Gut-Lung Microbiota in Chronic Pulmonary Diseases: Evolution, Pathogenesis, and Therapeutics by Chang Yi Shi, Chen Huan Yu, Wen Ying Yu, Hua Zhong Ying

“…The imbalance of microbiota is usually linked to the aberrant immune responses and inflammation, which eventually promotes the occurrence and development of respiratory diseases. …”
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Examining the epigenetic transmission of risk for chronic pain associated with paternal post-traumatic stress disorder: a focus on veteran populations by James Freeman, Sabrina Salberg, Melanie Noel, Richelle Mychasiuk

“…Hence, epigenetic changes related to pain perception, inflammation, and neurotransmission may influence an individual’s predisposition to chronic pain conditions. …”
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CTRP9 Mitigates the Progression of Arteriovenous Shunt-Induced Pulmonary Artery Hypertension in Rats by Hua Guan, Xiaofeng Yang, Tao Shi, Yongjian Zhang, Aoqi Xiang, Yongxin Li

“…CTRP9 attenuated the pulmonary vascular remodeling in the shunt group by decreasing the mPAP and RVSP, which was associated with suppressed inflammation, apoptosis, and extracellular matrix injury. …”
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Critical Appraisal of Pharmaceutical Therapy in Diabetic Cardiomyopathy—Challenges and Prospectives by Elina Khattab, Michaelia Kyriakou, Elena Leonidou, Stefanos Sokratous, Angeliki Mouzarou, Michael M. Myrianthefs, Nikolaos P. E. Kadoglou

“…., glycation products), oxidative stress, low-grade inflammation, mitochondrial dysfunction, etc., which should guide the development of new therapeutic strategies. …”
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Nutritional and Pharmacological Effects on Oxidative Stress in Soft Tissue and Bone Remodeling by Benjamin M. Savasky, David P. Mascotti, Naren Patel, Edgardo Rodriguez-Collazo

“…We provide a review of the current literature of how oxidative damage and inflammation are linked to bone damage, Charcot neuroarthropathy, delayed wound healing, diabetic complications, and delayed flap consolidation. …”
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Targeting the B-Cell Pathway in Lupus Nephritis: Current Evidence and Future Perspectives by Panagiotis Pateinakis, Athina Pyrpasopoulou

“…Several hypotheses are currently experimentally tested to further elucidate the direct induction of inflammation through interaction of the pathological autoantibodies with intrinsic glomerular components and the triggering of a complement-driven autoinflammatory cascade. …”
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Helicobacter pylori-Induced Chronic Gastritis and Assessing Risks for Gastric Cancer by Gonzalo Carrasco, Alejandro H. Corvalan

“…Chronic gastritis is an inflammation of the gastric mucosa and has multiple etiologies. …”
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Potential therapeutic effect of thymoquinone on cisplatin-induced hepatotoxicity in rats by Sercan Kaya, Tuba Yalcin

“…<p> <b>Results: </b>CIS application increased liver enzyme levels, histopathological changes, inflammation, oxidative stress and apoptosis in liver tissue and caused a decrease in OTULIN level. …”
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ANCA-Associated Vasculitides and Hematologic Malignancies: Lessons from the Past and Future Perspectives by Marco Folci, Giacomo Ramponi, Dana Shiffer, Aurora Zumbo, Michele Agosti, Enrico Brunetta

“…Furthermore, the pathogenesis of ANCA-associated vasculitis has been reviewed with particular emphasis on the role of proteinase 3 (PR3) in fuelling granulomatosis with polyangiitis (GPA) inflammation. PR3 is a bactericidal protein expressed by neutrophilic granules and on their plasma membrane. …”
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GSK-3𝜷: A Bifunctional Role in Cell Death Pathways by Keith M. Jacobs, Sandeep R. Bhave, Daniel J. Ferraro, Jerry J. Jaboin, Dennis E. Hallahan, Dinesh Thotala

“…Secondary to the role of GSK-3β in various diseases including Alzheimer’s disease, inflammation, diabetes, and cancer, small molecule inhibitors of GSK-3β are gaining significant attention. …”
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Potential Role of the Inflammasome-Derived Inflammatory Cytokines in Pulmonary Fibrosis by Rupa Biswas, Melisa Bunderson-Schelvan, Andrij Holian

“…However, recent progress in inflammasome research has greatly contributed to our understanding of its role in inflammation and fibrosis development. The inflammasome is a multiprotein complex that is an important component of both the innate and adaptive immune systems. …”
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The Role of the Immune System in Huntington’s Disease by Gisa Ellrichmann, Christiane Reick, Carsten Saft, Ralf A. Linker

“…Further understanding the influence of inflammation in HD using mouse models may open various avenues for promising therapeutic approaches aiming at slowing disease progression or forestalling onset of disease.…”
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Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options by Ye. A. Poluektova, S. Yu. Kuchumova, O. S. Shifrin, A. A. Sheptulin, V. T. Ivashkin

“…In the last years more and more data appear on changes in qualitative and quantitative spectrum of intestinal microflora in combination to low degree inflammation of colonic mucosa at IBS that allowed to reconsider standard concepts on pathogenesis of this functional disorder. …”
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Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders? by Kristina Harris, Amira Kassis, Geneviève Major, Chieh J. Chou

“…., lipopolysaccharide) resulting in inflammation and (2) bacterial metabolites of dietary compounds (e.g., SCFA from fiber), which have biological activities that regulate host functions. …”
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Sterile osteomyelitis: a cardinal sign of autoinflammation by Tiago Borges, João Santos, Sérgio Silva

“…Autoinflammatory bone disorders (ABDs) are characterized by sterile bone inflammation stemming from dysregulated innate immune responses. …”
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Janus kinase inhibitors and biologics for treatment of livedoid vasculopathy: a systematic review by Yu Liu, Tingting Li, Wei Shi

“…Purpose: Livedoid vasculopathy (LV) is a chronic microvascular thrombosis disorder with an unclear pathogenesis, potentially involving hypercoagulability and inflammation. This systematic review aims to evaluate the efficacy and safety of Janus kinase (JAK) inhibitors and biologics in the treatment of LV.Materials and methods: A comprehensive search was conducted in PubMed, EMBASE, and the Cochrane Library on June 10, 2024, to identify relevant studies evaluating the use of JAK inhibitors and biologics in LV treatment.Results: A total of 15 articles were included in the review. …”
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Hsp70 and Its Molecular Role in Nervous System Diseases by Giuseppina Turturici, Gabriella Sconzo, Fabiana Geraci

“…Hsp70 functions as a chaperone and protects neurons from protein aggregation and toxicity (Parkinson disease, Alzheimer disease, polyglutamine diseases, and amyotrophic lateral sclerosis), protects cells from apoptosis (Parkinson disease), is a stress marker (temporal lobe epilepsy), protects cells from inflammation (cerebral ischemic injury), has an adjuvant role in antigen presentation and is involved in the immune response in autoimmune disease (multiple sclerosis). …”
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Lupus Enteritis as an Initial Presentation of Systemic Lupus Erythematosus by Sisira Sran, Manpreet Sran, Narmisha Patel, Prachi Anand

“…Lupus enteritis is a distinct subset of SLE, defined as either vasculitis or inflammation of the small bowel, with supportive image and/or biopsy findings. …”
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Chronic active lesions in multiple sclerosis: classification, terminology, and clinical significance by Assunta Dal-Bianco, Jiwon Oh, Pascal Sati, Martina Absinta

“…In multiple sclerosis (MS), increasing disability is considered to occur due to persistent, chronic inflammation trapped within the central nervous system (CNS). …”
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Retropharyngeal Calcific Tendinitis Mimicking a Retropharyngeal Phlegmon by Nathalie Gabra, Manon Belair, Tareck Ayad

“…It was first described by Hartley in 1964 as an inflammation of the longus colli muscle secondary to calcium crystals deposition on its insertion. …”
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