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4821
Family case of cardiac achalasia
Published 2014-10-01“…Cardiac achalasia is idiopathic disease, caused by inflammation and degeneration of myenteric plexus resulting in loss of postganglionic inhibitory neurons, essential for relaxation of the lower esophageal sphincter and peristaltic contractions of the esophagus. …”
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4822
The micro(nano)plastics perspective: exploring cancer development and therapy
Published 2025-01-01“…Microplastics are capable of triggering cytotoxicity and chronic inflammation, and may promote cancer through mechanisms such as pro-inflammatory responses, oxidative stress and endocrine disruption. …”
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4823
Cytokine landscapes of pregnancy: mapping gestational immune phases
Published 2024-04-01“…The article offers a detailed account of immune adaptations during pregnancy and highlights the distinctive cytokine profiles that mark each phase.Conclusion By providing a simplified depiction of pregnancy phases based on cytokine profiles, the article aims to inspire more research in reproductive immunology and improve the management of pregnancy-related inflammation and infection.…”
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4824
Genetically Engineered Islets and Alternative Sources of Insulin-Producing Cells for Treating Autoimmune Diabetes: Quo Vadis?
Published 2012-01-01“…However, two major problems need to be overcome: (1) detrimental immune responses, including inflammation induced by the islet isolation/transplantation procedure, recurrence autoimmunity, and allorejection, can cause graft loss and (2) inadequate numbers of organ donors. …”
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4825
Microbiome in development of esophageal diseases
Published 2016-08-01“…Toll-like receptors, cytokines, nuclear factor κB, cyclooxygenase-2 can be potential mediators of inflammation and carcinogenesis which expression can be modified by microbiome spectrum. …”
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4826
Exploring Marine Cyanobacteria for Lead Compounds of Pharmaceutical Importance
Published 2012-01-01“…Several of these compounds show pharmacological activities and are helpful for the invention and discovery of bioactive compounds, primarily for deadly diseases like cancer, acquired immunodeficiency syndrome (AIDS), arthritis, and so forth, while other compounds have been developed as analgesics or to treat inflammation, and so forth. They produce a large variety of bioactive compounds, including substances with anticancer and antiviral activity, UV protectants, specific inhibitors of enzymes, and potent hepatotoxins and neurotoxins. …”
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4827
Regulation of Glial Cell Functions by PPAR-𝜸 Natural and Synthetic Agonists
Published 2008-01-01“…In the present article, we will review the recent findings supporting a major role for PPAR-𝛾 agonists in controlling neuroinflammation and neurodegeneration through their activities on glial cells, with a particular emphasis on microglial cells as major macrophage population of the brain parenchyma and main actors in brain inflammation.…”
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4828
Pulsed Electromagnetic Field Therapy as a Complementary Alternative for Chronic Pelvic Pain Management in an Interstitial Cystitis/Bladder Pain Syndrome Patient
Published 2019-01-01“…Pulsed electromagnetic field therapy is a noninvasive therapeutic strategy that is thought to reduce inflammation and pain via alteration of cellular function and microcirculation. …”
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4829
Newly Diagnosed Colonic Adenocarcinoma: The Presenting Sign in a Young Woman with Undiagnosed Crohn’s Disease in the Absence of Primary Sclerosing Cholangitis and a Normal Microsat...
Published 2017-01-01“…The nonneoplastic grossly uninvolved background mucosa showed marked crypt distortion, crypt abscesses, CD-like lymphoid hyperplasia, transmural inflammation, and reactive epithelial atypia. Additional patient questioning revealed frequent loose stools since she was a teenager leading to diagnosis of a previously undiagnosed CD without primary sclerosing cholangitis (PSC). …”
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4830
Responsive nanomaterials in biomedicine, patent path and prospect analysis
Published 2025-02-01“…For complex diseases such as cancer, chronic inflammation, and genetic disorders, traditional treatment methods are often limited by insufficient targeting and significant side effects. …”
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4831
Oxidative stress in viral hepatitis
Published 2024-04-01“…This damage manifests as lipid peroxidation, DNA damage, and protein oxidation, which in turn promote hepatic inflammation, fibrosis, and hepatocellular carcinoma. …”
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4832
Management of a Dog with Poorly Regulated Diabetes Mellitus, Chronic Pancreatitis, and Suspected Atopy with Cyclosporine
Published 2012-01-01“…Pruritus improved and coincidentally serum Spec cPL and fructosamine concentrations normalized after therapy, suggesting the possibility that cyclosporine may have controlled pancreatic inflammation and improved control of diabetes mellitus. …”
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4833
Health aspects of peanuts as an outcome of its chemical composition
Published 2020-03-01“…Limited evidence also suggests beneficial effects on hypertension, cancer, and inflammation. The health risk associated with peanut consumption is allergy in developed countries. …”
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4834
Hepatoprotective Potential of Sargassum muticum against STZ-Induced Diabetic Liver Damage in Wistar Rats by Inhibiting Cytokines and the Apoptosis Pathway
Published 2019-01-01“…Liver inflammation and necrosis are the foremost problems interlinked with diabetes mellitus (DM). …”
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4835
Dietary content and eating behavior in ulcerative colitis: a narrative review and future perspective
Published 2025-01-01“…However, when this equilibrium is disturbed, a harmful cycle of dysbiosis, immune dysregulation, and inflammation emerges, resulting in intestinal barrier dysfunction and UC progression. …”
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4836
Recent Advances of the NLRP3 Inflammasome in Central Nervous System Disorders
Published 2016-01-01“…These cytokines play a critical role in mediating inflammation and innate immunity response. Among various inflammasome complexes, the NLRP3 inflammasome is the best characterized, which has been demonstrated as a crucial role in various diseases. …”
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4837
Saliva: Physiology and Diagnostic Potential in Health and Disease
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4838
The Role of T Helper (TH)17 Cells as a Double-Edged Sword in the Interplay of Infection and Autoimmunity with a Focus on Xenobiotic-Induced Immunomodulation
Published 2013-01-01“…In this context, heavy metals constitute a prominent category of xenobiotic substances, known to alter divergent immune cell responses in accidentally and occupationally exposed individuals, thereby increasing the susceptibility to autoimmunity and cancer, especially when accompanied by inflammation-triggered persistent sensitization. This perception is learned from experimental models of infection and epidemiologic studies and clearly underscores the interplay of exposure to such immunomodulatory elements with pre- or postexposure infectious events. …”
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4839
Biological therapy in the reduction of cardiovascular risk in patients with psoriasis
Published 2025-01-01“…They are attributed to persistent chronic inflammation, which is a common factor in both diseases. …”
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4840
An Unusual Case of Recurrent Hypersensitivity Reaction Associated with Kounis-Like Acute Coronary Syndrome
Published 2017-01-01“…We postulate that slow mediators of inflammation may play a role in delayed development of acute coronary events with associated LV dysfunction following episodes of angioedema and anaphylaxis.…”
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