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5541
Sirtuin activators as an anti-aging intervention for longevity
Published 2025-01-01“…The mammalian sirtuins comprise seven members that have a role in energy metabolism, DNA repair, inflammation, cell survival, apoptosis, cellular senescence, oxidative stress, and mitochondrial production. …”
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5542
Medical Gases: A Novel Strategy for Attenuating Ischemia—Reperfusion Injury in Organ Transplantation?
Published 2012-01-01“…In recent years, inhaled nitric oxide, carbon monoxide, and hydrogen sulfide have been increasingly explored as plausible novel medical gases that can attenuate IRI via multiple mechanisms, including microvascular vasorelaxation, reduced inflammation, and mitochondrial modulation. Here, we review recent advances in research utilizing inhaled nitric oxide, carbon monoxide, and hydrogen sulfide in animal and human studies of IRI and postulate on its future applications specific to solid organ transplantation.…”
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5543
Autoinflammation with arthritis and dyskeratosis an inflammasomopathy: Case report and review of literature
Published 2022-01-01“…Inherited disorders of the inflammasome pathway causes dysregulated inflammasome activation, which presents with inflammation and other clinical features linked to the defective protein. …”
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5544
The Involvement of Glycosaminoglycans in Airway Disease Associated with Cystic Fibrosis
Published 2011-01-01“…It has been assumed that these structural airway changes have occurred secondary to infection and inflammation, but recent studies suggest that glycosaminoglycan (GAG) remodelling may be an important independent parallel process. …”
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5545
Transplantation of Amniotic Membrane to the Subretinal Space in Pigs
Published 2012-01-01“…AM is well tolerated in the subretinal space, causes only limited inflammation, and is covered with a monolayer of pigmented cells when in contact with the host RPE. …”
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5546
Contemporary Evaluation and Management of the Diabetic Foot
Published 2012-01-01“…Even when properly managed, some of the foot ulcers do not heal and are arrested in a state of chronic inflammation. These wounds can frequently benefit from various adjuvants, such as aggressive debridement, growth factors, bioactive skin equivalents, and negative pressure wound therapy. …”
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5547
PPAR𝜸 and Oxidative Stress: Con(𝜷) Catenating NRF2 and FOXO
Published 2012-01-01“…Peroxisome-proliferator activator receptor γ (PPARγ) is a nuclear receptor of central importance in energy homeostasis and inflammation. Recent experimental pieces of evidence demonstrate that PPARγ is implicated in the oxidative stress response, an imbalance between antithetic prooxidation and antioxidation forces that may lead the cell to apoptotic or necrotic death. …”
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5548
CLINICAL-STATISTICAL STUDY ON THE FREQUENCY OF WISDOM TOOTH INCLUSION PATHOLOGY
Published 2024-12-01“…Including wisdom teeth is a common problem in dental practice, associated with significant complications such as gum inflammation, caries, root resorption of neighboring teeth, and cyst formation. …”
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5549
Cancer Cachexia: Mechanisms and Clinical Implications
Published 2011-01-01“…It involves multiple pathways: procachectic and proinflammatory signals from tumour cells, systemic inflammation in the host, and widespread metabolic changes (increased resting energy expenditure and alterations in metabolism of protein, fat, and carbohydrate). …”
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5550
Mesenchymal Stem Cells and Inflammatory Cardiomyopathy: Cardiac Homing and Beyond
Published 2011-01-01“…This paper gives an overview about how inflammation triggers the functionality of MSCs and how it induces cardiac homing. …”
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5551
Acute Adrenal Insufficiency Associated with Tuberculous Vertebral Osteomyelitis and Lymphadenopathy: Case Report
Published 2012-01-01“…Lumbar MRI showed vertebral body height loss and abnormal signal in L1 and L2; vertebral biopsy showed chronic, necrotic, caseating granulomatous inflammation consistent with tuberculous osteomyelitis. …”
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5552
Hallmarks of aging: middle-aging hypovascularity, tissue perfusion and nitric oxide perspective on healthspan
Published 2025-01-01“…These processes also involve oxidative stress and inflammation triggered by hypoxia.…”
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5553
Comparative analysis of C-Reactive protein levels among Non-comorbid, Comorbid, and Multimorbid Hospitalized COVID-19 patients
Published 2025-01-01“…Abstract Background C-reactive protein (CRP) is one of the most commonly monitored inflammatory markers in patients with COVID-19 to gain insight into the inflammation level in the body and to adopt effective disease management and therapeutic strategies. …”
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5554
Mesenchymal stromal cells-derived extracellular vesicles in cartilage regeneration: potential and limitations
Published 2025-01-01“…Recent evidence suggests that the beneficial effects of MSCs are largely mediated by their secreted small extracellular vesicles (sEVs), which have been shown to promote tissue repair and reduce inflammation. MSC-derived sEVs have shown promise in mitigating cartilage degradation and chondrocyte apoptosis, positioning them as a promising alternative to MSC-based therapies for OA treatment. …”
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5555
Functional status, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio as prognostic factors of one-year survival rate in elderly patients with advanced-stage non-small...
Published 2024-01-01“…Aging and chronic inflammation are related to its pathogenesis. Functional status, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio describe a chronic inflammation and correlate to the survival of older adults with advanced-stage (IIIB-IV) NSCLC. …”
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5556
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5557
Effects of Standardized Natural Citrus Extract on Growth, Gut Health, Carcass Quality, and Welfare of Broiler Chickens
Published 2025-01-01“…These effects could potentially be attributed to the reduction in inflammation and the enhanced utilization of nutrients. …”
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5558
The methyl-CpG binding domain 2 regulates peptidylarginine deiminase 4 expression and promotes neutrophil extracellular trap formation via the Janus kinase 2 signaling pathway in e...
Published 2025-12-01“…Inhibiting the expression of MBD2, JAK2, and PAD4 reduced NETs formation and decreased airway inflammation scores, total cell counts and neutrophil counts in BALF, and percentage of Th2 and Th17 cell in lung tissues, whereas increasing Treg cell counts. …”
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5559
Effects of heat stress abatement on behavioral response in lactating dairy cows prior to and following an intramammary lipopolysaccharide infusion
Published 2025-02-01“…However, deprivation of evaporative cooling does not have a significant effect on the lactating cow's behavioral responses to LPS induced mammary inflammation.…”
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5560
Characteristics of base materials and acrylates used in removable prosthetics in dental practice (review)
Published 2024-06-01“…It is worth remembering that removable prostheses are inherently combined irritants that have a whole set of negative effects on the mucous membrane of the prosthetic bed, leading to its chronic inflammation. The above-described negative properties of acrylic plastic became the impetus for the creation of other types of materials. …”
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