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5861
An atypical case of infective endocarditis initially diagnosed as myopericarditis
Published 2025-03-01“…Background: Acute myopericarditis is inflammation of the pericardium, or the membrane surrounding the heart, and the myocardium, or the muscular myocardial layer of the heart. …”
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5862
Promising Therapeutic Functions of Bone Marrow Mesenchymal Stem Cells Derived-Exosome in Asthma
Published 2022-01-01“…Points also hold that BMMSC-Exo could interfere with airway inflammation and airway remolding in asthma via modulating the immune response, regulating gene expression, adjusting the phenotype of macrophage, etc. …”
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5863
Neutropenic Sepsis in the ICU: Outcome Predictors in a Two-Phase Model and Microbiology Findings
Published 2016-01-01“…Infections with coagulase-negative staphylococci and enterococci were associated with a significantly higher mortality and a high degree of systemic inflammation. Conclusion. Patients with persistent organ dysfunction show an increased mortality in the further course of their ICU stay. …”
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5864
The Fatty Acid Profile in Patients with Newly Diagnosed Diabetes: Why It Could Be Unsuspected
Published 2017-01-01“…Several studies have shown a link between proinflammatory activity and the presence or deficit of some fatty acids. Inflammation is associated with several diseases including diabetes. …”
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5865
Explore the Mechanism of Astragalus mongholicus Bunge against Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Experimental Verification
Published 2022-01-01“…Our results indicated that quercetin, as the main active component in AMB, exerts an anti-NAFLD effect by regulating the AMPK/MAPK/TNF-α and AMPK/ACC/CPT1α signaling pathways to inhibit inflammation and alleviate lipid accumulation.…”
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5866
Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway
Published 2017-01-01“…Subsequently, ANGPTL4 has been shown to be involved in several nonmetabolic and metabolic conditions, both physiological and pathological, including angiogenesis and vascular permeability, cell differentiation, tumorigenesis, glucose homoeostasis, lipid metabolism, energy homeostasis, wound healing, inflammation, and redox regulation. The transcriptional regulation of ANGPTL4 can be modulated by several transcription factors, including PPARα, PPARβ/δ, PPARγ, and HIF-1α, and nutritional and hormonal conditions. …”
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5867
BMP6, a potential biomarker of inflammatory fibrosis and promising protective factor for dilated cardiomyopathy
Published 2025-01-01“…Abstract Background Dilated cardiomyopathy (DCM) stands as one of the most prevalent and severe causes of heart failure. Inflammation plays a pivotal role throughout the progression of DCM to heart failure, while age acts as a natural predisposing factor for all cardiovascular diseases. …”
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5868
Insights into the binding selectivity of harzianoic acids A and B to tetraspanin CD81
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5869
Cavernous Hemangioma-Like Kaposi Sarcoma: Histomorphologic Features and Differential Diagnosis
Published 2013-01-01“…Typical histological findings of early-stage KS, consisting of mononuclear inflammation, extravasated erythrocytes, and a few immature vascular structures in superficial dermis, were observed. …”
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5870
Anti-Inflammatory therapeutic potential of Bungur (Lagerstroemia speciosa L.) leaves ethanolic extract against LPS-activated macrophage through TLR4/MD2 signaling: A computational...
Published 2025-01-01“…Excessive inflammation, driven by macrophage activation and nitric oxide (NO) production, underlies various diseases. …”
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5871
Adhesive polyelectrolyte coating through UV-triggered polymerization on PLGA particles for enhanced drug delivery to inflammatory intestinal mucosa
Published 2025-01-01“…Abstract Administering medication precisely to the inflamed intestinal sites to treat ulcerative colitis (UC), with minimized side effects, is of urgent need. In UC, the inflammation damaged mucosa contains a large number of amino groups which are positively charged, providing new opportunities for drug delivery system design. …”
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5872
Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases
Published 2012-01-01“…PPARγ ligands show great promise in moderating lung inflammation, as antiproliferative agents in combination to enhance standard chemotherapy in lung cancer and as treatments for pulmonary fibrosis, a progressive fatal disease with no effective therapy. …”
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5873
On the Dual Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) in Human Malignancies
Published 2018-01-01“…Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a glycoprotein belonging to the carcinoembryonic antigen (CEA) family that is expressed on a wide variety of cells and holds a complex role in inflammation through its alternate splicing and generation of various isoforms, mediating intricate mechanisms of modulation and dysregulation. …”
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5874
Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer’s disease
Published 2025-01-01“…Results We identified common disease endotypes, such as dedifferentiation, dysregulation of synaptic signaling, repression of mitochondrial function and metabolism, and inflammation. We ascertained the master transcriptional regulators associated with these endotypes, including REST, ASCL1, and ZIC family members (activation), and NRF1 (repression). …”
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5875
Unveiling Genital Tuberculosis: India’s hidden Infertility Epidemic
Published 2025-02-01“…Hematogenous spread of Mycobacterium tuberculosis leads to chronic inflammation, fibrosis, and scarring of reproductive organs, resulting in irreversible damage. …”
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5876
Association between exposure in the cement production industry and non-malignant respiratory effects: a systematic review
Published 2017-04-01“…A dose–response relationship between exposure and decline in lung function has only been shown in 1 cohort. 2 studies have detected small increases in FeNO levels during a work shift; 1 study reported signs of airway inflammation in induced sputum, whereas another did not detect an increase in hospitalisation rates.Conclusions Lack of power, adjustment for possible confounders and other methodological issues are limitations of many of the included studies. …”
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5877
Fetal Deaths in SARS-CoV-2-Infected Pregnant Women: A Portuguese Case Series
Published 2022-01-01“…Placental hypoperfusion and inflammation secondary to maternal immune response seem to play a role in the cascade of events that contribute to fetal death. …”
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5878
How does individualised physiotherapy work for people with low back pain? A Bayesian Network analysis using randomised controlled trial data.
Published 2021-01-01“…The current study cannot rule out that unmeasured mechanisms (such as tissue healing or reduced inflammation) may mediate the relationship between individualised physiotherapy treatment and improvement in disability. …”
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5879
Relationship between plasma uric acid levels, antioxidant capacity, and oxidative damage markers in overweight and obese adults: A cross-sectional study.
Published 2025-01-01“…Consequently, the presented evidence supports the potential antioxidant role of uric acid in the pathogenesis of obesity, contributing to our understanding of oxidative stress and inflammation that characterizes this illness.…”
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5880
Genistein Protects against Spinal Cord Injury in Mice by Inhibiting Neuroinflammation via TLR4-Mediated Microglial Polarization
Published 2022-01-01“…Apoptosis was determined by TUNEL staining, and inflammation was evaluated by measuring inflammatory factors by an ELISA kit. …”
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