Associations of carbohydrate quality and cardiovascular risk factors vary among diabetes subtypes by Katharina S. Weber, Sabrina Schlesinger, Janina Goletzke, Klaus Straßburger, Oana-Patricia Zaharia, Sandra Trenkamp, Robert Wagner, Wolfgang Lieb, Anette E. Buyken, Michael Roden, Christian Herder, for the GDS group

“…Conclusions Associations of carbohydrate quality parameters with blood lipids, subclinical inflammation, and fatty liver index differed between diabetes subtypes. …”
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Disrupting of IGF2BP3-stabilized CLDN11 mRNA by TNF-α increases intestinal permeability in obesity-related severe acute pancreatitis by Lihui Lin, Yansong Lin, Xianwen Guo, Ruoyi Zhang, Xin Ling, Zewen Zhang, Rong Lin, Zhen Ding

“…Moreover, we conducted anti-TNFα therapy and evaluated intestinal permeability and pancreatic inflammation in experimental obesity-related SAP. Results Downregulation of CLDN11 was observed in the intestinal epithelial cells of experimental obesity-related SAP. …”
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Carrageenan-Free Diet Shows Improved Glucose Tolerance and Insulin Signaling in Prediabetes: A Randomized, Pilot Clinical Trial by Leo Feferman, Sumit Bhattacharyya, Erin Oates, Nicole Haggerty, Tianxiu Wang, Krista Varady, Joanne K. Tobacman

“…Carrageenan is well known to cause inflammation and is used in laboratory experiments to study mediators and treatments of inflammation. …”
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Blood urea nitrogen-to-albumin ratio as a new prognostic indicator of 1-year all-cause mortality in patients with IPF by Shaobo Ge, Yuer Li, Rui Li, Jin Liu, Rui Zhang, Hongyan Fu, Jingjing Tang, Jie Zhang, Nali Zhang, Ming Zhang, Ming Zhang

“…BackgroundIdiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by chronic inflammation and progressive fibrosis. The blood urea nitrogen-to-albumin ratio (BAR) is a comprehensive parameter associated with inflammation status; however, it is unknown whether the BAR can predict the prognosis of IPF.MethodsThis retrospective study included 176 patients with IPF, and 1-year all-cause mortality of these patients was recorded. …”
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Screening of Anti-Inflammatory Components of Qin Jin Hua Tan Tang by a Multivariate Statistical Analysis Approach for Spectrum-Effect Relationships by Feipeng Duan, Yisheng Li, Meizhen Zhao, Tianyong Hu, Xinquan Pan, Yue Feng, Fang Ma, Shuqi Qiu, Yiqing Zheng

“…Qing Jin Hua Tan Tang (QJHTT) exerts therapeutic effects in patients with chronic obstructive pulmonary disease (COPD) by alleviating inflammation. However, the anti-inflammatory components of QJHTT have not yet been reported. …”
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Amantadine modulates novel macrophage phenotypes to enhance neural repair following spinal cord injury by Shijie Yang, Beibei Yu, Qing Zhang, Yongfeng Zhang, Longhui Fu, Bisheng Zhou, Haining Wu, Jianzhong Li, Shouping Gong

“…The modulation of macrophage phenotypes is thus considered a promising therapeutic strategy to mitigate inflammation and promote regeneration. Methods We employed microarray and single-cell RNA sequencing (scRNA-seq) to investigate gene expression changes and immune cell dynamics in mice following crush injury at 3 and 7 days post-injury (dpi). …”
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Exploring nutraceutical approaches linking metabolic syndrome and cognitive impairment by Rebecca Sonnino, Gea Ciccarelli, Simona Moffa, Laura Soldovieri, Gianfranco Di Giuseppe, Michela Brunetti, Francesca Cinti, Eleonora Di Piazza, Antonio Gasbarrini, Enrico C. Nista, Alfredo Pontecorvi, Andrea Giaccari, Teresa Mezza

“…Summary: Metabolic syndrome (MetS) and mild cognitive impairment (MCI) are interconnected conditions sharing common pathological pathways, such as inflammation and oxidative stress, leading to the concept of “metabolic-cognitive syndrome.” …”
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Intestinal rearrangement of biliopancreatic limbs, alimentary limbs, and common limbs in obese type 2 diabetic mice after duodenal jejunal bypass surgery by Heng Li, Heng Li, Jipei He, Jie Hou, Chengjun He, Xiaojiang Dai, Zhigao Song, Qing Liu, Zixin Wang, Hongyan Huang, Yunfa Ding, Tengfei Qi, Hongbin Zhang, Hongbin Zhang, Liangping Wu, Liangping Wu

“…Additionally, the surgery improved intestinal permeability and inflammation in the alimentary and common limbs, while reducing inflammation in the biliopancreatic limbs. …”
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Cysticerci Drive Dendritic Cells to Promote In Vitro and In Vivo Tregs Differentiation by Laura Adalid-Peralta, Asiel Arce-Sillas, Gladis Fragoso, Graciela Cárdenas, Marcos Rosetti, Didier Casanova-Hernández, Claudia Rangel-Escareño, Laura Uribe-Figueroa, Agnes Fleury, Edda Sciutto

“…SLAMF1 gene was downregulated in NC patients with extraparenchymal cysticerci, exhibiting higher inflammation levels than patients with parenchymal parasites. …”
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Association between white blood cell count and coronary artery bypass graft failure: an individual patient data analysis of clinical trials by Kevin R. An, Sigrid Sandner, Joyce Peper, Yanzai Zhou, Jurrien M. ten Berg, Lamia Harik, Yunpeng Zhu, Laura M. Willemsen, Qiang Zhao, Björn Redfors, Subodh Verma, Mario F. L. Gaudino

“…Abstract Background Baseline systemic inflammation is associated with worse long-term outcomes after coronary artery bypass grafting [CABG], but the mechanisms of this association are unclear. …”
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Autologous precision-cut lung slice co-culture models for studying macrophage-driven fibrosis by So-Yi Chang, So-Yi Chang, Wen-Hsin Chang, Wen-Hsin Chang, David C. Yang, Qi-Sheng Hong, Qi-Sheng Hong, Ssu-Wei Hsu, Ssu-Wei Hsu, Reen Wu, Ching-Hsien Chen, Ching-Hsien Chen

“…Precision-cut lung slices (PCLS) are commonly used as an ex vivo model to study lung fibrosis; however, traditional models lack immune cell infiltration, including the recruitment of monocytes and macrophages, which are critical for inflammation and fibrosis. To address this limitation, we developed novel autologous PCLS-immune co-culture models that better replicate the processes of inflammation, repair, and immune cell recruitment associated with fibrosis. …”
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Potential Involvement of IL-17F in Asthma by Kyoko Ota, Mio Kawaguchi, Satoshi Matsukura, Masatsugu Kurokawa, Fumio Kokubu, Junichi Fujita, Yuko Morishima, Shau-Ku Huang, Yukio Ishii, Hiroaki Satoh, Nobuyuki Hizawa

“…Several studies have demonstrated that IL-17F plays a pivotal role in allergic airway inflammation and induces several asthma-related molecules such as CCL20. …”
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Phytochemical investigation and assessment of the anti-inflammatory activity of four Heracleum taxa growing in Turkey by Ekin Kurtul, Esra Küpeli Akkol, Büşra Karpuz Ağören, Büşra Yaylacı, Özlem Bahadır Acıkara, Eduardo Sobarzo-Sánchez, Eduardo Sobarzo-Sánchez

“…Further investigations are necessary to identify the active compounds and elucidate the mechanisms of action of these plants, potentially leading to the discovery of novel therapeutic options for the treatment of inflammation.…”
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Assessment of Clinical Analgesic Levels and Serum Biomarkers in Patients with Rheumatoid Arthritis: A Randomized Controlled Trial Comparing the Efficacy of Diclofenac and Methotrex... by Mei Zhang, Zhongyuan Ma, Rinkiko Suguro, Menglin Zhu, Esther Xinyi Chen, Xin Dong, Meixiu Chen, Linling Cheng, Bolun Su, Yizhun Zhu

“…Patients who displayed pain control and stability were advised to continue the treatment, whereas those who had inflammation and discomfort were administered specific medications, and their progress was closely monitored until day 28. …”
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The importance of stem cells in the treatment of type 1 diabetes, type 2 diabetes and diabetes complications by Monika Kamińska, Maria Jasiewicz, Magdalena Miernik-Skrzypczak, Aleksandra Spyra, Marta Malicka, Natalia Dąbrowska, Aleksandra Kozioł, Katarzyna Moczyróg

“…For type 1 diabetes, MSCs reduced inflammation, preserved pancreatic islet function, and decreased insulin requirements without major adverse effects. …”
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Novel full-thickness biomimetic corneal model for studying pathogenesis and treatment of diabetic keratopathy by Zekai Cui, Xiaoxue Li, Yiwen Ou, Xihao Sun, Jianing Gu, Chengcheng Ding, Zhexiong Yu, Yonglong Guo, Yuqin Liang, Shengru Mao, Jacey Hongjie Ma, Hon Fai Chan, Shibo Tang, Jiansu Chen

“…LBGP promoted nerve regeneration, alleviated inflammation and oxidative stress in both in vitro and in vivo models. …”
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Injected Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Functional Muscle Regeneration after Trauma by Deana Haralampieva, Souzan Salemi, Thomas Betzel, Ivana Dinulovic, Stefanie D. Krämer, Roger Schibli, Tullio Sulser, Christoph Handschin, Simon M. Ametamey, Daniel Eberli

“…After muscle harvesting, inflammation levels were in parallel to radiotracer uptake amount, with significantly lower uptake in hPGC-1α overexpressing samples. …”
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Diabetic Ephrin-B2-Stimulated Peripheral Blood Mononuclear Cells Enhance Poststroke Recovery in Mice by Rose Hilal, Marine Poittevin, Adrien Pasteur-Rousseau, Adrien Cogo, Gabrielle Mangin, Marie Chevauché, Yasmine Ziat, José Vilar, Jean-Marie Launay, Jean-François Gautier, Dong Broquères-You, Bernard I. Levy, Tatyana Merkulova-Rainon, Nathalie Kubis

“…Infarct volume, neurological deficit, neurogenesis, angiogenesis, and inflammation were investigated as were the potential mechanisms of PB-MNC+ cells in poststroke neurorepair. …”
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A Network Pharmacology-Based Strategy for Unveiling the Mechanisms of Tripterygium Wilfordii Hook F against Diabetic Kidney Disease by Yuyang Wang, Tongtong Liu, Fang Ma, Xiaoguang Lu, Huimin Mao, Weie Zhou, Liping Yang, Ping Li, Yongli Zhan

“…The key mechanisms of TwHF against DKD might be involved in the reduction of renal inflammation by downregulating VEGFA.…”
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Clinical and Immunological Characteristics of Elderly Onset Rheumatoid Arthritis by LI Zhengfang, WU Chanyuan, MA Mengsi, LI Tingting, WU Xue, MENG Xinyan, ZHANG Sha, WU Lijun

“…EORA is prone to interstitial lung disease, anemia and high inflammation, and the level of peripheral blood NK cells is higher.…”
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