Cutaneous Necrotizing Vasculitis and Leukopenia in a Cocaine User: Is Levamisole the Culprit? by Lara El Khoury, Nabil Zeineddine, Richard Felix, Mark Goldstein

“…Her skin biopsy showed fibroconnective tissue with signs of necrosis, acute and chronic inflammation, and thrombus formation. She was diagnosed with levamisole-induced vasculitis and successfully treated with withdrawal of cocaine use and local wound care.…”
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Migratory Polyarthritis Associated With Clopidogrel: A Case Report by Hamid Khederlou, Reza Hassanzadeh-Makoui, Vanoushe Azimi Pirsaraei

“…All symptoms and signs of joint inflammation had improved within five days of stopping the Clopidogrel. …”
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Adhesion of Neisseria meningitidis to dermal vessels leads to local vascular damage and purpura in a humanized mouse model. by Keira Melican, Paula Michea Veloso, Tiffany Martin, Patrick Bruneval, Guillaume Duménil

“…Bacterial mutants with altered type IV pili function also did not trigger inflammation or lead to vascular damage. This work demonstrates that local type IV pili mediated adhesion of N. meningitidis to the vascular wall, as opposed to circulating bacteria, determines vascular dysfunction in meningococcemia.…”
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Papillion-Lefèvre Syndrome: Periodontists’ Perspective by Sunil Kumar Biraggari, K. Krishna Mohana Reddy, J. Sudhakar, Shiva Shankar Bugude, Rajesh Nichenametla, Mazher Ahmed Hakeem, Swati Reddy Tiyyagura

“…Her intraoral examination revealed gingival inflammation, abscess formation, and periodontal pockets. …”
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PPARG Epigenetic Deregulation and Its Role in Colorectal Tumorigenesis by Lina Sabatino, Alessandra Fucci, Massimo Pancione, Vittorio Colantuoni

“…Peroxisome proliferator-activated receptor gamma (PPARγ) plays critical roles in lipid storage, glucose metabolism, energy homeostasis, adipocyte differentiation, inflammation, and cancer. Its function in colon carcinogenesis has largely been debated; accumulating evidence, however, supports a role as tumor suppressor through modulation of crucial pathways in cell differentiation, apoptosis, and metastatic dissemination. …”
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Factors Predetermining Increased Aqueous Humour Flare in Long-Term Glaucoma Treatment by G. Pakuliene, L. Kuzmiene, I. Januleviciene

“…Laser flare photometry is the noninvasive quantitative measurement of anterior chamber protein level and helps tracking intraocular inflammation. The purpose of our study was to evaluate the ocular aqueous humour flare in glaucoma patients, scheduled for cataract surgery without any other ocular diseases, and the association with pseudoexfoliation (PEX) syndrome, number of medications used, and BAK. …”
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Mechanics of cell sheets: plectin as an integrator of cytoskeletal networks by Zuzana Outla, Magdalena Prechova, Katerina Korelova, Jakub Gemperle, Martin Gregor

“…Subsequent loss of barrier function leads to disturbed tissue homeostasis and pathological consequences such as skin blistering or intestinal inflammation. In this article, we highlight the importance of the cytolinker protein plectin for the functional organization of epithelial cytoskeletal networks. …”
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Melittin, a Potential Natural Toxin of Crude Bee Venom: Probable Future Arsenal in the Treatment of Diabetes Mellitus by Md. Sakib Hossen, Siew Hua Gan, Md. Ibrahim Khalil

“…Other possible mechanisms may involve stimulation of phospholipase A2, increase of glucose uptake, improving lipid profile, and/or reduction of inflammation. This review summarizes the various sources, proteomics, biological roles, adverse effects, and medical applications of melittin and its mechanism of action in combating DM.…”
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Role of Nasal Endoscopy in Chronic Osteomyelitis of Maxilla and Zygoma: A Case Report by J. S. Arunkumar, Ashok S. Naik, K. C. Prasad, S. G. Santhosh

“…Cranial bones are infrequently involved, but spreading of inflammation with involvement of surrounding structures represents important risk, such as cerebral abscess, encephalitis, or meningitis. …”
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Correlation of blood coagulation parameters with comorbidities in COVID-19 patients: A retrospective study by Shuba N, Michael A

“…COVID-19 is a respiratory pathogenic strain with the potential to cause severe systemic inflammation and coagulopathy. Moreover, dysfunctional coagulation cascades in diabetes mellitus and an imbalance of cytokines in hypertension and cardiovascular diseases may pose an additional risk towards hypercoagulability and subsequent mortality amid those with COVID-19. …”
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Granulomatosis with Polyangiitis as a Cause of Sudden-Onset Bilateral Sensorineural Hearing Loss: Case Report and Recommendations for Initial Assessment by Paul R. Ratmeyer, Benjamin R. Johnson, Luis P. Roldan, Tania L. Kraai

“…GPA has also been associated with sensorineural hearing loss (SNHL), through inflammation of the cochlear apparatus. Early recognition, diagnostic laboratory evaluation, and appropriate treatment are essential to improve outcomes and achieve remission for patients with GPA. …”
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Vitamin D in Early Childhood and the Effect on Immunity to Mycobacterium tuberculosis by Anna Jane Battersby, Beate Kampmann, Sarah Burl

“…In contrast the role of vitamin D within the adaptive immune response appears to be more regulatory in function, perhaps as a mechanism to reduce unwanted inflammation. In this paper we focus on the effect of vitamin D on immunity to TB. …”
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Molecular and pathological identification of ovine pulmonary adenomatosis at Mosul city abattoirs by Osama Z. Jiad, Ahmed M. Al-Saidya

“…Ovine Pulmonary adenomatosis OPA is a frequent condition that affects small ruminants, characterized by inflammation of the lung parenchyma, and causes polyp-like hyperplasia of the epithelium lining the alveoli and interstitial tissue like bronchi. …”
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The management of bacterial conjunctivitis by Anna Kiełczewska, Aleksandra Kiełczewska, Grzegorz Szcześniak

“… Introduction and Purpose: Bacterial conjunctivitis, a common eye disease characterized by inflammation of the conjunctiva, poses a major challenge in clinical practice due to its prevalence, diverse etiology and the need for effective pharmacological treatment. …”
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A Cross-Study Biomarker Signature of Human Bronchial Epithelial Cells Infected with Respiratory Syncytial Virus by Luiz Gustavo Gardinassi

“…However, the evolution of statistical methods and functional analysis together with the large amount of expression data provide opportunities to uncover novel biomarkers of inflammation and infections. In view of those facts publicly available microarray datasets from RSV-infected BEAS-2B cells were analyzed with linear model-based statistics and the platform for functional analysis InnateDB. …”
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Diffuse panbronchiolitis as a rare complication of thymectomy and radiation therapy in a patient with thymoma: a case report by Ye Lu, Qi Qi, Dan Qu, Yu Chen

“…BackgroundDiffuse panbronchiolitis (DPB) is an uncommon respiratory disorder characterized by the presence of respiratory bronchiolitis and persistent inflammation in adjacent tissues, which can be effectively treated with early diagnosis and intervention. …”
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Perfusion Imaging in Autoimmune Encephalitis by Deepak Vallabhaneni, Muhammad Atif Naveed, Rajiv Mangla, Awss Zidan, Rashi I. Mehta

“…Encephalitis is characterized by inflammation of brain tissue and has various infectious and noninfectious causes. …”
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Synthesis and Anti-Inflammatory Activity of a Novel Series of Diphenyl-1,2,4-triazoles and Related Derivatives by Swapna Cherala, Harikiran Lingabathula, Rama Ganta, Srinivas Ampati, Sarangapani Manda

“…Among all the newly synthesized derivatives, Compounds 4Ia-4Ic and Compounds 4IIa-4IId were reduced the inflammation very significantly (p<0.0001), thus these compounds showed promising anti-inflammatory activity and only one compound (4Id) showed moderate anti-inflammatory activity (p<0.05).…”
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Why is it necessary to screen for periodontal disease in diabetic patients? by Rucsandra Elena Danciulescu Miulescu, Diana Loreta Paun, Loreta Guja, Oana Alexandra Mladin, Radu Ilinca, Iosif Cosmin Trebuian, Iuliana Gherlan

“…Periodontal diseases include gingivitis (inflammation of gingiva caused by the bacterial biofilm) and periodontitis involving loss of the supporting structures around the teeth, respectively cementum, periodontal ligament and alveolar bone. …”
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Changes in cortisol secretion and the role of the glucocorticoid receptor in the development of the immune response in patients with SARS-CoV-2 infection by Malvina Todorova, Katya Todorova

“…The detailed study of functional changes in cortisol secretion in response to SARS-CoV-2-associated inflammation provides a new horizon for scientific research following recovery from COVID-19.…”
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