Showing 481 - 500 results of 8,229 for search '"inflammation"', query time: 0.08s Refine Results
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    Pathological Roles of Neutrophil-Mediated Inflammation in Asthma and Its Potential for Therapy as a Target by Han Gao, Songmin Ying, Yuanrong Dai

    Published 2017-01-01
    “…It has commonly been considered that airway inflammation is caused by the Th2 immune response, or eosinophilia, which is a hallmark of bronchial asthma pathogenesis. …”
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  3. 483

    Quantitative and longitudinal assessment of human placental inflammation using diffusion basis spectrum imaging by Zhexian Sun, Wenjie Wu, Zezhen Xiang, Hansong Gao, Weina Ju, Cherilyn Uhm, Ian S. Hagemann, Pamela K. Woodard, Nanbert Zhong, Alison G. Cahill, Qing Wang, Yong Wang

    Published 2025-01-01
    “…We validated placental DBSI in simulations and ex-vivo specimens, then applied it to 202 MRI scans from 82 patients whose placentas were classified as non-inflammation (n = 70) or inflammation (n = 12). Our method imaged the 3D distribution of immune cells, revealing significantly greater infiltration in the inflammation placentas from early (2.8% ± 0.7% vs. 4.8% ± 0.65%, p < 0.01) to late pregnancy (4.75% ± 0.9% vs. 7.25% ± 2.13%, p < 0.01). …”
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    Tanshinone I Ameliorates Psoriasis-Like Dermatitis by Suppressing Inflammation and Regulating Keratinocyte Differentiation by Wang Q, Luo X, Su Y, Jin Y, Kuang Q, Li S, Shen W, Zhu Y

    Published 2025-01-01
    “…Additionally, Tan-I restored keratin expression patterns, increasing K1 and decreasing K6 and K17 levels in both mouse skin and HaCaT cells.Conclusion: Tan-I is a promising therapeutic candidate for psoriasis, effectively mitigating inflammation, normalizing keratinocyte differentiation, and inhibiting abnormal keratinocyte apoptosis.Keywords: psoriasis, tanshinone I, immune modulation, keratinocyte, apoptosis…”
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    Inflamm-Aging-Related Cytokines of IL-17 and IFN-γ Accelerate Osteoclastogenesis and Periodontal Destruction by Jingyi Tan, Anna Dai, Lai Pan, Lan Zhang, Zhongxiu Wang, Ting Ke, Weilian Sun, Yanmin Wu, Pei-Hui Ding, Lili Chen

    Published 2021-01-01
    “…Periodontal disease (PD), as an age-related disease, prevalent in middle-aged and elderly population, is characterized as inflammatory periodontal tissue loss, including gingival inflammation and alveolar bone resorption. However, the definite mechanism of aging-related inflammation in PD pathology needs further investigation. …”
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    Disruption in the Blood-Brain Barrier: The Missing Link between Brain and Body Inflammation in Bipolar Disorder? by Jay P. Patel, Benicio N. Frey

    Published 2015-01-01
    “…Considering the increasing role of inflammation and oxidative stress in the pathophysiology of bipolar disorder (BD), here we propose a novel model wherein transient or persistent disruption of BBB integrity is associated with decreased CNS protection and increased permeability of proinflammatory (e.g., cytokines, reactive oxygen species) substances from the peripheral blood into the brain. …”
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