Peroxisome Proliferator-Activated Receptor γ and PGC-1α in Cancer: Dual Actions as Tumor Promoter and Suppressor by Seong-Hoon Yun, Sang-Heum Han, Joo-In Park

“…Peroxisome proliferator-activated receptor γ (PPARγ) is part of a nuclear receptor superfamily that regulates gene expression involved in cell differentiation, proliferation, immune/inflammation response, and lipid metabolism. PPARγ coactivator-1α (PGC-1α), initially identified as a PPARγ-interacting protein, is an important regulator of diverse metabolic pathways, such as oxidative metabolism and energy homeostasis. …”
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An Unusual Case of Gastrointestinal Bleeding from Isolated Gallbladder Varices in a Patient with Pancreatic Cancer Complicated by Portal Biliopathy by Mahir Gachabayov, Kubach Kubachev, Elbrus Abdullaev, Nonna Zarkua, Abakar Abdullaev, Artur Fokin

“…Portal biliopathy is the complex of abnormalities of extrahepatic and intrahepatic bile ducts, cystic duct, and gallbladder, arising as a result of extrahepatic portal vein obstruction and noncirrhotic portal fibrosis, which can be caused by coagulopathies, tumors, inflammation, postoperative complications, dehydration, and neonatal umbilical vein catheterization. …”
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Opening a Window on Attention: Adjuvant Therapies for Inflammatory Bowel Disease by Qiyue Wang, Shuyi Mi, Zixuan Yu, Qiyi Li, Jiacai Lei

“…This review focuses on different ancillary therapies for IBD treatments, in particular the mechanism of reducing inflammation based on the actual data from research studies. …”
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Complement Activation and Inhibition in Wound Healing by Gwendolyn Cazander, Gerrolt N. Jukema, Peter H. Nibbering

“…Complement activation is needed to restore tissue injury; however, inappropriate activation of complement, as seen in chronic wounds can cause cell death and enhance inflammation, thus contributing to further injury and impaired wound healing. …”
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New Possibilities for the Treatment of Crohn’s Disease by Z. A. Mamieva, E. A. Poluektova, O. S. Shifrin

“…The drug interrupts the cascade of humoral and cellular reactions leading to transmural inflammation of the intestinal wall by blocking the interaction of the p40 subunit with the IL-12Rβ1 chain on the surface of T-lymphocytes and NK cells. …”
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Silicosis: from pathogenesis to therapeutics by Bijun Yang, Xiaoman Liu, Cheng Peng, Xiangjing Meng, Qiang Jia

“…The main pathological process involves parenchymal lung injury, inflammation and lung tissue fibrosis, but the exact pathogenesis remains elusive. …”
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A Study of Factors Contributing to Denture Stomatitis in a North Indian Community by Amit Vinayak Naik, Ranjana C. Pai

“…Denture age was proportional to Candida colonization and not to degree of inflammation. Significant differences were found in Candida colonization of the fitting surface of the denture between stomatitis and control groups. …”
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Exosome-Derived microRNA: Potential Target for Diagnosis and Treatment of Sepsis by Yujie Xiao, Yixuan Yuan, Dahai Hu, Hongtao Wang

“…This review comprehensively explores the biology of exosome-derived miRNAs, which originate from both immune cells (such as macrophages and dendritic cells) and nonimmune cells (such as endothelial and epithelial cells) and play a dynamic role in modulating pathways that affect the course of sepsis, including those related to inflammation, immune response, cell survival, and apoptosis. …”
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Limbal Pseudoepitheliomatous Hyperplasia Mimicking Ocular Surface Squamous Neoplasia in Palpebral Vernal Keratoconjunctivitis by Chintan Malhotra, Arun K. Jain, Bikram Thapa

“…The subepithelium revealed a dense plasma-rich inflammation. Discussion. We report this relatively uncommon presentation of limbal pseudoepitheliomatous hyperplasia mimicking an ocular surface squamous neoplasia in palpebral vernal keratoconjunctivitis. …”
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Myokines as Possible Therapeutic Targets in Cancer Cachexia by Emilia Manole, Laura C. Ceafalan, Bogdan O. Popescu, Carmen Dumitru, Alexandra E. Bastian

“…Cachexia is an extremely serious syndrome which occurs in most patients with different cancers, and it is characterized by systemic inflammation, a negative protein and energy balance, and involuntary loss of body mass. …”
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Cutaneous Disease as Sole Clinical Manifestation of Protothecosis in a Boxer Dog by Emmanouil I. Papadogiannakis, Emmanouil N. Velonakis, Gregory K. Spanakos, Alexander F. Koutinas

“…Cytology and histopathology showed pyogranulomatous inflammation along with organisms containing round sporangia with spherical sporangiospores. …”
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In Vivo Exposure of Deltamethrin Dysregulates the NFAT Signalling Pathway and Induces Lung Damage by Prakriti Sharma, R. S. Sethi

“…Long-term exposure to deltamethrin results in the inflammation of the lungs. The present study elucidates the molecular mechanism underlying the deltamethrin-induced lung damage. …”
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Candidates for Bariatric Surgery: Morbidly Obese Patients with Pulmonary Dysfunction by Yu-Feng Wei, Huey-Dong Wu

“…Effective weight loss after bariatric surgery may improve cardiovascular disease risk factors, including diabetes, hypertension, dyslipidemia, atherosclerosis, inflammation, chronic kidney disease, obstructive sleep apnea, and obesity hypoventilation syndrome. …”
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Abdominal Wall Defects: Hydrogel based solutions in Abdominal Wall Reconstruction by Alook Kumar Ajay, Shashi Ranjan, Rajendra Singh, Shalini Kapoor Mehta

“…This paper explores the design and application of these hydrogels, highlighting their potential to improve surgical outcomes through enhanced tissue integration, reduced inflammation, and minimized postoperative complications. …”
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Repository Corticotropin Injection for Treatment of Idiopathic Inflammatory Myopathies by Aarat Patel, Georgia Seely, Rohit Aggarwal

“…Idiopathic inflammatory myopathies are a group of systemic autoimmune diseases that involve inflammation of skeletal muscle. The two most common forms are dermatomyositis and polymyositis, the former of which entails a skin component. …”
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Low-Dose Gallic Acid Administration Does Not Improve Diet-Induced Metabolic Disorders and Atherosclerosis in Apoe Knockout Mice by Jie Bai, Qiu-Yue Lin, Xiangbo An, Shuang Liu, Yao Wang, Yunpeng Xie, Jiawei Liao

“…Gallic acid (GA) is a plant-derived triphenolic chemical with multiple cardio-protective properties, such as antiobesity, anti-inflammation, and antioxidation. However, whether GA could protect against atherosclerotic cardiovascular diseases is still not defined. …”
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A Challenging Diagnosis of Ascites: A Case Report of Peritoneal Tuberculosis by Jose Ruiz, Maedeh Ganji, Catarina Canha, Carmen Isache

“…He underwent omental biopsy which showed necrotizing granulomatous inflammation with rare acid-fast bacilli. Repeat biopsy was culture positive for mycobacterium tuberculosis complex. …”
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Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis by David Qixiang Chen, José Adalberto Inzunza Domínguez, Juan Manuel Valle Uzeta, Abhiram P. Pushparaj, Abhiram P. Pushparaj, Jonathan E. Dickinson

“…Patient A demonstrated substantial lesion shrinkage and decreased Apparent Diffusion Coefficient (ADC) values, suggesting remyelination and reduced inflammation. Both patients exhibited cortical and subcortical alterations, particularly in regions associated with pain and emotional processing. …”
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NF-κB signaling and the tumor microenvironment in osteosarcoma: implications for immune evasion and therapeutic resistance by Shaoyan Shi, Xuehai Ou, Chao Liu, Rui Li, Qianjin Zheng, Leiming Hu

“…It also enhances tumor cell resistance to chemotherapy and radiotherapy by activating anti-apoptotic signaling pathways and exacerbating treatment-induced inflammation. Potential therapeutic approaches include using NF-κB inhibitors, possibly in combination with immune checkpoint inhibitors, to overcome tumor cell resistance mechanisms and reshape antitumor immune responses. …”
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Lupus Pneumonitis Therapy Masks Coronavirus (COVID-19) by S. Soloway, N. L. DePace, A. M. Soloway, J. Colombo

“…Coronavirus pneumonitis can mimic, or present as, lupus pneumonitis. Lupus may cause inflammation of the myocardium. Lupus pneumonitis high-dose steroid therapy may mask coronavirus (COVID-19). …”
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