Association between anti-Helicobacter pylori immunoglobulin G status and coronary artery disease among hypertensives: Myth or fact? by Gowri Subbiah, Anushiya Periyannan, Poongodi Lakshmi Santhanakumarasamy, Surendar Subramanian, Sumathi Ramalingam

“…Background: Chronic persistent inflammation associated with Helicobacter pylori (H. pylori) infection accelerates vascular complications which are prone to cause atherogenesis and coronary artery disease (CAD). …”
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Extracellular vesicles in thalassemia: Mechanisms, implications, and therapeutic potential by Shahzad Ali Jiskani

“…These complications can lead to a variety of severe health issues, including chronic inflammation, organ dysfunction, thrombosis, vascular abnormalities, and systemic iron overload. …”
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Promotion Mechanisms of Stromal Cell-Mediated Lung Cancer Development Within Tumor Microenvironment by Wu S, Hu Y, Sui B

“…This review aims to explore the mechanisms through which stromal cells in the tumor microenvironment promote lung cancer development, with a particular focus on how immune cells, tumor-associated fibroblasts, and endothelial cells contribute to immune suppression, inflammation, and angiogenesis. The goal is to provide new insights and potential strategies for the diagnosis and treatment of lung cancer.Keywords: tumor microenvironment, lung cancer, stromal cells, immune cells, cancer-associated fibroblasts, endothelial cells…”
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Platelet-white cell ratio is more strongly associated with mortality than other common risk ratios derived from complete blood counts by Brody H. Foy, Jonathan C. T. Carlson, Aaron D. Aguirre, John M. Higgins

“…Here we show that the platelet-to-white-cell ratio, which was selected based on this conserved recovery pattern, is more strongly associated with mortality than other blood count markers and ratios in four important illnesses involving acute inflammation: COVID-19, acute heart failure, myocardial infarction, and stroke. …”
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Editorial: Insights in clinical and translational physiology: 2023 by Gaetano Santulli, Gaetano Santulli, Gaetano Santulli, Markus W. Hollmann, Christina M. Pabelick, Johannes J. Van Lieshout, Johannes J. Van Lieshout

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COVID-19 and post-disease features in patients with obesity by Ekaterina S. Frolova, Pavel P. Veselovsky, Galina A. Chumakova, Nadezhda G. Veselovskaya, Anna V. Ott

“…Fatty tissue is known to support chronic low-grade inflammation and has its own endocrine activity. Over time, it became obvious that some patients still have consequences following the acute phase of COVID-19, which in some cases lead to irreversible changes in the body and reduced quality of life. …”
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Type 2 Diabetes Mellitus and its Relationship with Obesity by Lina Neri Espinosa Pire, Iruma Alfonso González, Michelle Ariana Calvache Vargas, Holger Alexander Lozano Ati

“…The insulin resistance observed in diabetic patients with obesity is caused by inflammation and the presence of immune cells in adipose tissue. …”
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Lifestyle Issues in Children and Adolescents with Chronic Inflammatory Bowel Diseases by P Sherman, A Griffiths, M Marcon, C Smith, R Geist

“…The goals of therapy in chronic inflammatory bowel diseases in pediatrics include decreasing mucosa! inflammation, the restoration of optimal growth and pubertal development, and the return to a normal, age-appropriate lifestyle. …”
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Evaluation of hematologic parameters in children with Down syndrome by Hasibe Artaç, Hülya Özdemir

“…In this study, we aimed to investigate peripheral blood-derived inflammation biomarkers such as neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and eosinophil/monocyte ratio in patients with Down syndrome. …”
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A Molecular and Whole Body Insight of the Mechanisms Surrounding Glucose Disposal and Insulin Resistance with Hypoxic Treatment in Skeletal Muscle by R. W. A. Mackenzie, P. Watt

“…Indeed, hypoxia has been widely implicated in the development of insulin resistance either via the direct action on insulin receptor substrate (IRS) and protein kinase B (PKB/Akt) or indirectly through adipose tissue expansion and systemic inflammation. Yet hypoxia is also known to encourage glucose transport using insulin-dependent mechanisms, largely reliant on the metabolic master switch, 5′ AMP-activated protein kinase (AMPK). …”
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Tophaceous Gout and Renal Insufficiency: A New Solution for an Old Therapeutic Dilemma by Anne-Kathrin Tausche, Carsten Wunderlich, Martin Aringer

“…After initial worsening of inflammation in the first weeks, gouty attacks stopped and all tophi resolved within the following 10 months. …”
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New insights into constitutive neutrophil death by Tong Chen, Qian Ren, Fengxia Ma

“…Constitutive neutrophil death (CND) contributes to neutrophil homeostasis and inflammation resolution. CND has long been considered to be apoptotic until our findings reveal that it was a heterogeneous combination of diverse death. …”
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Successful Diagnosis and Management of Superior Orbital Fissure Syndrome Secondary to Lung Adenocarcinoma: A Case Report by Wang Y, Zhao X

“…Yufang Wang, Xiangrong Zhao Department of Radiotherapy, Liaocheng Hospital Affiliated to Shandong First Medical University (Liaocheng People’s Hospital), Liaocheng, Shandong, People’s Republic of ChinaCorrespondence: Xiangrong Zhao, Email zxrzai@163.comIntroduction: Superior orbital fissure syndrome (SOFS) is a rare condition that involves damage to multiple structures within the superior orbital fissure, often caused by trauma, inflammation, or tumors. Lung adenocarcinoma, known for its propensity to metastasize, can lead to orbital metastases, which can manifest as SOFS. …”
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Persistent Suppression of Type 1 Diabetes by a Multicomponent Vaccine Containing a Cholera Toxin B Subunit-Autoantigen Fusion Protein and Complete Freund’s Adjuvant by Béla Dénes, István Fodor, William H. R. Langridge

“…Systemic coinoculation of prediabetic mice with recombinant vaccinia virus rVV-CTB::GAD and undiluted or 10-fold diluted CFA demonstrated a significant decrease in hyperglycemia and pancreatic islet inflammation in comparison with control animals during 17–61 and 17–105 weeks of age, respectively. …”
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Botanicals in human nutrition: focus on bioactive food-derived compounds on gut microbiota in gastrointestinal inflammatory diseases by Emanuele Rinninella, Giordana Galeazzi, Elisa Gianferrari, Sabrina Putzu, Pauline Raoul, Marco Cintoni, Francesca Bugli, Maria Cristina Mele, Maura Di Vito

“…We found preclinical and clinical studies confirming a striking potential role of these nutraceuticals in reducing gut inflammation in such conditions through gut eubiosis restoration. …”
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The Nicotinic Acetylcholine Receptor as a Target for Antidepressant Drug Development by Noah S. Philip, Linda L. Carpenter, Audrey R. Tyrka, Lawrence H. Price

“…This receptor, which is distributed widely in regions of the brain associated with depression, is also implicated in other important processes that are relevant to depression, such as stress and inflammation. The two classes of drugs that target nAChRs can be broadly divided into mecamylamine- and cytisine-based compounds. …”
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Peroxisome Proliferator-Activated Receptor Alpha Target Genes by Maryam Rakhshandehroo, Bianca Knoch, Michael Müller, Sander Kersten

“…The peroxisome proliferator-activated receptor alpha (PPARα) is a ligand-activated transcription factor involved in the regulation of a variety of processes, ranging from inflammation and immunity to nutrient metabolism and energy homeostasis. …”
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Exosome-Like Vesicles as New Mediators and Therapeutic Targets for Treating Insulin Resistance and β-Cell Mass Failure in Type 2 Diabetes Mellitus by Qian Ge, Xin Xin Xie, Xiaoqiu Xiao, Xi Li

“…Pathologic conditions associated with type 2 diabetes (such as high blood glucose, inflammation, hypoxia, and fatty acids) can alter the quantity and components of ELVs secreted from the pancreas or peripheral insulin-targeting tissues. …”
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The Angiotensin II Type 2 Receptor in Brain Functions: An Update by Marie-Odile Guimond, Nicole Gallo-Payet

“…If confirmed, these new pharmacological tools should help to improve impaired cognitive performance, not only through its action on brain microcirculation and inflammation, but also through more specific effects on neurons. …”
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Inhibition of Glycogen Synthase Kinase and the Neuroprotective Function of Conjugated ZnO-Osthol Nanoparticles in Alzheimer’s Disease by Nahed S. Alharthi, Fahad M. Aldakheel, Abdulkarim S. Binshaya

“…The mechanism of this effect is still unknown, although the effect of osthol on Aβ-induced inflammation is neuroprotective in AD and supplementation with zinc might prevent or delay the onset of dementia. …”
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