The Impact of Autophagy on Cell Death Modalities by Stefan W. Ryter, Kenji Mizumura, Augustine M. K. Choi

“…Additionally, autophagy can modulate other vital processes such as programmed cell death (e.g., apoptosis), inflammation, and adaptive immune mechanisms and thereby influence disease pathogenesis. …”
Get full text

Atrial Cardiomyopathy: From Diagnosis to Treatment by Zheyu Liu, Tao Liu, Gang Wu

“…However, substantial evidence suggests that the relationship between cardiogenic embolism and AF is not so absolute, and that ACM may be an important, underestimated contributor to cardiogenic embolism events. Chronic inflammation, oxidative stress response, lipid accumulation, and fibrosis leading to ACM form the foundation for AF. …”
Get full text

Rapidly Progressive Pulmonary Apical Fibrosis and Parenchymal Destruction in a Patient with Ankylosing Spondylitis by Hasan Ulusoy, Nazmiye Tibel Tuna, Aslı Tanrivermis Sayit

“…Biopsy revealed no finding of malignancy, granulomatous inflammation, or vasculitis. The results of cultures were negative. …”
Get full text

Signaling Pathway of Nucleotide-Binding Oligomerization Domain-Containing Protein 1 and Potential Therapeutic Targets for Regulating the Gut Microbiota of Individuals with Gallston... by Sanjana Murali, Nandini Krishnamurthy, R. B. Devi Krishna, Shanthi Vijayaraghavan, S. Rajesh Kumar, Andrea Mary Francis

“…The essential receptor through which the innate immune system detects bacterial components and controls inflammation, namely, nucleotide-binding oligomerization domain-containing protein 1 (NOD1), is a major participant in the interaction. …”
Get full text

A Possible Relationship between Peri-Implantitis, Titanium Hypersensitivity, and External Tooth Resorption: Metal-Free Alternative to Titanium Implants by Andrea Enrico Borgonovo, Rachele Censi, Virna Vavassori, Mauro Savio, Dino Re

“…At clinical and radiographic examinations, tissue inflammation and vertical bone loss involved the new implants and the process of external resorption affected the teeth. …”
Get full text

Alzheimer’s Disease and <i>Porphyromonas gingivalis</i>: Exploring the Links by Ivana Shawkatova, Vladimira Durmanova, Juraj Javor

“…Indirect mechanisms, including systemic inflammation triggered by chronic periodontal infections, are also supposed to exacerbate neurodegenerative processes. …”
Get full text

The Caries Phenomenon: A Timeline from Witchcraft and Superstition to Opinions of the 1500s to Today's Science by John D. Ruby, Charles F. Cox, Naotake Akimoto, Nobuko Meada, Yasuko Momoi

“…Until the early 1800s most writers believed that caries was due to inflammation from surrounding diseased alveolar bone. …”
Get full text

Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos. by Xi Li, Guanghua Xiong, Manni Luo, Siwan Mao, Ruiying Zhang, Ziwei Meng, Juan Li, Xinjun Liao

“…Taken together, our data suggested that zebrafish PGRP-5 is involved in the innate immune defenses and regulated the neurobehavior and neuro-inflammation, which may provide new strategies for the treatment of neuro-inflammatory diseases in the aquatic organisms.…”
Get full text

Influence of Rosiglitazone on the Expression of PPARγ, NF-κB, and TNF-α in Rat Model of Ulcerative Colitis by Jing-Wei Mao, Hai-Ying Tang, Ying-De Wang

“…Rosiglitazone can alleviate colonic mucosal inflammation and have the protective role on UC by upregulating PPARγ expression and downregulating NF-κB and TNF-α expression.…”
Get full text

Glucoraphanin conversion into sulforaphane and related compounds by gut microbiota by Tetiana R. Dmytriv, Tetiana R. Dmytriv, Oleh Lushchak, Oleh Lushchak, Volodymyr I. Lushchak, Volodymyr I. Lushchak

“…We assume that sulforaphane alleviates intestinal inflammation and oxidative stress maintaining intestinal homeostasis and gut barrier integrity. …”
Get full text

Mass Cytometry Reveals the Imbalanced Immune State in the Peripheral Blood of Patients with Essential Hypertension by Rui Yang, Yuhong He, Honggang Zhang, Qiuju Zhang, Bingwei Li, Changming Xiong, Yubao Zou, Bingyang Liu

“…Mounting evidence has confirmed that essential hypertension (EH) is closely related to low-grade inflammation, but there is still a lack of in-depth understanding of the state of immune cells in the circulating blood of patients with EH. …”
Get full text

An Insight of Vitamin E as Neuroprotective Agents by Hui-Min Yap, Kwan-Liang Lye

“…TRF was reported to possess potent antioxidant, anti-inflammation, anticancer and cholesterol-lowering properties. …”
Get full text

Clinical Presentations and Characteristics of NSAIDs Hypersensitivity in a Tertiary Care Hospital in Indonesia: A Case Series by Nurmesa A, Zakiyah N, Insani WN

“…Adi Nurmesa,1,2 Neily Zakiyah,1,3 Widya Norma Insani1,3 1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, 40132, Indonesia; 2Department of Pharmacy, Dr Rivai Abdullah Regional General Hospital, Banyuasin, 30961, Indonesia; 3Center of Excellence for Pharmaceutical Care Innovation, Universitas Padjadjaran, Bandung, 40132, IndonesiaCorrespondence: Neily Zakiyah, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, 40132, Indonesia, Email neily.zakiyah@unpad.ac.idAbstract: Non-steroidal anti-inflammatory drugs (NSAIDs) are widely administered in all age groups due to their effectiveness in reducing fever, relieving pain, and reducing inflammation. However, they have also been identified as the second most common cause of drug-induced hypersensitivity reactions, after beta-lactam antibiotics. …”
Get full text

Underlying anti-hypertensive mechanism of the Mizuhopecten yessoensis derived peptide NCW in spontaneously hypertensive rats via widely targeted kidney metabolomics by Wenjun Xue, Wenzhu Zhao, Sijia Wu, Zhipeng Yu

“…The peptide NCW might regulate kidney metabolic disorder of SHRs to alleviate hypertension by suppressing inflammation and improving nitric oxide production under the regulation of linoleic acid metabolism, folate related pathways, synthesis and degradation of ketone bodies, pyrimidine metabolism, β-alanine metabolism, and retinal metabolism.…”
Get full text

Targeted Regulation Of Cgrp Gene Expression by A. F. Russo, P. L. Durham

“…The neuropeptide calcitonin gene-related peptide (CGRP) is a potent regulator of cerebral vascular tone and contributes to neurogenic inflammation. Clinical studies have shown that CGRP levels are elevated during the painful phase of migraine headache, then restored to baseline by antimigraine 5-HT1 drugs. …”
Get full text

Clinical Holistic Medicine: Chronic Infections and Autoimmune Diseases by Søren Ventegodt, Joav Merrick

“…The consciousness-based (holistic) medical toolbox might be useful in general practice and in cases of recurrent infections and chronic infection or inflammation. From our clinical experiences, there is hope for improvement from a number of diseases caused by disorders affecting the regulation of the immune system when the physician includes the holistic medical approach.Our scientific understanding of the connection between consciousness and cellular order is still limited. …”
Get full text

The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity by Niamh McGarry, Catherine M. Greene, Noel G. McElvaney, Sinéad Weldon, Clifford C. Taggart

“…This reduction in monocyte apoptosis may preserve monocyte function during inflammation resolution and promote infection clearance at mucosal sites.…”
Get full text

Recent advances in adipose-derived mesenchymal stem cell-derived exosomes for regulating macrophage polarization by Zhewei Dong, Yingli Fu, Zhongming Cai, Hao Dai, Yucang He

“…The anti-inflammatory and immunomodulatory properties of these exosomes provide new perspectives for therapeutic approaches for graft inflammation, bone healing, acute lung injury, kidney stones, myocardial infarction, and diabetes-related diseases. …”
Get full text

Effect of Interleukin and Hepcidin in Anemia of Chronic Diseases by Maha F. Yacoub, Hala Fouad Ferwiz, Fadwa Said

“…Anemia of chronic disease (ACD) also termed as the anemia of inflammation has been found to be associated with inflammations, chronic infections, and cancers, particularly in old age. …”
Get full text

Functional Parathyroid Cyst: A Rare Cause of Malignant Hypercalcemia with Primary Hyperparathyroidism—A Case Report and Review of the Literature by Areej Khan, Yusra Khan, Shahzad Raza, Ghulam Akbar, Monis Khan, Nauman Diwan, Wajih Rizvi

“…Physicians should be aware of the presence of hemorrhage, inflammation, and compressive symptoms in these cysts which mimic parathyroid carcinoma. …”
Get full text