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5501
Lipid Droplet Surface Promotes 3D Morphological Evolution of Non‐Rhomboidal Cholesterol Crystals
Published 2025-01-01“…Abstract Cholesterol crystals, which cause inflammation and various diseases, predominantly grow in a platy, rhomboid structure on the plasma membranes but exhibit an uneven three‐dimensional (3D) architecture intracellularly. …”
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5502
Modulation Effects of Curcumin on Erythrocyte Ion-Transporter Activity
Published 2015-01-01“…Curcumin ((1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione), the yellow biphenolic pigment isolated from turmeric (Curcuma longa), has various medicinal benefits through antioxidation, anti-inflammation, cardiovascular protection, immunomodulation, enhancing of the apoptotic process, and antiangiogenic property. …”
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5503
The effect of different strains of Helicobacter pylori on platelet aggregation
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5504
Peroxisome proliferator–activated receptor delta and liver diseases
Published 2025-02-01“…PPAR-delta not only regulates physiologic processes of lipid, glucose, and bile acid metabolism but also attenuates pathologic responses to alcohol metabolism, inflammation, fibrosis, and carcinogenesis, and is considered an important therapeutic target in liver diseases. …”
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5505
Peroxisome Proliferator-Activated Receptor β/δ in the Brain: Facts and Hypothesis
Published 2008-01-01“…PPARβ could also regulate central inflammation and antioxidant mechanisms in the damaged brain. …”
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5506
Relationship between enriched environment and neurodegeneration: a review from mechanism to therapy
Published 2025-01-01“…This review delineated the impact of EE on the biological functions associated with NDs, emphasizing its role in enhancing neural plasticity, reducing inflammation, and bolstering cognitive performance. We discussed the molecular underpinnings of the effects of EE, including modulation of key signaling pathways such as extracellular regulated kinase 1/2 (ERK1/2), mitogen-activated protein kinases (MAPK), and AMPK/SIRT1, which were implicated in neuroprotection and synaptic plasticity. …”
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5507
Mesenchymal Stem Cells (MSCs): A Novel Therapy for Type 2 Diabetes
Published 2022-01-01“…Potential mechanisms of MSC-based intervention on multiple pathological processes of T2DM, such as β-cell exhaustion, hepatic dysfunction, insulin resistance, and systemic inflammation, are also delineated. Moreover, we highlight the importance of understanding the pharmacokinetics (PK) of transplanted cells and discuss the hurdles in MSC-based T2DM therapy toward future clinical applications.…”
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5508
Aneurysm and Neurocysticercosis: Casual or Causal Relationship? Case Report and Review of the Literature
Published 2011-01-01“…At surgery, a viable cysticercus without signs of inflammation or thickened leptomeninges was found in the distal position of the aneurysm. …”
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5509
Application of Low-Intensity Laser in the Treatment of Skeletal Muscle Injury in Runners
Published 2022-01-01“…The experimental results showed that a low-intensity laser can effectively alleviate muscle inflammation, reduce the number of cell damage, bring the mean and integral optical density of protein to the normal level significantly, and reduce the strain degree of exercise muscle. …”
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5510
Research Progress on Alleviatory Effects of 6-Gingerol and 6-Shogaol on Intestine Tight Junction Damage
Published 2024-12-01“…Through comprehensive analysis of clinical research and experimental results in recent years, it is found that 6-gingerol and 6-shogaol can improve the expression levels of tight junction-related proteins and maintain the integrity and biofunction of the intestinal barrier by inhibiting inflammation, oxidative stress and apoptosis as well as regulating the composition of intestinal microbiota. …”
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5511
SIRT1 Regulates Cognitive Performance and Ability of Learning and Memory in Diabetic and Nondiabetic Models
Published 2017-01-01“…In the present study, deacetylation, oxidative stress, mitochondrial dysfunction, inflammation, microRNA, and tau phosphorylation are considered in the context of mechanism and significance of SIRT1 in learning and memory in diabetic and nondiabetic murine models. …”
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5512
MINI DENTAL IMPLANTS: ADVANTAGES, LIMITATIONS AND CLINICAL APPLICABILITY
Published 2024-12-01“…Advanced biomaterials, such as titanium alloys, are essential for the success of mini-implants, ensuring osseointegration and reducing the risk of inflammation. In addition, essential oils, with antimicrobial and anti-inflammatory properties, help maintain peri-implant health, preventing infections and peri-implant complications. …”
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5513
Gut-Lung Axis in COVID-19
Published 2021-01-01“…The gut microbiome also plays major roles in immunity and inflammation. It also impacts pulmonary functions through the gut-lung axis. …”
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5514
Cortisol in Oral and Maxillofacial Surgery: A Double-Edged Sword
Published 2021-01-01“…One of its main functions is to decrease inflammation, particularly in areas where an inflammatory response is not necessary. …”
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5515
Modern Endoscopic Imaging in Diagnosis and Surveillance of Inflammatory Bowel Disease Patients
Published 2018-01-01“…Additionally, we discuss future directions and techniques as candidates for a superior inflammation imaging in the diagnosis and prediction of therapeutic response.…”
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5516
Telocytes in inflammatory bowel diseases: contributions to pathology and therapeutic potentials
Published 2025-01-01“…Inflammatory bowel diseases (IBD), which include Crohn’s disease (CD) and ulcerative colitis (UC), are characterized by chronic inflammation and fibrosis. While limited information is available on the fate of telocytes in this group of diseases, it has been suggested that loss/plasticity of telocytes can be among the key factors contributing to their pathogenesis. …”
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5517
The effects of the ketone body ?-hydroxybutyrate on the neuronal transcriptome
Published 2025-02-01“…We identified significantly altered (p<0.05) pathways associated with inflammation and immunity such as “regulation of proinflammatory cytokine production” and “modulation of inflammatory responses.” …”
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5518
Severe atopic dermatitis treated with Dupilumab in a CTLA-4-deficient patient: A case report and review of the literature
Published 2025-01-01“…Dupilumab, an IL-4 and IL-13 receptor antagonist, has demonstrated efficacy in controlling severe, recalcitrant atopic dermatitis by mitigating T helper 2-driven inflammation. We present a case of a 24-year-old male with cytotoxic T lymphocyte-associated antigen 4 haploinsufficiency and severe atopic dermatitis successfully managed with Dupilumab. …”
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5519
Noise-augmented directional clustering of genetic association data identifies distinct mechanisms underlying obesity.
Published 2022-01-01“…Analysis of the biological pathways underlying this cluster identifies inflammation as potentially explaining differences in the effects of increased body mass index on coronary heart disease.…”
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5520
Research Progress on Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Knee Osteoarthritis
Published 2025-01-01“…Knee osteoarthritis (KOA) is a prevalent degenerative joint disease characterized by synovial inflammation, cartilage loss. Often manifesting as joint pain and limited mobility, it severely affects the quality of life of patients. …”
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