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5701
Pathogenic and therapeutic role of bile acids at reflux-gastritis
Published 2015-03-01“…Reflux-gastritis is chemical type gastritis, morphologically manifested by foveolar hyperplasia, edema, proliferation of smooth-muscle fibres of lamina propria, insignificant chronic inflammation. There is evidences of relation of intestinal metaplasia to duodenogastric reflux (DGR). …”
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5702
Evaluating the effect of virgin coconut oil pulling on viral load, bacterial load and inflammatory mediator levels in chronic periodontitis – A clinical study
Published 2025-01-01“…Background and objective: Periodontitis and dental caries are among the most prevalent oral diseases, with chronic periodontitis being a multifactorial, infectious condition that leads to inflammation in the supporting structures of the teeth, progressive attachment loss, and bone resorption. …”
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5703
The Impact of Surgical Trauma, BMI and Analgesics Intake on Postoperative Pain after Periapical Surgery in the Anterior Maxillary Region
Published 2024-01-01“…Study design: The study included 30 healthy, non-smoker adults of both genders, with an indication for periapical surgery on a single tooth in the upper anterior region, no history of prior surgery, no allergies to lidocaine with adrenaline or ibuprofen, no acute inflammation or pain, and a PAI of 3, 4, or 5. A single surgical team treated all patients by following the same surgical protocol. …”
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5704
Expression of Duodenal Iron Transporter Proteins in Diabetic Patients with and without Iron Deficiency Anemia
Published 2018-01-01“…In patients with T2DM and IDA, duodenal iron transport protein expression might be dependent on body iron stores rather than by chronic inflammation or diabetes per se.…”
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5705
Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice
Published 2016-01-01“…Obesity and metabolic syndrome and associated adiposity are a systemic condition characterized by increased mitochondrial dysfunction, inflammation, and inhibition of antioxidant genes, HO-1, and EETs levels. …”
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5706
Negative Pressure Smart Patch to Sense and Heal the Wound
Published 2025-01-01“…Compared with NPWT, NPSP projects a promising approach to removing bacteria, reducing local inflammation, and accelerating healing in a short period of time.…”
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5707
Atomized Neutrophil Membrane-coated MOF Nanoparticles for Direct Delivery of Dexamethasone for Severe Pneumonia
Published 2025-01-01“…In a mouse model of lipopolysaccharide (LPS)-induced pneumonia, UiO66-Dex@NMP significantly reduced lung inflammation compared to both the control model and Dex administered via inhalation. …”
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5708
Systemic Candida parapsilosis Infection Model in Immunosuppressed ICR Mice and Assessing the Antifungal Efficiency of Fluconazole
Published 2015-01-01“…Postmortem and histopathological examinations presented fugal-specific lesions in multiorgans, especially in kidneys, characterized by inflammation, numerous microabscesses, and fungal infiltration. …”
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5709
Dupilumab for treatment of primary cutaneous amyloidosis in adults: two case reports and literature review
Published 2025-02-01“…Dupilumab, a human monoclonal antibody targeting for interleukin (IL)-4/13 receptor α chain, is widely applied in type 2 inflammation diseases treatment. This article reported two cases of refractory LA successfully treated with dupilumab and reviewed publications reporting dupilumab treatment for PCA.…”
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5710
The gut microbiota‐derived metabolite indole‐3‐propionic acid enhances leptin sensitivity by targeting STAT3 against diet‐induced obesity
Published 2024-12-01“…IPA or Clostridium sporogenes supplement effectively controls weight gain, improves glucose metabolism, and reduces inflammation in DIO mice. IPA fails to achieve such effects in ob/ob mice, while exogenous leptin administration restores the therapeutic effect of IPA. …”
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5711
Genomic Introgression Between Critically Endangered and Stable Species of Darwin's Tree Finches on the Galapagos Islands
Published 2025-01-01“…Alleles were annotated to genes associated with inflammation, immunity, brain function and development. …”
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5712
Role of Janus Kinase inhibitors in the management of pulmonary involvement due to Long COVID-19 disease: A case control study
Published 2023-07-01“…CONCLUSION: JAKi can be used as immunomodulatory drugs in hypoxic OSC cases having evidence of ongoing inflammation.…”
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5713
Incidence and prognosis associated with troponin elevation after cardiac surgery: a prospective cohort study
Published 2022-08-01“…However, numerous confounding elements, such as inflammation, liver and renal function biomarkers, have been associated with troponin variations. …”
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5714
Inflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles
Published 2025-01-01“…Our findings illuminate the personalized nature of corona formation under a dynamic inflammatory condition and its impact on NP-mediated immune activation profiles and inflammation, suggesting that disease progression-related alterations in plasma composition can manifest in the corona to cause unintended toxicity and altered therapeutic efficacy.…”
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5715
The Association of Neutrophil/Lymphocyte and Platelet/Lymphocyte Ratios and Hematological Parameters with Diagnosis, Stages, Extrapulmonary Involvement, Pulmonary Hypertension, Res...
Published 2020-01-01“…Sarcoidosis is a rare disease characterized by granulomatous inflammation in affected organs, primarily in lungs. …”
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5716
CD22 modulation alleviates amyloid β-induced neuroinflammation
Published 2025-02-01“…Our data highlights the importance of sCD22 in driving neuroinflammation and the dual mechanism of targeting CD22 to resolve Aβ-induced inflammation and promote Aβ phagocytosis.…”
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5717
Extraction, GC-MS analysis, cytotoxic, anti-inflammatory and anticancer potential of Cannabis sativa female flower; in vitro, in vivo and in silico
Published 2025-02-01“…The concentration of serum biomarkers of inflammation and tumor progression was substantially reduced in treated groups compared to the control group, which proves the synergistic effects of these cannabinoids in breast cancer therapy. …”
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5718
The beneficial effects of curcumin on aging and age-related diseases: from oxidative stress to antioxidant mechanisms, brain health and apoptosis
Published 2025-01-01“…These pathways are involved in cellular senescence and inflammation, and their modulation can improve cell function and help prevent disease. …”
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5719
Anti-colon cancer activity of water-soluble polysaccharides extracted from Gloeostereum incarnatum via Wnt/β-catenin signaling pathway
Published 2021-07-01“…Compared with vehicle-treated mice, GIPS effectively reduced the levels of interleukin (IL)-1β, IL-4, IL-6, IL-17, IL-22, tumor necrosis factor (TNF)-α, matrix metalloproteinase (MMP)-2, and enhanced the levels of IL-15 and IL-18 in serum and/or colon tissues, which suggested its anti-inflammation of GIPS. GIPS suppressed nuclear aggregation of β-catenin, affected the expression of WNT1 and related proteins, thereby regulated the activation of the Wnt signaling. …”
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5720
Nonalcoholic Fatty Liver Disease in Patients Investigated for Elevated Liver Enzymes
Published 2003-01-01“…NAFLD was associated with a spectrum of changes in the liver ranging from mild steatosis to more significant steatosis with inflammation and fibrosis. Cases of NAFLD with steatosis and mixed inflammatory infiltration but lacking ballooning degeneration or fibrosis were prevalent in young (20 to 40 years of age) patients with no other significant medical history except for obesity. …”
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