Orexitropic Signaling Proteins in Obese Children by Ljiljana Saranac, Bojko Bjelakovic, Hristina Stamenkovic, Borislav Kamenov

“…Adipose tissue is not only the main organ for energy storage, but it also has endocrine properties, producing “adipokines” responsible for energy homeostasis, insulin sensitivity, and inflammation. Leptin, produced by adipocytes, is the key hormone in appetite regulation and suppression of orexigenic, hypothalamic neuropeptide Y (NPY). …”
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Tetramethylpyrazine promotes osteo-angiogenesis during bone fracture repair by Jiangbo Ai, Jingzhou Zheng

“…Histopathological changes were observed in the rats from each group using H&E staining. The levels of inflammation and coagulation markers in rats were evaluated by ELISA. …”
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Cardiac Tamponade: A Rare Manifestation of Familial Mediterranean Fever by Abdolreza Malek, Tina Zeraati, Ariane Sadr-Nabavi, Niloofar Vakili, Mohammad Reza Abbaszadegan

“…Familial Mediterranean fever (FMF) typically presents with recurrent attacks of fever and serosal inflammation with peritoneum, pleura, and synovium. We usually do not expect pericardial involvement at the early stages. …”
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Percutaneous Fine Needle Biopsy in Pancreatic Tumors: A Study of 42 Cases by Piotr Lewitowicz, Jaroslaw Matykiewicz, Jacek Heciak, Dorota Koziel, Stanisław Gluszek

“…In a group we are 23 cases of cancer, 12 cases of inflammation and 7 cases of cellular atypia for which 2 cases of IPMN were included. …”
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Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance. by Magdalena Widziolek, Anna Mieszkowska, Magdalena Marcinkowska, Bartlomiej Salamaga, Justyna Folkert, Krzysztof Rakus, Magdalena Chadzinska, Jan Potempa, Graham P Stafford, Tomasz K Prajsnar, Craig Murdoch

“…Porphyromonas gingivalis (Pg) is a keystone pathogen in periodontitis, a highly prevalent disease manifested by chronic inflammation of the periodontium, alveolar bone resorption and tooth loss. …”
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Effects of B-Blockers on the Sympathetic and Cytokines Storms in Covid-19. by Al-kuraishy, Hayder M., Al-Gareeb, Ali Ismail, Mostafa-Hedeab, Gomaa, Keneth Iceland, Kasozi, Zirintunda, Gerald, Aslam, Akhmed, Allahyani, Mamdouh, Welburn, Susan Christina, Batiha, Gaber El-Saber

“…The potential mechanisms of SS in Covid-19 are through different pathways such as hypoxia, which activate the central sympathetic center through carotid bodies chemosensory input and induced proinflammatory cytokines, which cross the blood-brain barrier and activation of the sympathetic center. b2-receptors signaling pathway play a crucial role in the production of pro-inflammatory cytokines, macrophage activation, and B-cells for the production of antibodies with inflammation exacerbation. b-blockers have anti-inflammatory effects through reduction release of pro-inflammatory cytokines with inhibition of NF-kB. …”
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Depressive and Negative Symptoms in the Early and Established Stages of Schizophrenia: Integrating Structural Brain Alterations, Cognitive Performance, and Plasma Interleukin 6 Lev... by Fabiana Corsi-Zuelli, Gary Donohoe, Siân Lowri Griffiths, Cristina M. Del-Ben, Andrew J. Watson, Tom Burke, Paris A. Lalousis, Declan McKernan, Derek Morris, John Kelly, Colm McDonald, Saahithh R. Patlola, Carmine Pariante, Nicholas M. Barnes, Golam M. Khandaker, John Suckling, Bill Deakin, Rachel Upthegrove, Maria R. Dauvermann

“…Cognitive deficits, reduced brain cortical thickness and volumes, and inflammation may contribute to depressive and negative symptoms, but pharmacological treatment and disease progression may confound the associations. …”
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Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome by Rosalie Matico, Karolien Grauwen, Dhruv Chauhan, Xiaodi Yu, Irini Abdiaj, Suraj Adhikary, Ine Adriaensen, Garcia Molina Aranzazu, Jesus Alcázar, Michela Bassi, Ellen Brisse, Santiago Cañellas, Shubhra Chaudhuri, Francisca Delgado, Alejandro Diéguez-Vázquez, Marc Du Jardin, Victoria Eastham, Michael Finley, Tom Jacobs, Ken Keustermans, Robert Kuhn, Josep Llaveria, Jos Leenaerts, Maria Lourdes Linares, Maria Luz Martín, Rosa Martín-Pérez, Carlos Martínez, Robyn Miller, Frances M Muñoz, Michael E Muratore, Amber Nooyens, Laura Perez-Benito, Mathieu Perrier, Beth Pietrak, Jef Serré, Sujata Sharma, Marijke Somers, Javier Suarez, Gary Tresadern, Andres A Trabanco, Dries Van den Bulck, Michiel Van Gool, Filip Van Hauwermeiren, Teena Varghese, Juan Antonio Vega, Sameh A Youssef, Matthew J Edwards, Daniel Oehlrich, Nina Van Opdenbosch

“…Abstract The NLRP3 inflammasome plays a pivotal role in host defense and drives inflammation against microbial threats, crystals, and danger-associated molecular patterns (DAMPs). …”
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Effects of pyrazosulfuron-ethyl on caudal fin regeneration in zebrafish larvae by Chenkai Ge, Zhijun Ye, Weitao Hu, Jingrong Tang, Huimin Li, Fasheng Liu, Xinjun Liao, Jianjun Chen, Shouhua Zhang, Zigang Cao

“…Using LPS to activate inflammation can effectively rescue the fin regeneration defects induced by pyrazosulfuron-ethyl. …”
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From Isolation to Application: Utilising Phage‐Antibiotic Synergy in Murine Bacteremia Model to Combat Multidrug‐Resistant Enterococcus faecalis by Fatma Al‐zahraa A. Yehia, Galal Yahya, Eslam M. Elsayed, Javier Serrania, Anke Becker, Salwa E. Gomaa

“…Histopathological analysis confirmed therapeutic synergy, showing reduced inflammation and improved hepatocyte regeneration. These findings underscore the potential of phage vB_EfaS_SZ1 as an adjunct to antibiotic therapy for resistant enterococcal bacteremia.…”
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Neurological damages in COVID‐19 patients: Mechanisms and preventive interventions by Sibani Sarkar, Subhajit Karmakar, Malini Basu, Pratyasha Ghosh, Mrinal K Ghosh

“…It is associated with systemic inflammation, myocardial infarction, neurological illness including ischemic strokes (e.g., cardiac and cerebral ischemia), and even death through multi‐organ failure. …”
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Immune‐dysregulation harnessing in myeloid neoplasms by Mohammad Jafar Sharifi, Ling Xu, Nahid Nasiri, Mehnoosh Ashja‐Arvan, Hadis Soleimanzadeh, Mazdak Ganjalikhani‐Hakemi

“…Moreover, inflammasome activation and sterile inflammation result in inflamed microenvironments and the development of myelodysplastic syndromes. …”
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Injectable Tumoricidal Neural Stem Cell-Laden Hydrogel for Treatment of Glioblastoma Multiforme—An In Vivo Safety, Persistence, and Efficacy Study by Jasmine L. King, Alain Valdivia, Shawn D. Hingtgen, S. Rahima Benhabbour

“…Results: The injectable CS hydrogel was well tolerated in mice with no signs of chronic local inflammation. Induced neural stem cells (iNSCs) persisted in the CS hydrogels for over 196 days in comparison to 21 days for iNSCs (cell injection) only. …”
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The impact of dietary fiber on colorectal cancer patients based on machine learning by Xinwei Ji, Lixin Wang, Pengbo Luan, Jingru Liang, Weicai Cheng

“…Through the screening of machine learning models, four key predictors for CRC patients were identified: PCT, PAB, ALB, and IL-1.ConclusionPostoperative dietary fiber administration in colorectal cancer enhances immune function, reduces disease-related inflammation, and inhibits tumor proliferation. Machine learning-based CRC prediction models hold clinical value.…”
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Outcome of Different Preemptive Analgesia Modalities in Patients Undergoing Total Knee Replacement Surgeries: A Prospective Randomized Study by Narendra Vaidya, Gourav S. Pawar, Anup P Gadekar, Nilesh A. Patil, Pravin Rameshrao Kutemate, Mohit Kolhapure

“…Conclusion: PA was found to reduce the severity of pain and inflammation after knee replacement surgery, resulting in reduced development of chronic pain after surgery. …”
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Evaluation of Histopathological Changes in Control Biopsies Which Taken 48 Sessions after NBUVB Phototherapy for Early-Stage Mycosis Fungoides by Ebru Zemheri, Seyma Ozkanli, Ilkin Zindanci, Serkan Senol, Ozge Akbulak, Elvan Turfanda, Mehtap Toprak, Duygu Kosemetin, Abdullah Aydin

“…Comparing by response, normalization of stratum corneum and epidermis, orthohyperkeratosis, decrease in linearly arranged cells, the lichenoid/patchy lichenoid infiltration, the loss of inflammation were statistically significant in responders group. …”
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Probiotic Bacterium-Derived p40, p75, and HM0539 Proteins as Novel Postbiotics and Gut-Associated Immune System (GAIS) Modulation: Postbiotic-Gut-Health Axis by Feray Gençer Bingöl, Duygu Ağagündüz, Ferenc Budán

“…The p40 protein, in particular, has been shown to support gut barrier activity and reduce inflammation, potentially through mechanisms involving epidermal growth factor receptor-dependent signaling. …”
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Antinociceptive Effect of Tephrosia sinapou Extract in the Acetic Acid, Phenyl-p-benzoquinone, Formalin, and Complete Freund’s Adjuvant Models of Overt Pain-Like Behavior in Mice by Renata M. Martinez, Ana C. Zarpelon, Talita P. Domiciano, Sandra R. Georgetti, Marcela M. Baracat, Isabel C. Moreira, Cesar C. Andrei, Waldiceu A. Verri, Rubia Casagrande

“…T. sinapou has been used in Amazonian countries traditional medicine to alleviate pain and inflammation. The purpose of this study was to evaluate the analgesic effects of T. sinapou ethyl acetate extract in overt pain-like behavior models in mice by using writhing response and flinching/licking tests. …”
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Xanthogranulomatous Pyelonephritis with Incomplete Double Ureter by Yutaro Hayashi, Takashi Kawahara, Yusuke Hattori, Kota Shimokihara, Sohgo Tsutsumi, Daiji Takamoto, Taku Mochizuki, Jun-ichi Teranishi, Yasushi Yumura, Yasuhide Miyoshi, Masako Otani, Hiroji Uemura

“…Xanthogranulomatous pyelonephritis (XGP) is a type of chronic renal inflammation that usually occurs in immunocompromised middle-aged women with chronic urinary tract infection or ureteral obstruction induced by the formation of ureteral stones. …”
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The Cytokine and Bone Protein Expression by Ellagic Acid-Hydroxyapatite in Bone Remodelling Model by Dyah Noviana Primasari, Intan Nirwana, Hendrik Setia Budi, Agung Satria Wardhana, Annisa Fitria Sari, Novita Novita, Andika Putri Setyawan, Meircurius Dwi Condro Surboyo, Khairul Anuar Shariff

“…Using a combination of the two materials results in reduced inflammation and increased osteogenesis. This study aimed to determine the effects of combining ellagic acid and hydroxyapatite in bone marker remodelling by analysing the expression of tumour necrosis factor-α (TNF-α), interleukin 10 (IL-10), bone morphogenetic 4 protein (BMP-4), and osteopontin (OPN). …”
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