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4801
Effects of Standardized Natural Citrus Extract on Growth, Gut Health, Carcass Quality, and Welfare of Broiler Chickens
Published 2025-01-01“…These effects could potentially be attributed to the reduction in inflammation and the enhanced utilization of nutrients. …”
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4802
The methyl-CpG binding domain 2 regulates peptidylarginine deiminase 4 expression and promotes neutrophil extracellular trap formation via the Janus kinase 2 signaling pathway in e...
Published 2025-12-01“…Inhibiting the expression of MBD2, JAK2, and PAD4 reduced NETs formation and decreased airway inflammation scores, total cell counts and neutrophil counts in BALF, and percentage of Th2 and Th17 cell in lung tissues, whereas increasing Treg cell counts. …”
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4803
Effects of heat stress abatement on behavioral response in lactating dairy cows prior to and following an intramammary lipopolysaccharide infusion
Published 2025-02-01“…However, deprivation of evaporative cooling does not have a significant effect on the lactating cow's behavioral responses to LPS induced mammary inflammation.…”
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4804
Prognostic value of inflammatory markers for all-cause mortality in patients with acute myocardial infarction in the coronary care unit: a retrospective study based on MIMIC-IV dat...
Published 2025-01-01“…This paper was to verify the correlation of neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), platelet-to-lymphocyte ratio (PLR), and systemic inflammation response index (SIRI) with all-cause mortality for AMI patients in the CCU.MethodsAdult patients diagnosed with AMI and admitted to CCU were selected from the MIMIC-IV database. …”
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4805
Correlation analysis of the impact of Clonorchis sinensis juvenile on gut microbiota and transcriptome in mice
Published 2025-02-01“…Pathological analyses revealed that C. sinensis juvenile triggered liver inflammation, promoted intestinal villi growth, and augmented goblet cell numbers in the ileum. …”
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4806
Effects of biologic therapy on novel indices of lung inhomogeneity in patients with severe type-2 high asthma
Published 2025-02-01“…Responders, unlike Non-Responders, experienced significant improvements in symptoms and FEV1 % predicted (Δ pre-BD FEV115±15% pred, p<0.001) and included a higher proportion of patients in clinical remission at 1 year.Conclusion σlnCl is strongly associated with systemic eosinophilic inflammation in severe type-2 high asthma. An early σlnCl response following anti-IL5 biologics identifies patients more likely to experience improvements in symptoms and lung function when systemic eosinophils are depleted. σlnCl may provide a sensitive route for tracking inflammation involving the small airways.…”
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4807
Phase-dependent iron depletion differentially regulates the niche of intestinal stem cells in experimental colitis via ERK/STAT3 signaling pathway
Published 2025-01-01“…IntroductionUlcerative colitis (UC) is a global gastrointestinal disease, which is mainly caused by both dysfunctional epithelial barrier and inflammation response. Iron is a critical fundamental element for both the maintenance of homeostasis and the mediation of inflammation in many tissues. …”
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4808
Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway
Published 2025-02-01“…FMT alleviated ETEC-induced gut barrier injury and intestinal inflammation in the AIMD model. A. muciniphila was identified as a key strain in FMT to promote the proliferation and differentiation of intestinal stem cells by mediating the Wnt/β-catenin signaling pathway.…”
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4809
Cerium-based nanoplatform for severe acute pancreatitis: Achieving enhanced anti-inflammatory effects through calcium homeostasis restoration and oxidative stress mitigation
Published 2025-04-01“…Mechanistically, the administration of the nanoplatform reversed metabolic abnormalities in pancreatic tissue and inhibited the signaling pathways that promote inflammation progression in SAP. This nanoplatform provides a new strategy for SAP treatment, with clinical translation prospects, through ion homeostasis regulation and pancreatic oxidative stress inhibition.…”
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4810
Diagnostics and treatment of Clostridium difficile-associated disease: Guidelines of the Russian gastroenterological association
Published 2018-08-01“…Clostridium difficile-associated disease develops at disorders of intestinal microbiome with excessive colonization of C. difficile which toxins cause colonic inflammation and damage. C. difficile toxins A and B are major virulence factors causing damage of intestinal wall and inflammation due to damage of intestinal epithelial barrier, induction of proinflammatory cytokines, apoptosis and a necrosis of epithelial cells. …”
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4811
Inflammatory Markers and Severity in COVID-19 Patients with Clostridioides Difficile Co-Infection: A Retrospective Analysis Including Subgroups with Diabetes, Cancer, and Elderly
Published 2025-01-01“…Conclusions: Concurrent CDI intensifies systemic inflammation and adverse clinical trajectories in hospitalized COVID-19 patients. …”
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4812
Bacillus subtilis HGCC-1 improves growth performance and liver health via regulating gut microbiota in golden pompano
Published 2025-01-01“…Besides, HGCC-1 improved liver health and alleviated hepatic steatosis and inflammation. Furthermore, Bacillus subtilis HGCC-1 enhanced intestinal lipid absorption, promoted hepatic utilization of dietary fat by improving hepatic lipid uptake/transport and fatty acid β-oxidation to provide energy, and reduced hepatic TG level (P < 0.05), which may be the potential mechanism of Bacillus subtilis HGCC-1-mediated growth promotion. …”
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4813
Health and Cellular Impacts of Air Pollutants: From Cytoprotection to Cytotoxicity
Published 2012-01-01“…Environmental air pollutants are a heterogeneous mixture of particles suspended into a liquid and gaseous phase which trigger the disruption of redox homeostasis—known under the term of cellular oxidative stress—in relation with the establishment of inflammation and cell death via necrosis, apoptosis, or autophagy. …”
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4814
PPAR-Alpha Agonist Fenofibrate Combined with Octreotide Acetate in the Treatment of Acute Hyperlipidemia Pancreatitis
Published 2021-01-01“…The synergistic inhibitory effect proves that the combined treatment is beneficial to control inflammation, protect liver function, and improve the prognosis of patients. …”
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4815
cGAS/STING signaling pathway in gynecological malignancies: From molecular mechanisms to therapeutic values
Published 2025-01-01“…The article outlines cGAS/STING’s influence on tumor microenvironments, immune surveillance, and inflammation, with emphasis on molecular mechanisms driving cancer progression. …”
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4816
Symphysis Pubis Osteomyelitis with Bilateral Adductor Muscles Abscess
Published 2014-01-01“…There have been various reports in the literature of inflammation and osteomyelitis as well as septic arthritis of pubic symphysis. …”
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4817
The impact of cardiac complications on COVID-19 outcomes
Published 2024-08-01“…Possible mechanisms of cardiac damage are the high affinity of the SARS-CoV-2 adhesion protein to angiotensin-converting enzyme 2 receptors, cytokine storm, ischemia, inflammation, and acute respiratory distress syndrome. …”
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4818
Cytokine Immunopathogenesis of Enterovirus 71 Brain Stem Encephalitis
Published 2012-01-01“…Administration of intravenous immunoglobulin and milrinone, a phosphodiesterase inhibitor, has been shown to modulate inflammation, to reduce sympathetic overactivity, and to improve survival in patients with EV71 autonomic nervous system dysregulation and pulmonary edema.…”
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4819
Hydroxyapatite Deposition Disease as Cause of Atraumatic Shoulder Pain: A Case Report
Published 2025-01-01“…Introduction: Hydroxyapatite deposition disease (HADD) is caused by the presence of hydroxyapatite crystals in periarticular spaces oftentimes leading to inflammation, pain, and decreased range of motion. Case Report: A 40-year-old right hand dominant female presented with three days of atraumatic right shoulder pain. …”
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4820
A Rare Sequela of Acute Disseminated Encephalomyelitis
Published 2014-01-01“…Primary and secondary immune responses contribute to inflammation and subsequent demyelination, but the exact pathogenesis is still unknown. …”
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