Ocular Complications of Inflammatory Bowel Disease by Rana Mady, Will Grover, Salim Butrus

“…Primary complications are usually temporally associated with IBD exacerbations and tend to resolve with systemic treatment of the intestinal inflammation. These include keratopathy, episcleritis, and scleritis. …”
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Cardiovascular Disease Risk Factors in the Native American Population by Krista Goerger, Karla Abbott, Mark K. Larson, Michael Holinstat

“…Chronic activation of stress responses through the hypothalamic–pituitary–adrenal and autonomic nervous system increases inflammation and cardiovascular dysfunction resulting in an increased risk for cardiovascular disease. …”
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Irritable Bowel and Bacterial Overgrowth Syndromes: a Bacterial Link Hypothesis of Functional Disease by K. V. Ivashkin, V. R. Grechishnikova, M. S. Reshetova, V. T. Ivashkin

“…SIBO may represent a "peripheral" mechanism of IBS, aside to nonspecific inflammation, increased epithelial permeability and local immune system activation. …”
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Focal Xanthogranulomatous Pyelonephritis with Pulmonary Lesions on the Background of Type Two Diabetes Mellitus by Ahmad Enshaei, Arash A. Boora, Diana Taheri, Zahra Changizi, Nahid Bahmani

“…Focal Xanthogranulomatous pyelonephritis is a rare chronic inflammatory condition of kidneys which usually is associated with postrenal obstruction or renal stone leading to chronic bacterial infection and eventually chronic glomerular inflammation. About 90% of cases are of the diffuse type and associated with staghorn renal calculi. …”
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Annexin A5–Functionalized Nanoparticle for Multimodal Imaging of Cell Death by Rui Zhang, Miao Huang, Min Zhou, Xiaoxia Wen, Qian Huang, Chun Li

“…Three different models were conducted, including tumor apoptosis, hepatic apoptosis, and inflammation. Both micro single-photon emission tomography/computed tomography (μSPECT/CT) and fluorescence molecular tomography (FMT) were performed. …”
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Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology by Olvera-Montaño Cecilia, Castellanos-González José Alberto, Navarro-Partida José, Cardona-Muñoz Ernesto Germán, López-Contreras Ana Karen, Roman-Pintos Luis Miguel, Robles-Rivera Ricardo Raúl, Rodríguez-Carrizalez Adolfo Daniel

“…There are numerous mechanisms involved in its development such as inflammation and cellular degeneration leading to endothelial and neural damage. …”
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Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia by Nura El-Haj, Wilson I. Gonsalves, Vinay Gupta, Jacob P. Smeltzer, Sameer A. Parikh, Preet P. Singh, Naseema Gangat

“…It results in excessive inflammation and tissue destruction. Prompt initiation of treatment is warranted in either scenario in order to decrease mortality. …”
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Orthotic treatment of hip dislocation derived from femoral neck osteomyelitis. Two cases report by José Julio Requeiro Molina, Ana María Machado Consuegra, Liyanira Alonso Leiva, Juana María Morejón Fernández, Gabriela María Requeiro Molina, José Julio Requeiro Morejón

“…Osteomyelitis is a bone inflammation caused mainly by bacteria. In cases of the femur’s neck osteomyelitis and concomitant septic arthritis, complications can lead to considerable joint shortening and deterioration in the long term. …”
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Arsenic Trioxide in Synergy with Vitamin D Rescues the Defective VDR-PPAR-γ Functional Module of Autophagy in Rheumatoid Arthritis by Weiyan Wang, Chunling Li, Zhiyi Zhang, Yue Zhang

“…ATO alleviated RA symptoms by boosting effective autophagic flux through significantly downregulating p62, the inflammation and catabolism protein. Importantly, low-dose ATO synergizes with Vitamin D in RA treatment.…”
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Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells by Sara Sprangers, Teun J. de Vries, Vincent Everts

“…Although monocytes maintain several tissue-specific populations of immune cells in homeostasis, their contribution to populations of dendritic cells, macrophages, and osteoclasts is significantly increased in inflammation. Identification of a growing number of functionally different subsets of cells within populations of monocyte-derived immune cells has recently put monocyte heterogeneity into sharp focus. …”
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Non-invasive of liver fibrosis diagnostics: the role of serum markers by A. F. Sheptulina, Ye. N. Shirokova, V. T. Ivashkin

“…Investigations in the field of fibrogenesis processes made possible quantitative estimation of liver fibrosis by non-invasive tests based both on assessment of peripheral blood levels of substances, directly involved in various stages of extracellular matrix synthesis and disintegration, and on the routine laboratory tests reflecting activity of inflammation, degree of disorder of synthetic liver function and fibrosis progression.Conclusion. …”
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Emerging therapeutics in idiopathic inflammatory myopathy by Shinji Sato

“…Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of systemic autoimmune diseases characterized mainly by inflammation of muscle tissue. Although IIM traditionally encompasses polymyositis, dermatomyositis (DM), and inclusion body myositis, the disease concept has been changing in association with progress in diagnostic techniques. …”
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Relapsing Polychondritis in a Patient with Ankylosing Spondylitis Using Etanercept by Valderilio Feijó Azevedo, Natalia Bassalobre Galli, Alais Daiane Fadini Kleinfelder, Julia Farabolini D’Ippolito, Andressa Gulin Tolentino, Eduardo Paiva

“…Relapsing polychondritis (RP) is an autoimmune disease characterized by recurrent episodes of inflammation and progressive destruction of cartilaginous tissues, especially of the ears, nose, joints, and tracheobronchial tree. …”
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Probiotics in Depression Management: Efficacy, Mechanisms and Future Directions by Learn-Han Lee

“…The pathophysiology is often attributed to neurotransmitter imbalances, hypothalamic-pituitary-adrenal (HPA) axis dysfunction, and inflammation. Recently, the gut-brain axis has garnered attention for its role in mood regulation, suggesting that probiotic supplementation may influence depressive symptoms through gut microbiome modulation. …”
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Rare Case Studies of Bilateral and Symmetric Sacroiliac Disease by Stephen Soloway, Alyxandra M. Soloway, Tyler G. Chin, Timothy Lieske

“…Our goal is to point out the importance of proper evaluation, diagnosis, and importance of inflammatory SIJ disease and conditions that involve SIJ inflammation. Cases. We present three rare conditions presenting with bilateral and symmetric SIJ disease, none of which is ankylosing spondylitis, Crohn’s colitis, ulcerative colitis, psoriatic arthritis, and reactive arthritis (Reiter syndrome); there are reports of concurrent SIJ disease in rheumatoid arthritis and SLE. …”
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Beneficial Effects of Resveratrol-Mediated Inhibition of the mTOR Pathway in Spinal Cord Injury by Jingying Zhou, Xue Huo, Benson O. A. Botchway, Luyao Xu, Xiaofang Meng, Songou Zhang, Xuehong Liu

“…The mammalian target of rapamycin (mTOR) signaling pathway plays an important role in cell death and inflammation in the acute phase and neuroregeneration in the subacute/chronic phases at different times. …”
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A Patient with Double-Negative VGKC, Peripheral Nerve Hyperexcitability, and Central Nervous System Symptoms: A Postinfectious Autoimmune Disease by Birte Eikeland

“…Research in the last few years has indicated that most voltage-gated potassium channel- (VGKC-) complex antibodies without leucine-rich glioma-inactivated protein 1 or contactin-associated protein-like 2 antibody specificity lack pathogenic potential and are not clear markers for autoimmune inflammation. Here we report on a patient with double-negative VGKC who developed severe peripheral nerve hyperexcitability, central nervous system symptoms with agitation and insomnia, dysautonomia, and systemic symptoms with weight loss, itch, and skin lesions. …”
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Nonalcoholic Fatty Liver Disease and Sarcopenia: Where Do We Stand? by Ivana Mikolasevic, Tajana Pavic, Tajana Filipec Kanizaj, Darija Vranesic Bender, Viktor Domislovic, Zeljko Krznaric

“…Crucial mechanisms involved in sarcopenia-nonalcoholic fatty liver disease (NAFLD) interplay are based on effects of insulin resistance, chronic inflammation, oxidative stress, and crosstalk between organs by secretion of cytokines (hepatokines, adipokines, and myokines). …”
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A Paraneoplastic Syndrome Characterized by Extremity Swelling with Associated Inflammatory Infiltrate Heralds Aggressive Transformation of Myelodysplastic Syndromes/Myeloproliferat... by James K. Mangan, Selina M. Luger

“…In each case, the transformation to AML was preceded by an inflammatory syndrome characterized by unilateral extremity swelling and an associated inflammatory skin infiltrate, as well as other signs of inflammation, including profound hyperferritinemia without evidence of a hemophagocytic syndrome. …”
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Supraventricular Arrhythmias after Thoracotomy: Is There a Role for Autonomic Imbalance? by George Vretzakis, Marina Simeoforidou, Konstantinos Stamoulis, Metaxia Bareka

“…Investigators believe that surgical factors (irritation of the atria per se or on the ground of chronic inflammation of aged atria), direct injury to the anatomic structure of the autonomic nervous system in the thoracic cavity, and postthoracotomy pain may contribute independently or in association with each other to the development of these arrhythmias. …”
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