Blastomycosis Presenting as Multiple Splenic Abscesses: Case Report and Review of the Literature by Sami Al-Nassar, Tracy MacNair, Jeremy Lipschitz, Howard Greenberg, Elly Trepman, Sate Hamza, John M Embil

“…Computed tomographic-guided needle biopsy showed necrotizing granulomatous inflammation and multinucleated giant cells. Gomori’s methenamine silver stain showed broad-based budding yeast consistent with Blastomyces dermatitidis. …”
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Navigating the Role and Approach of Gut Microbiota in Addressing Alzheimer's Disease Pathogenesis by Imrana Jazuli, Akeela Jazeel, Lakshmi Selvaratnam, Deepa Alex, Yatinesh Kumari

“…Dysregulation of microbiota taxa can trigger systemic inflammation by increasing gut permeability, ultimately leading to neural damage and neurodegeneration. …”
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Prediction of IL4 Inducing Peptides by Sandeep Kumar Dhanda, Sudheer Gupta, Pooja Vir, G. P. S. Raghava

“…It has a critical role in guiding antibody class switching, hematopoiesis and inflammation, and the development of appropriate effector T-cell responses. …”
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A Rare Case of Melanosis of the Hard Palate Mucosa in a Patient with Chronic Myeloid Leukemia by Umberto Romeo, Gaspare Palaia, Paolo Junior Fantozzi, Gianluca Tenore, Daniela Bosco

“…There was no sign of inflammation, hyperplasia, or hemorrhage in the tissue.…”
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TLR10 overexpression modulates immune response in A549 lung epithelial cells challenged with SARS-CoV-2 S and N proteins by Špela Knez, Mojca Narat, Jernej Ogorevc

“…Modulation of TLR10 expression could have implications for the treatment of patients with severe COVID-19, in whom excessive inflammation leading to the development of acute respiratory distress syndrome (ARDS) is a key feature. …”
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Corrigendum: The role of dendritic cells in tertiary lymphoid structures: implications in cancer and autoimmune diseases by Mariana Reste, Kristi Ajazi, Ayca Sayi-Yazgan, Ayca Sayi-Yazgan, Radmila Jankovic, Biljana Bufan, Sven Brandau, Espen S. Bækkevold, Florent Petitprez, Malin Lindstedt, Gosse J. Adema, Catarina R. Almeida

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Biological Activity and Taxonomy of Persea americana Mill: A Systematic Review by Abdulrahman Mahmoud Dogara

“…In the 113 articles published, it was discovered that the plant extract worked well against cancer, free radicals, bacteria, parasites, inflammation, and diabetes. The chemical compound that was mentioned the most frequently was polyphenol. …”
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Clinical and Diagnostic Considerations for Atypical, Adult Onset Presentation of Chronic Recurrent Multifocal Osteomyelitis (CRMO) by Stacey Mahady, Amit Ladani

“…Bone biopsy histologic results of marrow fibrosis and plasma cell infiltrate indicative of chronic inflammation lead to the diagnosis of CRMO. This case highlights that while CRMO is typically a disease with childhood onset, it, while rare, can also present in adults and now has presented in the elderly, remaining an important part of the differential diagnosis of bone pain in adults and the elderly in addition to infectious osteomyelitis and malignancy when imaging reveals multiple bony lesions. …”
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Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery by Hans-Erik Johansson, Arvo Haenni, Björn Zethelius

“…Roux-en-Y gastric bypass (RYGBP) is an established method for treatment of obesity, a condition of chronic inflammation with liver steatosis, characterised by increased erythrocyte sedimentation rate (ESR), white blood cell count (WBC), liver enzymes, and decreased magnesium (Mg). …”
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Infectious scleritis: a review of etiologies, clinical features, and management strategies by Supriya Sharma, Jay U. Sheth, Somasheila I. Murthy, Somasheila I. Murthy

“…Infectious scleritis is a severe and potentially vision-threatening inflammation of the sclera caused by microbial invasion. …”
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An Overview on Dry Eye Treatment: Approaches for Cyclosporin A Delivery by Burçin Yavuz, Sibel Bozdağ Pehlivan, Nurşen Ünlü

“…Changes in tear composition also promote inflammation on the ocular surface by various mechanisms. …”
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Giant Cell Myocarditis in a Patient With Crohn's Disease, Treated with Etanercept – A Tumour Necrosis Factor-Alpha Antagonist by C Nash, R Panaccione, LR Sutherland, JB Meddings

“…Reports include pericarditis, pericardial effusion, myocarditis, myocardial infarction, endocarditis and arrythmias. Myocardial inflammation related to IBD may be due to a drug hypersensitivity reaction or micronutrient deficiency, or may be secondary to the underlying IBD as an extraintestinal manifestation. …”
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PPAR Agonists and Cardiovascular Disease in Diabetes by Anna C. Calkin, Merlin C. Thomas

“…However, data from murine models suggests that PPAR agonists also have independent anti-atherosclerotic actions, including the suppression of vascular inflammation, oxidative stress, and activation of the renin angiotensin system. …”
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Moving from an “anti-aging” paradigm toward the concept of “disease-free aging”: the role of senolytics in modern medicine by Ivan Aprahamian, Andréia Pain, Virgílio Garcia Moreira

“…Senescent cells increase with aging and are related to the promotion of inflammation and neoplasia through the senescence-associated secretory phenotype (SASP). …”
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The role of immunity in insulin resistance in patients with polycystic ovary syndrome by Qixuan Zhang, Zhe Yang, Xiangyang Ou, Mengying Zhang, Xiangyu Qin, Gengxiang Wu

“…Therefore, this review aims to elucidate the interplay between IR in PCOS patients, the controlled immune response orchestrated by immune cells and immunomodulatory molecules, and their interactions with adipocytes, hyperandrogenemia, chronic inflammation, and metabolic homeostasis.…”
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Emerging Therapeutic Strategies for Limbal Stem Cell Deficiency by Ying Dong, Han Peng, Robert M. Lavker

“…LSCD is characterized by an overgrowth of conjunctival-derived epithelial cells, corneal neovascularization, and chronic inflammation, eventually leading to blindness. Treatment of LSCD has been challenging, especially in bilateral total LSCD. …”
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KIF26B and CREB3L1 Derived from Immunoscore Could Inhibit the Progression of Ovarian Cancer by Shanshan Cong, Yao Fu, Xibo Zhao, Qiuyan Guo, Tian Liang, Di Wu, Jing Wang, Guangmei Zhang

“…The local infection or inflammation of ovarian may affect the immunity of OV. …”
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Eumisetoma pada Toraks dan Abdomen: Suatu Kasus Jarang by Jimy Fran, Istiana Fiatiningsih, Ilhami Romus

“…Histopathological examination of hematoxylin-eosin showed suppurative granulomatous inflammation consisting of epitheloid histiocytes, solid lymphocytes and neutrophils, and datia cells. …”
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Successful Modified Therapy in a Patient with Probable Infection-Associated Hemophagocytic Lymphohistiocytosis by Carl L. Kay, Matthew J. Rendo, Paul Gonzales, Sead G. Beganovic, Magdalena Czader

“…Hemophagocytic lymphohistiocytosis (HLH) is a rare, hyperinflammatory syndrome characterized by clinical signs and symptoms of extreme inflammation. In adults, HLH is typically a complication of infections, autoimmune diseases, and malignancies. …”
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Severe Case of Chronic Pelvic Pain Syndrome: Recovery after Injection of Procaine into the Vesicoprostatic Plexus—Case Report and Discussion of Pathophysiology and Mechanisms of Ac... by R. M. Kronenberg, S. M. Ludin, L. Fischer

“…A possible explanation may be that the positive feedback loops maintaining pain and neurogenic inflammation are disrupted by LA infiltration. This can lead to a new organisation (self-organisation) of the pain-processing systems.…”
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