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5441
Amyloid β-Related Angiitis Causing Coma Responsive to Immunosuppression
Published 2012-01-01“…Amyloid-beta-related angiitis (ABRA) is a form of CNS vasculitis in which perivascular beta-amyloid in the intracerebral vessels is thought to act as a trigger for inflammation mediated by CD68+ macrophages and CD3+ T lymphocytes. …”
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5442
Advances in the relationship between AP-1 and tumorigenesis, development and therapy resistance
Published 2025-01-01“…AP-1 is involved in various cellular processes, such as proliferation, differentiation, apoptosis and inflammation. For tumor cells, AP-1 is considered to be a driver whose activity is associated with dysfunction and the onset, development, invasion, and migration of cancer. …”
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5443
Spatial transcriptomic analysis identifies epithelium-macrophage crosstalk in endometriotic lesions
Published 2025-02-01“…Spatial transcriptomics highlighted increased signaling between the lesion epithelium and macrophages, emphasizing the role of the epithelium in driving lesion inflammation. We propose that the superficial endometriotic lesion epithelium orchestrates inflammatory signaling and promotes a pro-repair phenotype in macrophages, providing a new role for complement 3 in lesion pathobiology. …”
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5444
Protective effect of exercise on animals with sepsis: a systematic review of the existing literature
Published 2025-02-01“…And its possible mechanisms were involved improving the general condition of sepsis animals, pathological and cell number of organs, anti-inflammation, anti-oxidative stress, anti-DNA damage, and so on. …”
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5445
Pauci-Immune Necrotizing and Crescentic Glomerulonephritis with Membranous Lupus Nephritis, Fifteen Years after Initial Diagnosis of Secondary Membranous Nephropathy
Published 2015-01-01“…Pauci-immune necrotizing and crescentic glomerulonephritis (NCGN) refers to extensive glomerular inflammation with few or no immune deposits that may result in rapid decline in renal function. …”
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5446
Unmet needs in atopic dermatitis management: an expert consensus
Published 2022-07-01Get full text
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5447
Adipocyte-Specific Fatty Acid-Binding Protein (AFABP) and Chemerin in Association with Gestational Diabetes: A Case-Control Study
Published 2021-01-01“…These adipocytokines were related to insulin resistance, body mass index, and inflammation in pregnant women diagnosed with GDM.…”
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5448
Role of High-Density Lipoprotein Cholesterol (HDL-C) as a Clinical Predictor of Decompensation in Patients with Chronic Liver Disease (CLD)
Published 2021-01-01“…Introduction. Systemic inflammation triggered by bacterial products like lipopolysaccharides (LPS) in the circulation is an important factor leading to decompensation in patients with chronic liver disease (CLD). …”
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5449
Intercellular communication is crucial in the regulation of healthy aging via exosomes
Published 2025-02-01“…The hallmarks of aging encompass a variety of molecular categories (genomic, telomeric, and epigenetic), organelles (proteostasis, autophagy, and mitochondria), cellular components (including stem cells), systems (such as intercellular communication and chronic inflammation), and environmental factors (dysbiosis and nutrient sensing). …”
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5450
Sargachromenol from Sargassum micracanthum Inhibits the Lipopolysaccharide-Induced Production of Inflammatory Mediators in RAW 264.7 Macrophages
Published 2013-01-01“…In the present study, we investigated the anti-inflammatory effects of sargachromenol on lipopolysaccharide (LPS)-induced inflammation in murine RAW 264.7 macrophage cells and the underlying mechanisms. …”
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5451
Comprehensive Overview of Ketone Bodies in Cancer Metabolism: Mechanisms and Application
Published 2025-01-01“…At present, a burgeoning body of research is concentrating on the metabolism of KBs within tumors, investigating their roles as signaling mediators, drivers of post-translational modifications, and regulators of inflammation and oxidative stress. The ketogenic diet (KD) may enhance the sensitivity of various cancers to standard therapies, such as chemotherapy and radiotherapy, by exploiting the reprogrammed metabolism of cancer cells and shifting the metabolic state from glucose reliance to KB utilization, rendering it a promising candidate for adjunct cancer therapy. …”
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5452
Mycoplasma pneumoniae drives macrophage lipid uptake via GlpD-mediated oxidation, facilitating foam cell formation
Published 2025-03-01“…Atherosclerosis is characterized by chronic inflammation and lipid accumulation in the arterial wall, leading to plaque formation. …”
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5453
A Model of Insulin Resistance in Mice, Born to Diabetic Pregnancy, Is Associated with Alterations of Transcription-Related Genes in Pancreas and Epididymal Adipose Tissue
Published 2011-01-01“…Adult IR and control offspring were selected and we determined the mRNA expression of transcription factors known to modulate pancreatic and adipose tissue activities and inflammation. Results. We observed that serum insulin increased, and the mRNA of insulin gene transcription factors, Pdx-1, Nkx6.1 and Maf-A, were upregulated in IR mice pancreas. …”
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5454
Seronegative Arthritis and Whipple Disease: Risk of Misdiagnosis in the Era of Biologic Agents
Published 2019-01-01“…The second patient was a 55-year-old man, presenting with arthritis, fever, serositis, lymphadenopathy, thoracic rash, and systemic inflammation; at the beginning he was diagnosed as adult onset Still’s disease. …”
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5455
RASGRF2 as a potential pathogenic gene mediating the progression of alcoholic hepatitis to alcohol-related cirrhosis and hepatocellular carcinoma
Published 2025-01-01“…Abstract Background and aims Alcoholic hepatitis (AH) and hepatocellular carcinoma (HCC) are common liver diseases. Chronic inflammation caused by AH can progress to alcoholic cirrhosis (AC) and eventually HCC. …”
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5456
The influence of follicular fluid on the regulation of apoptosis and related genes during IVM of camel oocytes
Published 2025-01-01“…We recommend using higher dosage and measuring the expression levels of certain genes involved in programmed cell death and inflammation.…”
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5457
Oxidative Stress: A Link between Diabetes Mellitus and Periodontal Disease
Published 2014-01-01“…Our results showed that periodontal tissues in patients with T2D present significant inflammation, affecting both epithelial and connective tissues. …”
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5458
Association of Peripheral Monocyte Count with Soluble P-Selectin and Advanced Stages in Nasopharyngeal Carcinoma
Published 2018-01-01“…Introduction. Inflammation is widely recognized to play an important role in cancer progression and is related to thrombosis. …”
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5459
Common Organisms causing surgical site infection(SSI) in Postoperative patients in a tertiary care Hospital
Published 2022-12-01“…A diagnosis of SSI was based on specific parameters, including the detection of two or three cardinal signs of inflammation and the surgeon's confirmation of the diagnosis. …”
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5460
Determination of the levels of some selected metals in ocimum lamiifolium in Wolaita Zone, Southern Ethiopia
Published 2022-10-01“…Ex Benth (Damakese, in Amharic) is one of the well celebrated and most widely used home remedy for the treatment of a disease locally known as “Mitch” which is characterized by headache, fever, inflammation, joint pain, sweat, loss of appetite, etc. …”
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