Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue by Ayu Safitri Sholihah, I Gusti Ayu Nyoman Danuyanti, Siti Zaetun, Pancawati Ariami, Ersandhi Resnhaleksmana

“…At the same time, the C-Reactive Proteins are used to see the presence of inflammation due to infections such as Dengue Virus infection. …”
Get full text

THE BENEFICIAL EFFECTS OF OLIVE TREE (OLEA EUROPAEA L.) IN THE NUTRITIONAL, PHARMACEUTICAL AND INDUSTRIAL APPLICATION: A REVIEW by Muhammad SHAFIQ, Muhammad Zafar IQBAL, Mohammad ATHAR

“…The potential of O. europaea plant extract showed antidiabetic, anticancer, asthma, cholesterol, uric acid, diarrhea, inflammation, blood pressure, antiheart and antiarthritis treatment. …”
Get full text

The exercise-induced inflammatory response in inflammatory bowel disease: A systematic review and meta-analysis. by Kelly A Baker, Timothy D Miller, Frank E Marino, Tegan E Hartmann

“…<h4>Conclusion</h4>Heterogeneity among the identified literature may have led to exercise interventions being ineffective in reducing inflammation. Although the limited number of eligible studies may reduce the reliability of results, it emphasises the need for additional research in this domain. …”
Get full text

A Novel Immune-Related Three-Gene Signature and Immune Infiltration Insights in Psoriasis and Chronic Kidney Disease by Yin T, Zhang T, Ma L

“…Through further functional analysis, these genes were found to be primarily involved in the activation of inflammation and innate immune responses. Subsequently, six hub genes were determined using five topological algorithms. …”
Get full text

A New Hope for the Patients of Non‐Alcoholic Steatohepatitis: FDA Gives Green Signal for Resmetirom Use by Abdul Haseeb Hasan, Muhammad Ali Abid, Muhammad Hafi Abid, Laiba Suhail, Abubakar Nazir

“…ABSTRACT Background and Aims Non‐Alcoholic Steatohepatitis (NASH), a severe form of Non‐Alcoholic Fatty Liver Disease (NAFLD), is characterized by inflammation and fibrosis in the liver, often progressing to cirrhosis and hepatocellular carcinoma. …”
Get full text

Effect of opercular deformity on morphological and transcriptomic profiling of gills in golden pompano (Trachinotus ovatus) by Yuwei Wu, Qian Ma, Dihao Huang, Liuyong Wang, Qiling Zhou, Chunli Ran, Gang Chen

“…KEGG pathway enrichment analysis of the DEGs indicated notable enrichment in pathways related to immune response and inflammation, including Staphylococcus aureus infection, leukocyte transendothelial migration, tight junction, and cell adhesion molecules pathways. …”
Get full text

Computer modeling of the peculiarities in the interaction of IL-1 with its receptors in schizophrenia by N. Yu. Chasovskikh, A. A. Bobrysheva, E. E. Chizhik

“…One of the primary theories regarding the development of schizophrenia revolves around genetics, indicating the involvement of hereditary factors in various processes, including inflammation. Research has demonstrated that inflammatory reactions occurring in microglia can impact the progression of the disease. …”
Get full text

Toxicity and antioxidant assessment of ethanol leaf extract of Hibiscus surattensis in Wistar rats: hepatotoxicity evaluation by Israel Kevin Umana, Tobechukwu Anthony Tochukwu, Enoluomen Ehigiator, Chinedu Joseph Ikem, Godswill James Udom, Akinyele Olubiyi Akinsola

“… Hibiscus surattensis is a medicinal plant with a vast beneficial use in the management and cure of a variety of diseases, ranging from urethritis to inflammation and vertigo among others. Notwithstanding the population's increasing use of it, particularly in rural regions, there is still lack of adequate investigation into its toxicity profile. …”
Get full text

Association between dietary inflammatory index and osteoporosis in the US population: evidence from NHANES 2003–2010 by Zhiwen Liu, Huanling Jian, Zijing Peng, Sicheng Xiong, Zhihai Zhang

“…LASSO regression identified key dietary factors, which were used to build a nomogram with an AUC of 83.6%, indicating strong predictive accuracy.ConclusionA higher DII is strongly linked to increased osteoporosis risk, underscoring the importance of reducing dietary inflammation to help prevent osteoporosis.…”
Get full text

Deciphering the significance of neutrophil to lymphocyte and monocyte to lymphocyte ratios in tuberculosis: A case-control study from southern India [version 2; peer review: 2 appr... by Poorva Bakshi, Shikha Jayasheelan, Rakshatha Nayak, Sharada Rai

“…Neutrophils, monocytes, and lymphocytes are crucial in the pathogenesis of granulomatous inflammation and immune reactions. We investigated the usefulness of the haematological parameters and their ratios, like the Neutrophil to Lymphocyte ratio (NLR) and Monocyte to Lymphocyte ratio (MLR), for diagnosing tuberculosis. …”
Get full text

Genetics of Inflammatory Bowel Disease: Current Understanding and Future Directions by P. K. Chandra Sekar, R. Veerabathiran

“…These genetic variants, integral to IBD's etiology of IBD, have functional significance because they perturb immune regulation, compromise epithelial barrier integrity, and disrupt mucosal homeostasis, collectively contributing to intestinal inflammation through diverse mechanisms. Early detection of IBD is paramount for arresting disease progression and underscoring the importance of prognostic testing and genetic screening, especially in cases with familial predispositions or very early onset IBD. …”
Get full text

Hijacking of the nervous system in cancer: mechanism and therapeutic targets by Yu Zhang, Qili Liao, Xuyang Wen, Jiayan Fan, Tifei Yuan, Xuemei Tong, Renbing Jia, Peiwei Chai, Xianqun Fan

Get full text

Therapeutic potential of targeting the IRF2/POSTN/Notch1 axis in nucleus pulposus cells for intervertebral disc degeneration by Daxue Zhu, Zhaoheng Wang, Shijie Chen, Yanhu Li, Xuewen Kang

“…Abstract Background Intervertebral disc degeneration (IDD) is a leading cause of low back pain, often linked to inflammation and pyroptosis in nucleus pulposus (NP) cells. …”
Get full text

Gram-Negative Bacterial Lipopolysaccharide Stimulates Activin A Secretion from Human Amniotic Epithelial Cells by Yumiko Abe, Risa Marukawa, Nami Tsuru, Maki Sato, Hiroko Matsuda, Hisanobu Sadakata, Takashi Kameda, Takashi Minegishi

“…Activin A is involved in inflammation. The present study was performed to clarify if lipopolysaccharide, a component of Gram-negative bacteria, stimulates activin A secretion from human amniotic epithelial cells and to determine if activin A plays a role in amnionitis. …”
Get full text

Regulation of miRNAs in obesity and diabetes by Eva Maher, Ava O'Meara, Cathy Brougham

“…Adipose derived stem cells (ADSCs) are promising cell models of obesity, obesity-related inflammation and diabetes. Furthermore, miRNA expression profiles have emerged as promising targets for the novel treatment of diseases such as obesity. …”
Get full text

Serum hepcidin level with iron profile assay might replace bone marrow iron study as a diagnostic tool for evaluation of anemia in elderly without chronic renal disease by Sukdev Manna, Sankha Shubhra Chakrabarti, Rohit Singh, Indrajeet Singh Gambhir

“…Methodology: Hundred elderly patients (≥60 years of age) having iron deficiency anemia (IDA) or anemia of chronic disease/inflammation (ACD) were the study subjects with 15 age-matched healthy controls. …”
Get full text

DA5-CH and Semaglutide Protect against Neurodegeneration and Reduce α-Synuclein Levels in the 6-OHDA Parkinson’s Disease Rat Model by Lingyu Zhang, Chun Li, Zijuan Zhang, Zhenqiang Zhang, Qian-Qian Jin, Lin Li, Christian Hölscher

“…Both drugs reduced the apomorphine-induced rotational behavior and alleviated dopamine depletion and the inflammation response in the lesioned striatum as shown in reduced IL-1β and TNF-α levels, with DA5-CH being more effective. …”
Get full text

Helicobacter pylori CagA and IL-1β Promote the Epithelial-to-Mesenchymal Transition in a Nontransformed Epithelial Cell Model by Haruki Arévalo-Romero, Isaura Meza, Gabriela Vallejo-Flores, Ezequiel M. Fuentes-Pananá

“…H. pylori/CagA-induced chronic inflammation triggers a series of gastric lesions of increased severity, starting with gastritis and ending with cancer. …”
Get full text

Steatohepatitis Is Not Associated with an Increased Risk for Fibrosis Progression in Nonalcoholic Fatty Liver Disease by Hannes Hagström, Olof Elfwén, Rolf Hultcrantz, Per Stål

“…The majority of NAFLD patients have fatty liver without inflammation (nonalcoholic fatty liver, NAFL), whereas a minority develop steatohepatitis (nonalcoholic steatohepatitis, NASH). …”
Get full text

Metallothionein II treatment mitigates rotenone-induced neurodegeneration in zebrafish models of Parkinson’s disease by Yong Hui Nies, Wei Ling Lim, Norwahidah Abd Karim, Mohamad Fairuz Yahaya, Seong Lin Teoh

“…Treatment with hMT2, especially in the co-treatment group, ameliorated these deficits by restoring locomotor activity, dopamine levels, and dopaminergic neuron counts while reducing oxidative stress and inflammation, and improving mitochondrial function.DiscussionThese results suggest that hMT2 exhibited neuroprotective effect in the PD model zebrafish. …”
Get full text