article -
5897
Immune-Boosting and Antiviral Effects of Antioxidants in COVID-19 Pneumonia: A Therapeutic Perspective
Published 2025-01-01“…Clinical evidence suggests that antioxidant supplementation may improve patient outcomes by decreasing inflammation, supporting immune cell function, and potentially shortening recovery times. …”
Get full text
Article -
5898
Natural products based on Correa's cascade for the treatment of gastric cancer trilogy: Current status and future perspective
Published 2025-02-01“…In phase I, NPs modulate Helicobacter pylori urease activity, motility, adhesion, virulence factors, and drug resistance, thereby inhibiting H. pylori-induced gastric mucosal inflammation and oxidative stress, and facilitating ulcer healing. …”
Get full text
Article -
5899
Intrastromal autologous implantation of adipose derived adult stem cells for the management of established corneal scars
Published 2025-03-01“…Observations: ADASC were isolated by elective liposuction, and a solution composed of 3x106 ADASC contained in 1mL saline was used to soak a corneal intrastromal pocket created with femtosecond laser at mid-depth. No signs of inflammation or rejection were observed. One year after surgery, we observed a complete restoration of the pre-existing corneal stroma scars, observed both clinically and by anterior segment OCT. …”
Get full text
Article -
5900
Carbon Nanomaterials in the Treatment of Infectious Bone Defects and Wound Scars after Wushu Fractures
Published 2020-01-01“…Although modern antibiotics and surgical technology have made great progress, when using carbon nanomaterials to treat bone marrow-induced inflammation after martial arts fractures, how to simultaneously repair bone defects and control wound infections is the current focus of orthopedics research. …”
Get full text
Article